Ben G Szaro

Summary

Affiliation: University at Albany
Country: USA

Publications

  1. doi request reprint Post-transcriptional control of neurofilaments: New roles in development, regeneration and neurodegenerative disease
    Ben G Szaro
    Department of Biological Sciences and the Neuroscience Research Center, University at Albany, SUNY, 1400 Washington Avenue, Albany, NY 12222, USA
    Trends Neurosci 33:27-37. 2010
  2. doi request reprint A crucial role for hnRNP K in axon development in Xenopus laevis
    Yuanyuan Liu
    The Department of Biological Sciences and the Center for Neuroscience Research, University at Albany, State University of New York, Albany, NY 12222, USA
    Development 135:3125-35. 2008
  3. doi request reprint Transcriptional and translational dynamics of light neurofilament subunit RNAs during Xenopus laevis optic nerve regeneration
    Lakshminarayanan Ananthakrishnan
    Department of Biological Sciences, University at Albany, State University of New York, Albany, NY 12222, USA
    Brain Res 1250:27-40. 2009
  4. doi request reprint c-Jun N-terminal kinase phosphorylation of heterogeneous nuclear ribonucleoprotein K regulates vertebrate axon outgrowth via a posttranscriptional mechanism
    Erica J Hutchins
    Department of Biological Sciences and the Center for Neuroscience Research, University at Albany, State University of New York, Albany, New York 12222
    J Neurosci 33:14666-80. 2013
  5. ncbi request reprint Neurofilament content is correlated with branch length in developing collateral branches of Xenopus spinal cord neurons
    Andrew Smith
    Department of Biological Sciences and the Neuroscience Research Center, University at Albany, State University of New York, 1400 Washington Avenue, Albany, NY 12222, USA
    Neurosci Lett 403:283-7. 2006
  6. doi request reprint Metamorphosis and the regenerative capacity of spinal cord axons in Xenopus laevis
    Kurt M Gibbs
    Department of Biological Sciences, University at Albany, State University of New York, Albany, NY 12222, USA
    Eur J Neurosci 33:9-25. 2011
  7. doi request reprint Heterogeneous nuclear ribonucleoprotein K, an RNA-binding protein, is required for optic axon regeneration in Xenopus laevis
    Yuanyuan Liu
    Department of Biological Sciences and the Center for Neuroscience Research, University at Albany, State University of New York, Albany, NY 12222, USA
    J Neurosci 32:3563-74. 2012
  8. ncbi request reprint Post-transcriptional control of neurofilaments in development and disease
    Amar Thyagarajan
    Department of Biological Sciences and the Neuroscience Research Center, University at Albany, SUNY, 1400 Washington Avenue, Albany, NY 12222, USA
    Exp Cell Res 313:2088-97. 2007
  9. doi request reprint hnRNP K post-transcriptionally co-regulates multiple cytoskeletal genes needed for axonogenesis
    Yuanyuan Liu
    Department of Biological Sciences and the Center for Neuroscience Research, University at Albany, State University of New York, Albany, NY 12222, USA
    Development 138:3079-90. 2011
  10. ncbi request reprint Dynamic endogenous association of neurofilament mRNAs with K-homology domain ribonucleoproteins in developing cerebral cortex
    Amar Thyagarajan
    Department of Biological Sciences and the Center for Neuroscience Research, University at Albany, State University of New York, Albany, New York 12222, USA
    Brain Res 1189:33-42. 2008

Collaborators

  • Michael J Strong
  • Sridar V Chittur
  • Yuanyuan Liu
  • Amar Thyagarajan
  • Christine Gervasi
  • Kurt M Gibbs
  • Erica J Hutchins
  • Lakshminarayanan Ananthakrishnan
  • Andrew Smith
  • Hurong Yu
  • Sarah K Deaton

Detail Information

Publications14

  1. doi request reprint Post-transcriptional control of neurofilaments: New roles in development, regeneration and neurodegenerative disease
    Ben G Szaro
    Department of Biological Sciences and the Neuroscience Research Center, University at Albany, SUNY, 1400 Washington Avenue, Albany, NY 12222, USA
    Trends Neurosci 33:27-37. 2010
    ..Such studies herald a novel approach to understanding how neurons coordinate the expressions of functionally related proteins and provide new insights into how the dysregulation of this control can lead to disease...
  2. doi request reprint A crucial role for hnRNP K in axon development in Xenopus laevis
    Yuanyuan Liu
    The Department of Biological Sciences and the Center for Neuroscience Research, University at Albany, State University of New York, Albany, NY 12222, USA
    Development 135:3125-35. 2008
    ..Our study supports the idea that translation of at least a subset of RNAs involved in axon development is controlled by post-transcriptional regulatory modules that have hnRNP K as an essential element...
  3. doi request reprint Transcriptional and translational dynamics of light neurofilament subunit RNAs during Xenopus laevis optic nerve regeneration
    Lakshminarayanan Ananthakrishnan
    Department of Biological Sciences, University at Albany, State University of New York, Albany, NY 12222, USA
    Brain Res 1250:27-40. 2009
    ..These increases are subsequently modulated post-transcriptionally to accommodate shifting demands at each phase of regeneration for NF heteropolymers of differing composition in regrowing axons...
  4. doi request reprint c-Jun N-terminal kinase phosphorylation of heterogeneous nuclear ribonucleoprotein K regulates vertebrate axon outgrowth via a posttranscriptional mechanism
    Erica J Hutchins
    Department of Biological Sciences and the Center for Neuroscience Research, University at Albany, State University of New York, Albany, New York 12222
    J Neurosci 33:14666-80. 2013
    ..Thus, in addition to its known roles in transcription and cytoskeletal organization, JNK acts posttranscriptionally through hnRNP K to regulate translation of proteins crucial for axonogenesis. ..
  5. ncbi request reprint Neurofilament content is correlated with branch length in developing collateral branches of Xenopus spinal cord neurons
    Andrew Smith
    Department of Biological Sciences and the Neuroscience Research Center, University at Albany, State University of New York, 1400 Washington Avenue, Albany, NY 12222, USA
    Neurosci Lett 403:283-7. 2006
    ..These lengths correspond remarkably well with lengths associated with branch stabilization. Given that NFs are the most stable of the cytoskeletal polymers, we speculate that they may contribute to this stabilization...
  6. doi request reprint Metamorphosis and the regenerative capacity of spinal cord axons in Xenopus laevis
    Kurt M Gibbs
    Department of Biological Sciences, University at Albany, State University of New York, Albany, NY 12222, USA
    Eur J Neurosci 33:9-25. 2011
    ....
  7. doi request reprint Heterogeneous nuclear ribonucleoprotein K, an RNA-binding protein, is required for optic axon regeneration in Xenopus laevis
    Yuanyuan Liu
    Department of Biological Sciences and the Center for Neuroscience Research, University at Albany, State University of New York, Albany, NY 12222, USA
    J Neurosci 32:3563-74. 2012
    ..Our study therefore provides evidence of a novel post-transcriptional regulatory pathway orchestrated by hnRNP K that is essential for successful CNS axon regeneration...
  8. ncbi request reprint Post-transcriptional control of neurofilaments in development and disease
    Amar Thyagarajan
    Department of Biological Sciences and the Neuroscience Research Center, University at Albany, SUNY, 1400 Washington Avenue, Albany, NY 12222, USA
    Exp Cell Res 313:2088-97. 2007
    ....
  9. doi request reprint hnRNP K post-transcriptionally co-regulates multiple cytoskeletal genes needed for axonogenesis
    Yuanyuan Liu
    Department of Biological Sciences and the Center for Neuroscience Research, University at Albany, State University of New York, Albany, NY 12222, USA
    Development 138:3079-90. 2011
    ..These experiments provide evidence that hnRNP K is the nexus of a novel post-transcriptional regulatory module controlling the synthesis of proteins that integrate all three cytoskeletal polymers to form the axon...
  10. ncbi request reprint Dynamic endogenous association of neurofilament mRNAs with K-homology domain ribonucleoproteins in developing cerebral cortex
    Amar Thyagarajan
    Department of Biological Sciences and the Center for Neuroscience Research, University at Albany, State University of New York, Albany, New York 12222, USA
    Brain Res 1189:33-42. 2008
    ..This study is consistent with a model whereby these RNPs and NF mRNAs are components of a dynamic post-transcriptional regulatory module that influences the cytoskeletal compositions of neurons...
  11. ncbi request reprint Performing functional studies of Xenopus laevis intermediate filament proteins through injection of macromolecules into early embryos
    Christine Gervasi
    Department of Biological Sciences and the Center for Neuroscience Research, University at Albany, State University of New York, Albany, New York 12222, USA
    Methods Cell Biol 78:673-701. 2004
  12. ncbi request reprint Phylogenetically conserved binding of specific K homology domain proteins to the 3'-untranslated region of the vertebrate middle neurofilament mRNA
    Amar Thyagarajan
    Department of Biological Sciences and the Center for Neuroscience Research, University at Albany, State University of New York, Albany, New York 12222, USA
    J Biol Chem 279:49680-8. 2004
    ..Since hnRNP E is known to stabilize mRNAs, these results raise the hypothesis that these proteins may contribute to the increases in cytoplasmic levels of NF-M mRNA that accompany axonal maturation...
  13. ncbi request reprint Regeneration of descending projections in Xenopus laevis tadpole spinal cord demonstrated by retrograde double labeling
    Kurt M Gibbs
    Department of Biological Sciences, University at Albany, State University of New York, 1400 Washington Avenue, Albany, NY 12222, USA
    Brain Res 1088:68-72. 2006
    ....
  14. ncbi request reprint Increased expression of multiple neurofilament mRNAs during regeneration of vertebrate central nervous system axons
    Christine Gervasi
    Department of Biological Sciences, State University of New York University at Albany, Albany, New York 12222, USA
    J Comp Neurol 461:262-75. 2003
    ..These results are consistent with the hypothesis that successful axon regeneration involves changes in nIF subunit composition conducive to growth and argue that a successful injury response differs between CNS and PNS...