J David Sweatt

Summary

Affiliation: University of Alabama at Birmingham
Country: USA

Publications

  1. pmc Interindividual Variability in Stress Susceptibility: A Role for Epigenetic Mechanisms in PTSD
    Iva B Zovkic
    Department of Neurobiology, Evelyn F McKnight Brain Institute, University of Alabama at Birmingham, Birmingham, AL, USA
    Front Psychiatry 4:60. 2013
  2. pmc The emerging field of neuroepigenetics
    J David Sweatt
    Department of Neurobiology and Evelyn F McKnight Brain Institute, University of Alabama at Birmingham, Birmingham, AL 35294, USA Electronic address
    Neuron 80:624-32. 2013
  3. pmc Pitt-Hopkins Syndrome: intellectual disability due to loss of TCF4-regulated gene transcription
    J David Sweatt
    Department of Neurobiology and Evelyn F McKnight Brain Institute, Civitan International Research Center, University of Alabama at Birmingham, Birmingham, AL 35294 2182, USA
    Exp Mol Med 45:e21. 2013
  4. doi request reprint Histone H2A.Z subunit exchange controls consolidation of recent and remote memory
    Iva B Zovkic
    Department of Neurobiology and Evelyn F McKnight Brain Institute, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    Nature 515:582-6. 2014
  5. pmc Transcriptional and epigenetic regulation of Hebbian and non-Hebbian plasticity
    Mikael C Guzman-Karlsson
    Department of Neurobiology, University of Alabama at Birmingham, Birmingham, AL, USA
    Neuropharmacology 80:3-17. 2014
  6. doi request reprint DNA methylation and its implications and accessibility for neuropsychiatric therapeutics
    Jeremy J Day
    Department of Neurobiology, University of Alabama at Birmingham, Birmingham, Alabama 35294 email
    Annu Rev Pharmacol Toxicol 55:591-611. 2015
  7. pmc TET1 controls CNS 5-methylcytosine hydroxylation, active DNA demethylation, gene transcription, and memory formation
    GARRETT A KAAS
    Department of Neurobiology and Evelyn F McKnight Brain Institute, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Neuron 79:1086-93. 2013
  8. doi request reprint The role of the Gadd45 family in the nervous system: a focus on neurodevelopment, neuronal injury, and cognitive neuroepigenetics
    Faraz A Sultan
    Department of Neurobiology, University of Alabama at Birmingham, Shelby 1010, 1825 University Blvd, Birmingham, AL, 35294, USA
    Adv Exp Med Biol 793:81-119. 2013
  9. pmc DNA methylation regulates associative reward learning
    Jeremy J Day
    1 Department of Neurobiology, University of Alabama at Birmingham, Birmingham, Alabama, USA 2 Evelyn F McKnight Brain Institute, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Nat Neurosci 16:1445-52. 2013

Collaborators

  • John J Hablitz
  • Guo li Ming
  • Hongjun Song
  • Jeremy J Day
  • Iva B Zovkic
  • Mikael C Guzman-Karlsson
  • GARRETT A KAAS
  • Jarrod P Meadows
  • Faraz A Sultan
  • Andrew J Kennedy
  • Cristin F Gavin
  • Deepa M Etikala
  • Brynna S Paulukaitis
  • Absar Tahir
  • Jennifer R King
  • Jerome Moulden
  • Esther Song
  • Daniel L Ross
  • Chun Zhong
  • Mercy Kibe
  • Raj V Vachhani
  • Daniel Childs
  • Dawn E Eason

Detail Information

Publications9

  1. pmc Interindividual Variability in Stress Susceptibility: A Role for Epigenetic Mechanisms in PTSD
    Iva B Zovkic
    Department of Neurobiology, Evelyn F McKnight Brain Institute, University of Alabama at Birmingham, Birmingham, AL, USA
    Front Psychiatry 4:60. 2013
    ....
  2. pmc The emerging field of neuroepigenetics
    J David Sweatt
    Department of Neurobiology and Evelyn F McKnight Brain Institute, University of Alabama at Birmingham, Birmingham, AL 35294, USA Electronic address
    Neuron 80:624-32. 2013
    ..In this brief commentary, I will attempt to address and delineate some of the open questions and areas of opportunity that discoveries in epigenetics are providing to the discipline of neuroscience. ..
  3. pmc Pitt-Hopkins Syndrome: intellectual disability due to loss of TCF4-regulated gene transcription
    J David Sweatt
    Department of Neurobiology and Evelyn F McKnight Brain Institute, Civitan International Research Center, University of Alabama at Birmingham, Birmingham, AL 35294 2182, USA
    Exp Mol Med 45:e21. 2013
    ....
  4. doi request reprint Histone H2A.Z subunit exchange controls consolidation of recent and remote memory
    Iva B Zovkic
    Department of Neurobiology and Evelyn F McKnight Brain Institute, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    Nature 515:582-6. 2014
    ..Overall, our data introduce histone variant exchange as a novel mechanism contributing to the molecular basis of cognitive function and implicate H2A.Z as a potential therapeutic target for memory disorders. ..
  5. pmc Transcriptional and epigenetic regulation of Hebbian and non-Hebbian plasticity
    Mikael C Guzman-Karlsson
    Department of Neurobiology, University of Alabama at Birmingham, Birmingham, AL, USA
    Neuropharmacology 80:3-17. 2014
    ..In doing so, we aim to expand upon the idea that epigenetic mechanisms are critical regulators of both Hebbian and non-Hebbian forms of plasticity that ultimately drive learning and memory...
  6. doi request reprint DNA methylation and its implications and accessibility for neuropsychiatric therapeutics
    Jeremy J Day
    Department of Neurobiology, University of Alabama at Birmingham, Birmingham, Alabama 35294 email
    Annu Rev Pharmacol Toxicol 55:591-611. 2015
    ..Lastly, we speculate upon potential categories of CNS cognitive disorders that might be amenable to methylomic targeting. ..
  7. pmc TET1 controls CNS 5-methylcytosine hydroxylation, active DNA demethylation, gene transcription, and memory formation
    GARRETT A KAAS
    Department of Neurobiology and Evelyn F McKnight Brain Institute, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Neuron 79:1086-93. 2013
    ..In summary, we show that neuronal Tet1 regulates DNA methylation levels and that its expression, independent of its catalytic activity, regulates the expression of CNS activity-dependent genes and memory formation...
  8. doi request reprint The role of the Gadd45 family in the nervous system: a focus on neurodevelopment, neuronal injury, and cognitive neuroepigenetics
    Faraz A Sultan
    Department of Neurobiology, University of Alabama at Birmingham, Shelby 1010, 1825 University Blvd, Birmingham, AL, 35294, USA
    Adv Exp Med Biol 793:81-119. 2013
    ..In this review, we provide a comprehensive discussion of the literature implicating each of the three members of the Gadd45 family in these processes. ..
  9. pmc DNA methylation regulates associative reward learning
    Jeremy J Day
    1 Department of Neurobiology, University of Alabama at Birmingham, Birmingham, Alabama, USA 2 Evelyn F McKnight Brain Institute, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Nat Neurosci 16:1445-52. 2013
    ..These results provide the first evidence that that activity-dependent methylation and demethylation of DNA is an essential substrate for the behavioral and neuronal plasticity driven by reward-related experiences. ..