Robert W Summers

Summary

Affiliation: University of Iowa
Country: USA

Publications

  1. ncbi request reprint Trichuris suis seems to be safe and possibly effective in the treatment of inflammatory bowel disease
    Robert W Summers
    Department of Internal Medicine, James A Clifton Center for Digestive Diseases, University of Iowa Health Care, Iowa City, Iowa, USA
    Am J Gastroenterol 98:2034-41. 2003
  2. pmc Trichuris suis therapy in Crohn's disease
    R W Summers
    James A Clifton Center for Digestive Diseases, Department of Internal Medicine, University of Iowa Roy J and Lucille A Carver College of Medicine, 200 Hawkins Drive, Iowa City, IA 52242, USA
    Gut 54:87-90. 2005
  3. ncbi request reprint Novel and future medical management of inflammatory bowel disease
    Robert W Summers
    Division of Gastroenterology and Hepatology, Department of Internal Medicine, 4545 JCP, University of Iowa, Carver College of Medicine, 200 Hawkins Drive, Iowa City, IA 52242, USA
    Surg Clin North Am 87:727-41. 2007
  4. ncbi request reprint Is there a role for helminths in the therapy of inflammatory bowel disease?
    Robert W Summers
    James A Clifton Center for Digestive Disease, Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City 52242, USA
    Nat Clin Pract Gastroenterol Hepatol 2:62-3. 2005
  5. ncbi request reprint Trichuris suis therapy for active ulcerative colitis: a randomized controlled trial
    Robert W Summers
    James A Clifton Center for Digestive Diseases, Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, Iowa 52242, USA
    Gastroenterology 128:825-32. 2005
  6. ncbi request reprint Helminths as governors of immune-mediated inflammation
    David E Elliott
    Department of Internal Medicine, University of Iowa, Roy J and Lucille A Carver College of Medicine, 200 Hawkins Drive, Iowa City, IA 52242 1009, USA
    Int J Parasitol 37:457-64. 2007
  7. ncbi request reprint The possible link between de-worming and the emergence of immunological disease
    Joel V Weinstock
    Division of Gastroenterology Hepatology, Department of Internal Medicine, University of Iowa, Iowa City, IA 52242, USA
    J Lab Clin Med 139:334-8. 2002
  8. ncbi request reprint Helminths and the modulation of mucosal inflammation
    David E Elliott
    Division of Gastroenterology Hepatology, Department of Internal Medicine, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, Iowa 52242 1009, USA
    Curr Opin Gastroenterol 21:51-8. 2005
  9. ncbi request reprint Business plan to establish a CT colonography service
    Laurie L Fajardo
    Department of Radiology, Carver College of Medicine, University of Iowa, Iowa City, Iowa 52242, USA
    J Am Coll Radiol 3:175-86. 2006
  10. ncbi request reprint Role of helminths in regulating mucosal inflammation
    Joel V Weinstock
    Department of Internal Medicine, Division of Gastroenterology Hepatology, University of Iowa, Iowa City, IA 52242 1009, USA
    Springer Semin Immunopathol 27:249-71. 2005

Collaborators

  • Joel V Weinstock
  • David Elliott
  • Joseph F Urban
  • Laurie L Fajardo
  • JOHN ANTHONY BARON
  • Bernard F Cole
  • Timothy R Church
  • John I Allen
  • John H Bond
  • Judy R Rees
  • Norman Marcon
  • Richard I Rothstein
  • Per Magne Ueland
  • Leila A Mott
  • Carol A Burke
  • Robert S Bresalier
  • Fred Saibil
  • Elizabeth L Barry
  • E Robert Greenberg
  • Jack S Mandel
  • Loretta H Pearson
  • Tim Byers
  • Douglas J Robertson
  • Gail McKeown-Eyssen
  • Dale C Snover
  • Robert W Haile
  • Gerald J Beck
  • Robert S Sandler
  • Dennis J Ahnen

Detail Information

Publications14

  1. ncbi request reprint Trichuris suis seems to be safe and possibly effective in the treatment of inflammatory bowel disease
    Robert W Summers
    Department of Internal Medicine, James A Clifton Center for Digestive Diseases, University of Iowa Health Care, Iowa City, Iowa, USA
    Am J Gastroenterol 98:2034-41. 2003
    ..Induction of a Th2 immune response by intestinal helminths diminishes Th1 responsiveness. This study evaluates the safety and effectiveness of helminthic ova in the treatment of active IBD...
  2. pmc Trichuris suis therapy in Crohn's disease
    R W Summers
    James A Clifton Center for Digestive Diseases, Department of Internal Medicine, University of Iowa Roy J and Lucille A Carver College of Medicine, 200 Hawkins Drive, Iowa City, IA 52242, USA
    Gut 54:87-90. 2005
    ..Helminths diminish immune responsiveness in naturally colonised humans and reduce inflammation in experimental colitis. Thus exposure to helminths may help prevent or even ameliorate Crohn's disease...
  3. ncbi request reprint Novel and future medical management of inflammatory bowel disease
    Robert W Summers
    Division of Gastroenterology and Hepatology, Department of Internal Medicine, 4545 JCP, University of Iowa, Carver College of Medicine, 200 Hawkins Drive, Iowa City, IA 52242, USA
    Surg Clin North Am 87:727-41. 2007
    ..Still, control of ulcerative colitis and Crohn's is improving with more changes likely to come...
  4. ncbi request reprint Is there a role for helminths in the therapy of inflammatory bowel disease?
    Robert W Summers
    James A Clifton Center for Digestive Disease, Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City 52242, USA
    Nat Clin Pract Gastroenterol Hepatol 2:62-3. 2005
  5. ncbi request reprint Trichuris suis therapy for active ulcerative colitis: a randomized controlled trial
    Robert W Summers
    James A Clifton Center for Digestive Diseases, Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, Iowa 52242, USA
    Gastroenterology 128:825-32. 2005
    ..In animal models, helminths prevent or improve colitis by the induction of regulatory T cells and modulatory cytokines. This study determined the efficacy and safety of the helminth Trichuris suis in therapy of ulcerative colitis...
  6. ncbi request reprint Helminths as governors of immune-mediated inflammation
    David E Elliott
    Department of Internal Medicine, University of Iowa, Roy J and Lucille A Carver College of Medicine, 200 Hawkins Drive, Iowa City, IA 52242 1009, USA
    Int J Parasitol 37:457-64. 2007
    ..This paper summarises work by multiple groups demonstrating that colonization with helminths alters immune reactivity and protects against disease from dysregulated inflammation...
  7. ncbi request reprint The possible link between de-worming and the emergence of immunological disease
    Joel V Weinstock
    Division of Gastroenterology Hepatology, Department of Internal Medicine, University of Iowa, Iowa City, IA 52242, USA
    J Lab Clin Med 139:334-8. 2002
  8. ncbi request reprint Helminths and the modulation of mucosal inflammation
    David E Elliott
    Division of Gastroenterology Hepatology, Department of Internal Medicine, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, Iowa 52242 1009, USA
    Curr Opin Gastroenterol 21:51-8. 2005
    ..This review summarizes some of the recent findings showing that helminths induce regulatory circuits that could prevent and treat inflammatory bowel disease...
  9. ncbi request reprint Business plan to establish a CT colonography service
    Laurie L Fajardo
    Department of Radiology, Carver College of Medicine, University of Iowa, Iowa City, Iowa 52242, USA
    J Am Coll Radiol 3:175-86. 2006
    ..Finally, the planning committee acknowledged and accommodated needs specific to the missions of an academic medical center with respect to research and education in designing the new service...
  10. ncbi request reprint Role of helminths in regulating mucosal inflammation
    Joel V Weinstock
    Department of Internal Medicine, Division of Gastroenterology Hepatology, University of Iowa, Iowa City, IA 52242 1009, USA
    Springer Semin Immunopathol 27:249-71. 2005
    ..These effects by once ubiquitous organisms may have protected individuals from many of the emerging immune-mediated illnesses like IBD, multiple sclerosis, type I diabetes, and asthma...
  11. ncbi request reprint Therapeutic colonization with Trichuris suis
    Robert W Summers
    Arch Pathol Lab Med 130:1753; author reply 1753-4. 2006
  12. ncbi request reprint Why Trichuris suis should prove safe for use in inflammatory bowel diseases
    Robert W Summers
    Inflamm Bowel Dis 11:783-4. 2005
  13. ncbi request reprint A randomized trial of aspirin to prevent colorectal adenomas
    John A Baron
    Norris Cotton Cancer Center, Dartmouth Hitchcock Medical Center, Lebanon, NH, USA
    N Engl J Med 348:891-9. 2003
    ..Laboratory and epidemiologic data suggest that aspirin has an antineoplastic effect in the large bowel...
  14. ncbi request reprint Folic acid for the prevention of colorectal adenomas: a randomized clinical trial
    Bernard F Cole
    Department of Community and Family Medicine, Dartmouth Medical School, Hanover, NH, USA
    JAMA 297:2351-9. 2007
    ..Laboratory and epidemiological data suggest that folic acid may have an antineoplastic effect in the large intestine...