Jesse Summers

Summary

Affiliation: University of New Mexico
Country: USA

Publications

  1. ncbi Residual integrated viral DNA after hepadnavirus clearance by nucleoside analog therapy
    Jesse Summers
    Department of Molecular Genetics and Microbiology, University of New Mexico, Albuquerque, NM 87131, USA
    Proc Natl Acad Sci U S A 101:638-40. 2004
  2. ncbi Examining the theory of error catastrophe
    Jesse Summers
    Department of Molecular Genetics and Microbiology, University of New Mexico, Albuquerque, NM 87131, USA
    J Virol 80:20-6. 2006
  3. ncbi Rapid production of neutralizing antibody leads to transient hepadnavirus infection
    Yong-Yuan Zhang
    Department of Molecular Genetics and Microbiology, University of New Mexico School of Medicine, Albuquerque, New Mexico 87131, USA
    J Virol 78:1195-201. 2004
  4. ncbi Single-cell analysis of covalently closed circular DNA copy numbers in a hepadnavirus-infected liver
    Yong-Yuan Zhang
    Department of Molecular Genetics and Microbiology, University of New Mexico, 915 Camino de Salud Northeast, Albuquerque, NM 87131, USA
    Proc Natl Acad Sci U S A 100:12372-7. 2003
  5. ncbi Hepatocyte turnover during resolution of a transient hepadnaviral infection
    Jesse Summers
    Department of Molecular Genetics and Microbiology, University of New Mexico, Albuquerque, NM 87131, USA
    Proc Natl Acad Sci U S A 100:11652-9. 2003
  6. ncbi Genomic DNA double-strand breaks are targets for hepadnaviral DNA integration
    Colin A Bill
    Department of Molecular Genetics and Microbiology, University of New Mexico, 915 Camino de Salud NE, Albuquerque, NM 87131, USA
    Proc Natl Acad Sci U S A 101:11135-40. 2004
  7. ncbi Age-related differences in amplification of covalently closed circular DNA at early times after duck hepatitis B virus infection of ducks
    Yong Yuan Zhang
    Department of Molecular Genetics and Microbiology, University of New Mexico School of Medicine, Albuquerque, 87131, USA
    J Virol 79:9896-903. 2005
  8. ncbi Clonal expansion of hepatocytes during chronic woodchuck hepatitis virus infection
    William S Mason
    Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, PA 19111, USA
    Proc Natl Acad Sci U S A 102:1139-44. 2005

Research Grants

  1. GENERATION/EMERGENCE OF VARIANT IN HEPADNAVIRUS INFECTON
    Jesse Summers; Fiscal Year: 2004

Collaborators

Detail Information

Publications8

  1. ncbi Residual integrated viral DNA after hepadnavirus clearance by nucleoside analog therapy
    Jesse Summers
    Department of Molecular Genetics and Microbiology, University of New Mexico, Albuquerque, NM 87131, USA
    Proc Natl Acad Sci U S A 101:638-40. 2004
    ..Our results indicate that genetic changes from this damage remain in the liver even while virus infection is cleared and argue for early antiviral intervention in chronic hepatitis...
  2. ncbi Examining the theory of error catastrophe
    Jesse Summers
    Department of Molecular Genetics and Microbiology, University of New Mexico, Albuquerque, NM 87131, USA
    J Virol 80:20-6. 2006
  3. ncbi Rapid production of neutralizing antibody leads to transient hepadnavirus infection
    Yong-Yuan Zhang
    Department of Molecular Genetics and Microbiology, University of New Mexico School of Medicine, Albuquerque, New Mexico 87131, USA
    J Virol 78:1195-201. 2004
    ....
  4. ncbi Single-cell analysis of covalently closed circular DNA copy numbers in a hepadnavirus-infected liver
    Yong-Yuan Zhang
    Department of Molecular Genetics and Microbiology, University of New Mexico, 915 Camino de Salud Northeast, Albuquerque, NM 87131, USA
    Proc Natl Acad Sci U S A 100:12372-7. 2003
    ..We infer from the results that infected hepatocytes express virus at different levels and that during cell division it is possible to segregate cells containing no cccDNA...
  5. ncbi Hepatocyte turnover during resolution of a transient hepadnaviral infection
    Jesse Summers
    Department of Molecular Genetics and Microbiology, University of New Mexico, Albuquerque, NM 87131, USA
    Proc Natl Acad Sci U S A 100:11652-9. 2003
    ..Our results indicated that during resolution of the transient infections a large fraction of the infected hepatocyte population was killed and replaced by hepatocyte cell division...
  6. ncbi Genomic DNA double-strand breaks are targets for hepadnaviral DNA integration
    Colin A Bill
    Department of Molecular Genetics and Microbiology, University of New Mexico, 915 Camino de Salud NE, Albuquerque, NM 87131, USA
    Proc Natl Acad Sci U S A 101:11135-40. 2004
    ..The results suggest that integration of hepadnaviral DNA in infected livers occurs at sites of DNA damage and may indicate the presence of more widespread genetic changes beyond that caused by viral DNA integration itself [corrected]...
  7. ncbi Age-related differences in amplification of covalently closed circular DNA at early times after duck hepatitis B virus infection of ducks
    Yong Yuan Zhang
    Department of Molecular Genetics and Microbiology, University of New Mexico School of Medicine, Albuquerque, 87131, USA
    J Virol 79:9896-903. 2005
    ....
  8. ncbi Clonal expansion of hepatocytes during chronic woodchuck hepatitis virus infection
    William S Mason
    Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, PA 19111, USA
    Proc Natl Acad Sci U S A 102:1139-44. 2005
    ..The results provide evidence for a large amount of hepatocyte proliferation and selection having occurred during the period of chronic WHV infection ( approximately 1.5 years) in these animals...

Research Grants5

  1. GENERATION/EMERGENCE OF VARIANT IN HEPADNAVIRUS INFECTON
    Jesse Summers; Fiscal Year: 2004
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