Research Topics
Species | R E TarterSummaryAffiliation: University of Pittsburgh Country: USA Publications
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Publications
Borderline personality and substance use in womenUlrike Feske
Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
Am J Addict 15:131-7. 2006..Antisocial personality disorder generally yielded larger odds ratios than BPD and emerged as a partial mediator of the relation between BPD and SUD. Histrionic PD was the only other PD that showed meaningful relations with SUD...
Relation among HPA and HPG neuroendocrine systems, transmissible risk and neighborhood quality on development of substance use disorder: Results of a 10-year prospective studyRalph E Tarter
Center for Education and Drug Abuse Research, Department of Pharmaceutical Sciences, University of Pittsburgh, 3520 Forbes Avenue, Parkvale Annex, 2nd Floor, Pittsburgh, PA 15213, United States Electronic address
Drug Alcohol Depend 127:226-31. 2013....
Does the "gateway" sequence increase prediction of cannabis use disorder development beyond deviant socialization? Implications for prevention practice and policyRalph E Tarter
Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, PA 15213, United States
Drug Alcohol Depend 123:S72-8. 2012..e., consuming legal drugs before cannabis, or the reverse) increases accuracy of prediction of cannabis use disorder...
Neurobehavior disinhibition in childhood predicts suicide potential and substance use disorder by young adulthoodR E Tarter
Center for Education and Drug Abuse Research, Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, 711 Salk Hall, Pittsburgh, PA 15261, USA
Drug Alcohol Depend 76:S45-52. 2004..These results are discussed within a neurobehavioral framework in which prefrontal cortex dysfunction is hypothesized to underlie the risk for these two outcomes...
Predictor variables by developmental stages: a center for substance abuse prevention multisite studyRalph E Tarter
Department of Pharmaceutical Sciences, University of Pittsburgh School of Pharmacy, Pennsylvania 15261, USA
Psychol Addict Behav 16:S3-10. 2002..In this introduction, both the theoretical framework and rationale guiding this cooperative agreement and the key findings are described...
Modeling the pathways linking childhood hyperactivity and substance use disorder in young adulthoodRalph E Tarter
Center for Education and Drug Abuse Research, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA 15261, USA
Psychol Addict Behav 21:266-71. 2007..These results indicate that hyperactivity is a diathesis for both internalizing and externalizing disturbances that, in turn, portend differential expression of psychosocial maladjustment presaging SUD...
Neurobehavior disinhibition in childhood predisposes boys to substance use disorder by young adulthood: direct and mediated etiologic pathwaysRalph E Tarter
Department of Pharmaceutical Sciences, Center for Education and Drug Abuse Research, School of Pharmacy, University of Pittsburgh, 711 Salk Hall, Pittsburgh, PA 15261, USA
Drug Alcohol Depend 73:121-32. 2004..Evaluations were conducted to determine the context in which neurobehavior disinhibition in relation to parental SUD, parental neglect of the child and child's social maladjustment culminated in a DSM-III-R diagnosis of SUD...
Etiology of adolescent substance abuse: a developmental perspectiveRalph E Tarter
Center for Education and Drug Abuse Research, Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA 15261, USA
Am J Addict 11:171-91. 2002..This discussion examines the etiology of ATOD abuse and SUD from a developmental perspective. The ramifications of a developmental perspective for clinical practice and social policy are also considered...
Social dominance mediates the association of testosterone and neurobehavioral disinhibition with risk for substance use disorderRalph E Tarter
Department of Pharmaceutical Sciences, University of Pittsburgh, PA 15261, USA
Psychol Addict Behav 21:462-8. 2007..In addition, SD/NVB mediated the association between ND and SUD. These findings suggest that development of SUD is influenced by androgen-dependent and neurobehavioral processes via a social motivational style characterized by SD/NVB...
Prospective study of the association between abandoned dwellings and testosterone level on the development of behaviors leading to cannabis use disorder in boysRalph E Tarter
Department of Pharmaceutical Sciences, Center for Education and Drug Abuse Research, University of Pittsburgh, School of Pharmacy, Pittsburgh, PA 15261, USA
Biol Psychiatry 65:116-21. 2009..It was theorized that adverse neighborhood correlates with testosterone level that in turn potentiates behaviors predisposing to cannabis consumption and subsequently diagnosis of cannabis use disorder...
Deviant socialization mediates transmissible and contextual risk on cannabis use disorder development: a prospective studyRalph E Tarter
University of Pittsburgh, Department of Pharmaceutical Sciences, Pittsburgh, PA 15261, USA
Addiction 106:1301-8. 2011..This study examined the contribution of transmissible risk, in conjunction with family and peer contextual factors during childhood and adolescence, on the development of cannabis use disorder in adulthood...
Predictors of marijuana use in adolescents before and after licit drug use: examination of the gateway hypothesisRalph E Tarter
Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, PA 15261, USA
Am J Psychiatry 163:2134-40. 2006..They also evaluated the accuracy of the "gateway sequence" (illicit drug use following licit drugs) for predicting a diagnosis of substance use disorder...
An association between a microsatellite polymorphism at the DRD5 gene and the liability to substance abuse: pilot studyM M Vanyukov
Center for Education and Drug Abuse Research CEDAR, University of Pittsburgh, Pennsylvania 15213, USA
Behav Genet 28:75-82. 1998..The data suggest that the DRD5 locus is involved in the variation and sex dimorphism of substance abuse liability...
Predicting adolescent violence: impact of family history, substance use, psychiatric history, and social adjustmentRalph E Tarter
Department of Pharmaceutical Sciences, University of Pittsburgh, PA 15261, USA
Am J Psychiatry 159:1541-7. 2002....
Childhood neurobehavior disinhibition amplifies the risk of substance use disorder: interaction of parental history and prenatal alcohol exposureKim Chapman
Department of Pediatrics, University of Pittsburgh Medical Center, Pittsburgh, PA 15261, USA
J Dev Behav Pediatr 28:219-24. 2007..The extent to which ND predicted SUD outcome 7 to 9 years later was also determined...
Impact of parental substance use disorder and child neglect severity on substance use involvement in male offspringL Kirisci
Department of Pharmaceutical Sciences, University of Pittsburgh, Pennsylvania 15261, USA
Prev Sci 2:241-55. 2001....
Mating assortment and the liability to substance abuseM M Vanyukov
Center for Education and Drug Abuse Research CEDAR, University of Pittsburgh School of Medicine, PA 15213, USA
Drug Alcohol Depend 42:1-10. 1996..This paper reviews the theoretical and empirical literature on mechanisms related to mate resemblance for the liability to substance abuse, sources and consequences of such resemblance, and suggests directions for further research...
Genetic studies of substance abuseM M Vanyukov
Center for Education and Drug Abuse Research, University of Pittsburgh, 3811 O Hara Street, PA 15213, USA
Drug Alcohol Depend 59:101-23. 2000..This paper reviews the concepts, methods and results pertaining to genetic investigation of substance abuse...
Pittsburgh Registry of Infant Multiplets (PRIM): an updateElizabeth A Jenkins
Department of Human Genetics, University of Pittsburgh, 707 Salk Hall, Pittsburgh, PA 15261, USA
Twin Res Hum Genet 9:1006-8. 2006..Pilot data on the heritability of minor physical anomalies and neuropsychological characteristics (Continuous Performance Test) are reported...
Executive cognitive functioning, temperament, and antisocial behavior in conduct-disordered adolescent femalesP R Giancola
Department of Psychiatry, University of Pittsburgh School of Medicine, Pennsylvania 15213 2593, USA
J Abnorm Psychol 107:629-41. 1998..Last, ECF mediated the relation between difficult temperament and aggressive ASB...
Origins and consequences of child neglect in substance abuse familiesMarija G Dunn
School of Pharmacy, University of Pittsburgh, 711 Salk Hall, Pittsburgh, PA 15261, USA
Clin Psychol Rev 22:1063-90. 2002....
An application of item response theory to the DSM-III-R criteria for borderline personality disorderUlrike Feske
Center for Education and Drug Abuse Research, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA 15261, USA
J Pers Disord 21:418-33. 2007..The general conclusion is that the criteria do represent a coherent syndrome and that further research on the informational value of the individual criteria would be useful...
Reciprocal influence of parent discipline and child's behavior on risk for substance use disorder: a nine-year prospective studyAda C Mezzich
School of Pharmacy, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
Am J Drug Alcohol Abuse 33:851-67. 2007....
Peer environment mediates parental history and individual risk in the etiology of cannabis use disorder in boys: a 10-year prospective studyUlrike Feske
Center for Education and Drug Abuse Research CEDAR, School of Pharmacy, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
Am J Drug Alcohol Abuse 34:307-20. 2008..Peer environment mediated the association between ND and cannabis use and ND and CUD. Maternal and paternal SUD predicted the peer environment. Parental SUD, son's ND, and son's peer environment predicted CUD at age 22 with 84% accuracy...
Neurobehavior disinhibition, parental substance use disorder, neighborhood quality and development of cannabis use disorder in boysTy A Ridenour
Center for Education and Drug Abuse Research, University of Pittsburgh, 711 Salk Hall, Pittsburgh, PA 15261, USA
Drug Alcohol Depend 102:71-7. 2009..The implications of this pattern of association between parental SUD, neighborhood context and individual risk for SUD for improving prevention are discussed...
Association among parental substance use disorder, p300 amplitude, and neurobehavioral disinhibition in preteen boys at high risk for substance use disorderMiguel E Habeych
Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, PA 16261, USA
Psychol Addict Behav 19:123-30. 2005..It was concluded that the P300 amplitude does not mediate the association between parental SUD and child's neurobehavioral disinhibition...
Prospective study of the association between neurobehavior disinhibition and peer environment on illegal drug use in boys and girlsLevent Kirisci
School of Pharmacy, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
Am J Drug Alcohol Abuse 35:145-50. 2009..Objectives: Male and female children and adolescents were compared to determine the relative influence of individual susceptibility (neurobehavior disinhibition or ND) and social environment (deviancy in peers) on use of illegal drugs...
Individual and environmental correlates and predictors of early adherence and outcomes after liver transplantationCarol S Stilley
University of Pittsburgh, Pittsburgh, Pennsylvania, USA
Prog Transplant 20:58-66; quiz 67. 2010..Yet, in other transplant recipients, nonadherent behavior is directly related to the leading causes of morbidity and mortality in liver transplant recipients...
Liver transplant recipients: individual, social, and environmental resourcesCarol S Stilley
University of Pittsburgh, PA, USA
Prog Transplant 20:68-74. 2010....
Characteristics of men with substance use disorder consequent to illicit drug use: comparison of a random sample and volunteersMaureen D Reynolds
Department of Pharmaceutical Sciences, Center for Education and Drug Abuse Research, School of Pharmacy, University of Pittsburgh, 711 Salk Hall, Pittsburgh, PA 15261, USA
Drug Alcohol Depend 75:241-51. 2004..It was hypothesized that volunteers would be more self-disclosing and exhibit more severe disturbances compared to randomly recruited subjects...
Measurement of the risk for substance use disorders: phenotypic and genetic analysis of an index of common liabilityMichael M Vanyukov
Center for Education and Drug Abuse Research, Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, 711 Salk Hall, Pittsburgh, PA 15261, USA
Behav Genet 39:233-44. 2009..The data suggest a high heritability of the index in males. The results suggest applicability of the method for genetic and other etiology-related research, and for evaluation of individual risk...
Childhood risk categories for adolescent substance involvement: a general liability typologyDuncan B Clark
Department of Psychiatry, University of Pittsburgh, 3811 O Hara Street, Pittsburgh, PA 15213, USA
Drug Alcohol Depend 77:13-21. 2005..The findings indicate that these five risk categories constitute general liability classes for adolescent substance involvement, and may identify homogeneous groups of children requiring distinct preventive interventions...
Individual differences in childhood neurobehavior disinhibition predict decision to desist substance use during adolescence and substance use disorder in young adulthood: a prospective studyLevent Kirisci
Center for Education and Drug Abuse Research, University of Pittsburgh, PA 15261, USA
Addict Behav 31:686-96. 2006..The findings indicate that substance abuse prevention would be potentiated by ameliorating childhood neurobehavior disinhibition...
Liability to substance use disorders: 2. A measurement approachMichael M Vanyukov
Department of Pharmaceutical Sciences, Center for Education and Drug Abuse Research, University of Pittsburgh, 707 Salk Hall, Pittsburgh, PA 15261, USA
Neurosci Biobehav Rev 27:517-26. 2003..This method is also applicable to measuring liabilities to other complex disorders, especially those with relatively late onset...
Haplotypes of the monoamine oxidase genes and the risk for substance use disordersMichael M Vanyukov
Center for Education and Drug Abuse Research, Department of Pharmaceutical Sciences, University of Pittsburgh School of Pharmacy, Pittsburgh, Pennsylvania 15261, USA
Am J Med Genet B Neuropsychiatr Genet 125:120-5. 2004..Overall, our results, albeit not definitive, are consistent with the hypothesis that variants in MAOA account for a small portion of the variance of SUD risk, possibly mediated by liability to early onset behavioral problems...
Impaired oculomotor response inhibition in children of alcoholics: The role of attention deficit hyperactivity disorderMiguel E Habeych
Center for Education and Drug Abuse Research, Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, 711 Salk Hall, Pittsburgh, PA, USA
Drug Alcohol Depend 82:11-7. 2006..The aim of the project was to determine whether children at high risk for alcohol use disorder (AUD) are impaired at performing oculomotor response inhibition tasks sensitive to detecting prefrontal cortex dysfunction...
Direct and mediated associations between P300 amplitude in childhood and substance use disorders outcome in young adulthoodMiguel E Habeych
Center for Education and Drug Abuse Research, Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, 711 Salk Hall, Pittsburgh, PA 15261, USA
Biol Psychiatry 57:76-82. 2005..This investigation had two aims: 1) determine whether P300 amplitude in late childhood is a predictor of SUD outcome by age 19; and 2) evaluate whether neurobehavior disinhibition (ND) mediates this association...
Liability to substance use disorders: 1. Common mechanisms and manifestationsMichael M Vanyukov
Department of Pharmaceutical Sciences, Center for Education and Drug Abuse Research, University of Pittsburgh, 707 Salk Hall, Pittsburgh, PA 15261, USA
Neurosci Biobehav Rev 27:507-15. 2003..An accompanying paper describes an approach to the quantitative estimation of this trait...
Application of item response theory to quantify substance use disorder severityLevent Kirisci
Center for Education and Drug Abuse Research, Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, 711 Salk Hall, Pittsburgh, PA 15261, USA
Addict Behav 31:1035-49. 2006....
Neurobehavioral disinhibition in childhood predicts early age at onset of substance use disorderRalph E Tarter
University of Pittsburgh, Department of Pharmaceutical Sciences, Pittsburgh, PA 15261, USA
Am J Psychiatry 160:1078-85. 2003....
Relation between cognitive distortions and neurobehavior disinhibition on the development of substance use during adolescence and substance use disorder by young adulthood: a prospective studyLevent Kirisci
Center for Education and Drug Abuse Research CEDAR, School of Pharmacy, University of Pittsburgh, 711 Salk Hall, Pittsburgh, PA 15261, USA
Drug Alcohol Depend 76:125-33. 2004....
Assessment of risk for substance use disorder consequent to consumption of illegal drugs: psychometric validation of the neurobehavior disinhibition traitAda C Mezzich
Center for Education and Drug Abuse Research CEDAR, Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, PA 15261, USA
Psychol Addict Behav 21:508-15. 2007..The ND trait may be useful for detecting youths at high risk for developing SUD and related outcomes...
Brain activation, response inhibition, and increased risk for substance use disorderREBECCA L MCNAMEE
Department of Pharmaceutical Sciences, University of Pittsburgh, Pennsylvania 15261, USA
Alcohol Clin Exp Res 32:405-13. 2008..Youth at high risk for developing substance use disorders (SUDs) often exhibit differences which suggest inhibitory impairments when compared to average risk youth...
Concordance between verbal report and urine screen of recent marijuana use in adolescentsI H Akinci
Center for Education and Drug Abuse Research, School of Pharmacy, University of Pittsburgh, PA 15261, USA
Addict Behav 26:613-9. 2001..In total, 13% of the participants (26/200) inaccurately reported recent cannabis use. These results underscore the need for caution in interpreting the results of self-report methods documenting the prevalence of drug use among youth...
Antisociality, substance dependence, and the DRD5 gene: a preliminary studyM M Vanyukov
Center for Education and Drug Abuse Research CEDAR, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
Am J Med Genet 96:654-8. 2000..The data suggest involvement of the DRD5 locus in the variation and sexual dimorphism of SD liability and antisociality and in the developmental continuity of antisociality...
Reactive aggression in boys with disruptive behavior disorders: behavior, physiology, and affectDaniel A Waschbusch
Department of Psychology, Dalhousie University, Halifax, Nova Scotia, Canada B3H 4J1
J Abnorm Child Psychol 30:641-56. 2002..In addition, boys with comorbid ADHD/ODD/CD held a grudge longer than other children. Results suggest that boys with comorbid ADHD/ODD/CD are especially reactive to provocation from their peers...
Delinquency as a mediator of the relation between negative affectivity and adolescent alcohol use disorderGavin D Shoal
Department of Psychology, University of Kentucky, 115 Kastle Hall, Lexington, KY 40506 0044, USA
Addict Behav 32:2747-65. 2007..The importance and implications of testing delinquency variables together in the same model are discussed...
Overview of workshop on drug abuse and suicidal behaviorLynda Erinoff
Drug Alcohol Depend 76:S3-9. 2004
