Affiliation: University of Michigan Medical School
Location: Ann Arbor, USA
- Generation of recombinant norovirus-like particles (VLP) in the human endothelial kidney cell line 293TS Taube
Robert Koch Institut, Berlin, Germany
Arch Virol 150:1425-31. 2005..The produced particles were stable for at least 2.5 months at 4 degrees C...
- Transient or persistent norovirus infection does not alter the pathology of Salmonella typhimurium induced intestinal inflammation and fibrosis in micePeter D R Higgins
Division of Gastroenterology and Hepatology, Department of Internal Medicine, University of Michigan Medical Center, Medical Science Research Building One, 1150 West Medical Center Drive, Ann Arbor, MI 48109 5682, United States
Comp Immunol Microbiol Infect Dis 34:247-57. 2011..We hypothesize that this is particularly important in cases of research models that use immunocompromised mice, which could be more sensitive to MNV infection-induced changes...
- High-resolution cryo-electron microscopy structures of murine norovirus 1 and rabbit hemorrhagic disease virus reveal marked flexibility in the receptor binding domainsUmesh Katpally
Donald Danforth Plant Science Center, 975 North Warson Road, Saint Louis, MO 63132, USA
J Virol 84:5836-41. 2010..Connections between the P and shell domains and between the floating P domains were modeled. This observed P-domain flexibility likely facilitates virus-host receptor interactions...
- High-resolution x-ray structure and functional analysis of the murine norovirus 1 capsid protein protruding domainStefan Taube
Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA
J Virol 84:5695-705. 2010..Therefore, we hypothesize that these loop regions and the flexibility of the P domains play important roles during MNV-1 binding to the cell surface...
- Murine norovirus-1 entry into permissive macrophages and dendritic cells is pH-independentJeffrey W Perry
Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI 48109 5620, United States
Virus Res 143:125-9. 2009..These data indicate that MNV-1 enters permissive cells in a pH-independent manner...
- Low-density lipoprotein receptor variants are associated with spontaneous and treatment-induced recovery from hepatitis C virus infectionAndreas Mas Marques
Robert Koch Institut, Berlin, Germany
Infect Genet Evol 9:847-52. 2009..1413G>A heterozygosity (33.0% vs. 46.1%, p=0.023). The data indicate that LDLR alterations are correlated with response to interferon-based combination therapy and with self-limitation of HCV 1 infection...
- Ganglioside-linked terminal sialic acid moieties on murine macrophages function as attachment receptors for murine norovirusesStefan Taube
Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan 48109 5620, USA
J Virol 83:4092-101. 2009..In conclusion, our data indicate that MNV can use terminal SA on gangliosides as attachment receptors during binding to murine macrophages...
- A functional toll-like receptor 8 variant is associated with HIV disease restrictionD Y Oh
Institute of Microbiology and Hygiene, Charite Universitatsmedizin Berlin, Berlin, Germany
J Infect Dis 198:701-9. 2008..Presently, very little is known about the influence of TLR8 genetic variation on susceptibility to and progression of HIV disease...
- A Toll-like receptor 7 single nucleotide polymorphism protects from advanced inflammation and fibrosis in male patients with chronic HCV-infectionEckart Schott
Department of Hepatology and Gastroenterology, CVK, Charite Universitatsmedizin Berlin, Germany
J Hepatol 47:203-11. 2007..Since HCV is an RNA virus, a role for TLR7 in the immune response against HCV is likely. No systematic analysis of TLR7 single nucleotide polymorphisms (SNPs) has been published...
- Glycosphingolipids as receptors for non-enveloped virusesStefan Taube
Department of Microbiology and Immunology, University of Michigan Medical School, 5622 Medical Sciences Bldg II, 1150 West Medical Center Dr, Ann Arbor, MI 48109, USA E Mails S T M J
Viruses 2:1011-49. 2010..In this review, we summarize the role of glycosphingolipids as receptors for members of the non-enveloped calici-, rota-, polyoma- and parvovirus families...