Research Topics
| David L SultzerSummaryAffiliation: University of California Country: USA Publications
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Detail Information
Publications
Subcortical hyperintensities in Alzheimer's disease: associated clinical and metabolic findingsDavid L Sultzer
Departments of Psychiatry and Biobehavioral Sciences, University of California Los Angeles, USA
J Neuropsychiatry Clin Neurosci 14:262-9. 2002..These preliminary findings indicate that subcortical MRI hyperintensities may play a role in the pathophysiology and clinical expression of Alzheimer's disease...
Delusional thoughts and regional frontal/temporal cortex metabolism in Alzheimer's diseaseDavid L Sultzer
Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine at UCLA, USA
Am J Psychiatry 160:341-9. 2003..In this study the authors examined the relationship between delusional thoughts and regional cortical metabolism in patients with Alzheimer's disease...
Clinical symptom responses to atypical antipsychotic medications in Alzheimer's disease: phase 1 outcomes from the CATIE-AD effectiveness trialDavid L Sultzer
Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA
Am J Psychiatry 165:844-54. 2008..The study measured the effects of atypical antipsychotics on psychiatric and behavioral symptoms in patients with Alzheimer's disease and psychosis or agitated behavior...
Psychosis and antipsychotic medications in Alzheimer's disease: clinical management and research perspectivesDavid L Sultzer
Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine at UCLA, and Gero Neuropsychiatry Division, VA Greater Los Angeles Healthcare System, Los Angeles, CA 90073, USA
Dement Geriatr Cogn Disord 17:78-90. 2004..In particular, studies to compare how individual symptoms respond to different medications, and to examine how to best manage overlapping symptoms or incomplete treatment response are needed...
Effect of memantine treatment on regional cortical metabolism in Alzheimer's diseaseDavid L Sultzer
Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine, UCLA, CA, USA
Am J Geriatr Psychiatry 18:606-14. 2010..Preclinical studies have demonstrated the effect of memantine on neuroreceptors and cell physiology, although the impact of treatment on cortical activity in vivo is not known...
Cognitive effects of atypical antipsychotic medications in patients with Alzheimer's disease: outcomes from CATIE-ADCheryl L P Vigen
Department of Preventive Medicine, Keck School of Medicine, Universityof Southern California, Los Angeles, CA 90033, USA
Am J Psychiatry 168:831-9. 2011..The authors assessed the effects of time and treatment on neuropsychological functioning during the Clinical Antipsychotic Trials of Intervention Effectiveness-Alzheimer's Disease study (CATIE-AD)...
Metabolic changes associated with second-generation antipsychotic use in Alzheimer's disease patients: the CATIE-AD studyLing Zheng
Department of Psychiatry and Behavioral Sciences, Keck School of Medicine, University of Southern California, Los Angeles, USA
Am J Psychiatry 166:583-90. 2009..Elderly patients with Alzheimer's disease are frequently treated with these antipsychotics, but limited data are available on their metabolic effects...
Executive deficits and regional brain metabolism in Alzheimer's diseaseBenjamin K P Woo
Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, CA, USA
Int J Geriatr Psychiatry 25:1150-8. 2010..This study examined regional brain hypometabolism associated with executive dysfunction in patients with AD...
Effectiveness of atypical antipsychotic drugs in patients with Alzheimer's diseaseLon S Schneider
Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
N Engl J Med 355:1525-38. 2006..We assessed the effectiveness of atypical antipsychotic drugs in outpatients with Alzheimer's disease...
Frontal lobe hypometabolism and impaired insight in Alzheimer diseaseDylan G Harwood
Neuropsychiatric Institute and Hospital, Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine, Univ. of California, Los Angeles, CA, USA
Am J Geriatr Psychiatry 13:934-41. 2005....
The neural correlates of naming and fluency deficits in Alzheimer's disease: an FDG-PET studyRebecca J Melrose
Clinical Neurosciences Research Lab, VA Greater Los Angeles Healthcare System, Los Angeles, CA, USA
Int J Geriatr Psychiatry 24:885-93. 2009..To examine the neural processes associated with language deficits in Alzheimer's disease (AD), and in particular to elucidate the correlates of confrontation naming and word retrieval impairments...
Neuropsychological and neuroimaging markers in early versus late-onset Alzheimer's diseaseNatalie C Kaiser
VA Greater Los Angeles Healthcare System, Los Angeles, CA 90073, USA
Am J Alzheimers Dis Other Demen 27:520-9. 2012..Yet, the literature indicates EOAD may have less hippocampal-memory presentations and more focal neocortical localization early in the disease...
Cerebral metabolism, cognition, and functional abilities in Alzheimer diseaseRebecca J Melrose
Brain, Behavior, and Aging Research Center, VA Greater Los Angeles Healthcare System, CA, USA
J Geriatr Psychiatry Neurol 24:127-34. 2011..Findings suggest that hypometabolism of right sided brain regions involved in executive functioning, visuospatial processing, attention, and working memory underlie functional impairments in patients with AD...
Content-specific delusions from right caudate lacunar stroke: association with prefrontal hypometabolismAaron M McMurtray
Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, CA, USA
J Neuropsychiatry Clin Neurosci 20:62-7. 2008..These patients suggest an etiological relationship between alterations in inferior prefrontal functions and the development of content-specific delusions...
Positron emission tomography metabolic correlates of apathy in Alzheimer diseaseGad A Marshall
Department of Neurology, University of California, Los Angeles, CA, USA
Arch Neurol 64:1015-20. 2007....
Memory impairment among primary care veteransJoshua Chodosh
VA Greater Los Angeles Geriatric Research Education and Clinical Center, Sepulveda, CA, USA
Aging Ment Health 11:444-50. 2007..Memory impairment is common among older primary care patients without diagnosed dementia. Knowing patients' concerns about memory impairment and their desire to discuss these concerns may facilitate cognitive screening in this setting...
Association between cerebral metabolism and Rey-Osterrieth Complex Figure Test performance in Alzheimer's diseaseRebecca J Melrose
Brain, Behavior and Aging Research Center, VA Greater Los Angeles Healthcare System, Los Angeles, CA, USA
J Clin Exp Neuropsychol 35:246-58. 2013..The copy approach correlated with right lateral temporal cortex. The ROCF appears reflective of posterior temporal-parietal cortex functioning, highlighting the role of visuospatial processing in constructional abilities in AD...
The relationship between cognitive impairment and diabetes self-management in a population-based community sample of older adults with Type 2 diabetesDenise G Feil
Department of Psychiatry and Biobehavioral Sciences, Greater Los Angeles VA Healthcare System, West L A Veterans Health Care Center, UCLA, 11301 Wilshire Blvd, Bldg 401 116 AE, Los Angeles, CA 90073, USA
J Behav Med 35:190-9. 2012..01). Cognitive impairment is associated with worse self-care and may pose challenges to diabetic older persons, notably in diet and exercise. Cognitive screening may be indicated in this high risk group...
Valproate-induced hyperammonemia as a cause of altered mental statusDenise Feil
Division of Geriatric Psychiatry, VA Greater Los Angeles Healthcare System, CA 90073, USA
Am J Geriatr Psychiatry 10:476-8. 2002..They discuss this underrecognized complication of valproate use and the implications for treating elderly patients, in whom valproate use is increasing...
"Life is not worth living": hopelessness in Alzheimer's diseaseDylan G Harwood
Mental Health Services, VA Greater Los Angeles Healthcare System, California 90073, USA
J Geriatr Psychiatry Neurol 15:38-43. 2002..These thoughts appear to be related to the subjective expressions of depression and anxiety rather than the neurovegetative or affective signs and are more prominent among patients with greater deficit awareness...
Anxiety and regional cortical glucose metabolism in patients with Alzheimer's diseaseHiroshi Hashimoto
Department of Neuropsychiatry, Osaka City University Medical School, 1 4 3 Asahi machi, Abeno Ku, Osaka City, Osaka 545 8585, Japan
J Neuropsychiatry Clin Neurosci 18:521-8. 2006..Functional activity changes in distinct regions of the cortex contribute to the expression of anxiety in Alzheimer's disease...
Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE): Alzheimer's disease trialLon S Schneider
Department of Psychiatry and the Behavioral Sciences, Keck School of Medicine, University of Southern California, Los Angeles 90033, USA
Schizophr Bull 29:57-72. 2003....
