Weihong Tang

Summary

Affiliation: University of Minnesota
Country: USA

Publications

  1. doi request reprint A genome-wide association study for venous thromboembolism: the extended cohorts for heart and aging research in genomic epidemiology (CHARGE) consortium
    Weihong Tang
    Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, Minnesota 55454, USA
    Genet Epidemiol 37:512-21. 2013
  2. pmc Genetic associations for activated partial thromboplastin time and prothrombin time, their gene expression profiles, and risk of coronary artery disease
    Weihong Tang
    Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, 55454, USA
    Am J Hum Genet 91:152-62. 2012
  3. pmc Do inflammation and procoagulation biomarkers contribute to the metabolic syndrome cluster?
    Aldi T Kraja
    Division of Statistical Genomics, Washington University School of Medicine, Saint Louis, MO, USA
    Nutr Metab (Lond) 4:28. 2007
  4. pmc QTLs of factors of the metabolic syndrome and echocardiographic phenotypes: the hypertension genetic epidemiology network study
    Aldi T Kraja
    Division of Statistical Genomics, Washington University School of Medicine, Saint Louis, MO, USA
    BMC Med Genet 9:103. 2008
  5. pmc Identification of a pleiotropic locus on chromosome 7q for a composite left ventricular wall thickness factor and body mass index: the HyperGEN Study
    Weihong Tang
    Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN, USA
    BMC Med Genet 10:40. 2009
  6. pmc Association of sICAM-1 and MCP-1 with coronary artery calcification in families enriched for coronary heart disease or hypertension: the NHLBI Family Heart Study
    Weihong Tang
    Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN, USA
    BMC Cardiovasc Disord 7:30. 2007
  7. pmc Associations of lipoprotein lipase gene polymorphisms with longitudinal plasma lipid trends in young adults: The Coronary Artery Risk Development in Young Adults (CARDIA) study
    Weihong Tang
    University of Minnesota, Minneapolis, USA
    Circ Cardiovasc Genet 3:179-86. 2010
  8. pmc Genome-wide association study identifies novel loci for plasma levels of protein C: the ARIC study
    Weihong Tang
    Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN 55454, USA
    Blood 116:5032-6. 2010
  9. pmc Genome-wide association study identifies single-nucleotide polymorphism in KCNB1 associated with left ventricular mass in humans: the HyperGEN Study
    Donna K Arnett
    Department of Epidemiology, School of Public Health, University of Alabama at Birmingham, 1530 3rd Avenue South, Birmingham AL 35294 0022, USA
    BMC Med Genet 10:43. 2009
  10. ncbi request reprint The Arg16Gly polymorphism of the beta2-adrenergic receptor and left ventricular systolic function
    Weihong Tang
    Division of Epidemiology, University of Minnesota, Minneapolis, Minnesota 55454, USA
    Am J Hypertens 16:945-51. 2003

Detail Information

Publications32

  1. doi request reprint A genome-wide association study for venous thromboembolism: the extended cohorts for heart and aging research in genomic epidemiology (CHARGE) consortium
    Weihong Tang
    Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, Minnesota 55454, USA
    Genet Epidemiol 37:512-21. 2013
    ..Future studies are warranted to better characterize the associations with F11 and FGG and to replicate the new candidate associations...
  2. pmc Genetic associations for activated partial thromboplastin time and prothrombin time, their gene expression profiles, and risk of coronary artery disease
    Weihong Tang
    Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, 55454, USA
    Am J Hum Genet 91:152-62. 2012
    ..In summary, eight genetic loci that account for ∼29% of the variance in aPTT and two loci that account for ∼14% of the variance in PT were detected and supported by functional data...
  3. pmc Do inflammation and procoagulation biomarkers contribute to the metabolic syndrome cluster?
    Aldi T Kraja
    Division of Statistical Genomics, Washington University School of Medicine, Saint Louis, MO, USA
    Nutr Metab (Lond) 4:28. 2007
    ..However, the relationship of inflammatory biomarkers to MetS is not clear...
  4. pmc QTLs of factors of the metabolic syndrome and echocardiographic phenotypes: the hypertension genetic epidemiology network study
    Aldi T Kraja
    Division of Statistical Genomics, Washington University School of Medicine, Saint Louis, MO, USA
    BMC Med Genet 9:103. 2008
    ....
  5. pmc Identification of a pleiotropic locus on chromosome 7q for a composite left ventricular wall thickness factor and body mass index: the HyperGEN Study
    Weihong Tang
    Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN, USA
    BMC Med Genet 10:40. 2009
    ....
  6. pmc Association of sICAM-1 and MCP-1 with coronary artery calcification in families enriched for coronary heart disease or hypertension: the NHLBI Family Heart Study
    Weihong Tang
    Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN, USA
    BMC Cardiovasc Disord 7:30. 2007
    ..In the follow-up exam of the NHLBI Family Heart Study, we evaluated whether plasma levels of sICAM-1 and MCP-1 were associated with coronary artery calcification (CAC), a measure of the burden of coronary atherosclerosis...
  7. pmc Associations of lipoprotein lipase gene polymorphisms with longitudinal plasma lipid trends in young adults: The Coronary Artery Risk Development in Young Adults (CARDIA) study
    Weihong Tang
    University of Minnesota, Minneapolis, USA
    Circ Cardiovasc Genet 3:179-86. 2010
    ..However, the influences of the lipoprotein lipase SNPs on longitudinal changes of these lipids have not been systematically examined...
  8. pmc Genome-wide association study identifies novel loci for plasma levels of protein C: the ARIC study
    Weihong Tang
    Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN 55454, USA
    Blood 116:5032-6. 2010
    ..In summary, this first genome-wide scan for circulating protein C concentration identified both new and known loci in the general population. These findings may improve the understanding of physiologic mechanisms in protein C regulation...
  9. pmc Genome-wide association study identifies single-nucleotide polymorphism in KCNB1 associated with left ventricular mass in humans: the HyperGEN Study
    Donna K Arnett
    Department of Epidemiology, School of Public Health, University of Alabama at Birmingham, 1530 3rd Avenue South, Birmingham AL 35294 0022, USA
    BMC Med Genet 10:43. 2009
    ..Eleven of 12 promising (Q < 0.8) single-nucleotide polymorphisms (SNPs) from the genome-wide study were successfully genotyped using quantitative real time PCR in a validation study...
  10. ncbi request reprint The Arg16Gly polymorphism of the beta2-adrenergic receptor and left ventricular systolic function
    Weihong Tang
    Division of Epidemiology, University of Minnesota, Minneapolis, Minnesota 55454, USA
    Am J Hypertens 16:945-51. 2003
    ..This study examined the association of the beta2-AR Arg16Gly polymorphism with left ventricular (LV) systolic function in a biethnic population-based sample...
  11. ncbi request reprint Racial differences in the association of coronary calcified plaque with left ventricular hypertrophy: the National Heart, Lung, and Blood Institute Family Heart Study and Hypertension Genetic Epidemiology Network
    Weihong Tang
    Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, Minnesota, USA
    Am J Cardiol 97:1441-8. 2006
    ....
  12. ncbi request reprint Familial clustering for features of the metabolic syndrome: the National Heart, Lung, and Blood Institute (NHLBI) Family Heart Study
    Weihong Tang
    Division of Epidemiology and Community Health, University of Minnesota, 1300 South Second St, Suite 300, Minneapolis, MN 55454, USA
    Diabetes Care 29:631-6. 2006
    ..We present a bivariate genetic analysis of MetS-related traits including both traditional and novel risk factors...
  13. pmc Effect of 9p21 genetic variation on coronary heart disease is not modified by other risk markers. The Atherosclerosis Risk in Communities (ARIC) Study
    Aaron R Folsom
    Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, 1300 South 2nd Street, Suite 300, Minneapolis, MN 55454, USA
    Atherosclerosis 224:435-9. 2012
    ..To determine whether the 9p21 SNP association with coronary heart disease is modified by other classical or novel risk markers...
  14. ncbi request reprint Identification of a novel 5-base pair deletion in calcineurin B (PPP3R1) promoter region and its association with left ventricular hypertrophy
    Weihong Tang
    Division of Epidemiology, University of Minnesota, Minneapolis, Minnesota, USA
    Am Heart J 150:845-51. 2005
    ..Calcineurin B (CnB) is a regulatory subunit of calcineurin and is important for the phosphatase activity...
  15. ncbi request reprint Sibling resemblance for left ventricular structure, contractility, and diastolic filling
    Weihong Tang
    Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis, USA
    Hypertension 40:233-8. 2002
    ..These data have potential importance in understanding heritability of LV diastolic function in hypertension...
  16. pmc Relation of lipid gene scores to longitudinal trends in lipid levels and incidence of abnormal lipid levels among individuals of European ancestry: the Atherosclerosis Risk in Communities (ARIC) study
    Pamela L Lutsey
    Division of Epidemiology and Community Health, University of Minnesota, 1300 S 2nd Street, Minneapolis, MN 55454, USA
    Circ Cardiovasc Genet 5:73-80. 2012
    ..We tested the hypothesis that persons with an unfavorable lipid gene profile would experience a greater increase in lipid levels and a higher incidence of abnormal lipid levels relative to those with more-favorable lipid gene profiles...
  17. doi request reprint Associations of genetic polymorphisms of arachidonate 5-lipoxygenase-activating protein with risk of coronary artery disease in a European-American population
    Alexander K Tsai
    Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN 55455, USA
    Atherosclerosis 207:487-91. 2009
    ..To examine whether genetic polymorphisms in the 5-lipoxygenase activating protein (ALOX5AP) confer an increased risk to angiographically proven coronary artery disease (CAD) in a case-control study of a Midwestern population in the US...
  18. pmc Novel genetic variants contributing to left ventricular hypertrophy: the HyperGEN study
    Donna K Arnett
    Department of Epidemiology, School of Public Health, University of Alabama at Birmingham, 1665 University Boulevard, Birmingham, AL, USA
    J Hypertens 27:1585-93. 2009
    ..To identify genes contributing to variation in echocardiographic left ventricular mass and related traits using linkage and linkage disequilibrium analysis in sibships ascertained on hypertension...
  19. ncbi request reprint Linkage of left ventricular early diastolic peak filling velocity to chromosome 5 in hypertensive African Americans: the HyperGEN echocardiography study
    Weihong Tang
    Department of Epidemiology, University of Minnesota, Minneapolis 55454, USA
    Am J Hypertens 15:621-7. 2002
    ..The aim of this study was to identify chromosomal regions contributing to variation of LV transmitral early and late peak filling velocities (E and A velocities), Doppler echocardiographic measures of LV diastolic filling...
  20. ncbi request reprint Genome-wide linkage scans for loci affecting total cholesterol, HDL-C, and triglycerides: the Family Blood Pressure Program
    Suzette J Bielinski
    University of Minnesota, Division of Epidemiology and Community Health, West Bank Office Building Suite 300, 1300 South 2nd Street, Minneapolis, MN 55454, USA
    Hum Genet 120:371-80. 2006
    ..The identification of these loci affecting lipid phenotypes and the apparent congruence with previous linkage results provides increased support that these regions contain genes influencing lipid levels...
  21. pmc Vitamin D intake is inversely related to risk of developing metabolic syndrome in African American and white men and women over 20 y: the Coronary Artery Risk Development in Young Adults study
    Grace J Fung
    Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, MN 55454, USA
    Am J Clin Nutr 96:24-9. 2012
    ..Vitamin D intake may play a key role in the prevention of cardiovascular disease...
  22. ncbi request reprint Associations between angiotensinogen gene variants and left ventricular mass and function in the HyperGEN study
    Weihong Tang
    Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis 55454, USA
    Am Heart J 143:854-60. 2002
    ..We investigated whether 2 tightly linked polymorphisms of angiotensinogen gene, M235T and G-6A, are associated with LV mass and function in a large population-based sample, composed mostly of patients with hypertension...
  23. ncbi request reprint Linkage analysis of a composite factor for the multiple metabolic syndrome: the National Heart, Lung, and Blood Institute Family Heart Study
    Weihong Tang
    Division of Epidemiology, University of Minnesota, Minneapolis 55454, USA
    Diabetes 52:2840-7. 2003
    ..34 at 240 cM. Suggestive linkage was also observed for regions on chromosomes 7, 12, 14, and 15. In summary, a genomic region on chromosome 2 may contain a pleiotropic locus contributing to the clustering of MMS-related phenotypes...
  24. ncbi request reprint Interarm differences in seated systolic and diastolic blood pressure: the Hypertension Genetic Epidemiology Network study
    Donna K Arnett
    University of Alabama at Birmingham, School of Public Health, Department of Epidemiology, Birmingham, Alabama 55294 0022, USA
    J Hypertens 23:1141-7. 2005
    ..To examine whether blood pressure (BP) differs between arms in hypertensive siblings and randomly selected volunteers, and whether this difference is explained by cardiovascular risk factors...
  25. pmc Hemostatic markers are associated with the risk and prognosis of atrial fibrillation: the ARIC study
    Alvaro Alonso
    Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN 55454, USA
    Int J Cardiol 155:217-22. 2012
    ..Various hemostatic markers are associated with the risk of cardiovascular disease; however, limited information exists on their relationship with the occurrence and prognosis of atrial fibrillation (AF)...
  26. pmc Longer legs are associated with greater risk of incident venous thromboembolism independent of total body height. The Longitudinal Study of Thromboembolism Etiology (LITE)
    Pamela L Lutsey
    Division of Epidemiology and Community Health, Univ of Minnesota, Minneapolis, Minnesota, USA
    Thromb Haemost 106:113-20. 2011
    ..It remains to be established whether this finding is due to greater venous surface area, a larger number of venous valves, or greater hydrostatic pressure among individuals with longer legs...
  27. pmc Factor relationships of metabolic syndrome and echocardiographic phenotypes in the HyperGEN study
    Pinchia Huang
    Division of Biostatistics, Washington University School of Medicine, Saint Louis, MO 63110, USA
    J Hypertens 26:1360-6. 2008
    ..Metabolic syndrome and its risk factors are predictors of cardiovascular events. Metabolic syndrome is also directly associated with echocardiographic phenotypes...
  28. ncbi request reprint Genome-wide linkage mapping for valve calcification susceptibility loci in hypertensive sibships: the Hypertension Genetic Epidemiology Network Study
    Jonathan N Bella
    Weill Medical College, Cornell University, New York, NY, USA
    Hypertension 49:453-60. 2007
    ..1-q22.3 and suggestive linkage to chromosome 19p13.11-p11 and identifies several other promising genomic regions that may contain specific susceptibility loci for valve calcification...
  29. ncbi request reprint Assessment of the interaction of heritability of volume load and left ventricular mass: the HyperGEN offspring study
    Giovanni de Simone
    Weill Medical College of Cornell University, New York, NY, USA
    J Hypertens 25:1397-402. 2007
    ..Left ventricular mass (LVM) is more closely associated with volume load than pressure load. We assessed whether part of the genetic heritability of LVM can be explained by stroke volume (SV) inheritance...
  30. ncbi request reprint Dietary linolenic acid and fasting glucose and insulin: the National Heart, Lung, and Blood Institute Family Heart Study
    Luc Djousse
    Division of Aging, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02120, USA
    Obesity (Silver Spring) 14:295-300. 2006
    ..To assess whether dietary linolenic acid is associated with fasting insulin and glucose...
  31. ncbi request reprint Re: "(Mis)use of factor analysis in the study of insulin resistance syndrome"
    Weihong Tang
    Am J Epidemiol 162:921-2; author reply 923. 2005
  32. doi request reprint Relation of albuminuria to left ventricular mass (from the HyperGEN Study)
    Luc Djousse
    Division of Aging, Department of Medicine, Brigham and Women s Hospital, Boston, Massachusetts, USA
    Am J Cardiol 101:212-6. 2008
    ..In conclusion, these results suggest that albuminuria is positively associated with LV mass in normotensive subjects as it is in hypertensive subjects...