Research Topics
Species | J P SzaflarskiSummaryAffiliation: University of Cincinnati Country: USA Publications
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Publications
A 10-year longitudinal fMRI study of narrative comprehension in children and adolescentsJerzy P Szaflarski
Department of Neurology, University of Cincinnati Academic Health Center, Cincinnati, OH, USA Pediatric Neuroimaging Research Consortium, Cincinnati Children s Hospital Medical Center, Cincinnati, OH, USA Electronic address
Neuroimage 63:1188-95. 2012....- Topiramate and its effect on fMRI of language in patients with right or left temporal lobe epilepsyJerzy P Szaflarski
Department of Neurology, University of Cincinnati Academic Health Center, Cincinnati, OH 45267 0525, USA
Epilepsy Behav 24:74-80. 2012..These findings may, in part, explain the negative effects of TPM on cognition and language performance and support the notion that TPM may affect the results of language fMRI lateralization/localization... - Left-handedness and language lateralization in childrenJerzy P Szaflarski
Department of Neurology, University of Cincinnati Academic Health Center, Cincinnati, OH, USA
Brain Res 1433:85-97. 2012..e., independent of handedness) indicating the presence of similar mechanisms for language lateralization in left- and right-handed children... 
The use of standardized patients for mock oral board exams in neurology: a pilot studyBrett Kissela
Department of Neurology, University of Cincinnati, Cincinnati, OH 45267 0525, USA
BMC Med Educ 6:22. 2006..We sought to create a standardized patient mock oral board exam that would allow comparison of residents' clinical performance...- Seizure control in patients with idiopathic generalized epilepsies: EEG determinants of medication responseJerzy P Szaflarski
Department of Neurology, University of Cincinnati, Cincinnati, OH 45267 0525, USA
Epilepsy Behav 17:525-30. 2010..These findings suggest that patients with IGEs with poor seizure control may have atypical IGEs with possibly focal, for example, frontal, rather than thalamic onset... 
Incidence of seizures in the acute phase of stroke: a population-based studyJerzy P Szaflarski
Department of Neurology and the Neuroscience Institute, University of Cincinnati Academic Health Center, Cincinnati, Ohio 45267 0525, USA
Epilepsia 49:974-81. 2008..We aimed to establish the incidence of acute poststroke seizures in a biracial cohort and to determine whether acute seizure occurrence differs by race/ethnicity, stroke subtype, and/or stroke localization...- Prospective, randomized, single-blinded comparative trial of intravenous levetiracetam versus phenytoin for seizure prophylaxisJerzy P Szaflarski
Department of Neurology, University of Cincinnati Academic Health Center, 260 Stetson Street, Rm 2350, Cincinnati, OH 45267 0525, USA
Neurocrit Care 12:165-72. 2010..Anti-epileptic drugs are commonly used for seizure prophylaxis after neurological injury. We performed a study comparing intravenous (IV) levetiracetam (LEV) to IV phenytoin (PHT) for seizure prophylaxis after neurological injury... 
Four-year incidence of psychogenic nonepileptic seizures in adults in hamilton county, OHJ P Szaflarski
Department of Neurology, University of Cincinnati Medical Center, OH 45267 0505, USA
Neurology 55:1561-3. 2000..The mean incidence of psychogenic nonepileptic seizures was 3.03/100,000, with the highest incidence in 1998 (4.6/100,000). Most patients with the diagnosis of psychogenic nonepileptic seizures were aged 25 to 45 years (4.38/100,000)...- Seizure control in patients with epilepsy: the physician vs. medication factorsJerzy P Szaflarski
Department of Neurology and the Cincinnati Epilepsy Center, University of Cincinnati Academic Health Center, Cincinnati, OH, USA
BMC Health Serv Res 8:264. 2008..This study compares the relative effects of provider type (epileptologist vs. other neurologist) and pharmacologic treatment (newer vs. older antiepileptic drugs) on seizure control in patients with epilepsy... - Levetiracetam use in critically ill patientsJerzy P Szaflarski
Department of Neurology, University of Cincinnati Medical Center, MSB Rm 4506, ML 0525, 231 Albert B Sabin Way, Cincinnati, OH 45267 0525, USA
Neurocrit Care 7:140-7. 2007..Levetiracetam (LEV) is used in the setting of acute brain injury for seizure treatment or prophylaxis but its safety and efficacy in this setting is unknown... - Comprehensive presurgical functional MRI language evaluation in adult patients with epilepsyJerzy P Szaflarski
Department of Neurology, University of Cincinnati Academic Health Center, Cincinnati, OH 45267 0525, USA
Epilepsy Behav 12:74-83. 2008.... - Constraint-induced aphasia therapy stimulates language recovery in patients with chronic aphasia after ischemic strokeJerzy P Szaflarski
Department of Neurology, University of Cincinnati Academic Health Center, Cincinnati, OH, U S A and The Neuroscience Institute, Cincinnati, OH 45267 0525, USA
Med Sci Monit 14:CR243-250. 2008..The goals of this pilot study were to implement the original German CIAT protocol, refine the treatment program, and confirm its efficacy in patients with chronic aphasia... - fMRI study of language lateralization in children and adultsJerzy P Szaflarski
Department of Neurology, University of Cincinnati Medical Center, Cincinnati, Ohio 45267 0525, USA
Hum Brain Mapp 27:202-12. 2006..Our findings indicate that language lateralization to the dominant hemisphere increases between the ages 5 and 20 years, plateaus between 20 and 25 years, and slowly decreases between 25 and 70 years... - Seizure disorders, depression, and health-related quality of lifeJerzy P Szaflarski
Department of Neurology and Cincinnati Epilepsy Center, University of Cincinnati Medical Center, Cincinnati, OH 45267 0525, USA
Epilepsy Behav 5:50-7. 2004..We conclude that evaluating and treating mood states is as important as treating PNES itself when caring for patients with PNES, and it might be the first step toward improving their QOL... - Quality of life in psychogenic nonepileptic seizuresJerzy P Szaflarski
Department of Neurology and Institute for Health Policy and Health Services Research, University of Cincinnati, Cincinnati, Ohio, U S A
Epilepsia 44:236-42. 2003..The relation between these factors and PNESs is not well established. In this study, we compared HRQOL in patients with PNESs with that of patients with ESs... - Excitatory repetitive transcranial magnetic stimulation induces improvements in chronic post-stroke aphasiaJerzy P Szaflarski
Department of Neurology, University of Cincinnati Academic Health Center, Cincinnati, OH 45267 0525, USA
Med Sci Monit 17:CR132-9. 2011.... - Poststroke aphasia recovery assessed with functional magnetic resonance imaging and a picture identification taskJerzy P Szaflarski
Department of Neurology, University of Cincinnati Academic Health Center, Cincinnati, Ohio 45267 0525, USA
J Stroke Cerebrovasc Dis 20:336-45. 2011..This study documents the utility of the picture-identification task for poststroke language recovery evaluation. Our data suggest that adult stroke patients use functional peristroke areas to perform language functions... - Effects of zonisamide on the electroencephalogram of a patient with juvenile myoclonic epilepsyJerzy P Szaflarski
Department of Neurology, University of Cincinnati Medical Center, Cincinnati, OH 45267 0525, USA
Epilepsy Behav 5:1024-6. 2004..This case report suggests that zonisamide may be effective in the treatment of medication-resistant idiopathic generalized epilepsy and that it may lead to a significant improvement of the EEG... - Language lateralization in left-handed and ambidextrous people: fMRI dataJ P Szaflarski
Department of Neurology, University of Cincinnati Medical Center, Cincinnati, OH 45267, USA
Neurology 59:238-44. 2002..The authors examined language distribution in these subjects and evaluated the relationships between personal handedness, family history of sinistrality, and a language laterality index (LI) measured with fMRI... - Cortical and subcortical contributions to absence seizure onset examined with EEG/fMRIJerzy P Szaflarski
Department of Neurology, University of Cincinnati Medical Center, Cincinnati, OH 45267 0525, USA
Epilepsy Behav 18:404-13. 2010.... - Application of signal detection theory to verbal memory testing to distinguish patients with psychogenic nonepileptic seizures from patients with epileptic seizuresKelly A McNally
Department of Psychology, University of Cincinnati, Cincinnati, OH 45221 0376, USA
Epilepsy Behav 14:597-603. 2009.... - Compensatory brain activation for recognition memory in patients with medication-resistant epilepsyJames C Eliassen
Center for Imaging Research, Cincinnati Epilepsy Center, University of Cincinnati Academic Health Center, Cincinnati, OH 45267 0525, USA
Epilepsy Behav 13:463-9. 2008.... - Accuracy of self-reported neuropsychological functioning in individuals with epileptic or psychogenic nonepileptic seizuresJamison D Fargo
Department of Psychology, University of Cincinnati, Cincinnati, OH, USA
Epilepsy Behav 5:143-50. 2004..Given the inaccuracies that exist in patient self-report, results highlight the importance of a comprehensive neuropsychological assessment when evaluating the neurocognitive status of individuals with seizures... - Optimism, pessimism, and neuropsychological performance across semiology-based subtypes of psychogenic nonepileptic seizuresNathan M Griffith
Department of Psychology, University of Cincinnati, Cincinnati, OH 45221, USA
Epilepsy Behav 13:478-84. 2008..Overall, the results of the present study suggest that classification into semiology-based subtypes and study of normal personality traits among patients with PNES may have clinical significance... - Functional magnetic resonance imaging reveals atypical language organization in children following perinatal left middle cerebral artery strokeL M Jacola
Division of Neurology, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229 3039, USA
Neuropediatrics 37:46-52. 2006..Stroke subjects instead showed bilateral or right lateralization (verb generation) and bilateral activation (R > L) (story listening). Language is distributed atypically in children with perinatal left hemisphere stroke... - Psychopathology and quality of life: psychogenic non-epileptic seizures versus epilepsyJerzy P Szaflarski
Department of Neurology, University of Cincinnati Medical Center, Cincinnati, OH, USA
Med Sci Monit 9:CR113-8. 2003..Future studies should examine causal linkages between psychopathology and PNES and other explanations in seizure-related QOL... - Age accounts for racial differences in ischemic stroke volume in a population-based studyTarek Zakaria
Department of Neurology, University of Cincinnati, Cincinnati, Ohio 45267 0525, USA
Cerebrovasc Dis 26:376-80. 2008..5 cm. However, it is not known if stroke volume was similar between black and white patients within the same study population... - Quality of life in medication-resistant epilepsy: the effects of patient's age, age at seizure onset, and disease durationMagdalena Szaflarski
Institute for the Study of Health, University of Cincinnati, Cincinnati, OH, USA
Epilepsy Behav 8:547-51. 2006..Interventions to improve HRQOL in patients with medication-resistant epilepsy should, therefore, focus on treating mood disturbances and minimizing medication side effects... - Cortical reorganization of language functioning following perinatal left MCA strokeJan Mendelt Tillema
Division of Neurology, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229 3039, USA
Brain Lang 105:99-111. 2008..Functional MRI was used to determine differences in patterns of cortical activation between children who suffered perinatal left middle cerebral artery (MCA) stroke and healthy children performing a silent verb generation task... - The effects of duration of intractable epilepsy on memory functionGlenn P Kent
Department of Psychology, University of Cincinnati, Cincinnati, OH, USA
Epilepsy Behav 9:469-77. 2006..These results have implications for the strategy of treatment and counseling of patients with intractable temporal lobe epilepsy... - Cortical plasticity following motor skill learning during mental practice in strokeStephen J Page
Department of Physical Medicine and Rehabilitation, University of Cincinnati Academic Medical Center, Cincinnati, Ohio 45267 0394, USA
Neurorehabil Neural Repair 23:382-8. 2009..As a next step, this 10-subject case series examined the possibility that cortical plasticity is a mechanism underlying the treatment effect of MP when combined with RTP... - Reprint of "Cortical reorganization of language functioning following perinatal left MCA stroke" [Brain and Language 105 (2008) 99-111]Jan Mendelt Tillema
Division of Neurology, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229 3039, USA
Brain Lang 106:184-94. 2008..Functional MRI was used to determine differences in patterns of cortical activation between children who suffered perinatal left middle cerebral artery (MCA) stroke and healthy children performing a silent verb generation task... - Moderating effect of optimism on emotional distress and seizure control in adults with temporal lobe epilepsyKiely M Donnelly
Department of Psychology, University of Cincinnati, One Edwards Center, Cincinnati, OH 45221, USA
Epilepsy Behav 18:374-80. 2010..An interaction between emotional distress and explanatory style was not observed. Thus, for individuals with higher levels of intelligence, depression may be an important pathway in linking emotional distress to poor seizure control... - Affected arm use and cortical change in stroke patients exhibiting minimal hand movementStephen J Page
University of Cincinnati, Cincinnati, OH, USA
Neurorehabil Neural Repair 24:195-203. 2010..In light of these challenges, the current study examined the efficacy of a repetitive task-specific training (RTP) regimen using an electrical stimulation neuroprosthesis in stroke patients exhibiting no affected wrist or hand movement... - The effect of seizures on working memory and executive functioning performanceLeah Chapman Black
Department of Psychology, University of Cincinnati, Cincinnati, OH 45221 0376, USA
Epilepsy Behav 17:412-9. 2010..These results have implications for early diagnosis and intervention in both groups... - The use of self-generation procedures facilitates verbal memory in individuals with seizure disordersBruce K Schefft
Department of Psychology, University of Cincinnati, Cincinnati, OH 45221 0376, USA
Epilepsy Behav 13:162-8. 2008..A memory encoding strategy that actively involves patient participation enhances memory performance... - Genetic and environmental risk factors for intracerebral hemorrhage: preliminary results of a population-based studyDaniel Woo
Department of Neurology, University of Cincinnati, Cincinnati, Ohio 45267 0525, USA
Stroke 33:1190-5. 2002..We report a preplanned, midpoint analysis of the first population-based, case-control study that examines both genetic and environmental risk factors of ICH... - Racial/ethnic disparities in the treatment of epilepsy: what do we know? What do we need to know?Magdalena Szaflarski
Institute for the Study of Health, University of Cincinnati, Cincinnati, OH, USA
Epilepsy Behav 9:243-64. 2006..We propose a framework to identify the array of disparities, points of intervention, and interventions... - Relationship between semiology of psychogenic nonepileptic seizures and Minnesota Multiphasic Personality Inventory profileNathan M Griffith
Department of Psychology, Cincinnati, OH, USA
Epilepsy Behav 11:105-11. 2007..Our study also may inform the methodology of future investigations of psychopathology among patients with PNES by providing support for content-based interpretation of the MMPI... - fMRI shows atypical language lateralization in pediatric epilepsy patientsWeihong Yuan
Cincinnati Children's Hospital Medical Center, Imaging Research Center, Cincinnati, Ohio 45229, USA
Epilepsia 47:593-600. 2006..234, p<0.05). CONCLUSIONS: This study shows that epilepsy during childhood is associated with neuroplasticity and reorganization of language function... - Measuring depressive symptoms among treatment-resistant seizure disorder patients: POMS Depression scale as an alternative to the BDI-IINathan M Griffith
Department of Psychology, University of Cincinnati, Cincinnati, OH, USA
Epilepsy Behav 7:266-72. 2005..These results suggest that the POMS-D may be effective in measuring reported depressive symptoms among seizure disorder patients... - Epidemiology of ischemic stroke in patients with diabetes: the greater Cincinnati/Northern Kentucky Stroke StudyBrett M Kissela
Department of Neurology, University of Cincinnati, 231 Albert Sabin Way, ML 0525, Cincinnati, OH 45267 0525, USA
Diabetes Care 28:355-9. 2005..Diabetes is a well known risk factor for stroke, but the impact of diabetes on stroke incidence rates is not known. This study uses a population-based study to describe the epidemiology of ischemic stroke in diabetic patients... - High-resolution functional MRI at 3T in healthy and epilepsy subjects: hippocampal activation with picture encoding taskJerzy P Szaflarski
Department of Neurology, University of Cincinnati Medical Center, Cincinnati, OH, USA
Epilepsy Behav 5:244-52. 2004..Furthermore, these results suggest that a larger study to test the utility of high-resolution fMRI in epilepsy presurgical evaluation is needed... - Medial temporal fMRI activation reflects memory lateralization and memory performance in patients with epilepsyJennifer Vannest
Division of Neurology, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229 3039, USA
Epilepsy Behav 12:410-8. 2008..Neither age of onset nor duration of epilepsy was significantly related to LI. These results indicate that focal epilepsy may influence the functional neuroanatomy of memory function... - Hypercholesterolemia, HMG-CoA reductase inhibitors, and risk of intracerebral hemorrhage: a case-control studyDaniel Woo
Department of Neurology and the Neuroscience Institute, University of Cincinnati, College of Medicine, 231 Bethesda Avenue ML 0525, Cincinnati, Ohio 45267 0525, USA
Stroke 35:1360-4. 2004..We tested the hypothesis that hypercholesterolemia or use of HMG-CoA reductase inhibitors (statin) agents, or both, are associated with ICH... - Clinical work intensity among physician specialties: how might we assess it? What do we find?Ronnie D Horner
Department of Public Health Sciences, University of Cincinnati, Cincinnati, OH 45219, USA
Med Care 49:108-13. 2011..The utility of available instruments for clinical work intensity assessment is unknown... - Temporal and subjective work demands in office-based patient care: an exploration of the dimensions of physician work intensityC Jeff Jacobson
Department of Anthropology, University of Cincinnati, Cincinnati, OH, USA
Med Care 49:52-8. 2011..Existing, brief work intensity measures have been used in physician studies, but their validity in clinical settings has not been established... - Valproic acid blood genomic expression patterns in children with epilepsy - a pilot studyY Tang
Department of Neurology, University of Cincinnati, Cincinnati, OH, USA
Acta Neurol Scand 109:159-68. 2004..These expression patterns provide new insight into previously undetected mechanisms of VPA anticonvulsant activity... - A group independent component analysis of covert verb generation in children: a functional magnetic resonance imaging studyPrasanna Karunanayaka
Imaging Research Center, Children s Hospital Research Foundation, Children s Hospital Medical Center, and Department of Neurology and Center for Imaging Research, University of Cincinnati, Cincinnati, OH 45229, USA
Neuroimage 51:472-87. 2010..In this context, group ICA of fMRI data from our large sample of children aged 5-18 years provides strong evidence in support of the regionally weighted model for cognitive neurodevelopment of language networks... - Cortical reorganization following modified constraint-induced movement therapy: a study of 4 patients with chronic strokeJerzy P Szaflarski
Department of Neurology, University of Cincinnati Medical Center, OH 45267, USA
Arch Phys Med Rehabil 87:1052-8. 2006..Because mCIMT is more easily administered than longer duration protocols, mCIMT may be a more practicable way of studying plasticity... - Seizures are common in the acute setting of childhood stroke: a population-based studyMadeline A Chadehumbe
Division of Child Neurology, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio, USA
J Child Neurol 24:9-12. 2009..As compared with adults, seizures within the acute setting of childhood stroke are common with an occurrence rate in our population of 58%... - Reliability of fMRI for studies of language in post-stroke aphasia subjectsKenneth P Eaton
Imaging Research Center, Cincinnati Children s Hospital Research Foundation, Cincinnati, Ohio, USA
Neuroimage 41:311-22. 2008..These quantitative measures of inter-scan variability support the proposed use of these fMRI paradigms for longitudinal mapping of neural reorganization of language processing following left hemispheric insult... - Language networks in children: evidence from functional MRI studiesJennifer Vannest
Pediatric Neuroimaging Research Consortium, Cincinnati Children s Hospital Research Foundation and Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229 5033, USA
AJR Am J Roentgenol 192:1190-6. 2009..Multiple fMRI tasks for pediatric patients characterize functional brain reorganization that may accompany language deficits... - Brain-mapping techniques for evaluating poststroke recovery and rehabilitation: a reviewJames C Eliassen
Center for Imaging Research, University of Cincinnati Academic Health Center, Cincinnati, Ohio, USA
Top Stroke Rehabil 15:427-50. 2008..The authors also provide suggestions on using these techniques in tandem to more thoroughly address the outstanding questions in the field... - Chronic isolated hemifacial spasm as a manifestation of epilepsia partialis continuaAlberto J Espay
Department of Neurology and the Neuroscience Institute, University of Cincinnati Academic Health Center, Cincinnati, OH 45267 0525, USA
Epilepsy Behav 12:332-6. 2008.... - Age-related connectivity changes in fMRI data from children listening to storiesPrasanna R Karunanayaka
Imaging Research Center, Children s Hospital Medical Center, 3333 Burnet Ave ML 5031, Cincinnati, OH 45229, USA
Neuroimage 34:349-60. 2007..The classical Wernicke-Geschwind (WG) model for speech processing is expanded to a two-route model involving a direct route between Broca's and Wernicke's area and an indirect route involving the parietal lobe... - Simultaneous EEG/functional magnetic resonance imaging at 4 Tesla: correlates of brain activity to spontaneous alpha rhythm during relaxationMark W DiFrancesco
Division of Pediatric Radiology, Cincinnati Children s Hospital Medical Center, Pediatric Neuroimaging Research Consortium, Cincinnati, Ohio, USA
J Clin Neurophysiol 25:255-64. 2008.... - A longitudinal functional magnetic resonance imaging study of language development in children 5 to 11 years oldJerzy P Szaflarski
Department of Neurology, University of Cincinnati Medical Center, OH, USA
Ann Neurol 59:796-807. 2006..CONCLUSION: The age-related changes observed in this study provide evidence of increased neuroplasticity of language in this age group and may have implications for further investigations of normal and aberrant language development... - Modified constraint-induced therapy in chronic stroke: results of a single-blinded randomized controlled trialStephen J Page
Department of Rehabilitation Sciences, University of Cincinnati Academic Medical Center, Cincinnati, Ohio, USA
Phys Ther 88:333-40. 2008.... - Human blood genomics: distinct profiles for gender, age and neurofibromatosis type 1Yang Tang
Department of Neurology, University of Cincinnati, Vontz Center, Room 2327, 3125 Eden Avenue, Cincinnati, OH 45267-0536, USA
Brain Res Mol Brain Res 132:155-67. 2004.... - Accuracy of clinical neuropsychological versus statistical prediction in the classification of seizure typesJamison D Fargo
Department of Psychology, Utah State University, UT, USA
Clin Neuropsychol 22:181-94. 2008..Results support the utility and validity of clinical neuropsychological judgment in epilepsy treatment settings... - The prevalence of seizure types among individuals referred for phase I neuropsychological assessment: demographic and neuropsychological characteristicsJamison D Fargo
Department of Psychology, Research and Evaluation Methodology Program, Utah State University, Logan, UT 84322 2810, USA
Clin Neuropsychol 21:442-55. 2007..Considerations for clinical neuropsychological research and practice are briefly discussed... - Mood, personality, and health-related quality of life in epileptic and psychogenic seizure disordersS Marc Testa
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Epilepsia 48:973-82. 2007..ES) can be explained by additional, perhaps chronic, aspects of mood and personality. An understanding of these relationships may inform treatment designed to improve HRQOL in ES or PNES... - Temporal clustering analysis: what does it tell us about the resting state of the brain?Victoria L Morgan
Vanderbilt University Institute of Imaging Science and the Department of Radiology and Radiological Sciences, Vanderbilt University, Nashville, TN, USA
Med Sci Monit 14:CR345-52. 2008....
Research Grants
- EEG-fMRI in Patients with JMEJerzy Szaflarski; Fiscal Year: 2007..Szaflarski is to develop skills necessary to become an independent clinical investigator in the area of neuroimaging in epilepsy, with independent research funding by the time the training is completed. ..
- fMRI of Language Recover Following Stroke in AdultsJerzy Szaflarski; Fiscal Year: 2009....
- fMRI of Language Recover Following Stroke in AdultsJerzy P Szaflarski; Fiscal Year: 2010....