Kim Sutton-Tyrrell

Summary

Affiliation: University of Pittsburgh
Country: USA

Publications

  1. pmc Effects of weight loss and insulin reduction on arterial stiffness in the SAVE trial
    Timothy M Hughes
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA
    Cardiovasc Diabetol 11:114. 2012
  2. ncbi request reprint Extent of cardiovascular risk reduction associated with treatment of isolated systolic hypertension
    Kim Sutton-Tyrrell
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA
    Arch Intern Med 163:2728-31. 2003
  3. ncbi request reprint Elevated aortic pulse wave velocity, a marker of arterial stiffness, predicts cardiovascular events in well-functioning older adults
    Kim Sutton-Tyrrell
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, PA 15261, USA
    Circulation 111:3384-90. 2005
  4. pmc Reproductive hormones and obesity: 9 years of observation from the Study of Women's Health Across the Nation
    Kim Sutton-Tyrrell
    Department of Epidemiology, University of Pittsburgh, Pennsylvania 15261, USA
    Am J Epidemiol 171:1203-13. 2010
  5. doi request reprint Relationship of ankle blood pressures to cardiovascular events in older adults
    Kim Sutton-Tyrrell
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, GSPH 505A Parran Hall, 130 DeSoto Street, Pittsburgh, PA 15261, USA
    Stroke 39:863-9. 2008
  6. ncbi request reprint Sex-hormone-binding globulin and the free androgen index are related to cardiovascular risk factors in multiethnic premenopausal and perimenopausal women enrolled in the Study of Women Across the Nation (SWAN)
    Kim Sutton-Tyrrell
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, 127 Parran Hall 130 DeSoto St, Pittsburgh, PA 15261, USA
    Circulation 111:1242-9. 2005
  7. ncbi request reprint Is cardiovascular reactivity associated with atherosclerosis among hypertensives?
    Peter J Gianaros
    Cardiovascular Behavioral Medicine Research Program, University of Pittsburgh, Pennsylvania, USA
    Hypertension 40:742-7. 2002
  8. pmc Aortic stiffness and calcification in men in a population-based international study
    Akira Sekikawa
    Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Atherosclerosis 222:473-7. 2012
  9. pmc Intima-media thickness of the carotid artery and the distribution of lipoprotein subclasses in men aged 40 to 49 years between whites in the United States and the Japanese in Japan for the ERA JUMP study
    Akira Sekikawa
    Department of Epidemiology, Graduate School of Pubic Health, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Metabolism 57:177-82. 2008
  10. pmc Ethnic difference in liver fat content: a cross-sectional observation among Japanese American in Hawaii, Japanese in Japan, and non-Hispanic whites in United States
    Koichiro Azuma
    Division of Endocrinology and Metabolism, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA
    Obes Res Clin Pract 7:e198-205. 2013

Detail Information

Publications74

  1. pmc Effects of weight loss and insulin reduction on arterial stiffness in the SAVE trial
    Timothy M Hughes
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA
    Cardiovasc Diabetol 11:114. 2012
    ..The purpose of this study was to determine how insulin levels modify the improvements in arterial stiffness seen with weight loss in overweight and obese young adults...
  2. ncbi request reprint Extent of cardiovascular risk reduction associated with treatment of isolated systolic hypertension
    Kim Sutton-Tyrrell
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA
    Arch Intern Med 163:2728-31. 2003
    ..However, nearly 20% of older adults remain at high risk of heart disease and stroke from untreated ISH...
  3. ncbi request reprint Elevated aortic pulse wave velocity, a marker of arterial stiffness, predicts cardiovascular events in well-functioning older adults
    Kim Sutton-Tyrrell
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, PA 15261, USA
    Circulation 111:3384-90. 2005
    ..The objective of this investigation was to determine whether aPWV is associated with total and cardiovascular (CV) mortality and CV events in a community-dwelling sample of older adults...
  4. pmc Reproductive hormones and obesity: 9 years of observation from the Study of Women's Health Across the Nation
    Kim Sutton-Tyrrell
    Department of Epidemiology, University of Pittsburgh, Pennsylvania 15261, USA
    Am J Epidemiol 171:1203-13. 2010
    ....
  5. doi request reprint Relationship of ankle blood pressures to cardiovascular events in older adults
    Kim Sutton-Tyrrell
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, GSPH 505A Parran Hall, 130 DeSoto Street, Pittsburgh, PA 15261, USA
    Stroke 39:863-9. 2008
    ..We focus on the extent to which low and high ankle-arm index values as well as noncompressible arteries are associated with mortality and cardiovascular events, including stroke in older adults...
  6. ncbi request reprint Sex-hormone-binding globulin and the free androgen index are related to cardiovascular risk factors in multiethnic premenopausal and perimenopausal women enrolled in the Study of Women Across the Nation (SWAN)
    Kim Sutton-Tyrrell
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, 127 Parran Hall 130 DeSoto St, Pittsburgh, PA 15261, USA
    Circulation 111:1242-9. 2005
    ..Recent clinical trials have shifted attention away from estrogens and toward androgens and sex hormone-binding globulin (SHBG) as potential mediators of increasing cardiovascular (CV) risk in women at midlife...
  7. ncbi request reprint Is cardiovascular reactivity associated with atherosclerosis among hypertensives?
    Peter J Gianaros
    Cardiovascular Behavioral Medicine Research Program, University of Pittsburgh, Pennsylvania, USA
    Hypertension 40:742-7. 2002
    ..Among hypertensives, exaggerated behaviorally evoked cardiovascular reactivity appears to be uniquely associated with greater carotid intima-media thickness but not with carotid plaque occurrence...
  8. pmc Aortic stiffness and calcification in men in a population-based international study
    Akira Sekikawa
    Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Atherosclerosis 222:473-7. 2012
    ..The goal of this study was to examine the association of aortic calcification and stiffness in multi-ethnic population-based samples of relatively young men...
  9. pmc Intima-media thickness of the carotid artery and the distribution of lipoprotein subclasses in men aged 40 to 49 years between whites in the United States and the Japanese in Japan for the ERA JUMP study
    Akira Sekikawa
    Department of Epidemiology, Graduate School of Pubic Health, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Metabolism 57:177-82. 2008
    ..671 +/- 0.006 mm for the whites and 0.618 +/- 0.006 mm for the Japanese, P = .01, mean +/- SE). Differences in the distributions of NMR lipoproteins between the 2 populations did not explain the higher IMT in the whites...
  10. pmc Ethnic difference in liver fat content: a cross-sectional observation among Japanese American in Hawaii, Japanese in Japan, and non-Hispanic whites in United States
    Koichiro Azuma
    Division of Endocrinology and Metabolism, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA
    Obes Res Clin Pract 7:e198-205. 2013
    ..Objective: We hypothesize that ethnic difference in fat storage capacity contributes to this ethnic difference in liver fat...
  11. pmc Less subclinical atherosclerosis in Japanese men in Japan than in White men in the United States in the post-World War II birth cohort
    Akira Sekikawa
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, 130 North Bellefield Avenue, Pittsburgh, PA 15213, USA
    Am J Epidemiol 165:617-24. 2007
    ..616 mm (standard error, 0.005) vs. 0.672 (standard error, 0.005) mm, p < 0.01). Both associations remained significant after adjusting for risk factors. The findings warrant further investigations...
  12. pmc Are changes in cardiovascular disease risk factors in midlife women due to chronological aging or to the menopausal transition?
    Karen A Matthews
    Department of Psychiatry and Psychology, University of Pittsburgh, Pittsburgh, PA 15213, USA
    J Am Coll Cardiol 54:2366-73. 2009
    ....
  13. pmc Are vasomotor symptoms associated with alterations in hemostatic and inflammatory markers? Findings from the Study of Women's Health Across the Nation
    Rebecca C Thurston
    Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Menopause 18:1044-51. 2011
    ..We aimed to examine the longitudinal associations between hot flashes/night sweats and both inflammatory and hemostatic markers, controlling for cardiovascular risk factors and estradiol concentrations...
  14. pmc Association of serum n-6 and n-3 polyunsaturated fatty acids with lipids in 3 populations of middle-aged men
    Kenneth R Motoyama
    Department of Epidemiology, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA 15261, USA
    Am J Clin Nutr 90:49-55. 2009
    ..The association of serum polyunsaturated fatty acids (PUFAs) with lipids in different populations is not known...
  15. pmc Vasomotor symptoms and insulin resistance in the study of women's health across the nation
    Rebecca C Thurston
    Department of Psychiatry, University of Pittsburgh School of Medicine, 3811 O Hara Street, Pittsburgh, Pennsylvania 15213, USA
    J Clin Endocrinol Metab 97:3487-94. 2012
    ..OBJECTIVE AND MAIN OUTCOME MEASURES: We examined the associations between hot flashes/night sweats and glucose and insulin resistance over 8 yr, controlling for cardiovascular risk factors and reproductive hormones...
  16. doi request reprint Progression of carotid intima-media thickness and plaque in women with systemic lupus erythematosus
    Trina Thompson
    University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
    Arthritis Rheum 58:835-42. 2008
    ....
  17. ncbi request reprint Hemostatic factors and estrogen during the menopausal transition
    MaryFran R Sowers
    Department of Epidemiology, University of Michigan School of Public Health, 339 East Liberty Street, Suite 310, Ann Arbor, Michigan 48104, USA
    J Clin Endocrinol Metab 90:5942-8. 2005
    ..Therefore, we evaluated endogenous hormone concentrations, menopause transition stages, and adoption of exogenous hormone use in relation to hemostatic and inflammation marker concentrations in women...
  18. pmc Recurrent major depression predicts progression of coronary calcification in healthy women: Study of Women's Health Across the Nation
    Karen A Matthews
    Department of Psychiatry, University of Pittsburgh, 3811 O Hara Street, Pittsburgh, PA 15213, USA
    Psychosom Med 72:742-7. 2010
    ..It is less clear whether depression is related to the progression of atherosclerosis before the onset of CHD events...
  19. ncbi request reprint Elevated pulse wave velocity increases the odds of coronary calcification in overweight postmenopausal women
    Lakshmi Venkitachalam
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Am J Hypertens 20:469-75. 2007
    ..Our aim is to evaluate the association between both these measures of arterial stiffness and coronary calcification (CAC), in overweight/obese postmenopausal women, without apparent cardiovascular disease...
  20. pmc Is brachial artery flow-mediated dilation associated with negative affect?
    Laura L Schott
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, 130 DeSoto Street, A546 Crabtree Hall, Pittsburgh, PA 15261, USA
    Int J Behav Med 16:241-7. 2009
    ..Trait negative affect has been implicated as a risk marker for cardiovascular disease, but the mechanisms underlying this association are uncertain...
  21. ncbi request reprint Relation of cardiovascular risk factors in women approaching menopause to menstrual cycle characteristics and reproductive hormones in the follicular and luteal phases
    Karen A Matthews
    Department of Psychiatry, University of Pittsburgh, Pennsylvania 15213, USA
    J Clin Endocrinol Metab 91:1789-95. 2006
    ..Menstrual cycle characteristics may be associated with cardiovascular disease (CVD) risk...
  22. ncbi request reprint Subclinical atherosclerosis in multiple vascular beds: an index of atherosclerotic burden evaluated in postmenopausal women
    Kim Sutton-Tyrrell
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, 130 DeSoto Street, Pittsburgh, PA 15261, USA
    Atherosclerosis 160:407-16. 2002
    ..Women with lower premenopausal risk factors did not develop high levels of subclinical atherosclerosis, suggesting that atherosclerosis is a preventable disease in women...
  23. ncbi request reprint Hormone therapy, lipoprotein subclasses, and coronary calcification: the Healthy Women Study
    Rachel H Mackey
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, 130 DeSoto Street, Pittsburgh, PA 15261, USA
    Arch Intern Med 165:510-5. 2005
    ..To test this hypothesis, we evaluated differences in coronary calcification, lipids, and lipoprotein subclasses among HT users and nonusers in a longitudinal study of the menopause...
  24. ncbi request reprint Relationship between coronary artery calcification and other measures of subclinical cardiovascular disease in older adults
    Anne B Newman
    Division of Geriatric Medicine, University of Pittsburgh, PA 15213, USA
    Arterioscler Thromb Vasc Biol 22:1674-9. 2002
    ..In the Cardiovascular Health Study, subclinical cardiovascular disease (CVD) predicted CVD events in older adults. The extent to which this measure or its components reflect calcified coronary disease is unknown...
  25. pmc Adiponectin, systolic blood pressure, and alcohol consumption are associated with more aortic stiffness progression among apparently healthy men
    Samar R El Khoudary
    University of Pittsburgh, Pittsburgh, PA 15261, USA
    Atherosclerosis 225:475-80. 2012
    ..We examined several risk factors as possible independent predictors of aortic stiffness progression among a population-based sample of US men...
  26. pmc The prevalence of aortic calcification in Japanese compared to white and Japanese-American middle-aged men is confounded by the amount of cigarette smoking
    Aiman El-Saed
    Graduate School of Public Health, University of Pittsburgh, Pittsburgh, USA
    Int J Cardiol 167:134-9. 2013
    ..It is unclear if aortic calcification (AC) strongly linked to smoking is also lower in Japanese men who have many times higher smoking prevalence compared to US men...
  27. pmc Differential association of docosahexaenoic and eicosapentaenoic acids with carotid intima-media thickness
    Akira Sekikawa
    Assistant Professor of Epidemiology, Graduate School of Public Health, University of Pittsburgh, 130 North Bellefield Avenue, Suite 546, Pittsburgh, PA 15213, USA
    Stroke 42:2538-43. 2011
    ..S. white individuals and explored whether DHA or EPA contributes to the difference in IMT between the two groups...
  28. pmc African-American ethnicity and cardiovascular risk factors are related to aortic pulse-wave velocity progression
    Mehret S Birru
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Am J Hypertens 24:809-15. 2011
    ..Little is known about the relationships between CVD risk factors and PWV progression among women transitioning through the menopause, or whether these relationships vary by ethnicity...
  29. ncbi request reprint Lipoprotein subclasses and coronary artery calcium in postmenopausal women from the healthy women study
    Rachel H Mackey
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA
    Am J Cardiol 90:71i-76i. 2002
    ..These results suggest that the measurement of lipoprotein subclasses may improve the prediction of CAD in postmenopausal women beyond that provided by the conventional lipid panel and CAD risk factors...
  30. pmc Do carotid artery diameters manifest early evidence of atherosclerosis in women with rheumatoid arthritis?
    Laura L Schott
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA
    J Womens Health (Larchmt) 18:21-9. 2009
    ..We take a unique approach by evaluating lumen and interadventitial diameters in addition to intima-media thickness and plaque...
  31. pmc Changes in serum aldosterone are associated with changes in obesity-related factors in normotensive overweight and obese young adults
    Jennifer N Cooper
    1 Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA 2 Department of Biostatistics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA
    Hypertens Res 36:895-901. 2013
    ....
  32. pmc Much lower prevalence of coronary calcium detected by electron-beam computed tomography among men aged 40-49 in Japan than in the US, despite a less favorable profile of major risk factors
    Akira Sekikawa
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, 3512 Fifth Avenue, Pittsburgh, PA 15213, USA
    Int J Epidemiol 34:173-9. 2005
    ..We compared the degree of coronary calcium and other factors in men in the post WWII birth cohort: men aged 40-49 in the US and Japan...
  33. ncbi request reprint Segment-specific effects of cardiovascular risk factors on carotid artery intima-medial thickness in women at midlife
    Laura L Schott
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, 127 Parran Hall, 130 DeSoto Street, Pittsburgh, PA 15261, USA
    Arterioscler Thromb Vasc Biol 24:1951-6. 2004
    ..We investigated associations between segment-specific carotid intima-medial thickness (IMT) and cardiovascular risk factors collected before menopause for insight into mechanisms of atherosclerosis development...
  34. pmc Vasomotor symptoms and lipid profiles in women transitioning through menopause
    Rebecca C Thurston
    Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Obstet Gynecol 119:753-61. 2012
    ..To examine associations between vasomotor symptoms and lipids over 8 years, controlling for other cardiovascular risk factors, estradiol, and follicle-stimulating hormone...
  35. pmc Circulating levels of 8 cytokines and marine n-3 fatty acids and indices of obesity in Japanese, white, and Japanese American middle-aged men
    Akira Sekikawa
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    J Interferon Cytokine Res 30:541-8. 2010
    ..Generally cytokines had weak and nonsignificant associations with indices of obesity and marine n-3 FA. Further investigation is needed to determine why JJ had lower circulating levels of cytokines...
  36. pmc C-reactive protein and coronary artery calcium in asymptomatic women with systemic lupus erythematosus or rheumatoid arthritis
    Amy H Kao
    Department of Medicine, Division of Rheumatology and Clinical Immunology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Am J Cardiol 102:755-60. 2008
    ..The increased odds for CAC may in part result from higher levels of inflammation and endothelial activation in these patients...
  37. pmc Do reports of sleep disturbance relate to coronary and aortic calcification in healthy middle-aged women?: Study of women's health across the nation
    Karen A Matthews
    University of Pittsburgh, Department of Psychiatry, Pittsburgh, PA 15213, USA
    Sleep Med 14:282-7. 2013
    ..We evaluated cross-sectional associations between self-reported sleep disturbance and duration and calcification in the coronary arteries (CAC) and aorta (AC) in healthy mid-life women...
  38. pmc The association of menopause status with physical function: the Study of Women's Health Across the Nation
    Lisa A Tseng
    Clinical Scientist Training Program, School of Medicine, Department of Epidemiology, School of Public Health, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Menopause 19:1186-92. 2012
    ..The aim of this study was to determine whether postmenopause status is associated with self-reported limitations in physical function...
  39. ncbi request reprint Experiences of demand and control in daily life as correlates of subclinical carotid atherosclerosis in a healthy older sample
    Thomas W Kamarck
    Department of Psychology, University of Pittsburgh, Pittsburgh, PA 15260, USA
    Health Psychol 23:24-32. 2004
    ..Previous findings linking job stress with cardiovascular disease may reflect the broader impact of daily psychological demands, not necessarily associated with the workplace...
  40. ncbi request reprint Cardiovascular risk factors associated with enlarged diameter of the abdominal aortic and iliac arteries in healthy women
    Ami S Patel
    Department of Epidemiology, University of Pittsburgh, 127 Parran Hall, 130 DeSoto Street, Pittsburgh, PA 15261, USA
    Atherosclerosis 178:311-7. 2005
    ..Women at mid-life should continue to be targeted for weight interventions to reduce their risk for more serious cardiovascular complications...
  41. pmc Coronary calcification is more predictive of carotid intimal medial thickness in black compared to white middle aged men
    Aiman El-Saed
    Department of Epidemiology, Graduate School of Public Health, Pittsburgh, USA
    Atherosclerosis 196:913-8. 2008
    ..Race-specific data for the association between coronary artery calcification (CAC) and carotid intimal medial thickness (IMT) are limited. We sought to compare black-white specific associations of these two measures...
  42. doi request reprint Long chain n-3 polyunsaturated fatty acids and incidence rate of coronary artery calcification in Japanese men in Japan and white men in the USA: population based prospective cohort study
    Akira Sekikawa
    Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Heart 100:569-73. 2014
    ....
  43. pmc Higher liver fat content among Japanese in Japan compared with non-Hispanic whites in the United States
    Koichiro Azuma
    Division of Endocrinology and Metabolism, Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Metabolism 58:1200-7. 2009
    ....
  44. pmc Racial differences in the association between carotid plaque and aortic and coronary artery calcification among women transitioning through menopause
    Genevieve A Woodard
    Graduate School of Public Health, Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA 15217, USA
    Menopause 19:157-63. 2012
    ..The purpose of this report was to evaluate racial differences in the relationship between carotid plaque and calcification in the aorta and coronary arteries among women transitioning through menopause...
  45. pmc Trajectory clustering of estradiol and follicle-stimulating hormone during the menopausal transition among women in the Study of Women's Health across the Nation (SWAN)
    Ping G Tepper
    Departments of Epidemiology, University of Pittsburgh, Graduate School of Public Health, Pittsburgh, Pennsylvania 15261, USA
    J Clin Endocrinol Metab 97:2872-80. 2012
    ..Variability in the pattern of change in estradiol (E2) and FSH levels over the menopause transition has not been well defined...
  46. pmc Reductions in arterial stiffness with weight loss in overweight and obese young adults: potential mechanisms
    Jennifer N Cooper
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Epidemiology Data Center, 130 DeSoto St, Pittsburgh, PA 15261, USA
    Atherosclerosis 223:485-90. 2012
    ..Arterial stiffness decreases with weight loss in overweight/obese young adults. We aimed to determine the mechanisms by which this occurs...
  47. ncbi request reprint Negative emotions and 3-year progression of subclinical atherosclerosis
    Jesse C Stewart
    Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Arch Gen Psychiatry 64:225-33. 2007
    ....
  48. pmc Progression rates of carotid intima-media thickness and adventitial diameter during the menopausal transition
    Samar R El Khoudary
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA15213, USA
    Menopause 20:8-14. 2013
    ..The aim of this study is to assess whether the levels and progression rates of carotid intima-media thickness (IMT) and adventitial diameter (AD) vary by menopausal stage...
  49. ncbi request reprint Anger-related personality traits and carotid artery atherosclerosis in untreated hypertensive men
    Maria E Bleil
    Behavioral Physiology Laboratory, Department of Psychology, University of Pittsburgh, 4015 O Hara St, Pittsburgh, PA 15260, USA
    Psychosom Med 66:633-9. 2004
    ..To determine whether anger-related personality traits are associated with carotid artery atherosclerosis in untreated hypertensive patients...
  50. pmc Aortic pulse wave velocity predicts focal white matter hyperintensities in a biracial cohort of older adults
    Caterina Rosano
    Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA, USA
    Hypertension 61:160-5. 2013
    ....
  51. pmc Greater intima-media thickness in the carotid bulb is associated with reduced baroreflex sensitivity
    Peter J Gianaros
    Cardiovascular Behavioral Medicine Research Program, University of Pittsburgh, Pennsylvania, USA
    Am J Hypertens 15:486-91. 2002
    ..These results suggest that subclinical atherosclerosis, specifically in a region with high baroreceptor density, is associated with a reduced sensitivity of the baroreflex...
  52. pmc C-reactive protein is associated with aortic stiffness in a cohort of African American and white women transitioning through menopause
    Genevieve A Woodard
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA
    Menopause 18:1291-7. 2011
    ..The association between CRP and arterial stiffness is well accepted; however, no study has determined whether there are differences in this association by menopause status and race, independent of age...
  53. pmc Abdominal adiposity and hot flashes among midlife women
    Rebecca C Thurston
    From the 1Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA 15217, USA
    Menopause 15:429-34. 2008
    ..The study objective was to examine associations between abdominal adiposity and hot flashes, including the role of reproductive hormones in these associations...
  54. pmc Associations of D-dimer and von Willebrand factor with atherosclerosis in Japanese and white men
    Ryoko W Azuma
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Acta Cardiol 65:449-56. 2010
    ..S.). We examined whether the differences in D-dimer and vWF levels are associated with differences in atherosclerosis between the two populations...
  55. pmc Marine-derived n-3 fatty acids and atherosclerosis in Japanese, Japanese-American, and white men: a cross-sectional study
    Akira Sekikawa
    University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    J Am Coll Cardiol 52:417-24. 2008
    ..We sought to examine whether marine-derived n-3 fatty acids are associated with less atherosclerosis in Japanese versus white populations in the U.S...
  56. pmc The clinical trial of Women On the Move through Activity and Nutrition (WOMAN) study
    Lewis H Kuller
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, PA 15213, United States
    Contemp Clin Trials 28:370-81. 2007
    ..Body composition is measured by dual-energy X-ray absorptiometry...
  57. pmc Endogenous sex hormones impact the progression of subclinical atherosclerosis in women during the menopausal transition
    Samar R El Khoudary
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, United States
    Atherosclerosis 225:180-6. 2012
    ....
  58. pmc Difference in carotid intima-media thickness between Korean and Japanese men
    Jina Choo
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA
    Ann Epidemiol 18:310-5. 2008
    ..We aimed to evaluate levels of carotid intima-media thickness (IMT) and coronary risk factors in Korean and Japanese men in the post-World War II birth cohort...
  59. ncbi request reprint Racial differences in coronary artery calcification in older adults
    Anne B Newman
    Division of Geriatric Medicine, University of Pittsburgh, Pittsburgh VA Healthcare System, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    Arterioscler Thromb Vasc Biol 22:424-30. 2002
    ..The lower CAC scores in blacks compared with whites observed in this study is consistent with either a lower prevalence of coronary artery disease or a lower extent of calcification of coronary artery disease...
  60. pmc Hot flashes and carotid intima media thickness among midlife women
    Rebecca C Thurston
    Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    Menopause 18:352-8. 2011
    ..We hypothesized that reported hot flashes would be associated with greater IMT cross-sectionally and with greater IMT progression over 2 years...
  61. pmc Association between depression and coronary artery calcification in women with systemic lupus erythematosus
    Carol M Greco
    Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Rheumatology (Oxford) 48:576-81. 2009
    ..To determine the associations between depression, cardiovascular risk factors and coronary artery calcification (CAC) in women with SLE and controls...
  62. ncbi request reprint Androgens are associated with hemostatic and inflammatory factors among women at the mid-life
    MaryFran R Sowers
    University of Michigan, Department of Epidemiology, School of Public Health, 339 East Liberty Street, Suite 310, Ann Arbor, Michigan 48104, USA
    J Clin Endocrinol Metab 90:6064-71. 2005
    ..The goal of this study was to relate annually measured endogenous androgens to hemostatic and inflammation markers in women longitudinally...
  63. pmc Effect modification of obesity on associations between endogenous steroid sex hormones and arterial calcification in women at midlife
    Samar R El Khoudary
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA
    Menopause 18:906-14. 2011
    ..The aim of this study was to examine whether obesity modifies the effects of endogenous steroid sex hormones on arterial calcification in women at midlife...
  64. ncbi request reprint Psychosocial stress and cardiovascular risk: what is the role of daily experience?
    Thomas W Kamarck
    University of Pittsburgh, PA 15260, USA
    J Pers 73:1749-74. 2005
    ....
  65. pmc Association between depression and vascular disease in systemic lupus erythematosus
    Carol M Greco
    Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA 15232, USA
    J Rheumatol 39:262-8. 2012
    ..Although depression may contribute to CVD risk in population-based studies, its influence on cardiovascular morbidity in SLE has not been evaluated. We evaluated the association between depression and vascular disease in SLE...
  66. pmc Lipids, menopause, and early atherosclerosis in Study of Women's Health Across the Nation Heart women
    Genevieve A Woodard
    University of Pittsburgh Graduate School of Public Health, Department of Epidemiology, Pittsburgh, PA 15217, USA
    Menopause 18:376-84. 2011
    ..Our objective was to evaluate whether the relationship of HDL cholesterol (HDL-C) to subclinical cardiovascular disease differed across the menopausal transition, which would provide insight for this increased risk...
  67. ncbi request reprint Effect of weight loss and nutritional intervention on arterial stiffness in type 2 diabetes
    Emma Barinas-Mitchell
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Diabetes Care 29:2218-22. 2006
    ..However, the effect of intentional weight loss on arterial stiffness is uncertain, and the purpose of the current study was to assess this effect...
  68. ncbi request reprint Volumetric BMD and vascular calcification in middle-aged women: the Study of Women's Health Across the Nation
    Ghada N Farhat
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, PA 15261, USA
    J Bone Miner Res 21:1839-46. 2006
    ..Lower vBMD was related to high AC, but not to CAC, independent of age and shared risk factors between osteoporosis and cardiovascular disease...
  69. ncbi request reprint Obesity is associated with larger arterial diameters in Caucasian and African-American young adults
    Rachel P Wildman
    Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, USA
    Diabetes Care 27:2997-9. 2004
  70. ncbi request reprint Weight change is associated with change in arterial stiffness among healthy young adults
    Rachel P Wildman
    Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, USA
    Hypertension 45:187-92. 2005
    ..These data greatly underscore the vascular benefit of weight loss. Successful weight loss programs in young adults, particularly blacks, are needed...
  71. ncbi request reprint Measures of obesity are associated with vascular stiffness in young and older adults
    Rachel P Wildman
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA
    Hypertension 42:468-73. 2003
    ..The strength of the association, the early age at which it appears, and the prevalence of obesity among the young warn of substantially increased cardiovascular disease incidence as this cohort ages...
  72. pmc Early signs of cardiovascular disease in youth with obesity and type 2 diabetes
    Neslihan Gungor
    Division of Endocrinology, Children s Hospital of Pittsburgh, 3705 Fifth Avenue at DeSoto Street, Pittsburgh, PA 15213, USA
    Diabetes Care 28:1219-21. 2005
  73. ncbi request reprint Subclinical atherosclerosis and estimated glucose disposal rate as predictors of mortality in type 1 diabetes
    Jon C Olson
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA
    Ann Epidemiol 12:331-7. 2002
    ....

Research Grants28

  1. PREVALENCE & PROGRESSION OF SUBCLINICAL ATHEROSCLEROSIS
    KIM TYRRELL; Fiscal Year: 2001
    ....
  2. VASCULAR STIFFNESS AND EFFECTS OF DIETARY INTERVENTION
    KIM TYRRELL; Fiscal Year: 2002
    ....
  3. PREVALENCE & PROGRESSION OF SUBCLINICAL ATHEROSCLEROSIS
    KIM TYRRELL; Fiscal Year: 2001
    ....
  4. PREVALENCE & PROGRESSION OF SUBCLINICAL ATHEROSCLEROSIS
    KIM TYRRELL; Fiscal Year: 2002
    ....
  5. PREVALENCE & PROGRESSION OF SUBCLINICAL ATHEROSCLEROSIS
    KIM TYRRELL; Fiscal Year: 2003
    ....
  6. Clinical Trail to Reverse Early Arterial Stiffening
    KIM TYRRELL; Fiscal Year: 2006
    ..A more thorough understanding of the mechanism linking obesity, sodium consumption and vascular health can be used to formulate targeted therapies for obesity-related vascular damage. ..
  7. Clinical Trail to Reverse Early Arterial Stiffening
    KIM TYRRELL; Fiscal Year: 2007
    ..A more thorough understanding of the mechanism linking obesity, sodium consumption and vascular health can be used to formulate targeted therapies for obesity-related vascular damage. ..
  8. Study/Women/Health Across Nation III/Coordinating Center
    KIM TYRRELL; Fiscal Year: 2007
    ..With SWAN III, many of the original goals of SWAN will be brought to fruition. We will build upon the rich foundation developed during SWAN I and II and link these data to important menopauserelated and health outcomes in SWAN III. ..
  9. Clinical Trail to Reverse Early Arterial Stiffening
    KIM TYRRELL; Fiscal Year: 2009
    ..A more thorough understanding of the mechanism linking obesity, sodium consumption and vascular health can be used to formulate targeted therapies for obesity-related vascular damage. ..
  10. EPIDEMIOLOGY OF CAROTID ARTERY DISEASE IN OLDER ADULTS
    KIM TYRRELL; Fiscal Year: 2001
    ..It is predicted that the results will be directly applicable to the largest growing segment of the U.S. population. ..
  11. VASCULAR STIFFNESS AND EFFECTS OF DIETARY INTERVENTION
    KIM TYRRELL; Fiscal Year: 2001
    ....
  12. VASCULAR STIFFNESS AND EFFECTS OF DIETARY INTERVENTION
    KIM TYRRELL; Fiscal Year: 1999
    ....
  13. EPIDEMIOLOGY OF CAROTID ARTERY DISEASE IN OLDER ADULTS
    KIM TYRRELL; Fiscal Year: 1993
    ..In summary, this proposal will provide a wealth of information on the relationship between carotid disease, systolic hypertension and morbidity and mortality not available from any other source...
  14. EPIDEMIOLOGY OF CAROTID ARTERY DISEASE IN OLDER ADULTS
    KIM TYRRELL; Fiscal Year: 1999
    ..It is predicted that the results will be directly applicable to the largest growing segment of the U.S. population. ..
  15. VASCULAR STIFFNESS AND EFFECTS OF DIETARY INTERVENTION
    KIM TYRRELL; Fiscal Year: 2000
    ....
  16. EPIDEMIOLOGY OF CAROTID ARTERY DISEASE IN OLDER ADULTS
    KIM TYRRELL; Fiscal Year: 2000
    ..It is predicted that the results will be directly applicable to the largest growing segment of the U.S. population. ..
  17. PREVALENCE & PROGRESSION OF SUBCLINICAL ATHEROSCLEROSIS
    KIM TYRRELL; Fiscal Year: 2000
    ....
  18. Clinical Trail to Reverse Early Arterial Stiffening
    Kim Sutton Tyrrell; Fiscal Year: 2010
    ..A more thorough understanding of the mechanism linking obesity, sodium consumption and vascular health can be used to formulate targeted therapies for obesity-related vascular damage. ..