Susan Swindells

Summary

Affiliation: University of Nebraska Medical Center
Country: USA

Publications

  1. ncbi request reprint Predictive value of HIV-1 viral load on risk for opportunistic infection
    Susan Swindells
    University of Nebraska Medical Center, Omaha 68198 5400, USA
    J Acquir Immune Defic Syndr 30:154-8. 2002
  2. pmc Lower CD4 cell count and higher virus load, but not antiretroviral drug resistance, are associated with AIDS-defining events and mortality: an ACTG Longitudinal Linked Randomized Trials (ALLRT) analysis
    Susan Swindells
    University of Nebraska Medical Center, Omaha, NE, USA
    HIV Clin Trials 12:79-88. 2011
  3. pmc New drugs to treat tuberculosis
    Susan Swindells
    University of Nebraska Medical Center, 988106 Nebraska Medical Center Omaha, NE 68198 8106 USA
    F1000 Med Rep 4:12. 2012
  4. pmc Screening for pulmonary tuberculosis in HIV-infected individuals: AIDS Clinical Trials Group Protocol A5253
    S Swindells
    Department of Internal Medicine, University of Nebraska Medical Center, Omaha, Nebraska 68198 8106, USA
    Int J Tuberc Lung Dis 17:532-9. 2013
  5. pmc Abacavir, efavirenz, didanosine, with or without hydroxyurea, in HIV-infected adults failing initial nucleoside/protease inhibitor-containing regimens
    Susan Swindells
    HIV Clinic, University of Nebraska Medical Center, Omaha, NE, USA
    BMC Infect Dis 5:23. 2005
  6. ncbi request reprint Regimen simplification to atazanavir-ritonavir alone as maintenance antiretroviral therapy after sustained virologic suppression
    Susan Swindells
    Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE 68198 5400, USA
    JAMA 296:806-14. 2006
  7. pmc Functional brain abnormalities during finger-tapping in HIV-infected older adults: a magnetoencephalography study
    Tony W Wilson
    Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, 988422 Nebraska Medical Center, Omaha, NE 68198, USA
    J Neuroimmune Pharmacol 8:965-74. 2013
  8. doi request reprint Virologic response, early HIV-1 decay, and maraviroc pharmacokinetics with the nucleos(t)ide-free regimen of maraviroc plus darunavir/ritonavir in a pilot study
    Babafemi Taiwo
    Division of Infectious Diseases, Northwestern University, Chicago, IL Division of Clinical Pharmacology, University of Alabama, Birmingham, AL University of Maryland, Baltimore, MD Statistical and Data Analysis Section, Harvard School of Public Health, Boston, MA Quest Clinical Research, San Francisco, CA Division of Infectious Diseases, University of Miami, Miami, FL CORE Center, Chicago, IL Division of Infectious Diseases, Brigham and Women s Hospital and Harvard Medical School, Boston, MA Division of Infectious Diseases, University of North Carolina, Chapel Hill, NC and Division of Infectious Diseases, University of Nebraska, Omaha, NE
    J Acquir Immune Defic Syndr 64:167-73. 2013
  9. pmc Pilot study of younger and older HIV-infected adults using traditional and novel functional assessments
    Uriel Sandkovsky
    Department of Internal Medicine and Division of Infectious Diseases, University of Nebraska Medical Center, Omaha, NE, USA
    HIV Clin Trials 14:165-74. 2013
  10. pmc Decreased MEG beta oscillations in HIV-infected older adults during the resting state
    Katherine M Becker
    Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, NE, USA
    J Neurovirol 19:586-94. 2013

Detail Information

Publications37

  1. ncbi request reprint Predictive value of HIV-1 viral load on risk for opportunistic infection
    Susan Swindells
    University of Nebraska Medical Center, Omaha 68198 5400, USA
    J Acquir Immune Defic Syndr 30:154-8. 2002
    ....
  2. pmc Lower CD4 cell count and higher virus load, but not antiretroviral drug resistance, are associated with AIDS-defining events and mortality: an ACTG Longitudinal Linked Randomized Trials (ALLRT) analysis
    Susan Swindells
    University of Nebraska Medical Center, Omaha, NE, USA
    HIV Clin Trials 12:79-88. 2011
    ..We hypothesized that drug resistance mutations would impact clinical outcomes associated with HIV-1 infection...
  3. pmc New drugs to treat tuberculosis
    Susan Swindells
    University of Nebraska Medical Center, 988106 Nebraska Medical Center Omaha, NE 68198 8106 USA
    F1000 Med Rep 4:12. 2012
    ..Focusing on treatment for active TB, we review the new pathways to TB regimen development, and the new and repurposed anti-TB agents in clinical development...
  4. pmc Screening for pulmonary tuberculosis in HIV-infected individuals: AIDS Clinical Trials Group Protocol A5253
    S Swindells
    Department of Internal Medicine, University of Nebraska Medical Center, Omaha, Nebraska 68198 8106, USA
    Int J Tuberc Lung Dis 17:532-9. 2013
    ..Improved tuberculosis (TB) screening is urgently needed for human immunodeficiency virus (HIV) infected patients...
  5. pmc Abacavir, efavirenz, didanosine, with or without hydroxyurea, in HIV-infected adults failing initial nucleoside/protease inhibitor-containing regimens
    Susan Swindells
    HIV Clinic, University of Nebraska Medical Center, Omaha, NE, USA
    BMC Infect Dis 5:23. 2005
    ....
  6. ncbi request reprint Regimen simplification to atazanavir-ritonavir alone as maintenance antiretroviral therapy after sustained virologic suppression
    Susan Swindells
    Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE 68198 5400, USA
    JAMA 296:806-14. 2006
    ..Maintenance therapy with ritonavir-boosted atazanavir alone is a possible option because of low pill burden, once-daily dosing, safety, and unique resistance profile...
  7. pmc Functional brain abnormalities during finger-tapping in HIV-infected older adults: a magnetoencephalography study
    Tony W Wilson
    Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, 988422 Nebraska Medical Center, Omaha, NE 68198, USA
    J Neuroimmune Pharmacol 8:965-74. 2013
    ....
  8. doi request reprint Virologic response, early HIV-1 decay, and maraviroc pharmacokinetics with the nucleos(t)ide-free regimen of maraviroc plus darunavir/ritonavir in a pilot study
    Babafemi Taiwo
    Division of Infectious Diseases, Northwestern University, Chicago, IL Division of Clinical Pharmacology, University of Alabama, Birmingham, AL University of Maryland, Baltimore, MD Statistical and Data Analysis Section, Harvard School of Public Health, Boston, MA Quest Clinical Research, San Francisco, CA Division of Infectious Diseases, University of Miami, Miami, FL CORE Center, Chicago, IL Division of Infectious Diseases, Brigham and Women s Hospital and Harvard Medical School, Boston, MA Division of Infectious Diseases, University of North Carolina, Chapel Hill, NC and Division of Infectious Diseases, University of Nebraska, Omaha, NE
    J Acquir Immune Defic Syndr 64:167-73. 2013
    ....
  9. pmc Pilot study of younger and older HIV-infected adults using traditional and novel functional assessments
    Uriel Sandkovsky
    Department of Internal Medicine and Division of Infectious Diseases, University of Nebraska Medical Center, Omaha, NE, USA
    HIV Clin Trials 14:165-74. 2013
    ..Emerging data suggest that HIV disease and its treatment affect the aging process. Accurate and reliable measures of functional status are needed to investigate this further...
  10. pmc Decreased MEG beta oscillations in HIV-infected older adults during the resting state
    Katherine M Becker
    Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, NE, USA
    J Neurovirol 19:586-94. 2013
    ..These findings also suggest that resting-state MEG recordings may hold significant promise as a functional biomarker for identifying HAND and monitoring disease progression...
  11. doi request reprint Measurement of plasma and intracellular concentrations of raltegravir in patients with HIV infection
    Uriel Sandkovsky
    Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE 68198, USA
    AIDS 26:2257-9. 2012
    ..i.d. group. Lower plasma and intracellular concentrations may contribute to inferior virologic suppression rates observed with once daily raltegravir dosing...
  12. ncbi request reprint Development of a rapid autopsy program for studies of brain immunity
    Anuja Ghorpade
    Laboratory of Cellular Neuroimmunology, 985215 Nebraska Medical Center, Omaha, NE, 68198 5215, USA
    J Neuroimmunol 163:135-44. 2005
    ..The challenges in developing this initiative, reflecting experiences from 69 autopsies over 4 years, are presented...
  13. doi request reprint Impact of race/ethnicity on survival among HIV-infected patients in care
    Gregory Lopez
    University of Nebraska Medical Center, USA
    J Health Care Poor Underserved 20:982-95. 2009
    ..To determine the prognostic influence of race/ethnicity on survival among patients infected with HIV infection...
  14. pmc Long-acting parenteral nanoformulated antiretroviral therapy: interest and attitudes of HIV-infected patients
    Jennifer Williams
    Department of Internal Medicine, University of Nebraska Medical Center, 982055 Nebraska Medical Center, Omaha, NE 68198 2055, USA
    Nanomedicine (Lond) 8:1807-13. 2013
    ..To gauge patient interest in receiving long-acting injectable nanoformulated antiretroviral therapy...
  15. pmc The effect of HIV protease inhibitors on amyloid-β peptide degradation and synthesis in human cells and Alzheimer's disease animal model
    Xiqian Lan
    Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, NE 68198 5880, USA
    J Neuroimmune Pharmacol 7:412-23. 2012
    ..These data demonstrated that ART drugs can inhibit Aβ clearance in macrophages and Aβ production in neurons, but these effects did not significantly alter Aβ accumulation in the mouse brain...
  16. pmc Clinical evaluation of a dried blood spot assay for atazanavir
    Trevor Van Schooneveld
    Department of Internal Medicine, Section of Infectious Diseases, University of Nebraska Medical Center, Nebraska Medical Center, Omaha, NE 68198 4031, USA
    Antimicrob Agents Chemother 54:4124-8. 2010
    ..DBS use offers a convenient alternative for measuring plasma concentrations of ATV and may have utility in monitoring of drug concentrations in clinical practice and in future studies...
  17. ncbi request reprint Clinical utility of interferon gamma assay in the diagnosis of tuberculosis
    Miguel G Madariaga
    HIV Clinic, Section of Infectious Diseases, University of Nebraska Medical Center, Omaha NE 68198, USA
    J Am Board Fam Med 20:540-7. 2007
    ..This study discusses the potential benefits and drawbacks in patients, including those who are immunocompromised...
  18. pmc Acceptable plasma concentrations of raltegravir and etravirine when administered by gastrostomy tube in a patient with advanced multidrug-resistant human immunodeficiency virus infection
    Uriel Sandkovsky
    Division of Infectious Diseases, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, Nebraska 68198 8106, USA
    Pharmacotherapy 32:142-7. 2012
    ..To determine whether the absorption of four antiretroviral agents-raltegravir, etravirine, emtricitabine, and tenofovir-is compromised when administered by gastrostomy tube...
  19. ncbi request reprint Racial/ethnic differences in CD4 T cell count and viral load at presentation for medical care and in follow-up after HIV-1 infection
    Susan Swindells
    Department of Internal Medicine, Universitsity of Nebraska Medical Center, Omaha, NE, USA
    AIDS 16:1832-4. 2002
    ..08), who were also more likely to present with major opportunistic infections (P < 0.004). Once in care, changes in CD4 T cell counts and viral loads over time did not differ significantly between groups...
  20. pmc Tuberculosis immune reconstitution inflammatory syndrome in A5221 STRIDE: timing, severity, and implications for HIV-TB programs
    Anne F Luetkemeyer
    HIV AIDS Division, San Francisco General Hospital, University of California, San Francisco, CA Center for Biostatistics in AIDS Research, Harvard School of Public Health, Boston, MA Department of Medicine, College of Medicine, Blantyre, Malawi Faculty of Heath Sciences, University of the Witwatersrand, Johannesburg, South Africa Division of Infectious Diseases, School of Medicine, University of California, San Diego, CA and Division of Infectious Diseases, University of Nebraska Medical Center, Omaha, NE
    J Acquir Immune Defic Syndr 65:423-8. 2014
    ..later ART (8-12 weeks after TB treatment) in HIV-infected patients starting TB treatment...
  21. pmc Abnormal MEG oscillatory activity during visual processing in the prefrontal cortices and frontal eye-fields of the aging HIV brain
    Tony W Wilson
    Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, Nebraska, USA
    PLoS ONE 8:e66241. 2013
    ..Previous neuroimaging studies have shown greater activation in HIV-infected patients during strenuous tasks in frontal and parietal cortices, and less activation in the primary sensory cortices during rest and sensory stimulation...
  22. ncbi request reprint Neuroinflammatory responses from microglia recovered from HIV-1-infected and seronegative subjects
    Anuja Ghorpade
    Laboratory of Cellular Neuroimmunology, 985215 Nebraska Medical Center, Omaha, NE, 68198 5215, USA
    J Neuroimmunol 163:145-56. 2005
    ..Monocytes from seronegative donors paralleled these diminished immune responses following repeated LPS-activation. These results demonstrate changes in innate microglial function following viral infection or chronic immune activation...
  23. doi request reprint Antiretroviral medication prescribing errors are common with hospitalization of HIV-infected patients
    Tessa Commers
    Department of Internal Medicine and Division of Infectious Diseases, University of Nebraska Medical Center, Omaha, NE, USA
    J Antimicrob Chemother 69:262-7. 2014
    ..Errors in prescribing antiretroviral therapy (ART) often occur with the hospitalization of HIV-infected patients. The rapid identification and prevention of errors may reduce patient harm and healthcare-associated costs...
  24. ncbi request reprint Malacoplakia of the cranium and cerebrum in a human immunodeficiency virus-infected man. Case report
    Edna Toubes-Klingler
    Department of Internal Medicine Section of Infectious Diseases, University of Nebraska Medical Center, Omaha, Nebraska 68198 5400, USA
    J Neurosurg 104:432-5. 2006
    ..A complete resection of the lesion, antibiotic therapy, and treatment of his underlying HIV infection had a salutary effect, with the patient faring well more than 9 months postoperatively...
  25. doi request reprint Extensively drug-resistant tuberculosis
    Miguel G Madariaga
    Section of Infectious Diseases, University of Nebraska Medical Center, Omaha, NE 68198 8106, USA
    Am J Med 121:835-44. 2008
    ..Infection control measures do not differ from those used for susceptible cases but may require more stringent application...
  26. ncbi request reprint HIV education needs among Sudanese immigrants and refugees in the Midwestern United States
    Marc Tompkins
    College of Medicine, University of Nebraska Medical Center, Omaha, Nebraska 68198 5400, USA
    AIDS Behav 10:319-23. 2006
    ..Appropriate educational materials are lacking, and there is a pressing need for improved access to culturally appropriate HIV education for this vulnerable population...
  27. ncbi request reprint Randomized controlled study of tenofovir and adefovir in chronic hepatitis B virus and HIV infection: ACTG A5127
    Marion G Peters
    University of California, San Francisco, San Francisco, CA, USA
    Hepatology 44:1110-6. 2006
    ..In conclusion, over 48 weeks, treatment with either ADV or TDF resulted in clinically important suppression of serum HBV DNA. Both drugs are safe and efficacious for patients coinfected with HBV and HIV...
  28. pmc Potential risks and benefits of HIV treatment simplification: a simulation model of a proposed clinical trial
    Bruce R Schackman
    Department of Public Health, Weill Cornell Medical College, New York, NY 10021, USA
    Clin Infect Dis 45:1062-70. 2007
    ..We projected the long-term outcomes of this treatment simplification strategy to inform the design of a proposed multicenter, randomized clinical trial...
  29. doi request reprint Subgroup analyses of maraviroc in previously treated R5 HIV-1 infection
    Gerd Fatkenheuer
    Universitätsklinik Köln, Cologne, Germany
    N Engl J Med 359:1442-55. 2008
    ....
  30. pmc Class-sparing regimens for initial treatment of HIV-1 infection
    Sharon A Riddler
    University of Pittsburgh, Pittsburgh, USA
    N Engl J Med 358:2095-106. 2008
    ..The alternative regimen of lopinavir-ritonavir plus efavirenz may prevent toxic effects associated with NRTIs...
  31. pmc Maraviroc for previously treated patients with R5 HIV-1 infection
    Roy M Gulick
    Weill Cornell Medical College, New York, NY 10065, USA
    N Engl J Med 359:1429-41. 2008
    ..CC chemokine receptor 5 antagonists are a new class of antiretroviral agents...
  32. ncbi request reprint Alendronate with calcium and vitamin D supplementation is safe and effective for the treatment of decreased bone mineral density in HIV
    Grace A McComsey
    Rainbow Babies and Children s Hospital and Case Western Reserve University, Cleveland, Ohio, USA
    AIDS 21:2473-82. 2007
    ..Bisphosphonates are currently the mainstay of treatment for postmenopausal and male osteoporosis in HIV-uninfected individuals; however, their efficacy and safety in HIV-infected patients remains unclear...
  33. ncbi request reprint Fragility fractures in HIV-infected patients: need for better understanding of diagnosis and management
    Grace A McComsey
    Case Western Reserve University, Cleveland, OH, USA
    J Int Assoc Physicians AIDS Care (Chic) 3:86-91. 2004
    ..In HIV and ART, osteopenia and osteoporosis are multifactorial, and health promotion or medical health maintenance should anticipate and prevent morbidity of bone fragility fractures...
  34. pmc Oxazolidinones and human immunodeficiency virus
    Miguel G Madariaga
    Antimicrob Agents Chemother 51:1130; author reply 1130. 2007
  35. ncbi request reprint Discrepant results of 2 screening tests for anti-HIV antibody
    Douglas F Stickle
    Clin Infect Dis 35:773-4; author reply 774-5. 2002
  36. ncbi request reprint Stabilization of white blood cells and immunologic markers for extended analysis using flow cytometry
    Dominic E Warrino
    Streck, 7002 S 109th Street, Omaha, NE 68128, United States
    J Immunol Methods 305:107-19. 2005
    ..96 or greater) from samples collected in K3EDTA tubes and tested at 6 h. We conclude that whole blood samples collected in Cyto-Chex BCT are stabilized for their marker phenotype for at least 7 days after phlebotomy...
  37. ncbi request reprint HIV-1-associated dementia: a basic science and clinical perspective
    Thomas S Diesing
    Department of Neurology, Mayo Clinic, Rochester, Minnesota, USA
    AIDS Read 12:358-68. 2002
    ..Improvements in antiretroviral and adjunctive therapies have decreased HAD incidence, but cognitive dysfunction remains a cause of morbidity in many infected persons...