Steven H Swerdlow

Summary

Affiliation: University of Pittsburgh
Country: USA

Publications

  1. pmc Follicular lymphoma-like B cells of uncertain significance (in situ follicular lymphoma) may infrequently progress, but precedes follicular lymphoma, is associated with other overt lymphomas and mimics follicular lymphoma in flow cytometric studies
    Raju K Pillai
    Haematologica 98:1571-80. 2013
  2. doi request reprint Cutaneous B-cell lymphoproliferative disorders: report of the 2011 Society for Hematopathology/European Association for Haematopathology workshop
    Steven H Swerdlow
    Division of Hematopathology, UPMC Health System UPMC Presbyterian, 200 Lothrop St, Room G 335, Pittsburgh, PA 15213 2582, USA
    Am J Clin Pathol 139:515-35. 2013
  3. doi request reprint Lymphoma classification and the tools of our trade: an introduction to the 2012 USCAP Long Course
    Steven H Swerdlow
    Division of Hematopathology, Department of Pathology, UPMC Health System UPMC Presbyterian, University of Pittsburgh School of Medicine, 200 Lothrop Street, Pittsburgh, PA 15213, USA
    Mod Pathol 26:S1-S14. 2013
  4. ncbi request reprint Clinicopathologic, immunophenotypic, and molecular cytogenetic fluorescence in situ hybridization analysis of primary and secondary cutaneous follicular lymphomas
    Bong K Kim
    Department of Pathology, Division of Hematopathology, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Am J Surg Pathol 29:69-82. 2005
  5. doi request reprint Follicular lymphomas with plasmacytic differentiation include two subtypes
    Joel F Gradowski
    Division of Hematopathology, Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    Mod Pathol 23:71-9. 2010
  6. doi request reprint Splenic lymphoid subsets with less well-recognized phenotypes mimic aberrant antigen expression
    Nidhi Aggarwal
    Division of Hematopathology, Department of Pathology, University of Pittsburgh School of Medicine, 200 Lothrop St, Suite G300, Pittsburgh, PA 15213 2582
    Am J Clin Pathol 140:787-94. 2013
  7. pmc Natural killer cell subsets and natural killer-like T-cell populations in benign and neoplastic B-cell proliferations vary based on clinicopathologic features
    Sarah E Gibson
    Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    Hum Pathol 42:679-87. 2011
  8. ncbi request reprint T(14;18)(q32;q21) involving MALT1 and IGH genes in an extranodal diffuse large B-cell lymphoma
    James R Cook
    Department of Pathology, University of Pittsburgh School of Medicine, PA 15213, USA
    Hum Pathol 34:1212-5. 2003
  9. ncbi request reprint Benign CD10-positive T cells in reactive lymphoid proliferations and B-cell lymphomas
    James R Cook
    Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    Mod Pathol 16:879-85. 2003
  10. doi request reprint Whole-genome single nucleotide polymorphism array analysis is complementary to classical cytogenetic analysis in the evaluation of lymphoid proliferations
    Sarah E Gibson
    UPMC Presbyterian Hospital, Room G 314, 200 Lothrop St, Pittsburgh, PA 15213 E mail
    Am J Clin Pathol 141:247-55. 2014

Collaborators

Detail Information

Publications48

  1. pmc Follicular lymphoma-like B cells of uncertain significance (in situ follicular lymphoma) may infrequently progress, but precedes follicular lymphoma, is associated with other overt lymphomas and mimics follicular lymphoma in flow cytometric studies
    Raju K Pillai
    Haematologica 98:1571-80. 2013
    ..Flow cytometric studies demonstrating follicular lymphoma-like B cells must not be over-interpreted as they may only reflect follicular lymphoma-like B cells. ..
  2. doi request reprint Cutaneous B-cell lymphoproliferative disorders: report of the 2011 Society for Hematopathology/European Association for Haematopathology workshop
    Steven H Swerdlow
    Division of Hematopathology, UPMC Health System UPMC Presbyterian, 200 Lothrop St, Room G 335, Pittsburgh, PA 15213 2582, USA
    Am J Clin Pathol 139:515-35. 2013
    ..Iatrogenic and senescent immunodeficiency-associated lymphoproliferative disorders that are often Epstein-Barr virus (EBV) positive can also primarily involve the skin, including cases also known as EBV-positive mucocutaneous ulcer...
  3. doi request reprint Lymphoma classification and the tools of our trade: an introduction to the 2012 USCAP Long Course
    Steven H Swerdlow
    Division of Hematopathology, Department of Pathology, UPMC Health System UPMC Presbyterian, University of Pittsburgh School of Medicine, 200 Lothrop Street, Pittsburgh, PA 15213, USA
    Mod Pathol 26:S1-S14. 2013
    ..Finally, one must not forget the great importance of clinical data in arriving at a diagnosis that best serves the patient, our ultimate goal...
  4. ncbi request reprint Clinicopathologic, immunophenotypic, and molecular cytogenetic fluorescence in situ hybridization analysis of primary and secondary cutaneous follicular lymphomas
    Bong K Kim
    Department of Pathology, Division of Hematopathology, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Am J Surg Pathol 29:69-82. 2005
    ..These findings suggest that primary cutaneous FL are distinctive and often but not always have a pathogenesis different from most of nodal and secondary cutaneous FL...
  5. doi request reprint Follicular lymphomas with plasmacytic differentiation include two subtypes
    Joel F Gradowski
    Division of Hematopathology, Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    Mod Pathol 23:71-9. 2010
    ....
  6. doi request reprint Splenic lymphoid subsets with less well-recognized phenotypes mimic aberrant antigen expression
    Nidhi Aggarwal
    Division of Hematopathology, Department of Pathology, University of Pittsburgh School of Medicine, 200 Lothrop St, Suite G300, Pittsburgh, PA 15213 2582
    Am J Clin Pathol 140:787-94. 2013
    ..Flow cytometry can assist in the diagnosis of lymphoma by identifying aberrant antigen expression. Recognition of aberrancy requires knowledge of the phenotype of normal lymphoid cells...
  7. pmc Natural killer cell subsets and natural killer-like T-cell populations in benign and neoplastic B-cell proliferations vary based on clinicopathologic features
    Sarah E Gibson
    Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    Hum Pathol 42:679-87. 2011
    ..This may be of importance with increasing therapeutic use of immunomodulatory agents...
  8. ncbi request reprint T(14;18)(q32;q21) involving MALT1 and IGH genes in an extranodal diffuse large B-cell lymphoma
    James R Cook
    Department of Pathology, University of Pittsburgh School of Medicine, PA 15213, USA
    Hum Pathol 34:1212-5. 2003
    ....
  9. ncbi request reprint Benign CD10-positive T cells in reactive lymphoid proliferations and B-cell lymphomas
    James R Cook
    Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    Mod Pathol 16:879-85. 2003
    ..These findings indicate that a normal small subset of CD10+ peripheral T cells exists and, at least when present in small numbers, should not be considered an indication of a T-cell neoplasm...
  10. doi request reprint Whole-genome single nucleotide polymorphism array analysis is complementary to classical cytogenetic analysis in the evaluation of lymphoid proliferations
    Sarah E Gibson
    UPMC Presbyterian Hospital, Room G 314, 200 Lothrop St, Pittsburgh, PA 15213 E mail
    Am J Clin Pathol 141:247-55. 2014
    ..To explore how much additional information single nucleotide polymorphism (SNP) arrays provide and whether they could partially replace classical cytogenetics...
  11. doi request reprint Fluorescence immunophenotypic and interphase cytogenetic characterization of nodal lymphoplasmacytic lymphoma
    Rachel Lynn Sargent
    Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    Am J Surg Pathol 32:1643-53. 2008
    ..The search for better objective inclusionary criteria for LPL must continue...
  12. ncbi request reprint Analysis of immunoglobulin V genes suggests cutaneous marginal zone B-cell lymphomas recognise similar antigens
    David W Bahler
    Department of Pathology, University of Utah Medical Center, Salt Lake City, UT 84132, USA
    Br J Haematol 132:571-5. 2006
    ..Analysis of the somatic mutations present in many of the V(H) genes was also consistent with antigen directly stimulating the growth of cutaneous EMZL...
  13. pmc Defining the borders of splenic marginal zone lymphoma: a multiparameter study
    Scott D Dufresne
    Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    Hum Pathol 41:540-51. 2010
    ..They also demonstrate a relatively large proportion of unclassifiable cases, including a group with frequent +12...
  14. doi request reprint EBV-positive extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue in the posttransplant setting: a distinct type of posttransplant lymphoproliferative disorder?
    Sarah E Gibson
    Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA
    Am J Surg Pathol 35:807-15. 2011
    ..Whether their distinctive subcutaneous/soft tissue localization and IgA positivity are uniform features will require identification of additional cases...
  15. pmc CD30 expression and proliferative fraction in nontransformed mycosis fungoides
    James T Edinger
    Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Am J Surg Pathol 33:1860-8. 2009
    ..Therefore, CD30 expression is not restricted to transformed MF but higher levels of dermal CD30 expression and, even more so, dermal Ki-67 levels are independent adverse prognostic indicators...
  16. pmc Thyroid carcinoma-associated genetic mutations also occur in thyroid lymphomas
    Nidhi Aggarwal
    Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Mod Pathol 25:1203-11. 2012
    ....
  17. doi request reprint Human Merkel cell polyomavirus infection I. MCV T antigen expression in Merkel cell carcinoma, lymphoid tissues and lymphoid tumors
    Masahiro Shuda
    Molecular Virology Program, University of Pittsburgh Cancer Institute, Pittsburgh, PA 15213, USA
    Int J Cancer 125:1243-9. 2009
    ..As with some of the other human polyomaviruses, lymphocytes may serve as a tissue reservoir for MCV infection, but hematolymphoid malignancies associated with MCC are unlikely to be caused by MCV...
  18. doi request reprint Double-hit B-cell lymphomas with BCL6 and MYC translocations are aggressive, frequently extranodal lymphomas distinct from BCL2 double-hit B-cell lymphomas
    Raju K Pillai
    Department of Pathology, Division of Hematopathology, Magee Womens Hospital, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Am J Surg Pathol 37:323-32. 2013
    ..Unlike DH-BCL2/MYC lymphomas, however, they are more likely to be CD10(-) but IRF4/MUM-1(+) (P=0.03) and, more like BL, only infrequently express BCL2 (P<0.001), and are cytogenetically less complex (P<0.04)...
  19. pmc Use of similar immunoglobulin VH gene segments by MALT lymphomas of the ocular adnexa
    David W Bahler
    Department of Pathology, University of Utah, Salt Lake City, UT 84112, USA
    Mod Pathol 22:833-8. 2009
    ..Analysis of somatic mutations present within the VH genes is also consistent with antigen binding stimulating the growth of these lymphomas...
  20. ncbi request reprint Abnormal patterns of antigenic expression in follicular lymphoma: a flow cytometric study
    Sourav Ray
    Department of Pathology, Division of Hematopathology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    Am J Clin Pathol 124:576-83. 2005
    ..These findings expand the ways in which FC studies can be used to help diagnose FL and suggest that the phenotypic aberrations identified do not represent normal developmental pathways...
  21. ncbi request reprint Splenic small B-cell lymphoma with IGH/BCL3 translocation
    Lorinda A Soma
    Division of Hematopathology, University of Pittsburgh School of Medicine, PA 15213, USA
    Hum Pathol 37:218-30. 2006
    ..This case suggests that the IGH/BCL3 translocation may help to define a new clinicopathologic entity...
  22. pmc Reassessment of small lymphocytic lymphoma in the era of monoclonal B-cell lymphocytosis
    Sarah E Gibson
    Department of Pathology, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA
    Haematologica 96:1144-52. 2011
    ..Minimal criteria of tissue involvement to separate small lymphocytic lymphoma from monoclonal B-cell lymphocytosis have not been defined...
  23. pmc Nodal aggressive B-cell lymphomas: a diagnostic approach
    Sonam Prakash
    Division of Hematopathology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    J Clin Pathol 60:1076-85. 2007
    ..Whereas the diagnosis of some cases will be relatively easy, the differential diagnosis in others is very difficult, with some cases in a grey zone between two different well defined categories...
  24. pmc Chronic lymphocytic leukemia/small lymphocytic lymphoma with cyclin D1 positive proliferation centers do not have CCND1 translocations or gains and lack SOX11 expression
    Joel F Gradowski
    Division of Hematopathology, Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    Am J Clin Pathol 138:132-9. 2012
    ..The recognition of cyclin D1 expression in PC of a significant minority of CLL/SLL can be a diagnostic aid and should not lead to the diagnosis of focal mantle cell lymphoma...
  25. doi request reprint Cytogenetic abnormalities detected by fluorescence in situ hybridization on paraffin-embedded chronic lymphocytic leukemia/small lymphocytic lymphoma lymphoid tissue biopsy specimens
    Melina B Flanagan
    Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Am J Clin Pathol 130:620-7. 2008
    ..3 in combination with other aberrations. Cytogenetic FISH studies using paraffin-embedded tissue biopsy specimens in CLL/SLL had a high yield and, with 1 exception, demonstrated a profile similar to cases diagnosed in PB/BM...
  26. doi request reprint Best practices in contemporary diagnostic immunohistochemistry: panel approach to hematolymphoid proliferations
    Christine F Garcia
    Department of Pathology, University of Pittsburgh School of Medicine, Pennsylvania, USA
    Arch Pathol Lab Med 133:756-65. 2009
    ..It then becomes a challenge knowing the best approach to the selection of antibodies to use and how to interpret them...
  27. ncbi request reprint Gene expression profiling of Epstein-Barr virus-positive and -negative monomorphic B-cell posttransplant lymphoproliferative disorders
    Fiona E Craig
    Division of Hematopathology, Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Diagn Mol Pathol 16:158-68. 2007
    ..By contrast, EBV- PTLD lacked viral-associated changes suggesting that they are biologically distinct...
  28. ncbi request reprint Indolent mantle cell lymphoma with nodal involvement and mutated immunoglobulin heavy chain genes
    Laurentia Nodit
    Department of Pathology, University of Pittsburgh School of Medicine, PA, USA
    Hum Pathol 34:1030-4. 2003
    ..The subtle but diagnostic lymph node biopsy in this case helps to further support that an indolent t(11;14) monoclonal lymphocytosis with mutated Ig genes can represent an MCL variant rather than chronic lymphocytic leukemia...
  29. ncbi request reprint Derivative (14)t(11;14)(q13;q32)t(11;14)(p11.2;p11.2): a novel unbalanced variant of the t(11;14)(q13;q32) translocation in mantle cell lymphoma
    Malini Sathanoori
    Pittsburgh Cytogenetics Laboratory, Magee Womens Hospital, University of Pittsburgh Medical Center Health System, 300 Halket Street, Pittsburgh, PA 15213, USA
    Cancer Genet Cytogenet 172:158-64. 2007
    ..This chromosome was designated as der(14)t(11;14)(q13;q32)t(11;14)(p11.1;p11.2)...
  30. doi request reprint ZAP-70 and Bcl-2 expression in B lymphoblastic leukemia cells and hematogones
    Fiona E Craig
    Division of Hematopathology, Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    Cytometry B Clin Cytom 82:85-92. 2012
    ..However, the search continues for an optimal reagent set that can identify leukemic blasts with specificity, reproducibility, and sensitivity, at any point during the course of the disease and in every specimen type...
  31. ncbi request reprint The proliferation center microenvironment and prognostic markers in chronic lymphocytic leukemia/small lymphocytic lymphoma
    Lorinda A Soma
    Division of Hematopathology, University of Pittsburgh School of Medicine, PA 15213 2582, USA
    Hum Pathol 37:152-9. 2006
    ..They support the hypothesis that PCs are a site for B-cell receptor signaling, which helps explain reported site-dependent antigenic variation in CLL/SLL, and suggest that PC morphology may correlate with other biological features...
  32. doi request reprint Flow cytometric immunophenotyping of cerebrospinal fluid specimens
    Fiona E Craig
    Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    Am J Clin Pathol 135:22-34. 2011
    ..FCI may be of value in low-cellularity CSF specimens, although the results should be interpreted with caution...
  33. ncbi request reprint Simultaneous detection of imprinted gene expression (p57(KIP2)) and molecular cytogenetics (FICTION) in the evaluation of molar pregnancies
    Lori Hoffner
    Magee Women s Research Institute, Pittsburgh, PA 15213, USA
    J Reprod Med 55:219-28. 2010
    ..To simultaneously evaluate the p57(KIP2) antibody expression and genotype of individual cells from paraffin sections of molar pregnancies...
  34. ncbi request reprint Pediatric follicular lymphomas, marginal zone lymphomas, and marginal zone hyperplasia
    Steven H Swerdlow
    Department of Pathology, University of Pittsburgh School of Medicine, PA 15213, USA
    Am J Clin Pathol 122:S98-109. 2004
    ..Understanding the full spectrum of B-cell neoplasia in children and its unique features is important for diagnostic, therapeutic, and academic purposes...
  35. pmc Intestinal γδ T-cell lymphomas are most frequently of type II enteropathy-associated T-cell type
    Amanda L Wilson
    University of Pittsburgh, Pittsburgh, PA 15213, USA
    Hum Pathol 44:1131-45. 2013
    ..These findings support the conclusion that a γδ T-cell origin at extracutaneous sites does not define a specific entity...
  36. doi request reprint Primary cutaneous marginal zone lymphoma with subclinical cutaneous involvement and biclonality
    James T Edinger
    Division of Hematopathology, Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    J Cutan Pathol 38:724-30. 2011
    ..This case represents a newly described clinical appearance of primary cutaneous MZL and shows that some patients may have more than one neoplastic clone...
  37. pmc Molecular characteristics of mantle cell lymphoma presenting with clonal plasma cell component
    Carlo Visco
    Department of Pathology, University of Wisconsin School of Medicine and Public Health, Madison, USA
    Am J Surg Pathol 35:177-89. 2011
    ..Our findings suggest that MCL can present with a PC component that is often clonally related to the lymphoma, representing a rare but unique biological variant of this tumor...
  38. doi request reprint Phase II trial of short-course CHOP-R followed by 90Y-ibritumomab tiuxetan and extended rituximab in previously untreated follicular lymphoma
    Samuel A Jacobs
    Department of Medicine, University of Pittsburgh Medical Center Cancer Centers, Pittsburgh, Pennsylvania 15232, USA
    Clin Cancer Res 14:7088-94. 2008
    ....
  39. doi request reprint The number and growth pattern of plasmacytoid dendritic cells vary in different types of reactive lymph nodes: an immunohistochemical study
    Marian A Rollins-Raval
    Department of Pathology, Division of Hematopathology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    Hum Pathol 44:1003-10. 2013
    ..However, tight aggregates were a characteristic feature of hyaline-vascular Castleman disease, and viral infections typically showed only few scattered cells distributed singly...
  40. doi request reprint Cutaneous marginal zone lymphomas have distinctive features and include 2 subsets
    James T Edinger
    Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Am J Surg Pathol 34:1830-41. 2010
    ....
  41. ncbi request reprint Utility of CD279/PD-1 Immunohistochemistry in the Evaluation of Benign and Neoplastic T-Cell-Rich Bone Marrow Infiltrates
    Christopher H Cogbill
    From the Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA
    Am J Clin Pathol 142:88-98. 2014
    ....
  42. ncbi request reprint Nodal marginal zone B-cell lymphoma with a novel t(X;5)(q28;q22): conventional and molecular cytogenetic analysis
    James R Cook
    Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Cancer Genet Cytogenet 143:154-9. 2003
    ..This translocation has not been previously reported in the literature...
  43. ncbi request reprint Genetic and molecular genetic studies in the diagnosis of atypical lymphoid hyperplasias versus lymphoma
    Steven H Swerdlow
    Division of Hematopathology, University of Pittsburgh Health System, Pittsburgh, PA 15213 2582, USA
    Hum Pathol 34:346-51. 2003
  44. ncbi request reprint Primary and secondary cutaneous diffuse large B-cell lymphomas: a multiparameter analysis of 25 cases including fluorescence in situ hybridization for t(14;18) translocation
    Bong K Kim
    Department of Pathology, Division of Hematopathology, University of Pittsburgh School of Medicine, 200 Lothrop Street, Pittsburgh, PA 15213, USA
    Am J Surg Pathol 27:356-64. 2003
    ..Nevertheless, some appear to be of follicular center cell origin, even though they probably have a different molecular pathogenesis than most nodal follicular lymphomas...
  45. ncbi request reprint T-cell and NK-cell posttransplantation lymphoproliferative disorders
    Steven H Swerdlow
    Department of Pathology, Division of Hematopathology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    Am J Clin Pathol 127:887-95. 2007
    ..Many T/NK-cell PTLDs have been treated with chemotherapy, often together with decreased immunosuppression, but there are infrequent patients who have done well without chemotherapy or radiation...
  46. doi request reprint B-Cell lymphoproliferative disorder of an ICD pocket: a diagnostic puzzle in an immunosuppressed patient
    Jan Nemec
    Cardiovascular Institute, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Pacing Clin Electrophysiol 31:769-71. 2008
    ..We present a case of a patient with lymphoma in an ICD pocket in the setting of posttransplant immune suppression. Infection of the ICD system was suspected and the correct diagnosis was established by biopsy...
  47. pmc Comparison of Bcl-2, CD38 and ZAP-70 Expression in Chronic Lymphocytic Leukemia
    Rachel L Sargent
    Department of Pathology, Division of Hematopathology, University of Pittsburgh School of Medicine Pittsburgh, PA
    Int J Clin Exp Pathol 2:574-82. 2009
    ..004, r(2)=0.27) samples were analyzed. While bcl-2 levels do not appear to be a major discriminator between indolent and more aggressive subtypes of CLL, CD38 and bcl-2 expression appear to be interrelated...
  48. pmc Pulmonary extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue associated with granulomatous inflammation in a child with chromosome 22q11.2 deletion syndrome (DiGeorge syndrome)
    Tawatchai Pongpruttipan
    Division of Hematopathology, Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    J Pediatr 161:954-8. 2012
    ..2 deletion syndrome have been reported. We report a case of a pulmonary Epstein-Barr virus-negative extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue in a child with this syndrome...