Sarah M Sweitzer

Summary

Affiliation: University of South Carolina
Country: USA

Publications

  1. doi request reprint Neonatal morphine enhances nociception and decreases analgesia in young rats
    Guo Hua Zhang
    Department of Pharmacology, Physiology and Neuroscience, University of South Carolina School of Medicine, Columbia, SC 29208, USA
    Brain Res 1199:82-90. 2008
  2. ncbi request reprint What is the future of diabetic wound care?
    Sarah M Sweitzer
    Department of Pharmacology, Physiology, and Neuroscience, University of South Carolina, School of Medicine, Columbia, 29208, USA
    Diabetes Educ 32:197-210. 2006
  3. ncbi request reprint Exaggerated nociceptive responses on morphine withdrawal: roles of protein kinase C epsilon and gamma
    Sarah M Sweitzer
    Department of Anesthesia, Stanford University School of Medicine, Stanford, CA 94305, USA
    Pain 110:281-9. 2004
  4. ncbi request reprint Mechanical allodynia and thermal hyperalgesia upon acute opioid withdrawal in the neonatal rat
    Sarah M Sweitzer
    Department of Anesthesia, Stanford University School of Medicine, Stanford, CA 94305, USA
    Pain 110:269-80. 2004
  5. ncbi request reprint Antinociceptive action of a p38alpha MAPK inhibitor, SD-282, in a diabetic neuropathy model
    Sarah M Sweitzer
    Department of Anesthesia, Stanford University School of Medicine, Stanford, CA 94305 5117, USA
    Pain 109:409-19. 2004
  6. ncbi request reprint Peripheral and central p38 MAPK mediates capsaicin-induced hyperalgesia
    S M Sweitzer
    Department of Anesthesia, Stanford University School of Medicine, Stanford, CA 94305, USA
    Pain 111:278-85. 2004
  7. ncbi request reprint Propentofylline attenuates vincristine-induced peripheral neuropathy in the rat
    S M Sweitzer
    Department of Pharmacology and Toxicology, Dartmouth Medical School, HB 7650, Hanover, NH 03755, USA
    Neurosci Lett 400:258-61. 2006
  8. ncbi request reprint Ethanol withdrawal-associated allodynia and hyperalgesia: age-dependent regulation by protein kinase C epsilon and gamma isoenzymes
    Jennifer A Shumilla
    Department of Anesthesiology, Stanford University School of Medicine, Stanford, CA, USA
    J Pain 6:535-49. 2005
  9. ncbi request reprint Acute and chronic ethanol exacerbates formalin pain in neonatal rats
    Jennifer A Shumilla
    Department of Anesthesiology, Stanford University School of Medicine, Stanford, CA 94305, USA
    Neurosci Lett 367:29-33. 2004
  10. pmc Endothelin-1 exposure on postnatal day 7 alters expression of the endothelin B receptor and behavioral sensitivity to endothelin-1 on postnatal day 11
    Alvin D McKelvy
    Department of Pharmacology, Physiology and Neuroscience, University of South Carolina School of Medicine, 6439 Garner s Ferry Road, Columbia, SC 29208, USA
    Neurosci Lett 451:89-93. 2009

Detail Information

Publications31

  1. doi request reprint Neonatal morphine enhances nociception and decreases analgesia in young rats
    Guo Hua Zhang
    Department of Pharmacology, Physiology and Neuroscience, University of South Carolina School of Medicine, Columbia, SC 29208, USA
    Brain Res 1199:82-90. 2008
    ..The present study illustrates the need to examine the long-term influence of prenatal morphine exposure on pain and analgesia in the human pediatric population...
  2. ncbi request reprint What is the future of diabetic wound care?
    Sarah M Sweitzer
    Department of Pharmacology, Physiology, and Neuroscience, University of South Carolina, School of Medicine, Columbia, 29208, USA
    Diabetes Educ 32:197-210. 2006
    ..With the recognition that the research approach will require both time and money, the best treatment approach is the prevention of diabetic ulcers through better foot care, education, and glycemic control...
  3. ncbi request reprint Exaggerated nociceptive responses on morphine withdrawal: roles of protein kinase C epsilon and gamma
    Sarah M Sweitzer
    Department of Anesthesia, Stanford University School of Medicine, Stanford, CA 94305, USA
    Pain 110:281-9. 2004
    ....
  4. ncbi request reprint Mechanical allodynia and thermal hyperalgesia upon acute opioid withdrawal in the neonatal rat
    Sarah M Sweitzer
    Department of Anesthesia, Stanford University School of Medicine, Stanford, CA 94305, USA
    Pain 110:269-80. 2004
    ..The present work illustrates the need to examine the phenomenon of hypersensitivity upon opioid withdrawal in the human pediatric population...
  5. ncbi request reprint Antinociceptive action of a p38alpha MAPK inhibitor, SD-282, in a diabetic neuropathy model
    Sarah M Sweitzer
    Department of Anesthesia, Stanford University School of Medicine, Stanford, CA 94305 5117, USA
    Pain 109:409-19. 2004
    ..These results indicate a potential therapeutic value of p38alpha MAPK inhibitors in the treatment of aberrant pain sensitivity produced by diabetes...
  6. ncbi request reprint Peripheral and central p38 MAPK mediates capsaicin-induced hyperalgesia
    S M Sweitzer
    Department of Anesthesia, Stanford University School of Medicine, Stanford, CA 94305, USA
    Pain 111:278-85. 2004
    ..These results suggest that p38 MAPK plays a role in the development of hyperalgesic states, exerting effects both centrally in the spinal cord and peripherally in sensory C fibers...
  7. ncbi request reprint Propentofylline attenuates vincristine-induced peripheral neuropathy in the rat
    S M Sweitzer
    Department of Pharmacology and Toxicology, Dartmouth Medical School, HB 7650, Hanover, NH 03755, USA
    Neurosci Lett 400:258-61. 2006
    ..These data suggest that central glial cells may play an important role in the development of painful neuropathy following vincristine administration...
  8. ncbi request reprint Ethanol withdrawal-associated allodynia and hyperalgesia: age-dependent regulation by protein kinase C epsilon and gamma isoenzymes
    Jennifer A Shumilla
    Department of Anesthesiology, Stanford University School of Medicine, Stanford, CA, USA
    J Pain 6:535-49. 2005
    ..These studies demonstrate developmental differences in neonatal nociceptive responses after withdrawal from acute EtOH and implicate a role for specific PKC isozymes in EtOH withdrawal-associated allodynia and hyperalgesia...
  9. ncbi request reprint Acute and chronic ethanol exacerbates formalin pain in neonatal rats
    Jennifer A Shumilla
    Department of Anesthesiology, Stanford University School of Medicine, Stanford, CA 94305, USA
    Neurosci Lett 367:29-33. 2004
    ..Formalin responses were unchanged in P25 rats exposed to acute or chronic EtOH. The affects of EtOH on somatosensory processing are dependent upon the age at which exposure occurs...
  10. pmc Endothelin-1 exposure on postnatal day 7 alters expression of the endothelin B receptor and behavioral sensitivity to endothelin-1 on postnatal day 11
    Alvin D McKelvy
    Department of Pharmacology, Physiology and Neuroscience, University of South Carolina School of Medicine, 6439 Garner s Ferry Road, Columbia, SC 29208, USA
    Neurosci Lett 451:89-93. 2009
    ..These findings suggest that ET-1 exposure in the neonatal period sex-specifically alters expression of the ET(B) receptor and behavioral sensitivity to ET-1 whereby males show sensitization and females show de-sensitization...
  11. ncbi request reprint Hyperresponsiveness on washout of volatile anesthetics from isolated spinal cord compared to withdrawal from ethanol
    Shirley M E Wong
    Department of Anesthesia, Stanford University School of Medicine, Stanford, CA 94305 5117, USA
    Anesth Analg 100:413-36. 2005
    ....
  12. pmc Sensitization to acute procedural pain in pediatric sickle cell disease: modulation by painful vaso-occlusive episodes, age, and endothelin-1
    Alyssa M Schlenz
    Department of Psychology, University of South Carolina, Columbia, South Carolina 29208, USA
    J Pain 13:656-65. 2012
    ..Associations between the endothelin variables and pain prior to venipuncture were also observed...
  13. ncbi request reprint Acute and chronic morphine alters formalin pain in neonatal rats
    Maurice H Zissen
    Department of Anesthesiology, Stanford University School of Medicine, Stanford, CA 94305, USA
    Neurosci Lett 400:154-7. 2006
    ..These findings suggest that neonatal morphine exposure may have unintended consequences on inflammatory pain...
  14. ncbi request reprint Age- and sex-specific nociceptive response to endothelin-1
    Alvin D McKelvy
    Department of Pharmacology, Physiology, and Neuroscience, University of South Carolina School of Medicine, Columbia, SC 29208, USA
    J Pain 8:657-66. 2007
    ..This developmental approach to studying ET-1-induced pain further illustrates the need for understanding pain mechanisms as a function of the development of the organism so as to better treat pain across the life span...
  15. ncbi request reprint Protein kinase C epsilon and gamma: involvement in formalin-induced nociception in neonatal rats
    Sarah M Sweitzer
    Department of Anesthesia, Stanford University School of Medicine, Stanford, California, USA
    J Pharmacol Exp Ther 309:616-25. 2004
    ..Identifying the molecular mechanisms responsible for age-specific patterns of nociception is necessary for the rational development of novel therapeutic strategies for treating pediatric pain...
  16. pmc Decreased opioid analgesia in weanling rats exposed to endothelin-1 during infancy
    Alvin D McKelvy
    Department of Pharmacology, Physiology and Neuroscience, University of South Carolina School of Medicine, 6439 Garner s Ferry Road, Columbia, SC 29208, USA
    Neurosci Lett 466:144-8. 2009
    ..These findings suggest a sex-difference in the window of vulnerability and the mechanism by which an acute nociceptive event can induce morphine tolerance...
  17. pmc Protein kinase C in pain: involvement of multiple isoforms
    Kandy T Velazquez
    Department of Pharmacology, Physiology and Neuroscience, University of South Carolina School of Medicine, Columbia, SC 29208, USA
    Pharmacol Res 55:578-89. 2007
    ....
  18. pmc Tolerance develops to the antiallodynic effects of the peripherally acting opioid loperamide hydrochloride in nerve-injured rats
    Shao Qiu He
    Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins University, School of Medicine, Baltimore, MD, USA
    Pain 154:2477-86. 2013
    ..Our findings indicate that animals with neuropathic pain may develop acute tolerance to the antiallodynic effects of peripherally acting opioids after repetitive systemic and local drug administration...
  19. ncbi request reprint Acute and chronic ethanol does not affect incisional pain in neonatal rats
    Jennifer A Shumilla
    Department of Anesthesiology, Stanford University School of Medicine, Stanford, CA 94305, USA
    Neurosci Lett 366:332-5. 2004
    ..The extent and duration of mechanical allodynia and thermal hyperalgesia following incision was measured and found to be unaffected by prior EtOH exposure...
  20. ncbi request reprint GABAB receptors on central terminals of C-afferents mediate intersegmental Adelta-afferent evoked hypoalgesia
    Toni L Jones
    Anesthesia Department, Stanford University School of Medicine, CA 94305, USA
    Eur J Pain 9:233-42. 2005
    ..These findings indicate an intersegmental, sciatic Adelta-afferent-evoked hypoalgesic effect on saphenous C-afferent responses that is mediated by pre-synaptic GABA(B) receptors on the terminals of those C-afferents...
  21. pmc Information-seeking coping behaviors during painful procedures in African-American children with sickle cell disease
    Alyssa M Schlenz
    Department of Psychology, University of South Carolina, Columbia, SC, USA
    Pain Manag Nurs 14:e54-8. 2013
    ..This pattern of coping is discussed within the context of cultural factors that may be important in understanding responses to procedural pain in pediatric sickle cell disease. ..
  22. doi request reprint Enhanced peripheral analgesia using virally mediated gene transfer of the mu-opioid receptor in mice
    Guohua Zhang
    Department of Pharmacology, Physiology and Neuroscience, University of South Carolina School of Medicine, Columbia, South Carolina 29208, USA
    Anesthesiology 108:305-13. 2008
    ..The current study used a recombinant herpes simplex virus type 1 to increase expression of the mu-opioid receptor (muOR) in primary afferent neurons. The goal of this strategy was to enhance peripheral opioid analgesia...
  23. ncbi request reprint Inhibition of spinal protein kinase C-epsilon or -gamma isozymes does not affect halothane minimum alveolar anesthetic concentration in rats
    Jennifer A Shumilla
    Department of Anesthesia, Stanford University School of Medicine, Stanford, California 94305, USA
    Anesth Analg 99:82-4. 2004
    ....
  24. pmc Criterion and convergent validity for 4 measures of pain in a pediatric sickle cell disease population
    Catherine B McClellan
    Department of Psychology, School of Medicine, University of South Carolina, Columbia, SC 29208, USA
    Clin J Pain 25:146-52. 2009
    ..To evaluate the psychometric properties of 4 measures of acute pain in youth with sickle cell disease (SCD) during a medical procedure...
  25. pmc Tolerance, opioid-induced allodynia and withdrawal associated allodynia in infant and young rats
    M H Zissen
    Department of Anesthesia, Stanford University School of Medicine, Stanford, CA 94305, USA
    Neuroscience 144:247-62. 2007
    ..Furthermore, tolerance, opioid-induced hypersensitivity, and withdrawal-associated hypersensitivity are age-specific and may be mediated by distinct mechanisms...
  26. ncbi request reprint Propentofylline, a glial modulating agent, exhibits antiallodynic properties in a rat model of neuropathic pain
    S M Sweitzer
    Department of Pharmacology and Toxicology, Dartmouth College, Hanover, New Hampshire, USA
    J Pharmacol Exp Ther 297:1210-7. 2001
    ....
  27. ncbi request reprint Acute peripheral inflammation induces moderate glial activation and spinal IL-1beta expression that correlates with pain behavior in the rat
    S M Sweitzer
    Department of Pharmacology, Dartmouth Medical School, Hanover, NH 03755, USA
    Brain Res 829:209-21. 1999
    ..These findings support a unifying theory that glial activation and cytokine expression have a similar, if not related, role in producing hyperalgesia following either peripheral inflammation or peripheral nerve injury...
  28. ncbi request reprint Ameroid rings for gradual chronic constriction of the sciatic nerve in rats: contribution of different nerves to neuropathic pain
    A Tzabazis
    Department of Anesthesia, Stanford University School of Medicine, 300 Pasteur Drive, S 276 Stanford, CA 94305, USA
    Brain Res Bull 64:127-32. 2004
    ..The uninjured saphenous afferents, in particular C fibers, mediate thermal hyperalgesia after chronic constriction of the sciatic nerve using an ameroid ring...
  29. ncbi request reprint Afferent fiber-selective shift in opiate potency following targeted opioid receptor knockdown
    Toni L Jones
    Department of Anesthesia, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305 5117, USA
    Pain 106:365-71. 2003
    ....
  30. ncbi request reprint Focal peripheral nerve injury induces leukocyte trafficking into the central nervous system: potential relationship to neuropathic pain
    Sarah M Sweitzer
    Department of Pharmacology, Dartmouth Medical School, Hanover, NH 03756, USA
    Pain 100:163-70. 2002
    ..This study demonstrates trafficking of leukocytes into the lumbar spinal cord at time points that correlate with mechanical allodynia suggesting a role of central neuroinflammation in persistent neuropathic pain...
  31. ncbi request reprint Differential opioid inhibition of C- and A delta- fiber mediated thermonociception after stimulation of the nucleus raphe magnus
    Ying Lu
    Department of Anesthesiology, University of Illinois at Chicago, Chicago, Illinois, USA
    Anesth Analg 98:414-9, table of contents. 2004
    ..These findings suggest that nociception evoked by the activation of A delta or C fiber nociceptors is under pharmacologically distinguishable descending control from the nucleus raphe magnus...