Research Topics
Genomes and GenesSpecies | Darren B TaichmanSummaryAffiliation: University of Pennsylvania Country: USA Publications
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Detail Information
Publications
Notch1 and Jagged1 expression by the developing pulmonary vasculatureDarren B Taichman
Pulmonary, Allergy and Critical Care Division, University of Pennsylvania Medical Center, Children s Hospital of Philadelphia and The University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
Dev Dyn 225:166-75. 2002..These temporal and spatial patterns in Notch1/Jagged1 gene and protein expression suggest multiple potential paths of cell-cell signaling during lung development and vascular morphogenesis...
A unique pattern of Tie1 expression in the developing murine lungDarren B Taichman
Pulmonary, Allergy and Critical Care Division, University of Pennsylvania, Philadelphia, USA
Exp Lung Res 29:113-22. 2003..This unique pattern of Tie1 gene expression in the embryonic and mature lung supports a distinct role for Tie1 in the development and function of the pulmonary vasculature...
Characterization of Notch receptor expression in the developing mammalian heart and liverKathleen M Loomes
Division of Gastroenterology, Department of Pediatrics, Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
Am J Med Genet 112:181-9. 2002..JAG1 is also expressed in cells adjacent to those expressing Notch2, suggesting a possible ligand receptor relationship. The Notch receptors have distinct roles in cell fate determination in different organ systems...
Misclassification of pulmonary hypertension due to reliance on pulmonary capillary wedge pressure rather than left ventricular end-diastolic pressureScott D Halpern
Division of Pulmonary, Allergy and Critical CareMedicine, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
Chest 136:37-43. 2009..We sought to determine the calibration, discrimination, and diagnostic accuracy of PCWP, using simultaneously measured left ventricular end-diastolic pressure (LVEDP) as the "gold standard."..
Cognitive, mood and quality of life impairments in a select population of ARDS survivorsMark E Mikkelsen
Division of Pulmonary and Critical Care Medicine, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
Respirology 14:76-82. 2009..This study investigated associations between cognitive impairment, mood disorders and quality of life in a select group of ARDS survivors...
Epidemiology of pulmonary arterial hypertensionDarren B Taichman
University of Pennsylvania School of Medicine, Penn Presbyterian Medical Center, 51 North 39th Street, 441 PHI Building, Philadelphia, PA 19104, USA
Clin Chest Med 28:1-22, vii. 2007..The risk factors for the development of pulmonary arterial hypertension, prognostic markers, and the effects of current therapies on survival are discussed...
Formation and validation of a telephone battery to assess cognitive function in acute respiratory distress syndrome survivorsJason D Christie
Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
J Crit Care 21:125-32. 2006..Describe initial development and validation of a test battery composed of established instruments designed to detect, via telephone interview, cognitive abnormalities in survivors of acute respiratory distress syndrome...
Health-related quality of life in patients with pulmonary arterial hypertensionDarren B Taichman
Pulmonary, Allergy and Critical Care Division, University of Pennsylvania School of Medicine, University of Pennsylvania Medical Center Presbyterian, Philadelphia, PA 19104, USA
Respir Res 6:92. 2005..However, comparatively little is known about health-related quality of life and its determinants in patients with pulmonary arterial hypertension...
Validation of a brief telephone battery for neurocognitive assessment of patients with pulmonary arterial hypertensionDarren B Taichman
Pulmonary, Allergy and Critical Care Division, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
Respir Res 6:39. 2005..We undertook this study to validate telephone administration of the tests...
Wide variation in clinicians' assessment of New York Heart Association/World Health Organization functional class in patients with pulmonary arterial hypertensionDarren B Taichman
Pulmonary, Allergy and Critical Care Division, University of Pennsylvania, Philadelphia, PA 19104, USA
Mayo Clin Proc 84:586-92. 2009....
Evaluation of disease-specific health-related quality of life in patients with pulmonary arterial hypertensionMichael Zlupko
Pulmonary, Allergy and Critical Care Division, Department of Medicine, University of Pennsylvania School of Medicine, Penn Presbyterian Medical Center, Suite 120, 51 North 39th Street, Philadelphia, PA 19104, USA
Respir Med 102:1431-8. 2008..The Minnesota Living with Heart Failure questionnaire was recently adapted and validated for HRQOL measurement in PAH. We applied this pulmonary hypertension-specific version (MLHF-PH) to a larger population of PAH patients...
Hemodynamics and survival in patients with pulmonary arterial hypertension related to systemic sclerosisSteven M Kawut
Pulmonary, Allergy, and Critical Care, University of Pennsylvania School of Medicine, Philadelphia, USA
Chest 123:344-50. 2003..The goal of this study was to determine whether the survival of patients with pulmonary hypertension related to systemic sclerosis (SScPH) was different from that of patients with other forms of pulmonary arterial hypertension...
Health-related quality of life and patient-reported outcomes in pulmonary arterial hypertensionHubert Chen
Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of California San Francisco, 350 Parnassus Avenue, Suite 609, San Francisco, CA 94143, USA
Proc Am Thorac Soc 5:623-30. 2008..As the use of PROs continues to increase, additional work will be needed to begin standardizing the reporting and interpretation of such outcomes in future clinical trials...
Hemodynamics and survival of patients with portopulmonary hypertensionSteven M Kawut
Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
Liver Transpl 11:1107-11. 2005..Future studies of the specific mechanisms of and therapy for pulmonary arterial hypertension should focus on the distinctions between the different forms of this disease...
Clinical risk factors for portopulmonary hypertensionSteven M Kawut
Division of Pulmonary, Allergy, and Critical Care Medicine, Columbia University College of Physicians and Surgeons, 622 West 168th Street, PH 8E, Room 101, New York, NY 10032, USA
Hepatology 48:196-203. 2008..Hormonal and immunologic factors may therefore be integral to the development of portopulmonary hypertension...
Therapy for pulmonary arterial hypertension: the more, the merrier?Darren B Taichman
Ann Intern Med 149:583-5. 2008
