Ralph Tarter

Summary

Affiliation: University of Pittsburgh
Country: USA

Publications

  1. ncbi request reprint Predictors of marijuana use in adolescents before and after licit drug use: examination of the gateway hypothesis
    Ralph E Tarter
    Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, PA 15261, USA
    Am J Psychiatry 163:2134-40. 2006
  2. ncbi request reprint Neurobehavioral disinhibition in childhood predicts early age at onset of substance use disorder
    Ralph E Tarter
    University of Pittsburgh, Department of Pharmaceutical Sciences, Pittsburgh, PA 15261, USA
    Am J Psychiatry 160:1078-85. 2003
  3. ncbi request reprint Developmental trajectory classes in substance use disorder etiology
    Levent Kirisci
    University of Pittsburgh, School of Pharmacy, Pittsburgh, PA 15261, USA
    Psychol Addict Behav 21:287-96. 2007
  4. pmc Computer adaptive testing of liability to addiction: identifying individuals at risk
    Levent Kirisci
    Department of Pharmaceutical Sciences, Center for Education and Drug Abuse Research, University of Pittsburgh, 3520 Forbes Avenue, Suite 203, Pittsburgh, PA 15213, USA
    Drug Alcohol Depend 123:S79-86. 2012
  5. pmc Screening current and future diagnosis of psychiatric disorders using the Revised Drug Use Screening Inventory
    Levent Kirisci
    Center for Education and Drug Abuse Research, Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
    Am J Drug Alcohol Abuse 34:653-65. 2008
  6. pmc Premature mortality among males with substance use disorders
    Jack R Cornelius
    Center for Education and Drug Abuse Research CEDAR, University of Pittsburgh, 3811 O Hara Street, PAARC Suite, Pittsburgh, PA 15213, USA
    Addict Behav 33:156-60. 2008
  7. pmc Prediction of cannabis use disorder between boyhood and young adulthood: clarifying the phenotype and environtype
    Levent Kirisci
    Center for Education and Drug Abuse Research, University of Pittsburgh, School of Pharmacy, Pittsburgh, Pennsylvania 15261, USA
    Am J Addict 18:36-47. 2009
  8. ncbi request reprint Detection of youth at high risk for substance use disorders: a longitudinal study
    Levent Kirisci
    School of Pharmacy, University of Pittsburgh, 707 Salk Hall, Pittsburgh, PA 15261, USA
    Psychol Addict Behav 19:243-52. 2005
  9. ncbi request reprint Early age of first sexual intercourse and affiliation with deviant peers predict development of SUD: a prospective longitudinal study
    Jack R Cornelius
    Center for Education and Drug Abuse Research CEDAR, University of Pittsburgh, 3811 O Hara Street, PAARC Suite, Pittsburgh, PA 15213, USA
    Addict Behav 32:850-4. 2007
  10. pmc PTSD contributes to teen and young adult cannabis use disorders
    Jack R Cornelius
    Center for Education and Drug Abuse Research, University of Pittsburgh, 3811 O Hara Street, PAARC Suite, Pittsburgh, PA 15213, USA
    Addict Behav 35:91-4. 2010

Research Grants

Detail Information

Publications47

  1. ncbi request reprint Predictors of marijuana use in adolescents before and after licit drug use: examination of the gateway hypothesis
    Ralph E Tarter
    Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, PA 15261, USA
    Am J Psychiatry 163:2134-40. 2006
    ..They also evaluated the accuracy of the "gateway sequence" (illicit drug use following licit drugs) for predicting a diagnosis of substance use disorder...
  2. ncbi request reprint Neurobehavioral disinhibition in childhood predicts early age at onset of substance use disorder
    Ralph E Tarter
    University of Pittsburgh, Department of Pharmaceutical Sciences, Pittsburgh, PA 15261, USA
    Am J Psychiatry 160:1078-85. 2003
    ....
  3. ncbi request reprint Developmental trajectory classes in substance use disorder etiology
    Levent Kirisci
    University of Pittsburgh, School of Pharmacy, Pittsburgh, PA 15261, USA
    Psychol Addict Behav 21:287-96. 2007
    ....
  4. pmc Computer adaptive testing of liability to addiction: identifying individuals at risk
    Levent Kirisci
    Department of Pharmaceutical Sciences, Center for Education and Drug Abuse Research, University of Pittsburgh, 3520 Forbes Avenue, Suite 203, Pittsburgh, PA 15213, USA
    Drug Alcohol Depend 123:S79-86. 2012
    ..This study was conducted to develop and evaluate a computer adaptive test (CAT) version of the TLI to identifying individuals at risk for SUD...
  5. pmc Screening current and future diagnosis of psychiatric disorders using the Revised Drug Use Screening Inventory
    Levent Kirisci
    Center for Education and Drug Abuse Research, Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
    Am J Drug Alcohol Abuse 34:653-65. 2008
    ..Thus in addition to its utility for detecting problems that precede and correlate with substance abuse, the DUSI-R is cost-efficient for screening youths for mental disorders...
  6. pmc Premature mortality among males with substance use disorders
    Jack R Cornelius
    Center for Education and Drug Abuse Research CEDAR, University of Pittsburgh, 3811 O Hara Street, PAARC Suite, Pittsburgh, PA 15213, USA
    Addict Behav 33:156-60. 2008
    ..The objective of this study was to assess whether the presence of SUD or ASP is associated with early mortality among males (fathers) in a predominantly community sample, using a 15-year prospective longitudinal study design...
  7. pmc Prediction of cannabis use disorder between boyhood and young adulthood: clarifying the phenotype and environtype
    Levent Kirisci
    Center for Education and Drug Abuse Research, University of Pittsburgh, School of Pharmacy, Pittsburgh, Pennsylvania 15261, USA
    Am J Addict 18:36-47. 2009
    ....
  8. ncbi request reprint Detection of youth at high risk for substance use disorders: a longitudinal study
    Levent Kirisci
    School of Pharmacy, University of Pittsburgh, 707 Salk Hall, Pittsburgh, PA 15261, USA
    Psychol Addict Behav 19:243-52. 2005
    ..These results indicate that monitoring social adjustment during the transition from childhood to mid-adolescence is important for identifying youth at very high risk for succumbing to SUD by young adulthood...
  9. ncbi request reprint Early age of first sexual intercourse and affiliation with deviant peers predict development of SUD: a prospective longitudinal study
    Jack R Cornelius
    Center for Education and Drug Abuse Research CEDAR, University of Pittsburgh, 3811 O Hara Street, PAARC Suite, Pittsburgh, PA 15213, USA
    Addict Behav 32:850-4. 2007
    ..The objective of this study was to assess whether early onset of sexual intercourse and affiliation with deviant peers serve as predictors of the development of SUD, using a prospective longitudinal study design...
  10. pmc PTSD contributes to teen and young adult cannabis use disorders
    Jack R Cornelius
    Center for Education and Drug Abuse Research, University of Pittsburgh, 3811 O Hara Street, PAARC Suite, Pittsburgh, PA 15213, USA
    Addict Behav 35:91-4. 2010
    ..This study addresses the effect of PTSD on CUD among teenagers transitioning to young adulthood...
  11. pmc The Violence Proneness Scale of the DUSI-R predicts adverse outcomes associated with substance abuse
    Levent Kirisci
    Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
    Am J Addict 18:173-7. 2009
    ..Prediction accuracy ranged between 62%-83%. These findings suggest that the VPS may be useful for identifying youths who are at high risk for using illicit drugs and commonly associated adverse outcomes...
  12. ncbi request reprint Testosterone levels and sexual maturation predict substance use disorders in adolescent boys: a prospective study
    Maureen D Reynolds
    Center for Education and Drug Abuse Research, University of Pittsburgh School of Pharmacy, Pittsburgh, Pennsylvania 15261, USA
    Biol Psychiatry 61:1223-7. 2007
    ..This investigation determined whether testosterone level and sexual maturation in boys biased development of socially nonnormative behavior culminating in a substance use disorder (SUD)...
  13. pmc Age of alcohol and cannabis use onset mediates the association of transmissible risk in childhood and development of alcohol and cannabis disorders: evidence for common liability
    Levent Kirisci
    Department of Pharmaceutical Sciences, University of Pittsburgh, PA 15213, USA
    Exp Clin Psychopharmacol 21:38-45. 2013
    ..TLI predicts age of first use of alcohol and cannabis that is common to developing both AUD and CUD. The ramifications of these findings for prevention are discussed...
  14. ncbi request reprint Item response theory modeling of substance use: an index based on 10 drug categories
    Levent Kirisci
    Center for Education and Drug Abuse Research, School of Pharmacy, University of Pittsburgh, 707 Salk Hall, Pittsburgh, Pennsylvania 15261, USA
    Psychol Addict Behav 16:290-8. 2002
    ..Finally, this index is a reliable and useful prognostic indicator of the risk for SUD and the medical and psychosocial sequelae of drug consumption...
  15. pmc Quick screen to detect current substance use disorder in adolescents and the likelihood of future disorder
    Levent Kirisci
    Center for Education and Drug Abuse Research, Department of Pharmaceutical Sciences, University of Pittsburgh, School of Pharmacy, Pittsburgh, PA 15213, USA
    Drug Alcohol Depend 128:116-22. 2013
    ..A brief screen requiring 3-4min administration time was developed to detect adolescents qualifying for current substance use disorder (SUD) and those who will subsequently manifest SUD by early adulthood...
  16. ncbi request reprint Pittsburgh Registry of Infant Multiplets (PRIM)
    Melissa Strassberg
    Department of Human Genetics, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
    Twin Res 5:499-501. 2002
    ..g., aggressivity, hyperactivity/impulsivity), as well as language development and other traits (e.g., dental health) are among the research targets...
  17. doi request reprint Modeling the association between sexual maturation, transmissible risk, and peer relationships during childhood and adolescence on development of substance use disorder in young adulthood
    Michelle S Horner
    Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania Center for Education and Drug Abuse Research, Pittsburgh, Pennsylvania
    Am J Addict 22:474-80. 2013
    ..This prospective study investigated pubertal timing and transmissible risk in relation to affiliation with deviant peers on the development of substance use disorder (SUD)...
  18. ncbi request reprint Alcohol and drug use and related disorders: An underrecognized health issue among adolescents and young adults attending sexually transmitted disease clinics
    Robert L Cook
    Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Sex Transm Dis 33:565-70. 2006
    ....
  19. ncbi request reprint Modeling the pathways linking childhood hyperactivity and substance use disorder in young adulthood
    Ralph E Tarter
    Center for Education and Drug Abuse Research, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA 15261, USA
    Psychol Addict Behav 21:266-71. 2007
    ..These results indicate that hyperactivity is a diathesis for both internalizing and externalizing disturbances that, in turn, portend differential expression of psychosocial maladjustment presaging SUD...
  20. ncbi request reprint Childhood neurobehavior disinhibition amplifies the risk of substance use disorder: interaction of parental history and prenatal alcohol exposure
    Kim Chapman
    Department of Pediatrics, University of Pittsburgh Medical Center, Pittsburgh, PA 15261, USA
    J Dev Behav Pediatr 28:219-24. 2007
    ..The extent to which ND predicted SUD outcome 7 to 9 years later was also determined...
  21. ncbi request reprint An application of item response theory to the DSM-III-R criteria for borderline personality disorder
    Ulrike Feske
    Center for Education and Drug Abuse Research, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA 15261, USA
    J Pers Disord 21:418-33. 2007
    ..The general conclusion is that the criteria do represent a coherent syndrome and that further research on the informational value of the individual criteria would be useful...
  22. ncbi request reprint Reciprocal influence of parent discipline and child's behavior on risk for substance use disorder: a nine-year prospective study
    Ada C Mezzich
    School of Pharmacy, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
    Am J Drug Alcohol Abuse 33:851-67. 2007
    ....
  23. ncbi request reprint Social dominance mediates the association of testosterone and neurobehavioral disinhibition with risk for substance use disorder
    Ralph E Tarter
    Department of Pharmaceutical Sciences, University of Pittsburgh, PA 15261, USA
    Psychol Addict Behav 21:462-8. 2007
    ..In addition, SD/NVB mediated the association between ND and SUD. These findings suggest that development of SUD is influenced by androgen-dependent and neurobehavioral processes via a social motivational style characterized by SD/NVB...
  24. doi request reprint Brain activation, response inhibition, and increased risk for substance use disorder
    REBECCA L MCNAMEE
    Department of Pharmaceutical Sciences, University of Pittsburgh, Pennsylvania 15261, USA
    Alcohol Clin Exp Res 32:405-13. 2008
    ..Youth at high risk for developing substance use disorders (SUDs) often exhibit differences which suggest inhibitory impairments when compared to average risk youth...
  25. doi request reprint Peer environment mediates parental history and individual risk in the etiology of cannabis use disorder in boys: a 10-year prospective study
    Ulrike Feske
    Center for Education and Drug Abuse Research CEDAR, School of Pharmacy, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
    Am J Drug Alcohol Abuse 34:307-20. 2008
    ..Peer environment mediated the association between ND and cannabis use and ND and CUD. Maternal and paternal SUD predicted the peer environment. Parental SUD, son's ND, and son's peer environment predicted CUD at age 22 with 84% accuracy...
  26. ncbi request reprint Etiology of adolescent substance abuse: a developmental perspective
    Ralph E Tarter
    Center for Education and Drug Abuse Research, Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA 15261, USA
    Am J Addict 11:171-91. 2002
    ..This discussion examines the etiology of ATOD abuse and SUD from a developmental perspective. The ramifications of a developmental perspective for clinical practice and social policy are also considered...
  27. ncbi request reprint Assessment of risk for substance use disorder consequent to consumption of illegal drugs: psychometric validation of the neurobehavior disinhibition trait
    Ada C Mezzich
    Center for Education and Drug Abuse Research CEDAR, Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, PA 15261, USA
    Psychol Addict Behav 21:508-15. 2007
    ..The ND trait may be useful for detecting youths at high risk for developing SUD and related outcomes...
  28. pmc Delinquency as a mediator of the relation between negative affectivity and adolescent alcohol use disorder
    Gavin D Shoal
    Department of Psychology, University of Kentucky, 115 Kastle Hall, Lexington, KY 40506 0044, USA
    Addict Behav 32:2747-65. 2007
    ..The importance and implications of testing delinquency variables together in the same model are discussed...
  29. ncbi request reprint Predicting adolescent violence: impact of family history, substance use, psychiatric history, and social adjustment
    Ralph E Tarter
    Department of Pharmaceutical Sciences, University of Pittsburgh, PA 15261, USA
    Am J Psychiatry 159:1541-7. 2002
    ..In addition, the authors sought to use this screening instrument, in conjunction with child and parent psychopathology and substance abuse data, to determine the accuracy of violent outcome predictions...
  30. ncbi request reprint Characteristics of men with substance use disorder consequent to illicit drug use: comparison of a random sample and volunteers
    Maureen D Reynolds
    Department of Pharmaceutical Sciences, Center for Education and Drug Abuse Research, School of Pharmacy, University of Pittsburgh, 711 Salk Hall, Pittsburgh, PA 15261, USA
    Drug Alcohol Depend 75:241-51. 2004
    ..It was hypothesized that volunteers would be more self-disclosing and exhibit more severe disturbances compared to randomly recruited subjects...
  31. ncbi request reprint Haplotypes of the monoamine oxidase genes and the risk for substance use disorders
    Michael M Vanyukov
    Center for Education and Drug Abuse Research, Department of Pharmaceutical Sciences, University of Pittsburgh School of Pharmacy, Pittsburgh, Pennsylvania 15261, USA
    Am J Med Genet B Neuropsychiatr Genet 125:120-5. 2004
    ..Overall, our results, albeit not definitive, are consistent with the hypothesis that variants in MAOA account for a small portion of the variance of SUD risk, possibly mediated by liability to early onset behavioral problems...
  32. ncbi request reprint Neurobehavior disinhibition in childhood predisposes boys to substance use disorder by young adulthood: direct and mediated etiologic pathways
    Ralph E Tarter
    Department of Pharmaceutical Sciences, Center for Education and Drug Abuse Research, School of Pharmacy, University of Pittsburgh, 711 Salk Hall, Pittsburgh, PA 15261, USA
    Drug Alcohol Depend 73:121-32. 2004
    ..Evaluations were conducted to determine the context in which neurobehavior disinhibition in relation to parental SUD, parental neglect of the child and child's social maladjustment culminated in a DSM-III-R diagnosis of SUD...
  33. ncbi request reprint Liability to substance use disorders: 2. A measurement approach
    Michael M Vanyukov
    Department of Pharmaceutical Sciences, Center for Education and Drug Abuse Research, University of Pittsburgh, 707 Salk Hall, Pittsburgh, PA 15261, USA
    Neurosci Biobehav Rev 27:517-26. 2003
    ..This method is also applicable to measuring liabilities to other complex disorders, especially those with relatively late onset...
  34. ncbi request reprint Liability to substance use disorders: 1. Common mechanisms and manifestations
    Michael M Vanyukov
    Department of Pharmaceutical Sciences, Center for Education and Drug Abuse Research, University of Pittsburgh, 707 Salk Hall, Pittsburgh, PA 15261, USA
    Neurosci Biobehav Rev 27:507-15. 2003
    ..An accompanying paper describes an approach to the quantitative estimation of this trait...
  35. ncbi request reprint Predictor variables by developmental stages: a center for substance abuse prevention multisite study
    Ralph E Tarter
    Department of Pharmaceutical Sciences, University of Pittsburgh School of Pharmacy, Pennsylvania 15261, USA
    Psychol Addict Behav 16:S3-10. 2002
    ..In this introduction, both the theoretical framework and rationale guiding this cooperative agreement and the key findings are described...
  36. ncbi request reprint Reactive aggression in boys with disruptive behavior disorders: behavior, physiology, and affect
    Daniel A Waschbusch
    Department of Psychology, Dalhousie University, Halifax, Nova Scotia, Canada B3H 4J1
    J Abnorm Child Psychol 30:641-56. 2002
    ..In addition, boys with comorbid ADHD/ODD/CD held a grudge longer than other children. Results suggest that boys with comorbid ADHD/ODD/CD are especially reactive to provocation from their peers...
  37. ncbi request reprint Origins and consequences of child neglect in substance abuse families
    Marija G Dunn
    School of Pharmacy, University of Pittsburgh, 711 Salk Hall, Pittsburgh, PA 15261, USA
    Clin Psychol Rev 22:1063-90. 2002
    ....
  38. ncbi request reprint Relation between cognitive distortions and neurobehavior disinhibition on the development of substance use during adolescence and substance use disorder by young adulthood: a prospective study
    Levent Kirisci
    Center for Education and Drug Abuse Research CEDAR, School of Pharmacy, University of Pittsburgh, 711 Salk Hall, Pittsburgh, PA 15261, USA
    Drug Alcohol Depend 76:125-33. 2004
    ....
  39. ncbi request reprint Impaired oculomotor response inhibition in children of alcoholics: The role of attention deficit hyperactivity disorder
    Miguel E Habeych
    Center for Education and Drug Abuse Research, Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, 711 Salk Hall, Pittsburgh, PA, USA
    Drug Alcohol Depend 82:11-7. 2006
    ..The aim of the project was to determine whether children at high risk for alcohol use disorder (AUD) are impaired at performing oculomotor response inhibition tasks sensitive to detecting prefrontal cortex dysfunction...
  40. ncbi request reprint Direct and mediated associations between P300 amplitude in childhood and substance use disorders outcome in young adulthood
    Miguel E Habeych
    Center for Education and Drug Abuse Research, Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, 711 Salk Hall, Pittsburgh, PA 15261, USA
    Biol Psychiatry 57:76-82. 2005
    ..This investigation had two aims: 1) determine whether P300 amplitude in late childhood is a predictor of SUD outcome by age 19; and 2) evaluate whether neurobehavior disinhibition (ND) mediates this association...
  41. ncbi request reprint Childhood risk categories for adolescent substance involvement: a general liability typology
    Duncan B Clark
    Department of Psychiatry, University of Pittsburgh, 3811 O Hara Street, Pittsburgh, PA 15213, USA
    Drug Alcohol Depend 77:13-21. 2005
    ..The findings indicate that these five risk categories constitute general liability classes for adolescent substance involvement, and may identify homogeneous groups of children requiring distinct preventive interventions...
  42. ncbi request reprint Individual differences in childhood neurobehavior disinhibition predict decision to desist substance use during adolescence and substance use disorder in young adulthood: a prospective study
    Levent Kirisci
    Center for Education and Drug Abuse Research, University of Pittsburgh, PA 15261, USA
    Addict Behav 31:686-96. 2006
    ..The findings indicate that substance abuse prevention would be potentiated by ameliorating childhood neurobehavior disinhibition...
  43. ncbi request reprint Association among parental substance use disorder, p300 amplitude, and neurobehavioral disinhibition in preteen boys at high risk for substance use disorder
    Miguel E Habeych
    Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, PA 16261, USA
    Psychol Addict Behav 19:123-30. 2005
    ..It was concluded that the P300 amplitude does not mediate the association between parental SUD and child's neurobehavioral disinhibition...
  44. ncbi request reprint Borderline personality and substance use in women
    Ulrike Feske
    Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Am J Addict 15:131-7. 2006
    ..Antisocial personality disorder generally yielded larger odds ratios than BPD and emerged as a partial mediator of the relation between BPD and SUD. Histrionic PD was the only other PD that showed meaningful relations with SUD...
  45. ncbi request reprint Application of item response theory to quantify substance use disorder severity
    Levent Kirisci
    Center for Education and Drug Abuse Research, Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, 711 Salk Hall, Pittsburgh, PA 15261, USA
    Addict Behav 31:1035-49. 2006
    ....
  46. ncbi request reprint Overview of workshop on drug abuse and suicidal behavior
    Lynda Erinoff
    Drug Alcohol Depend 76:S3-9. 2004
  47. ncbi request reprint Pittsburgh Registry of Infant Multiplets (PRIM): an update
    Elizabeth A Jenkins
    Department of Human Genetics, University of Pittsburgh, 707 Salk Hall, Pittsburgh, PA 15261, USA
    Twin Res Hum Genet 9:1006-8. 2006
    ..Pilot data on the heritability of minor physical anomalies and neuropsychological characteristics (Continuous Performance Test) are reported...

Research Grants7

  1. COGNITIVE-PSYCHOSOCIAL INTERACTIONS AND ALCOHOLISM RISK
    Ralph Tarter; Fiscal Year: 2003
    ..Furthermore, this project will afford the opportunity to elucidate AUD etiology as the culmination of person- environment interactions. ..