Daiya Takai

Summary

Affiliation: University of Southern California
Country: USA

Publications

  1. ncbi Comprehensive analysis of CpG islands in human chromosomes 21 and 22
    Daiya Takai
    Department of Biochemistry and Molecular Biology, University of Southern California Norris Comprehensive Cancer Center, Keck School of Medicine of the University of Southern California, Los Angeles, CA 90033, USA
    Proc Natl Acad Sci U S A 99:3740-5. 2002
  2. ncbi Distinct localization of histone H3 acetylation and H3-K4 methylation to the transcription start sites in the human genome
    Gangning Liang
    Department of Urology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, 1441 Eastlake Avenue, MS 8302L, Los Angeles, CA 90089 9181
    Proc Natl Acad Sci U S A 101:7357-62. 2004
  3. ncbi Origins of bidirectional promoters: computational analyses of intergenic distance in the human genome
    Daiya Takai
    Department of Biochemistry and Molecular Biology, USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, USA
    Mol Biol Evol 21:463-7. 2004
  4. ncbi Role of nucleosomal occupancy in the epigenetic silencing of the MLH1 CpG island
    Joy C Lin
    Department of Urology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089, USA
    Cancer Cell 12:432-44. 2007
  5. ncbi The CpG island searcher: a new WWW resource
    Daiya Takai
    Department of Biochemistry and Molecular Biology, USC Norris Comprehensive Cancer Center, Keck School of Medicine of the University of Southern California, Los Angeles, USA
    In Silico Biol 3:235-40. 2003
  6. ncbi Establishment of conditional vectors for hairpin siRNA knockdowns
    Shiro Matsukura
    Department of Biochemistry and Molecular Biology, USC/Norris Comprehensive Cancer Center, Keck School of Medicine of the University of Southern California, 1441 Eastlake Avenue, Los Angeles, CA 90033, USA
    Nucleic Acids Res 31:e77. 2003
  7. ncbi Methylation-sensitive representational difference analysis and its application to cancer research
    Atsushi Kaneda
    Carcinogenesis Division, National Cancer Center Research Institute, Tokyo 104-0045, Japan
    Ann N Y Acad Sci 983:131-41. 2003
  8. ncbi Cryopreservation does not alter the allogenicity and development of vasculopathy in post-transplant rat aortas
    Aya Saito
    Department of Cardiothoracic Surgery, Graduate School of Medicine, The University of Tokyo, Japan
    Cryobiology 52:251-60. 2006
  9. ncbi The induction of H3K9 methylation by PIWIL4 at the p16Ink4a locus
    Keiki Sugimoto
    Department of Respiratory Medicine, The University of Tokyo Hospital, Tokyo, Japan
    Biochem Biophys Res Commun 359:497-502. 2007

Collaborators

  • Peter A Jones
  • T Ushijima
  • GANGNING NONE LIANG
  • Aya Saito
  • Keiki Sugimoto
  • Joy C Lin
  • Atsushi Kaneda
  • Shiro Matsukura
  • Hidenori Kage
  • ShinWu Jeong
  • Naomi Aki
  • Takahide Nagase
  • Merhnaz Fatemi
  • Atsushi Sano
  • Hiroshi Kitagawa
  • Yutaka Yatomi
  • Einav Nili Gal-Yam
  • Yvonne C Tsai
  • Gerda Egger
  • Nobuya Ohishi
  • Eriko Okochi
  • Michio Kaminishi

Detail Information

Publications9

  1. ncbi Comprehensive analysis of CpG islands in human chromosomes 21 and 22
    Daiya Takai
    Department of Biochemistry and Molecular Biology, University of Southern California Norris Comprehensive Cancer Center, Keck School of Medicine of the University of Southern California, Los Angeles, CA 90033, USA
    Proc Natl Acad Sci U S A 99:3740-5. 2002
    ..This finding is compatible with the recent detection of 5-methylcytosine in Drosophila, and might suggest that S. cerevisiae has, or once had, CpG methylation...
  2. ncbi Distinct localization of histone H3 acetylation and H3-K4 methylation to the transcription start sites in the human genome
    Gangning Liang
    Department of Urology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, 1441 Eastlake Avenue, MS 8302L, Los Angeles, CA 90089 9181
    Proc Natl Acad Sci U S A 101:7357-62. 2004
    ..Common models depicting widespread histone acetylation and K4 methylation throughout the transcribed unit do not therefore apply to the majority of human genes...
  3. ncbi Origins of bidirectional promoters: computational analyses of intergenic distance in the human genome
    Daiya Takai
    Department of Biochemistry and Molecular Biology, USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, USA
    Mol Biol Evol 21:463-7. 2004
    ..This exclusion might be responsible for the existence of these divergent transcripts...
  4. ncbi Role of nucleosomal occupancy in the epigenetic silencing of the MLH1 CpG island
    Joy C Lin
    Department of Urology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089, USA
    Cancer Cell 12:432-44. 2007
    ..Activation of the promoter by demethylation with 5-aza-2'-deoxycytidine involves nucleosome eviction. Epigenetic silencing of tumor suppressor genes may involve heritable changes in nucleosome occupancy enabled by cytosine methylation...
  5. ncbi The CpG island searcher: a new WWW resource
    Daiya Takai
    Department of Biochemistry and Molecular Biology, USC Norris Comprehensive Cancer Center, Keck School of Medicine of the University of Southern California, Los Angeles, USA
    In Silico Biol 3:235-40. 2003
    ..The CpG Island Searcher is available on the World Wide Web at http://www.cpgislands.com or http://www.uscnorris.com/cpgislands/cpg.cgi...
  6. ncbi Establishment of conditional vectors for hairpin siRNA knockdowns
    Shiro Matsukura
    Department of Biochemistry and Molecular Biology, USC/Norris Comprehensive Cancer Center, Keck School of Medicine of the University of Southern California, 1441 Eastlake Avenue, Los Angeles, CA 90033, USA
    Nucleic Acids Res 31:e77. 2003
    ..Removal of the inducer, doxycycline, from treated cells led to re-expression of the targeted gene. Thus the method allows for a highly controlled approach to gene knockdown...
  7. ncbi Methylation-sensitive representational difference analysis and its application to cancer research
    Atsushi Kaneda
    Carcinogenesis Division, National Cancer Center Research Institute, Tokyo 104-0045, Japan
    Ann N Y Acad Sci 983:131-41. 2003
    ..MS-RDA is effective in identifying silenced genes in various cancers...
  8. ncbi Cryopreservation does not alter the allogenicity and development of vasculopathy in post-transplant rat aortas
    Aya Saito
    Department of Cardiothoracic Surgery, Graduate School of Medicine, The University of Tokyo, Japan
    Cryobiology 52:251-60. 2006
    ..However, the biological ramifications of cryopreservation are still unclear; therefore, using animal experiments we assessed how 'cryopreservation' influences graft allogenicity and cell viability...
  9. ncbi The induction of H3K9 methylation by PIWIL4 at the p16Ink4a locus
    Keiki Sugimoto
    Department of Respiratory Medicine, The University of Tokyo Hospital, Tokyo, Japan
    Biochem Biophys Res Commun 359:497-502. 2007
    ..The elevated level of histone methylation resulted in the downregulation of the p16(Ink4a) gene. These results suggest PIWIL4 plays important roles in the chromatin-modifying pathway in human somatic cells...