Stephan Taylor

Summary

Affiliation: University of Michigan
Country: USA

Publications

  1. pmc Brain mapping biomarkers of socio-emotional processing in schizophrenia
    Stephan F Taylor
    Department of Psychiatry, University of Michigan, Rachel Upjohn Building, 4250 Plymouth Road, Ann Arbor, MI 48109 2700, USA
    Schizophr Bull 38:73-80. 2012
  2. pmc Social appraisal in chronic psychosis: role of medial frontal and occipital networks
    Stephan F Taylor
    Department of Psychiatry, University of Michigan, Rachel Upjohn Building, 4250 Plymouth Rd, Ann Arbor MI 48109 2700, USA
    J Psychiatr Res 45:526-38. 2011
  3. pmc Meta-analysis of functional neuroimaging studies of emotion perception and experience in schizophrenia
    Stephan F Taylor
    Department of Psychiatry, University of Michigan, Ann Arbor, Michigan 48109 2700, USA
    Biol Psychiatry 71:136-45. 2012
  4. ncbi request reprint Medial frontal hyperactivity in reality distortion
    Stephan F Taylor
    Department of Psychiatry, University of Michigan Medical Center, Ann Arbor, Michigan 48109 5765, USA
    Biol Psychiatry 61:1171-8. 2007
  5. ncbi request reprint Neural systems for error monitoring: recent findings and theoretical perspectives
    Stephan F Taylor
    Department of Psychiatry, University of Michigan, Ann Arbor, Michigan, USA
    Neuroscientist 13:160-72. 2007
  6. ncbi request reprint Medial frontal cortex activity and loss-related responses to errors
    Stephan F Taylor
    Department of Psychiatry, University of Michigan, Ann Arbor, Michigan 48109, USA
    J Neurosci 26:4063-70. 2006
  7. ncbi request reprint Neural correlates of emotion regulation in psychopathology
    Stephan F Taylor
    University of Michigan Department of Psychiatry, 4250 Plymouth Rd, Ann Arbor, MI 48109 5765, USA
    Trends Cogn Sci 11:413-8. 2007
  8. ncbi request reprint Neural response to emotional salience in schizophrenia
    Stephan F Taylor
    Department of Psychiatry, University of Michigan, Ann Arbor, MI 48109, USA
    Neuropsychopharmacology 30:984-95. 2005
  9. ncbi request reprint Subjective rating of emotionally salient stimuli modulates neural activity
    Stephan F Taylor
    Department of Psychiatry, University of Michigan, Ann Arbor, MI 48109, USA
    Neuroimage 18:650-9. 2003
  10. ncbi request reprint A functional anatomic study of emotion in schizophrenia
    Stephan F Taylor
    Department of Psychiatry, University of Michigan Medical Center, UH 9D Box 0118, 1500 E Medical Center Drive, Ann Arbor MI 48109 0118, USA
    Schizophr Res 58:159-72. 2002

Research Grants

Detail Information

Publications50

  1. pmc Brain mapping biomarkers of socio-emotional processing in schizophrenia
    Stephan F Taylor
    Department of Psychiatry, University of Michigan, Rachel Upjohn Building, 4250 Plymouth Road, Ann Arbor, MI 48109 2700, USA
    Schizophr Bull 38:73-80. 2012
    ..Here, we provide a critical appraisal of the ability of candidate socio-emotional tasks to identify putative biomarkers and recommendations for future directions in this rapidly moving research domain...
  2. pmc Social appraisal in chronic psychosis: role of medial frontal and occipital networks
    Stephan F Taylor
    Department of Psychiatry, University of Michigan, Rachel Upjohn Building, 4250 Plymouth Rd, Ann Arbor MI 48109 2700, USA
    J Psychiatr Res 45:526-38. 2011
    ....
  3. pmc Meta-analysis of functional neuroimaging studies of emotion perception and experience in schizophrenia
    Stephan F Taylor
    Department of Psychiatry, University of Michigan, Ann Arbor, Michigan 48109 2700, USA
    Biol Psychiatry 71:136-45. 2012
    ..To identify more consistent patterns of dysfunction, a meta-analysis of functional imaging studies of emotion was undertaken...
  4. ncbi request reprint Medial frontal hyperactivity in reality distortion
    Stephan F Taylor
    Department of Psychiatry, University of Michigan Medical Center, Ann Arbor, Michigan 48109 5765, USA
    Biol Psychiatry 61:1171-8. 2007
    ..The amygdala interacts with MPFC, also carries out socioemotional processing, and has been implicated in schizophrenia; thus, we also tested the hypothesis that patients would exhibit aberrant amygdala activity...
  5. ncbi request reprint Neural systems for error monitoring: recent findings and theoretical perspectives
    Stephan F Taylor
    Department of Psychiatry, University of Michigan, Ann Arbor, Michigan, USA
    Neuroscientist 13:160-72. 2007
    ....
  6. ncbi request reprint Medial frontal cortex activity and loss-related responses to errors
    Stephan F Taylor
    Department of Psychiatry, University of Michigan, Ann Arbor, Michigan 48109, USA
    J Neurosci 26:4063-70. 2006
    ..The findings support the hypothesis that the rostral extent of the MFC (rACC) processes loss-related responses to errors, and individual differences may account for some of the reported variation of error-related foci in the MFC...
  7. ncbi request reprint Neural correlates of emotion regulation in psychopathology
    Stephan F Taylor
    University of Michigan Department of Psychiatry, 4250 Plymouth Rd, Ann Arbor, MI 48109 5765, USA
    Trends Cogn Sci 11:413-8. 2007
    ..We summarize recent research to suggest that networks of direct and indirect pathways exist by which cognition can regulate pathological emotion, and the inter-relationships of specific nodes within the networks need to be characterized...
  8. ncbi request reprint Neural response to emotional salience in schizophrenia
    Stephan F Taylor
    Department of Psychiatry, University of Michigan, Ann Arbor, MI 48109, USA
    Neuropsychopharmacology 30:984-95. 2005
    ..Reduced modulation of visual cortex by emotionally salient stimuli also suggests a failure to organize cerebral activity at a global level...
  9. ncbi request reprint Subjective rating of emotionally salient stimuli modulates neural activity
    Stephan F Taylor
    Department of Psychiatry, University of Michigan, Ann Arbor, MI 48109, USA
    Neuroimage 18:650-9. 2003
    ..For both RTNG and PSVW, subjects activated the left fusiform gyrus. The results support the proposition that task instructions about how subjects should process evocative stimuli can affect neural activity...
  10. ncbi request reprint A functional anatomic study of emotion in schizophrenia
    Stephan F Taylor
    Department of Psychiatry, University of Michigan Medical Center, UH 9D Box 0118, 1500 E Medical Center Drive, Ann Arbor MI 48109 0118, USA
    Schizophr Res 58:159-72. 2002
    ..Overall, the data are consistent with a general failure to process salient stimuli in schizophrenia, and the findings support the involvement of the amygdala in the positive symptoms of schizophrenia...
  11. ncbi request reprint The effect of graded aversive stimuli on limbic and visual activation
    S F Taylor
    Department of Psychiatry, University of Michigan Medical Center, UH 9D Box 0118, Ann Arbor, MI 48109 0118, USA
    Neuropsychologia 38:1415-25. 2000
    ..In addition, they suggest that pictorial complexity, as indexed by our semantic measure, does not account for the modulation of visual cortex by aversive, emotional stimuli...
  12. ncbi request reprint Cerebral blood flow activation and functional lesions in schizophrenia
    S F Taylor
    University of Michigan Department of Psychiatry, University Hospital, Ann Arbor 48109 0116, USA
    Schizophr Res 19:129-40. 1996
    ....
  13. ncbi request reprint The effect of emotional content on visual recognition memory: a PET activation study
    S F Taylor
    Department of Psychiatry, University of Michigan, Ann Arbor, Michigan 48109, USA
    Neuroimage 8:188-97. 1998
    ..Instead of distinct neuroanatomical systems for emotion augmenting memory, we found that emotionally salient stimuli appeared to enhance processing of early sensory input during visual recognition...
  14. ncbi request reprint Corticolimbic blood flow during nontraumatic emotional processing in posttraumatic stress disorder
    K Luan Phan
    Department of Psychiatry, Pritzker School of Medicine, The University of Chicago, Chicago, Ill, USA
    Arch Gen Psychiatry 63:184-92. 2006
    ..However, the relationship between activity in these regions and general emotional processing unrelated to traumatic experience has not been fully examined...
  15. ncbi request reprint Corticolimbic blood flow in posttraumatic stress disorder during script-driven imagery
    Jennifer C Britton
    Neuroscience Program, University of Michigan, Michigan, USA
    Biol Psychiatry 57:832-40. 2005
    ..The present study examined both PTSD-specific and trauma-specific regional cerebral blood flow (rCBF) patterns during script-driven imagery...
  16. ncbi request reprint Neural correlates of social and nonsocial emotions: An fMRI study
    Jennifer C Britton
    Neuroscience Program, University of Michigan, Ann Arbor, MI 48109
    Neuroimage 31:397-409. 2006
    ..Overall, these findings highlight that sociality has a key role in processing emotional valence, which may have implications for patient populations with social and emotional deficits...
  17. ncbi request reprint Activation of the medial prefrontal cortex and extended amygdala by individual ratings of emotional arousal: a fMRI study
    K Luan Phan
    Department of Psychiatry, University of Michigan, Ann Arbor, Michigan 48109 0118, USA
    Biol Psychiatry 53:211-5. 2003
    ....
  18. ncbi request reprint Error-related hyperactivity of the anterior cingulate cortex in obsessive-compulsive disorder
    Kate Dimond Fitzgerald
    Department of Psychiatry, University of Michigan, Ann Arbor, Michigan, 48109 0118, USA
    Biol Psychiatry 57:287-94. 2005
    ..In this functional magnetic resonance imaging (fMRI) study, we sought to further localize error-processing differences within the ACC of OCD patients compared with healthy subjects...
  19. doi request reprint Medial prefrontal cortex and right insula activity predict plasma ACTH response to trauma recall
    Anthony P King
    Psychiatry, University of Michigan, Ann Arbor, MI, USA
    Neuroimage 47:872-80. 2009
    ..These results support the hypotheses that right insula is involved in psychological activation of the LHPA axis and that rostral mPFC may negatively modulate LHPA axis responses...
  20. ncbi request reprint Facial expressions and complex IAPS pictures: common and differential networks
    Jennifer C Britton
    Department of Neuroscience, University of Michigan, Ann Arbor, MI 48109, USA
    Neuroimage 31:906-19. 2006
    ..For the most part, these regions were activated in response to all specific emotions; however, some regions responded only to a subset...
  21. pmc Topographic analysis of individual activation patterns in medial frontal cortex in schizophrenia
    Emily R Stern
    Department of Psychiatry, University of Michigan, Ann Arbor, MI 48105, USA
    Hum Brain Mapp 30:2146-56. 2009
    ....
  22. pmc Updating beliefs for a decision: neural correlates of uncertainty and underconfidence
    Emily R Stern
    Department of Psychiatry, University of Michigan, Ann Arbor, Michigan 48109, USA
    J Neurosci 30:8032-41. 2010
    ....
  23. doi request reprint Pilot study of response inhibition and error processing in the posterior medial prefrontal cortex in healthy youth
    Kate Dimond Fitzgerald
    Department of Psychiatry, University of Michigan, Ann Arbor, MI 48109, USA
    J Child Psychol Psychiatry 49:986-94. 2008
    ..Developmental neuroimaging studies of response inhibition have found pMFC activation, but the possible contribution of error-related activation during inhibitory processing has not been well studied in youth...
  24. doi request reprint Decision-related loss: regret and disappointment
    Hannah Faye Chua
    Department of Psychology, University of Michigan, Ann Arbor, MI 48109, USA
    Neuroimage 47:2031-40. 2009
    ....
  25. pmc Low-frequency BOLD fluctuations demonstrate altered thalamocortical connectivity in schizophrenia
    Robert C Welsh
    Department of Radiology, University of Michigan, Ann Arbor, MI 48109 0553, USA
    Schizophr Bull 36:713-22. 2010
    ..These data support a disruption model of the thalamocortical network and are consistent with a disconnection hypothesis of schizophrenia...
  26. doi request reprint Trait anxiety modulates anterior cingulate activation to threat interference
    Heide Klumpp
    Department of Psychiatry, University of Michigan Ann Arbor, 4250 Plymouth Road, Ann Arbor, MI 48109, USA
    Depress Anxiety 28:194-201. 2011
    ..g. anterior cingulate cortex, "ACC") might play a role. In this study, we explored the hypothesis that trait anxiety would be associated with ACC activity in an attentional control task with varying levels of threat interference...
  27. doi request reprint Handedness, dexterity, and motor cortical representations
    Jessica A Bernard
    Department of Psychology, University of Michigan, Ann Arbor, Michigan, USA
    J Neurophysiol 105:88-99. 2011
    ..However, it is not clear whether iMEPs are directly mediated via ipsilateral corticospinal projections or are transcallosally transmitted...
  28. pmc Emotional experience predicts social adjustment independent of neurocognition and social cognition in schizophrenia
    Ivy F Tso
    Department of Psychiatry, University of Michigan, 4250 Plymouth Road, Ann Arbor, MI 48109, USA
    Schizophr Res 122:156-63. 2010
    ..Emotional abnormalities are prominent features of schizophrenia. While the capacity for emotions is essential to social adaptation, little is known about the role of emotional experience in the social dysfunction observed in schizophrenia...
  29. pmc The development of performance-monitoring function in the posterior medial frontal cortex
    Kate Dimond Fitzgerald
    Department of Psychiatry, University of Michigan, Ann Arbor, MI 48104, USA
    Neuroimage 49:3463-73. 2010
    ..To characterize the development of pMFC-based performance monitoring functions, we segregated interference and error-processing, while statistically controlling for performance...
  30. pmc 'Do I like this person?' A network analysis of midline cortex during a social preference task
    Ashley C Chen
    Neuroscience Program, University of Michigan, USA
    Neuroimage 51:930-9. 2010
    ....
  31. doi request reprint Chronic medication does not affect hyperactive error responses in obsessive-compulsive disorder
    Emily R Stern
    Department of Psychiatry, University of Michigan, Ann Arbor, Michigan 48106, USA
    Psychophysiology 47:913-20. 2010
    ..The absence in patients of a relationship between ERN amplitude and anxiety/depression, as was found in controls, suggests that elevated error signals in OCD may be disorder-specific...
  32. pmc Metabolic syndrome and insulin resistance in schizophrenia patients receiving antipsychotics genotyped for the methylenetetrahydrofolate reductase (MTHFR) 677C/T and 1298A/C variants
    Vicki L Ellingrod
    University of Michigan College of Pharmacy, Department of Clinical Sciences, School of Medicine, Ann Arbor 48109, USA
    Schizophr Res 98:47-54. 2008
    ....
  33. ncbi request reprint Habituation of rostral anterior cingulate cortex to repeated emotionally salient pictures
    K Luan Phan
    Department of Psychiatry, University of Michigan, Ann Arbor, Ann Arbor, MI, USA
    Neuropsychopharmacology 28:1344-50. 2003
    ..These findings highlight the phasic activity of the rACC in emotional processing consistent with habituation...
  34. ncbi request reprint Valence, gender, and lateralization of functional brain anatomy in emotion: a meta-analysis of findings from neuroimaging
    Tor D Wager
    Department of Psychology, University of Michigan, Ann Arbor, MI 48109, USA
    Neuroimage 19:513-31. 2003
    ..The study provides evidence that lateralization of emotional activity is more complex and region-specific than predicted by previous theories of emotion and the brain...
  35. ncbi request reprint A functional neuroimaging study of motivation and executive function
    Stephan F Taylor
    Department of Psychiatry, University of Michigan, Ann Arbor, MI 48109 0118, USA
    Neuroimage 21:1045-54. 2004
    ..Areas of overlap and interaction may integrate information about value, or they may represent a general effect of motivation increasing neural effort...
  36. ncbi request reprint Extended amygdala and emotional salience: a PET activation study of positive and negative affect
    Israel Liberzon
    Department of Psychiatry, University of Michigan, Ann Arbor, USA
    Neuropsychopharmacology 28:726-33. 2003
    ....
  37. ncbi request reprint Altered central micro-opioid receptor binding after psychological trauma
    Israel Liberzon
    Department of Psychiatry, University of Michigan Medical School, Ann Arbor, Michigan 48109 0118, USA
    Biol Psychiatry 61:1030-8. 2007
    ..The mu-opioid neurotransmitter system, implicated in responses to stress and suppression of pain, is distributed in and is thought to regulate the function of brain regions that are implicated in affective processing...
  38. ncbi request reprint Functional neuroanatomy of emotion: a meta-analysis of emotion activation studies in PET and fMRI
    K Luan Phan
    Department of Psychiatry, University of Michigan, Ann Arbor, Michigan 48109, USA
    Neuroimage 16:331-48. 2002
    ..This review provides a critical comparison of findings across individual studies and suggests that separate brain regions are involved in different aspects of emotion...
  39. ncbi request reprint Deep brain stimulation for refractory obsessive-compulsive disorder
    James L Abelson
    Department of Psychiatry, University of Michigan, Trauma, Stress and Anxiety Research Group, Ann Arbor, Michigan, USA
    Biol Psychiatry 57:510-6. 2005
    ..Nondestructive, electrical stimulation (deep brain stimulation; DBS) has proven an effective alternative to ablative surgery for neurological indications, suggesting potential utility in place of capsulotomy for OCD...
  40. pmc mu-Opioid receptors and limbic responses to aversive emotional stimuli
    Israel Liberzon
    Department of Psychiatry, Veterans Administration Medical Center, University of Michigan, Ann Arbor, MI 48105, USA
    Proc Natl Acad Sci U S A 99:7084-9. 2002
    ..This is consistent with an inhibitory/anxiolytic role of the endogenous opioid system in limbic regions of the temporal lobe and basal forebrain...
  41. ncbi request reprint Paralimbic and medial prefrontal cortical involvement in neuroendocrine responses to traumatic stimuli
    Israel Liberzon
    Department of Psychiatry, University of Michigan Medical School, Ann Arbor, MI, USA
    Am J Psychiatry 164:1250-8. 2007
    ..The authors used [(15)O]H(2)O positron emission tomography (PET) on subjects with posttraumatic stress disorder (PTSD) to study these circuits...
  42. pmc Hyperactive error responses and altered connectivity in ventromedial and frontoinsular cortices in obsessive-compulsive disorder
    Emily R Stern
    Department of Psychiatry, University of Michigan, Ann Arbor, Michigan 48109, USA
    Biol Psychiatry 69:583-91. 2011
    ..While OCD has been associated with an increased neural response to errors, the influence of motivational factors on this effect remains poorly understood...
  43. ncbi request reprint Differential subjective and psychophysiological responses to socially and nonsocially generated emotional stimuli
    Jennifer C Britton
    Neuroscience Program, University of Michigan, USA
    Emotion 6:150-5. 2006
    ..Heart rate deceleration was more responsive to nonsocially generated emotions. Taken together, these findings suggest that sociality affects the physiological profile of responses to emotional valence...
  44. ncbi request reprint Clinical equivalence of generic clozapine
    Daniel J Healy
    Department of Psychiatry, University of Michigan Health System, 1500 E Medical Center Drive, Ann Arbor, MI 48109 0020, USA
    Community Ment Health J 41:393-8. 2005
    ..To determine if mental health service utilization increases when patients are converted to generic clozapine...
  45. ncbi request reprint Neuroticism associated with neural activation patterns to positive stimuli
    Jennifer C Britton
    Department of Neuroscience, University of Michigan, Ann Arbor, MI, USA
    Psychiatry Res 156:263-7. 2007
    ..Neuroticism directly correlated with dorsomedial prefrontal cortex activation in response to positive stimuli. Dorsomedial prefrontal cortex correlations may reflect increased self-association in individuals with high neuroticism...
  46. ncbi request reprint Neural correlates of individual ratings of emotional salience: a trial-related fMRI study
    K Luan Phan
    Department of Psychiatry and Behvioral Neuroscience, Wayne State University School of Medicine, Detroit, MI 48201, USA
    Neuroimage 21:768-80. 2004
    ..The findings highlight both overlapping and segregated neural representations of intrinsic value and personal relevance during the appraisal of emotional stimuli...
  47. ncbi request reprint When the going gets tough, the cingulate gets going
    William J Gehring
    Nat Neurosci 7:1285-7. 2004
  48. ncbi request reprint Working memory for complex scenes: age differences in frontal and hippocampal activations
    Denise C Park
    The Beckman Institute, University of Illinois at Urbana Champaign 61801, USA
    J Cogn Neurosci 15:1122-34. 2003
    ..Thus, we demonstrate qualitatively different engagement of both frontal and hippocampal structures in older adults in a working memory task, despite behavioral equivalence...
  49. ncbi request reprint Functional neuroimaging studies of human emotions
    K Luan Phan
    Department of Psychiatry and Behavioral Neurosciences, Wayne State University, Detroit, Michigan 48201, USA
    CNS Spectr 9:258-66. 2004
    ..This paper will review observations in several regions of interest in limbic (eg, amygdala, anterior cingulate cortex) and paralimbic (eg, medial prefrontal cortex, insula) brain regions in emotional responding...
  50. ncbi request reprint Clozapine-associated cardiomyopathy
    K Luan Dinh Phan
    Psychosomatics 43:248. 2002

Research Grants10

  1. Neuroanatomy of Emotion in Treatment Resistant Psychosis
    Stephan Taylor; Fiscal Year: 2006
    ..abstract_text> ..
  2. Functional Neuroanatomy of Obsessive Compulsive Disorder
    Stephan Taylor; Fiscal Year: 2009
    ..Successful completion of the project should lead to an improved understanding of the role of specific brain regions in generating the symptoms of OCD. ..