Detail Information
Publications
A role for NF-kappaB essential modifier/IkappaB kinase-gamma (NEMO/IKKgamma) ubiquitination in the activation of the IkappaB kinase complex by tumor necrosis factor-alphaEric D Tang
Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA
J Biol Chem 278:37297-305. 2003..Also, defective NEMO ubiquitination may be responsible for the impaired cellular NF-kappaB signaling found in patients with HED-ID...
Roles for homotypic interactions and transautophosphorylation in IkappaB kinase beta IKKbeta) activation [corrected]Eric D Tang
Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA
J Biol Chem 278:38566-70. 2003..Our findings support a model whereby ligand-induced homotypic interactions between IKKbeta molecules result in IKKbeta phosphorylation and consequently IKK activation...
