E R Swenson

Summary

Affiliation: University of Washington
Country: USA

Publications

  1. ncbi request reprint Nitric oxide (NO) in normal and hypoxic vascular regulation of the spiny dogfish, Squalus acanthias
    Kai E Swenson
    Mt Desert Island Biological Laboratory, Salsbury Cove, Maine 04672, USA
    J Exp Zool A Comp Exp Biol 303:154-60. 2005
  2. ncbi request reprint Carbonic anhydrase inhibitors and high altitude illnesses
    Erik R Swenson
    VA Puget Sound Health Care System and Department of Medicine, University of Washington, Seattle, WA, USA
    Subcell Biochem 75:361-86. 2014
  3. doi request reprint Hypoxic pulmonary vasoconstriction
    Erik R Swenson
    Department of Medicine, University of Washington, VA Puget Sound Health Care System, Seattle, WA 98108, USA
    High Alt Med Biol 14:101-10. 2013
  4. doi request reprint High-altitude pulmonary edema
    Erik R Swenson
    VA Puget Sound Health Care System, Department of Medicine, University of Washington, Seattle, Washington, USA
    Compr Physiol 2:2753-73. 2012
  5. doi request reprint Anemia in critical illness: insights into etiology, consequences, and management
    Shailaja J Hayden
    Division of Pulmonary and Critical Care Medicine, University of Washington, Seattle, Washington, USA
    Am J Respir Crit Care Med 185:1049-57. 2012
  6. ncbi request reprint Biochemical, histological, and inhibitor studies of membrane carbonic anhydrase in frog gastric acid secretion
    E R Swenson
    Department of Medicine, Department of Veterans Affairs Medical Center, University of Washington, Seattle, Washington 98108, USA
    Am J Physiol Gastrointest Liver Physiol 281:G61-8. 2001
  7. ncbi request reprint Metabolic acidosis
    E R Swenson
    School of Medicine, University of Washington, Seattle, USA
    Respir Care 46:342-53. 2001
  8. ncbi request reprint 14th International Hypoxia Symposium, February 23-27, 2005, Chateau Lake Louise, Alberta, Canada
    Erik R Swenson
    Pulmonary Section 111 B, Department of Medicine, University of Washington, Veterans Administration Medical Center, 1660 S Columbian Way, Seattle, WA 98108 1597, USA
    High Alt Med Biol 6:181-8. 2005
  9. ncbi request reprint Pathogenesis of high-altitude pulmonary edema: inflammation is not an etiologic factor
    Erik R Swenson
    Pulmonary and Critical Care Section, S 111 Pulm, Veterans Affairs Puget Sound Health Care System, 1660 S Columbian Way, Seattle, WA 98108, USA
    JAMA 287:2228-35. 2002
  10. ncbi request reprint Inhibition of aquaporin-mediated CO2 diffusion and voltage-gated H+ channels by zinc does not alter rabbit lung CO2 and NO excretion
    Erik R Swenson
    Department of Medicine, VA Puget Sound Health Care System, University of Washington, Seattle, WA 98108, USA
    Clin Sci (Lond) 103:567-75. 2002

Collaborators

Detail Information

Publications67

  1. ncbi request reprint Nitric oxide (NO) in normal and hypoxic vascular regulation of the spiny dogfish, Squalus acanthias
    Kai E Swenson
    Mt Desert Island Biological Laboratory, Salsbury Cove, Maine 04672, USA
    J Exp Zool A Comp Exp Biol 303:154-60. 2005
    ..In acute hypoxia, there is a rapid up-regulation of vascular NO production that appears to be responsible for hypoxic vasodilation...
  2. ncbi request reprint Carbonic anhydrase inhibitors and high altitude illnesses
    Erik R Swenson
    VA Puget Sound Health Care System and Department of Medicine, University of Washington, Seattle, WA, USA
    Subcell Biochem 75:361-86. 2014
    ....
  3. doi request reprint Hypoxic pulmonary vasoconstriction
    Erik R Swenson
    Department of Medicine, University of Washington, VA Puget Sound Health Care System, Seattle, WA 98108, USA
    High Alt Med Biol 14:101-10. 2013
    ..This review will provide a broad overview of HPV and its mechansms and discuss the advantages and disadvantages of HPV in normal physiology, disease and high altitude...
  4. doi request reprint High-altitude pulmonary edema
    Erik R Swenson
    VA Puget Sound Health Care System, Department of Medicine, University of Washington, Seattle, Washington, USA
    Compr Physiol 2:2753-73. 2012
    ....
  5. doi request reprint Anemia in critical illness: insights into etiology, consequences, and management
    Shailaja J Hayden
    Division of Pulmonary and Critical Care Medicine, University of Washington, Seattle, Washington, USA
    Am J Respir Crit Care Med 185:1049-57. 2012
    ....
  6. ncbi request reprint Biochemical, histological, and inhibitor studies of membrane carbonic anhydrase in frog gastric acid secretion
    E R Swenson
    Department of Medicine, Department of Veterans Affairs Medical Center, University of Washington, Seattle, Washington 98108, USA
    Am J Physiol Gastrointest Liver Physiol 281:G61-8. 2001
    ....
  7. ncbi request reprint Metabolic acidosis
    E R Swenson
    School of Medicine, University of Washington, Seattle, USA
    Respir Care 46:342-53. 2001
    ..Theoretical and clinical evidence are discussed for alkalinizing agents, whose use remains controversial except in the treatment of metabolic acidosis associated with hyperkalemia and certain drug or toxin ingestions...
  8. ncbi request reprint 14th International Hypoxia Symposium, February 23-27, 2005, Chateau Lake Louise, Alberta, Canada
    Erik R Swenson
    Pulmonary Section 111 B, Department of Medicine, University of Washington, Veterans Administration Medical Center, 1660 S Columbian Way, Seattle, WA 98108 1597, USA
    High Alt Med Biol 6:181-8. 2005
  9. ncbi request reprint Pathogenesis of high-altitude pulmonary edema: inflammation is not an etiologic factor
    Erik R Swenson
    Pulmonary and Critical Care Section, S 111 Pulm, Veterans Affairs Puget Sound Health Care System, 1660 S Columbian Way, Seattle, WA 98108, USA
    JAMA 287:2228-35. 2002
    ....
  10. ncbi request reprint Inhibition of aquaporin-mediated CO2 diffusion and voltage-gated H+ channels by zinc does not alter rabbit lung CO2 and NO excretion
    Erik R Swenson
    Department of Medicine, VA Puget Sound Health Care System, University of Washington, Seattle, WA 98108, USA
    Clin Sci (Lond) 103:567-75. 2002
    ..Therefore we conclude that red cell and lung AQs and voltage-gated H(+) channels in the alveolar epithelium contribute minimally to normal physiological CO(2) elimination...
  11. ncbi request reprint Carbonic anhydrase inhibitors and hypoxic pulmonary vasoconstriction
    Erik R Swenson
    Department of Medicine, University of Washington, Seattle, WA 98195, USA
    Respir Physiol Neurobiol 151:209-16. 2006
    ....
  12. ncbi request reprint A comparative approach to carbonic anhydrase: the work of Thomas H. Maren
    Erik R Swenson
    Pulmonary and Critical Care Medicine, S 111 Pulm, VA Puget Sound Health Care System, Department of Medicine, University of Washington, 1660 South Columbian Way, Seattle, WA 98108, USA
    Comp Biochem Physiol A Mol Integr Physiol 136:229-41. 2003
    ..Using marine fish whose kidneys have very little CA, he uncovered mechanisms of acid-base transfer independent of CA that help to explain why CA inhibition does not lead to total bicarbonate depletion...
  13. ncbi request reprint Hemodilution during venous gas embolization improves gas exchange, without altering V(A)/Q or pulmonary blood flow distributions
    S Deem
    Department of Anesthesiology, Harborview Medical Center, University of Washington, Seattle 98104 2499, USA
    Anesthesiology 91:1861-72. 1999
    ..In the current study, the authors characterized the effects of hemodilution on gas exchange in a distinct model of diffuse lung injury: venous gas embolization...
  14. pmc Effects of carbonic anhydrase inhibition on ventilation-perfusion matching in the dog lung
    E R Swenson
    Department of Medicine, University of Washington, Seattle 98195
    J Clin Invest 92:702-9. 1993
    ..These results support the concept that lung CA subserves VA/Q matching in the normal lung...
  15. ncbi request reprint Acetazolamide reduces hypoxic pulmonary vasoconstriction in isolated perfused rabbit lungs
    S Deem
    Department of Anesthesiology, The University of Washington and Puget Sound Veterans Affairs Health Care System, Seattle, WA, USA
    Respir Physiol 123:109-19. 2000
    ..Acetazolamide did not affect expired nitric oxide concentrations. We conclude that acetazolamide reduces both the magnitude and kinetics of HPV by a mechanism that does not involve nitric oxide...
  16. ncbi request reprint In vivo quantitation of carbonic anhydrase and band 3 protein contributions to pulmonary gas exchange
    E R Swenson
    Department of Medicine, University of Washington, Seattle 98195
    J Appl Physiol (1985) 74:838-48. 1993
    ....
  17. ncbi request reprint Effects of the RBC membrane and increased perfusate viscosity on hypoxic pulmonary vasoconstriction
    S Deem
    Departments of Anesthesiology and Medicine, University of Washington, Washington 98195, USA
    J Appl Physiol (1985) 88:1520-8. 2000
    ..In conclusion, the RBC membrane provides a barrier to NO scavenging and augmentation of HPV by Hb. Increased perfusate viscosity inhibits HPV by an undetermined mechanism...
  18. ncbi request reprint Hypocapnia-induced ventilation/perfusion mismatch: a direct CO2 or pH-mediated effect?
    K B Domino
    Department of Anesthesiology, University of Washington School of Medicine, Seattle, USA
    Am J Respir Crit Care Med 152:1534-9. 1995
    ..Therefore, we conclude that hypocapnia-induced VA/Q mismatch in hyperventilated dogs is pH-mediated and is not a function of PCO2 per se...
  19. ncbi request reprint Renal carbonic anhydrase inhibition reduces high altitude sleep periodic breathing
    E R Swenson
    Department of Medicine, University of Washington, Seattle 98195
    Respir Physiol 86:333-43. 1991
    ..We conclude that metabolic acidosis occurring with all CA inhibitors is one of the major stimulant actions of these drugs on ventilation while awake and during sleep at high altitude...
  20. ncbi request reprint Hemoglobin and red blood cells alter the response of expired nitric oxide to mechanical forces
    J T Berg
    Departments of Medicine and Anesthesiology, Veterans Affairs Puget Sound Health Care System and the University of Washington, Seattle, Washington 98108, USA
    Am J Physiol Heart Circ Physiol 279:H2947-53. 2000
    ..We conclude that blood and systemic responses render it difficult to use NO(e) changes as an accurate measure of lung tissue NO production...
  21. ncbi request reprint Mechanisms of improvement in pulmonary gas exchange during isovolemic hemodilution
    S Deem
    Department of Anesthesiology, University of Washington, Seattle, Washington 98195, USA
    J Appl Physiol (1985) 87:132-41. 1999
    ..In turn, this may be a result of favorable changes in pulmonary blood flow distribution, as assessed by the fractal dimension and spatial correlation of blood flow and as a result of increased NO availability...
  22. ncbi request reprint Effects of S-nitrosation of hemoglobin on hypoxic pulmonary vasoconstriction and nitric oxide flux
    S Deem
    Departments of Anesthesiology and Medicine Pulmonary and Critical Care, University of Washington and Puget Sound Veterans Affairs Health Care System, Seattle, Washington, USA
    Am J Respir Crit Care Med 163:1164-70. 2001
    ..NO released from SNO-Hb in the presence of GSH does not produce measurable vascular effects in the lung or changes in eNO because of immediate oxidation and metHb formation...
  23. ncbi request reprint Travel to high altitude with pre-existing lung disease
    A M Luks
    Division of Pulmonary and Critical Care Medicine, University of Washington, Seattle, WA 98108, USA
    Eur Respir J 29:770-92. 2007
    ....
  24. ncbi request reprint Ventilation heterogeneity is increased in hypocapnic dogs but not pigs
    K B Domino
    Department of Anesthesiology, University of Washington, Seattle 98195 6540, USA
    Respir Physiol 111:89-100. 1998
    ..05) in pigs. We conclude that hypocapnia increases ventilation heterogeneity in dogs but not in pigs, most likely related to an interspecies difference in collateral ventilation...
  25. ncbi request reprint Red-blood-cell augmentation of hypoxic pulmonary vasoconstriction: hematocrit dependence and the importance of nitric oxide
    S Deem
    Department of Anesthesiology, Puget Sound Veterans Affairs Health System and the University of Washington, Seattle 98195 6540, USA
    Am J Respir Crit Care Med 157:1181-6. 1998
    ..Adenosine-receptor blockade did not affect the RBC-dependence of HPV. We conclude that HPV is dependent on Hct, and that this phenomenon may be related to scavenging of NO but not adenosine by RBCs...
  26. ncbi request reprint Identification and characterization of human neutrophil carbonic anhydrase
    A R Campbell
    Department of Veterans Affairs Medical Center, University of Washington, Seattle
    J Leukoc Biol 55:343-8. 1994
    ....
  27. ncbi request reprint The lung and carbon dioxide: implications for permissive and therapeutic hypercapnia
    D A Kregenow
    Division of Pulmonary and Critical Care Medicine University of Washington, Seattle, USA
    Eur Respir J 20:6-11. 2002
  28. ncbi request reprint Hypercapnic acidosis and mortality in acute lung injury
    David A Kregenow
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Washington, Seattle, WA, USA
    Crit Care Med 34:1-7. 2006
    ..We tested the hypothesis that hypercapnic acidosis is associated with reduced mortality rate in patients with acute lung injury independent of changes in mechanical ventilation...
  29. ncbi request reprint Carbonic anhydrases and mucosal vanilloid receptors help mediate the hyperemic response to luminal CO2 in rat duodenum
    Yasutada Akiba
    Department of Medicine, School of Medicine, University of California Los Angeles, USA
    Gastroenterology 131:142-52. 2006
    ..We examined the hyperemic response to elevated luminal PCO(2) in the duodenum of anesthetized rats luminally exposed to high CO(2) saline to help elucidate luminal acid-sensing mechanisms...
  30. ncbi request reprint Therapeutic hypercapnia and ventilation-perfusion matching in acute lung injury: low minute ventilation vs inspired CO2
    Scott E Sinclair
    Department of Medicine, University of Tennessee, 956 Court Ave, Room H314, Memphis, TN 38163, USA
    Chest 130:85-92. 2006
    ..We hypothesized the presence of hypercapnic acidosis from inspired carbon dioxide (ICD) would improve gas exchange in ALI and would be superior to that of low minute ventilation (LVe) produced by reduced respiratory rate, rather than Vt...
  31. ncbi request reprint Pulmonary vasodilation by acetazolamide during hypoxia is unrelated to carbonic anhydrase inhibition
    Claudia Höhne
    Klinik fur Anaesthesiologie und operative Intensivmedizin, Charite Universitatsmedizin Berlin, Campus Virchow Klinikum und Campus Mitte, Augustenburger Platz 1, D 13353 Berlin, Germany
    Am J Physiol Lung Cell Mol Physiol 292:L178-84. 2007
    ....
  32. ncbi request reprint Acetazolamide 125 mg BD is not significantly different from 375 mg BD in the prevention of acute mountain sickness: the prophylactic acetazolamide dosage comparison for efficacy (PACE) trial
    Buddha Basnyat
    Himalayan Rescue Association and Nepal International Clinic, Kathmandu, Nepal
    High Alt Med Biol 7:17-27. 2006
    ..02). We conclude that 125 mg bd of acetazolamide is not significantly different from 375 mg bd in the prevention of AMS; 125 mg bd should be considered the preferred dosage when indicated for persons ascending to altitudes above 2500 m...
  33. ncbi request reprint Red blood cells prevent inhibition of hypoxic pulmonary vasoconstriction by nitrite in isolated, perfused rat lungs
    Steven Deem
    Department of Anesthesiology, University of Washington, Seattle, WA, USA
    Am J Physiol Heart Circ Physiol 292:H963-70. 2007
    ....
  34. ncbi request reprint Prevention of acute mountain sickness by acetazolamide: as yet an unfinished story
    Erik R Swenson
    J Appl Physiol 102:1305-7. 2007
  35. ncbi request reprint Inhibition of hypoxia-induced calcium responses in pulmonary arterial smooth muscle by acetazolamide is independent of carbonic anhydrase inhibition
    Larissa A Shimoda
    Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, MD 21224, USA
    Am J Physiol Lung Cell Mol Physiol 292:L1002-12. 2007
    ..These results suggest that AZ attenuates HPV by selectively inhibiting hypoxia-induced Ca2+ responses via a mechanism independent of CA inhibition, changes in pH(i), or membrane potential...
  36. ncbi request reprint An ultracyclist with pulmonary edema during the Bicycle Race Across America
    Andrew M Luks
    Division of Pulmonary and Critical Care Medicine, University of Washington, Seattle, WA 98108, USA
    Med Sci Sports Exerc 39:8-12. 2007
    ....
  37. ncbi request reprint CO2 relaxes parenchyma in the liquid-filled rat lung
    Michael J Emery
    Department of Physiology, University of Washington School of Medicine, USA
    J Appl Physiol (1985) 103:710-6. 2007
    ....
  38. ncbi request reprint Leukotriene receptor blockade does not prevent acute mountain sickness induced by normobaric hypoxia
    Andrew M Luks
    Pulmonary and Critical Care Division, Department of Medicine, University of Washington, Seattle, Washington 98195 6522, USA
    High Alt Med Biol 8:131-8. 2007
    ..A 4-day course of leukotriene receptor blockade does not prevent symptoms of AMS. These results suggest that leukotrienes do not play a causal role in the pathophysiology of AMS...
  39. ncbi request reprint A patient with vanishing lung syndrome and remarkable tolerance to high altitude
    Andrew Mark Luks
    Division of Pulmonary and Critical Care Medicine, University of Washington, Seattle, WA 98195 6522, USA
    Med Sci Sports Exerc 39:1891-5. 2007
    ..Such travel may, in fact, be safe as long as the patient has undergone appropriate pretravel evaluation, and we provide recommendations regarding such evaluation in patients with chronic obstructive pulmonary disease...
  40. doi request reprint Medication and dosage considerations in the prophylaxis and treatment of high-altitude illness
    Andrew M Luks
    Division of Pulmonary and Critical Care Medicine, University of Washington, Seattle, WA 98195 6522, USA
    Chest 133:744-55. 2008
    ..By giving these issues adequate consideration, clinicians can increase the chances that properly evaluated patients with underlying medical conditions will enjoy a safe trip to high altitude...
  41. ncbi request reprint Physiological aspects of high-altitude pulmonary edema
    Peter Bartsch
    Department of Internal Medicine VII, Division of Sports Medicine, Medical University Hospital Heidelberg, Im Neuenheimer Feld 410, D 69120 Heidelberg, Germany
    J Appl Physiol (1985) 98:1101-10. 2005
    ..The combination of high flow at higher pressure results in pressures, which exceed the structural and dynamic capacity of the alveolar capillary barrier to maintain normal alveolar fluid balance...
  42. ncbi request reprint Hypoxic ventilatory response, ventilation, gas exchange, and fluid balance in acute mountain sickness
    Peter Bartsch
    Department of Internal Medicine, Division of Sports Medicine, Medical University Clinic, Heidelberg, Germany
    High Alt Med Biol 3:361-76. 2002
    ....
  43. ncbi request reprint Contributions of nitric oxide synthase isozymes to exhaled nitric oxide and hypoxic pulmonary vasoconstriction in rabbit lungs
    David J Vaughan
    Department of Pediatrics, Children s Hospital and Regional Medical Center, Seattle 98105, USA
    Am J Physiol Lung Cell Mol Physiol 284:L834-43. 2003
    ..Our findings show virtually all exhaled NO in the rabbit lung is produced by eNOS, which is present throughout the airways, alveoli, and vessels. Both vascular and epithelial-derived NO modulate HPV...
  44. ncbi request reprint Salmeterol for the prevention of high-altitude pulmonary edema
    Erik R Swenson
    N Engl J Med 347:1282-5; author reply 1282-5. 2002
  45. ncbi request reprint Effects of S-nitrosation and cross-linking of hemoglobin on hypoxic pulmonary vasoconstriction in isolated rat lungs
    Steven Deem
    Department of Anesthesiology, University of Washington and the Veterans Affairs Puget Sound Health Care Center, Seattle, Wash, USA
    Circ Res 91:626-32. 2002
    ..However, release of NO from SNO-Hb was not influenced by deoxygenation-mediated allosteric changes in Hb across a broad range of oxyHb saturation. Cross-linking of Hb does not limit its pulmonary vasoconstrictor effects...
  46. ncbi request reprint High altitude pulmonary oedema
    Peter Bartsch
    Department of Internal Medicine, Medical University Clinic Heidelberg, Germany
    Swiss Med Wkly 133:377-84. 2003
    ..Even susceptible individuals can avoid HAPE if they ascend slowly with an average gain of altitude not exceeding 300-350 m/day above an altitude of 2500 m...
  47. ncbi request reprint Altered ion transporter expression in bronchial epithelium in mountaineers with high-altitude pulmonary edema
    Heimo Mairbäurl
    Division of Sports Medicine, Department of Medicine, University of Heidelberg, Germany
    J Appl Physiol (1985) 95:1843-50. 2003
    ..It is therefore unclear whether these differences are related to the pathophysiology of HAPE...
  48. ncbi request reprint Carbon dioxide added late in inspiration reduces ventilation-perfusion heterogeneity without causing respiratory acidosis
    Thomas V Brogan
    Department of Pediatrics, Children s Hospital and Regional Medical Center, 4800 Sand Point Way NE, CH 05, Seattle, WA 98105 0371, USA
    J Appl Physiol (1985) 96:1894-8. 2004
    ..21). In conclusion, we have established that the majority of the improvement in gas exchange efficiency with inspired CO2 can be achieved by limiting its application to the conducting airways and does not require systemic acidosis...
  49. ncbi request reprint Nasal epithelium potential difference at high altitude (4,559 m): evidence for secretion
    Heimo Mairbäurl
    Division of Sports Medicine, Department of Medicine, University of Heidelberg, Luisenstrasse 5, Geb 4100, 69115 Heidelberg, Germany
    Am J Respir Crit Care Med 167:862-7. 2003
    ..It is therefore uncertain whether similar changes also occur at the alveolar epithelium...
  50. ncbi request reprint Inhibitors of hypoxic pulmonary vasoconstriction prevent high-altitude pulmonary edema in rats
    John T Berg
    Department of Pharmacology, University of Hawaii, Honolulu, HI 96822, USA
    Wilderness Environ Med 15:32-7. 2004
    ..This study was designed to assess whether preventing HPV reduces the alveolar-capillary barrier leak characteristic of HAPE...
  51. ncbi request reprint A dose-response study of acetazolamide for acute mountain sickness prophylaxis in vacationing tourists at 12,000 feet (3630 m)
    Chris Carlsten
    Department of Medicine, Medicine Residency Program, University of Washington School of Medicine, Seattle, WA 98122, USA
    High Alt Med Biol 5:33-9. 2004
    ..These results suggest that the dosing of acetazolamide for AMS prevention in nonmountaineering tourists at altitudes below 3700 m should not be lowered below 250 mg twice daily...
  52. ncbi request reprint Increased oxidative stress following acute and chronic high altitude exposure
    J Ashley Jefferson
    University of Washington, Division of Nephrology, Seattle, WA 98195, USA
    High Alt Med Biol 5:61-9. 2004
    ..In conclusion, oxidative stress is increased following both acute exposure to high altitude without exercise and with chronic residence at high altitude...
  53. ncbi request reprint Hyperuricemia, hypertension, and proteinuria associated with high-altitude polycythemia
    J Ashley Jefferson
    Department of Medicine and Laboratory Medicine, University of Washington Medical Center, Seattle, WA, USA
    Am J Kidney Dis 39:1135-42. 2002
    ..The increase in uric acid levels appears to be caused by increased urate generation secondary to systemic hypoxia, although a relative impairment in renal excretion also may contribute...
  54. ncbi request reprint Hemorrhage during isoflurane-nitrous oxide anesthesia: effects of endothelin-A or angiotensin II receptor blockade or both
    Claudia Höhne
    Clinic of Anesthesiology and Intensive Care Medicine, Campus Virchow Klinikum, Charite, Humboldt University of Berlin, Germany
    Anesthesiology 100:885-93. 2004
    ....
  55. ncbi request reprint Acetazolamide prevents hypoxic pulmonary vasoconstriction in conscious dogs
    Claudia Höhne
    Experimentelle Anaesthesie, Department of Anesthesiology and Intensive Care Medicine, Charite Universitatsmedizin Berlin, Campus Virchow Klinikum, Augustenburger Platz 1, D 13353 Berlin, Germany
    J Appl Physiol (1985) 97:515-21. 2004
    ..The effect is not due to Acz-induced hyperventilation and higher alveolar Po(2), nor to changes in plasma endothelin-1, angiotensin-II, or potassium, and HPV suppression occurs despite the systemic acidosis with CA inhibition...
  56. ncbi request reprint Excessive erythrocytosis, chronic mountain sickness, and serum cobalt levels
    J Ashley Jefferson
    Division of Nephrology, University of Washington Medical Center, Seattle, WA, USA
    Lancet 359:407-8. 2002
    ..In the mining community of Cerro de Pasco, cobalt toxicity might be an important contributor to excessive erythrocytosis...
  57. ncbi request reprint Pulmonary vascular effects of red blood cells containing S-nitrosated hemoglobin
    Steven Deem
    Dept of Anesthesiology, PO Box 359724, Harborview Medical Center, Seattle, WA 98104 2499, USA
    Am J Physiol Heart Circ Physiol 287:H2561-8. 2004
    ....
  58. ncbi request reprint Therapeutic hypercapnia: are we in "stasis" or moving forward?
    David A Kregenow
    Crit Care Med 36:2473-4. 2008
  59. ncbi request reprint Pulmonary extravascular fluid accumulation in climbers
    Peter Bartsch
    Lancet 360:571; author reply 571-2. 2002
  60. ncbi request reprint Membrane inlet for mass spectrometric measurement of nitric oxide
    Chingkuang Tu
    Department of Pharmacology and Therapeutics, College of Medicine, University of Florida, Gainesville, FL 32610, USA
    Free Radic Biol Med 43:1453-7. 2007
    ..0 nM. This apparatus was used to measure the generation of NO from solutions of nitrite, NONOates, and nitroprusside. The usefulness of such an inlet in measuring NO in physiological systems is discussed...
  61. ncbi request reprint High-altitude pulmonary edema getting worse after descent? An unlikely event
    Andrew M Luks
    Wilderness Environ Med 18:71-2; author reply 72. 2007
  62. ncbi request reprint Comet tails in high-altitude pulmonary edema: diagnostic portent or streak in the sky?
    Andrew M Luks
    Chest 131:951-3. 2007
  63. ncbi request reprint What do dead-space measurements tell us about the lung with acute respiratory distress syndrome?
    H Thomas Robertson
    Respir Care 49:1006-7. 2004
  64. ncbi request reprint Therapeutic hypercapnic acidosis: pushing the envelope
    Erik R Swenson
    Am J Respir Crit Care Med 169:8-9. 2004
  65. ncbi request reprint ACE inhibitors and high altitude
    Erik R Swenson
    High Alt Med Biol 5:92-4. 2004
  66. ncbi request reprint Carbonic anhydrase in mammalian vascular smooth muscle
    John T Berg
    Department of Pharmacology, University of Hawaii, Honolulu, HI, USA
    J Histochem Cytochem 52:1101-6. 2004
    ..These data establish the activity, inhibition, and isozyme pattern of carbonic anhydrase expression in mammalian vascular smooth muscle...
  67. ncbi request reprint Hypoxic lung whiteout: further clearing but more questions from on high
    Erik R Swenson
    Ann Intern Med 145:550-2. 2006