- Genome-wide scan for copy number variation association with age at onset of Alzheimer's diseaseKinga Szigeti
Department of Neurology, University at Buffalo SUNY, Buffalo, NY 14203, USA
J Alzheimers Dis 33:517-23. 2013..The CR1 events are consistent with previous reports. Larger scale studies with deeper genotyping specifically addressing CNV are needed to evaluate the significance of these findings...
- Should EOAD patients be included in clinical trials?Kinga Szigeti
Department of Neurology and Alzheimer s Disease and Memory Disorders Center, Baylor College of Medicine, 7200B Cambridge Street, Suite E5, 101, Houston, TX 77030, USA
Alzheimers Res Ther 3:4. 2011..Finally, we discuss the ethical dilemma of non-abandonment and justice as it pertains to exclusion of the early-onset AD patients from clinical trials...
- Olfactory copy number association with age at onset of Alzheimer diseaseC A Shaw
Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA
Neurology 76:1302-9. 2011..Alzheimer disease (AD) has high heritability for occurrence and age at onset (AAO). We performed a cases-only genome-wide CNV association study for age at onset of AD...
- Integrated copy number and gene expression analysis detects a CREB1 association with Alzheimer's diseaseY Li
Department of Neurology, Alzheimer s Disease and Memory Disorders Center, Baylor College of Medicine, Houston, TX, USA
Transl Psychiatry 2:e192. 2012..The association of the CNV to AD was confirmed by a case-control association study consisting of the Texas Alzheimer Research and Care Consortium and NIA-LOAD Family Study data sets...