Research Topics
| Robert W SummersSummaryAffiliation: University of Iowa Country: USA Publications
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Detail Information
Publications
Trichuris suis seems to be safe and possibly effective in the treatment of inflammatory bowel diseaseRobert W Summers
Department of Internal Medicine, James A. Clifton Center for Digestive Diseases, University of Iowa Health Care, Iowa City, Iowa, USA
Am J Gastroenterol 98:2034-41. 2003..The study suggests that it is possible to downregulate aberrant intestinal inflammation in humans with helminths...
Trichuris suis therapy in Crohn's diseaseR W Summers
James A Clifton Center for Digestive Diseases, Department of Internal Medicine, University of Iowa Roy J and Lucille A Carver College of Medicine, 200 Hawkins Drive, Iowa City, IA 52242, USA
Gut 54:87-90. 2005..Helminths diminish immune responsiveness in naturally colonised humans and reduce inflammation in experimental colitis. Thus exposure to helminths may help prevent or even ameliorate Crohn's disease...
Novel and future medical management of inflammatory bowel diseaseRobert W Summers
Division of Gastroenterology and Hepatology, Department of Internal Medicine, 4545 JCP, University of Iowa, Carver College of Medicine, 200 Hawkins Drive, Iowa City, IA 52242, USA
Surg Clin North Am 87:727-41. 2007..Still, control of ulcerative colitis and Crohn's is improving with more changes likely to come...
Is there a role for helminths in the therapy of inflammatory bowel disease?Robert W Summers
James A Clifton Center for Digestive Disease, Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City 52242, USA
Nat Clin Pract Gastroenterol Hepatol 2:62-3. 2005
Trichuris suis therapy for active ulcerative colitis: a randomized controlled trialRobert W Summers
James A Clifton Center for Digestive Diseases, Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, Iowa 52242, USA
Gastroenterology 128:825-32. 2005..In animal models, helminths prevent or improve colitis by the induction of regulatory T cells and modulatory cytokines. This study determined the efficacy and safety of the helminth Trichuris suis in therapy of ulcerative colitis...
Helminths as governors of immune-mediated inflammationDavid E Elliott
Department of Internal Medicine, University of Iowa, Roy J and Lucille A Carver College of Medicine, 200 Hawkins Drive, Iowa City, IA 52242 1009, USA
Int J Parasitol 37:457-64. 2007..This paper summarises work by multiple groups demonstrating that colonization with helminths alters immune reactivity and protects against disease from dysregulated inflammation...
The possible link between de-worming and the emergence of immunological diseaseJoel V Weinstock
Division of Gastroenterology-Hepatology, Department of Internal Medicine, University of Iowa, Iowa City, IA 52242, USA
J Lab Clin Med 139:334-8. 2002
Helminths and the modulation of mucosal inflammationDavid E Elliott
Division of Gastroenterology Hepatology, Department of Internal Medicine, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, Iowa 52242 1009, USA
Curr Opin Gastroenterol 21:51-8. 2005..This review summarizes some of the recent findings showing that helminths induce regulatory circuits that could prevent and treat inflammatory bowel disease...
Business plan to establish a CT colonography serviceLaurie L Fajardo
Department of Radiology, Carver College of Medicine, University of Iowa, Iowa City, Iowa 52242, USA
J Am Coll Radiol 3:175-86. 2006..Finally, the planning committee acknowledged and accommodated needs specific to the missions of an academic medical center with respect to research and education in designing the new service...
Role of helminths in regulating mucosal inflammationJoel V Weinstock
Department of Internal Medicine, Division of Gastroenterology Hepatology, University of Iowa, Iowa City, IA 52242 1009, USA
Springer Semin Immunopathol 27:249-71. 2005..These effects by once ubiquitous organisms may have protected individuals from many of the emerging immune-mediated illnesses like IBD, multiple sclerosis, type I diabetes, and asthma...
Therapeutic colonization with Trichuris suisRobert W Summers
Arch Pathol Lab Med 130:1753; author reply 1753-4. 2006
Why Trichuris suis should prove safe for use in inflammatory bowel diseasesRobert W Summers
Inflamm Bowel Dis 11:783-4. 2005
A randomized trial of aspirin to prevent colorectal adenomasJohn A Baron
Norris Cotton Cancer Center, Dartmouth Hitchcock Medical Center, Lebanon, NH, USA
N Engl J Med 348:891-9. 2003..Laboratory and epidemiologic data suggest that aspirin has an antineoplastic effect in the large bowel...
Folic acid for the prevention of colorectal adenomas: a randomized clinical trialBernard F Cole
Department of Community and Family Medicine, Dartmouth Medical School, Hanover, NH, USA
JAMA 297:2351-9. 2007..Laboratory and epidemiological data suggest that folic acid may have an antineoplastic effect in the large intestine...
