Michael R Sussman

Summary

Affiliation: University of Wisconsin
Country: USA

Publications

  1. Gallant J, Traeger L, Volkening J, Moffett H, Chen P, Novina C, et al. Nonhuman genetics. Genomic basis for the convergent evolution of electric organs. Science. 2014;344:1522-5 pubmed publisher
  2. E Stecker K, Minkoff B, Sussman M. Phosphoproteomic Analyses Reveal Early Signaling Events in the Osmotic Stress Response. Plant Physiol. 2014;165:1171-1187 pubmed
    ..The results of these experiments demonstrate the utility of targeted phosphoproteomic analysis in understanding protein regulation networks and provide new insight into cellular processes involved in the osmotic stress response. ..
  3. Nguyen T, Sabat G, Sussman M. In vivo cross-linking supports a head-to-tail mechanism for regulation of the plant plasma membrane P-type H+-ATPase. J Biol Chem. 2018;293:17095-17106 pubmed publisher
  4. Volkening J, Stecker K, Sussman M. Proteome-wide Analysis of Protein Thermal Stability in the Model Higher Plant Arabidopsis thaliana. Mol Cell Proteomics. 2019;18:308-319 pubmed publisher
  5. Haruta M, Gray W, Sussman M. Regulation of the plasma membrane proton pump (H(+)-ATPase) by phosphorylation. Curr Opin Plant Biol. 2015;28:68-75 pubmed publisher
    ..Only by combining biochemical and genetic experiments can we attempt to meet these challenges to understand the essential molecular details by which this protein functions in planta. ..
  6. Traeger L, Volkening J, Moffett H, Gallant J, Chen P, Novina C, et al. Unique patterns of transcript and miRNA expression in the South American strong voltage electric eel (Electrophorus electricus). BMC Genomics. 2015;16:243 pubmed publisher
    ..Moreover, these data and future studies will be informed by the first comprehensive analysis of miRNA expression in an electric fish presented here. ..
  7. Haruta M, Sussman M. Ligand Receptor-Mediated Regulation of Growth in Plants. Curr Top Dev Biol. 2017;123:331-363 pubmed publisher
  8. Ivancic M, Irving A, Jonakin K, Dove W, Sussman M. The concentrations of EGFR, LRG1, ITIH4, and F5 in serum correlate with the number of colonic adenomas in ApcPirc/+ rats. Cancer Prev Res (Phila). 2014;7:1160-9 pubmed publisher
    ..The results of this study demonstrate that the quantitative analysis of a panel of serum proteins can detect the presence of early intestinal tumors in a rat model, and provides support for future measurements in humans. ..
  9. Nguyen T, Volkening J, Rose C, Venkateshwaran M, Westphall M, Coon J, et al. Potential regulatory phosphorylation sites in a Medicago truncatula plasma membrane proton pump implicated during early symbiotic signaling in roots. FEBS Lett. 2015;589:2186-93 pubmed publisher

More Information

Publications11

  1. Minkoff B, Makino S, Haruta M, Beebe E, Wrobel R, Fox B, et al. A cell-free method for expressing and reconstituting membrane proteins enables functional characterization of the plant receptor-like protein kinase FERONIA. J Biol Chem. 2017;292:5932-5942 pubmed publisher
    ..These data represent a step further toward understanding the molecular basis for the protein kinase catalytic activity of FERONIA and show promise for future characterization of eukaryotic membrane proteins. ..
  2. Minkoff B, Blatz J, Choudhury F, Benjamin D, Shohet J, Sussman M. Plasma-Generated OH Radical Production for Analyzing Three-Dimensional Structure in Protein Therapeutics. Sci Rep. 2017;7:12946 pubmed publisher
    ..These results demonstrate that plasma-generated hydroxyl radicals from water can be used to map protein conformational changes, and provide a readily accessible means of studying protein structure in solution. ..