CAROLE A SZTALRYD

Summary

Affiliation: University of Maryland
Country: USA

Publications

  1. pmc Perilipin A is essential for the translocation of hormone-sensitive lipase during lipolytic activation
    Carole Sztalryd
    Laboratory of Cellular and Developmental Biology, National Institute of Diabetes, Digestive, and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892 2715, USA
    J Cell Biol 161:1093-103. 2003
  2. ncbi request reprint Post-translational regulation of adipose differentiation-related protein by the ubiquitin/proteasome pathway
    Guoheng Xu
    Department of Physiology and Pathophysiology, Health Science Center of Peking University and Key Laboratory of Molecular Cardiovascular Sciences, Ministry of Education, Beijing 100083, China
    J Biol Chem 280:42841-7. 2005
  3. ncbi request reprint Perilipins: lipid droplet coat proteins adapted for tissue-specific energy storage and utilization, and lipid cytoprotection
    Carole Sztalryd
    The Geriatric Research, Education and Clinical Center, Baltimore Veterans Affairs Health Care Center, Baltimore, MD 21201, USA Division of Endocrinology, Department of Medicine, School of Medicine, University of Maryland, Baltimore, MD 21201, USA Electronic address
    Biochimie 96:96-101. 2014
  4. ncbi request reprint Functional compensation for adipose differentiation-related protein (ADFP) by Tip47 in an ADFP null embryonic cell line
    Carole Sztalryd
    Geriatric Research, Education and Clinical Center, Baltimore Veterans Affairs Health Care Center, Department of Medicine, School of Medicine, University of Maryland, Baltimore, Maryland 21201, USA
    J Biol Chem 281:34341-8. 2006
  5. pmc Consequences of lipid droplet coat protein downregulation in liver cells: abnormal lipid droplet metabolism and induction of insulin resistance
    Ming Bell
    Geriatric Research, Education and Clinical Center, Baltimore Veterans Affairs Health Care Center, Division of Gerontology, Department of Medicine, School of Medicine, University of Maryland, Baltimore, Maryland, USA
    Diabetes 57:2037-45. 2008
  6. pmc Activation of hormone-sensitive lipase requires two steps, protein phosphorylation and binding to the PAT-1 domain of lipid droplet coat proteins
    Hong Wang
    Geriatric Research, Education, and Clinical Center, Baltimore Veterans Affairs Health Care Center, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    J Biol Chem 284:32116-25. 2009
  7. ncbi request reprint Mutational analysis of the hormone-sensitive lipase translocation reaction in adipocytes
    Chun li Su
    Laboratory of Cellular and Developmental Biology, NIDDK, National Institutes of Health, Bethesda, Maryland 20892 8028, USA
    J Biol Chem 278:43615-9. 2003
  8. ncbi request reprint The central role of perilipin a in lipid metabolism and adipocyte lipolysis
    John T Tansey
    Chemistry Department, Otterbein College, Westerville, OH 43081, USA
    IUBMB Life 56:379-85. 2004
  9. ncbi request reprint Degradation of perilipin is mediated through ubiquitination-proteasome pathway
    Guoheng Xu
    Department of Physiology and Pathophysiology, Peking University Health Science Center, Beijing 100083, China
    Biochim Biophys Acta 1761:83-90. 2006

Research Grants

  1. Role of PAT proteins in ectopic fat deposition
    Carole Sztalryd; Fiscal Year: 2009
  2. Role of PAT proteins in ectopic fat deposition
    CAROLE A SZTALRYD; Fiscal Year: 2010
  3. Role of PAT proteins in ectopic fat deposition
    CAROLE A SZTALRYD; Fiscal Year: 2010
  4. Role of PAT proteins in ectopic fat deposition
    Carole Sztalryd; Fiscal Year: 2009
  5. Role of PAT proteins in ectopic fat deposition
    Carole Sztalryd; Fiscal Year: 2009

Collaborators

Detail Information

Publications9

  1. pmc Perilipin A is essential for the translocation of hormone-sensitive lipase during lipolytic activation
    Carole Sztalryd
    Laboratory of Cellular and Developmental Biology, National Institute of Diabetes, Digestive, and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892 2715, USA
    J Cell Biol 161:1093-103. 2003
    ....
  2. ncbi request reprint Post-translational regulation of adipose differentiation-related protein by the ubiquitin/proteasome pathway
    Guoheng Xu
    Department of Physiology and Pathophysiology, Health Science Center of Peking University and Key Laboratory of Molecular Cardiovascular Sciences, Ministry of Education, Beijing 100083, China
    J Biol Chem 280:42841-7. 2005
    ....
  3. ncbi request reprint Perilipins: lipid droplet coat proteins adapted for tissue-specific energy storage and utilization, and lipid cytoprotection
    Carole Sztalryd
    The Geriatric Research, Education and Clinical Center, Baltimore Veterans Affairs Health Care Center, Baltimore, MD 21201, USA Division of Endocrinology, Department of Medicine, School of Medicine, University of Maryland, Baltimore, MD 21201, USA Electronic address
    Biochimie 96:96-101. 2014
    ..Here, we review the current knowledge of the multiple perilipin proteins in regulating tissue-specific lipid droplets and associations with tissue and systemic energetics. ..
  4. ncbi request reprint Functional compensation for adipose differentiation-related protein (ADFP) by Tip47 in an ADFP null embryonic cell line
    Carole Sztalryd
    Geriatric Research, Education and Clinical Center, Baltimore Veterans Affairs Health Care Center, Department of Medicine, School of Medicine, University of Maryland, Baltimore, Maryland 21201, USA
    J Biol Chem 281:34341-8. 2006
    ..Tip47 and ADFP in peripheral tissues may play a critical role in regulating the formation and turnover, and hence metabolic consequences, of ectopic fat...
  5. pmc Consequences of lipid droplet coat protein downregulation in liver cells: abnormal lipid droplet metabolism and induction of insulin resistance
    Ming Bell
    Geriatric Research, Education and Clinical Center, Baltimore Veterans Affairs Health Care Center, Division of Gerontology, Department of Medicine, School of Medicine, University of Maryland, Baltimore, Maryland, USA
    Diabetes 57:2037-45. 2008
    ..Our hypothesis is that PAT proteins modulate LD metabolism and therefore insulin resistance...
  6. pmc Activation of hormone-sensitive lipase requires two steps, protein phosphorylation and binding to the PAT-1 domain of lipid droplet coat proteins
    Hong Wang
    Geriatric Research, Education, and Clinical Center, Baltimore Veterans Affairs Health Care Center, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    J Biol Chem 284:32116-25. 2009
    ....
  7. ncbi request reprint Mutational analysis of the hormone-sensitive lipase translocation reaction in adipocytes
    Chun li Su
    Laboratory of Cellular and Developmental Biology, NIDDK, National Institutes of Health, Bethesda, Maryland 20892 8028, USA
    J Biol Chem 278:43615-9. 2003
    ..Thus, HSL translocation requires the phosphorylation of both HSL and perilipin...
  8. ncbi request reprint The central role of perilipin a in lipid metabolism and adipocyte lipolysis
    John T Tansey
    Chemistry Department, Otterbein College, Westerville, OH 43081, USA
    IUBMB Life 56:379-85. 2004
    ..This review will focus on adipocyte lipolysis with emphasis on hormone signal transduction, lipolytic enzymes, the lipid storage droplet, and fatty acid release from the adipocyte...
  9. ncbi request reprint Degradation of perilipin is mediated through ubiquitination-proteasome pathway
    Guoheng Xu
    Department of Physiology and Pathophysiology, Peking University Health Science Center, Beijing 100083, China
    Biochim Biophys Acta 1761:83-90. 2006
    ..We conclude that the degradation of perilipin is mediated through an ubiquitination-proteasome pathway, which suggests another mode for the post-translational regulation of perilipin...

Research Grants6

  1. Role of PAT proteins in ectopic fat deposition
    Carole Sztalryd; Fiscal Year: 2009
    ..These proposed studies will test this hypothesis, and if correct provide an approach for prevention of disease or therapeutic intervention. ..
  2. Role of PAT proteins in ectopic fat deposition
    CAROLE A SZTALRYD; Fiscal Year: 2010
    ..These proposed studies will test this hypothesis, and if correct provide an approach for prevention of disease or therapeutic intervention. ..
  3. Role of PAT proteins in ectopic fat deposition
    CAROLE A SZTALRYD; Fiscal Year: 2010
    ..These proposed studies will test this hypothesis, and if correct provide an approach for prevention of disease or therapeutic intervention. ..
  4. Role of PAT proteins in ectopic fat deposition
    Carole Sztalryd; Fiscal Year: 2009
    ..These proposed studies will test this hypothesis, and if correct provide an approach for prevention of disease or therapeutic intervention. ..
  5. Role of PAT proteins in ectopic fat deposition
    Carole Sztalryd; Fiscal Year: 2009
    ..These proposed studies will test this hypothesis, and if correct provide an approach for prevention of disease or therapeutic intervention. ..