Gerasimos P Sykiotis

Summary

Affiliation: University of Rochester
Country: USA

Publications

  1. ncbi request reprint Of temples and plane trees: the Hippocratic legacy as collective memory
    Gerasimos P Sykiotis
    Department of Biomedical Genetics, University of Rochester Medical Center, Rochester, NY, USA
    Hormones (Athens) 4:55-8. 2005
  2. pmc Stress-activated cap'n'collar transcription factors in aging and human disease
    Gerasimos P Sykiotis
    Department of Biomedical Genetics, University of Rochester Medical Center, Rochester, NY 14642, USA
    Sci Signal 3:re3. 2010
  3. pmc Declining signal dependence of Nrf2-MafS-regulated gene expression correlates with aging phenotypes
    Mohammed Mahidur Rahman
    Department of Biomedical Genetics, University of Rochester Medical Center, Rochester, NY 14642, USA
    Aging Cell 12:554-62. 2013
  4. pmc Genetic activation of Nrf2 signaling is sufficient to ameliorate neurodegenerative phenotypes in a Drosophila model of Parkinson's disease
    Maria Cecilia Barone
    Department of Biomedical Genetics, University of Rochester Medical Center, Rochester, NY 14642, USA
    Dis Model Mech 4:701-7. 2011
  5. pmc Keap1/Nrf2 signaling regulates oxidative stress tolerance and lifespan in Drosophila
    Gerasimos P Sykiotis
    Department of Biomedical Genetics, University of Rochester Medical Center, Rochester, NY 14642, USA
    Dev Cell 14:76-85. 2008
  6. ncbi request reprint Hippocrates and genomic medicine
    Gerasimos P Sykiotis
    Department of Biomedical Genetics, University of Rochester Medical Center, Rochester, NY, USA
    Arch Med Res 37:181-3. 2006
  7. pmc The role of the antioxidant and longevity-promoting Nrf2 pathway in metabolic regulation
    Gerasimos P Sykiotis
    Department of Biomedical Genetics, University of Rochester Medical Center, Rochester, New York, USA
    Curr Opin Clin Nutr Metab Care 14:41-8. 2011
  8. ncbi request reprint Pharmacogenetic principles in the Hippocratic writings
    Gerasimos P Sykiotis
    Department of Biomedical Genetics, University of Rochester Medical Center, New York, USA
    J Clin Pharmacol 45:1218-20. 2005
  9. ncbi request reprint Molecular Medicine and biomedical education: reshaping our mission
    Gerasimos P Sykiotis
    Department of Biomedical Genetics, University of Rochester Medical Center, NY, USA
    Hormones (Athens) 5:87-9. 2006

Collaborators

Detail Information

Publications9

  1. ncbi request reprint Of temples and plane trees: the Hippocratic legacy as collective memory
    Gerasimos P Sykiotis
    Department of Biomedical Genetics, University of Rochester Medical Center, Rochester, NY, USA
    Hormones (Athens) 4:55-8. 2005
  2. pmc Stress-activated cap'n'collar transcription factors in aging and human disease
    Gerasimos P Sykiotis
    Department of Biomedical Genetics, University of Rochester Medical Center, Rochester, NY 14642, USA
    Sci Signal 3:re3. 2010
    ....
  3. pmc Declining signal dependence of Nrf2-MafS-regulated gene expression correlates with aging phenotypes
    Mohammed Mahidur Rahman
    Department of Biomedical Genetics, University of Rochester Medical Center, Rochester, NY 14642, USA
    Aging Cell 12:554-62. 2013
    ..The maintenance of acute stress resistance, motor function, and heart performance in aging flies overexpressing MafS supports a critical role for signal responsiveness of Nrf2 function in promoting youthful phenotypes. ..
  4. pmc Genetic activation of Nrf2 signaling is sufficient to ameliorate neurodegenerative phenotypes in a Drosophila model of Parkinson's disease
    Maria Cecilia Barone
    Department of Biomedical Genetics, University of Rochester Medical Center, Rochester, NY 14642, USA
    Dis Model Mech 4:701-7. 2011
    ..This model provides a genetically accessible in vivo system in which to evaluate the potential of additional Nrf2 pathway components and regulators as therapeutic targets...
  5. pmc Keap1/Nrf2 signaling regulates oxidative stress tolerance and lifespan in Drosophila
    Gerasimos P Sykiotis
    Department of Biomedical Genetics, University of Rochester Medical Center, Rochester, NY 14642, USA
    Dev Cell 14:76-85. 2008
    ..Interestingly, cancer chemopreventive drugs potently stimulate Drosophila Nrf2 activity, suggesting the fruit fly as an experimental system to identify and characterize such agents...
  6. ncbi request reprint Hippocrates and genomic medicine
    Gerasimos P Sykiotis
    Department of Biomedical Genetics, University of Rochester Medical Center, Rochester, NY, USA
    Arch Med Res 37:181-3. 2006
  7. pmc The role of the antioxidant and longevity-promoting Nrf2 pathway in metabolic regulation
    Gerasimos P Sykiotis
    Department of Biomedical Genetics, University of Rochester Medical Center, Rochester, New York, USA
    Curr Opin Clin Nutr Metab Care 14:41-8. 2011
    ....
  8. ncbi request reprint Pharmacogenetic principles in the Hippocratic writings
    Gerasimos P Sykiotis
    Department of Biomedical Genetics, University of Rochester Medical Center, New York, USA
    J Clin Pharmacol 45:1218-20. 2005
    ..This article traces the roots of the emerging personalized and genome-based medicine to the teachings of Hippocrates...
  9. ncbi request reprint Molecular Medicine and biomedical education: reshaping our mission
    Gerasimos P Sykiotis
    Department of Biomedical Genetics, University of Rochester Medical Center, NY, USA
    Hormones (Athens) 5:87-9. 2006