David L Sultzer

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Clinical symptom responses to atypical antipsychotic medications in Alzheimer's disease: phase 1 outcomes from the CATIE-AD effectiveness trial
    David L Sultzer
    Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA
    Am J Psychiatry 165:844-54. 2008
  2. ncbi request reprint Subcortical hyperintensities in Alzheimer's disease: associated clinical and metabolic findings
    David L Sultzer
    Departments of Psychiatry and Biobehavioral Sciences, University of California Los Angeles, USA
    J Neuropsychiatry Clin Neurosci 14:262-9. 2002
  3. ncbi request reprint Delusional thoughts and regional frontal/temporal cortex metabolism in Alzheimer's disease
    David L Sultzer
    Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine at UCLA, USA
    Am J Psychiatry 160:341-9. 2003
  4. ncbi request reprint Psychosis and antipsychotic medications in Alzheimer's disease: clinical management and research perspectives
    David L Sultzer
    Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine at UCLA, and Gero Neuropsychiatry Division, VA Greater Los Angeles Healthcare System, Los Angeles, CA 90073, USA
    Dement Geriatr Cogn Disord 17:78-90. 2004
  5. doi request reprint Effect of memantine treatment on regional cortical metabolism in Alzheimer's disease
    David L Sultzer
    Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine, UCLA, CA, USA
    Am J Geriatr Psychiatry 18:606-14. 2010
  6. pmc Cognitive effects of atypical antipsychotic medications in patients with Alzheimer's disease: outcomes from CATIE-AD
    Cheryl L P Vigen
    Department of Preventive Medicine, Keck School of Medicine, Universityof Southern California, Los Angeles, CA 90033, USA
    Am J Psychiatry 168:831-9. 2011
  7. pmc Metabolic changes associated with second-generation antipsychotic use in Alzheimer's disease patients: the CATIE-AD study
    Ling Zheng
    Department of Psychiatry and Behavioral Sciences, Keck School of Medicine, University of Southern California, Los Angeles, USA
    Am J Psychiatry 166:583-90. 2009
  8. doi request reprint Executive deficits and regional brain metabolism in Alzheimer's disease
    Benjamin K P Woo
    Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, CA, USA
    Int J Geriatr Psychiatry 25:1150-8. 2010
  9. ncbi request reprint Effectiveness of atypical antipsychotic drugs in patients with Alzheimer's disease
    Lon S Schneider
    Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
    N Engl J Med 355:1525-38. 2006
  10. ncbi request reprint Frontal lobe hypometabolism and impaired insight in Alzheimer disease
    Dylan G Harwood
    Neuropsychiatric Institute and Hospital, Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine, Univ of California, Los Angeles, CA, USA
    Am J Geriatr Psychiatry 13:934-41. 2005

Detail Information

Publications22

  1. pmc Clinical symptom responses to atypical antipsychotic medications in Alzheimer's disease: phase 1 outcomes from the CATIE-AD effectiveness trial
    David L Sultzer
    Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA
    Am J Psychiatry 165:844-54. 2008
    ..The study measured the effects of atypical antipsychotics on psychiatric and behavioral symptoms in patients with Alzheimer's disease and psychosis or agitated behavior...
  2. ncbi request reprint Subcortical hyperintensities in Alzheimer's disease: associated clinical and metabolic findings
    David L Sultzer
    Departments of Psychiatry and Biobehavioral Sciences, University of California Los Angeles, USA
    J Neuropsychiatry Clin Neurosci 14:262-9. 2002
    ..These preliminary findings indicate that subcortical MRI hyperintensities may play a role in the pathophysiology and clinical expression of Alzheimer's disease...
  3. ncbi request reprint Delusional thoughts and regional frontal/temporal cortex metabolism in Alzheimer's disease
    David L Sultzer
    Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine at UCLA, USA
    Am J Psychiatry 160:341-9. 2003
    ..In this study the authors examined the relationship between delusional thoughts and regional cortical metabolism in patients with Alzheimer's disease...
  4. ncbi request reprint Psychosis and antipsychotic medications in Alzheimer's disease: clinical management and research perspectives
    David L Sultzer
    Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine at UCLA, and Gero Neuropsychiatry Division, VA Greater Los Angeles Healthcare System, Los Angeles, CA 90073, USA
    Dement Geriatr Cogn Disord 17:78-90. 2004
    ..In particular, studies to compare how individual symptoms respond to different medications, and to examine how to best manage overlapping symptoms or incomplete treatment response are needed...
  5. doi request reprint Effect of memantine treatment on regional cortical metabolism in Alzheimer's disease
    David L Sultzer
    Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine, UCLA, CA, USA
    Am J Geriatr Psychiatry 18:606-14. 2010
    ..Preclinical studies have demonstrated the effect of memantine on neuroreceptors and cell physiology, although the impact of treatment on cortical activity in vivo is not known...
  6. pmc Cognitive effects of atypical antipsychotic medications in patients with Alzheimer's disease: outcomes from CATIE-AD
    Cheryl L P Vigen
    Department of Preventive Medicine, Keck School of Medicine, Universityof Southern California, Los Angeles, CA 90033, USA
    Am J Psychiatry 168:831-9. 2011
    ..The authors assessed the effects of time and treatment on neuropsychological functioning during the Clinical Antipsychotic Trials of Intervention Effectiveness-Alzheimer's Disease study (CATIE-AD)...
  7. pmc Metabolic changes associated with second-generation antipsychotic use in Alzheimer's disease patients: the CATIE-AD study
    Ling Zheng
    Department of Psychiatry and Behavioral Sciences, Keck School of Medicine, University of Southern California, Los Angeles, USA
    Am J Psychiatry 166:583-90. 2009
    ..Elderly patients with Alzheimer's disease are frequently treated with these antipsychotics, but limited data are available on their metabolic effects...
  8. doi request reprint Executive deficits and regional brain metabolism in Alzheimer's disease
    Benjamin K P Woo
    Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, CA, USA
    Int J Geriatr Psychiatry 25:1150-8. 2010
    ..This study examined regional brain hypometabolism associated with executive dysfunction in patients with AD...
  9. ncbi request reprint Effectiveness of atypical antipsychotic drugs in patients with Alzheimer's disease
    Lon S Schneider
    Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
    N Engl J Med 355:1525-38. 2006
    ..We assessed the effectiveness of atypical antipsychotic drugs in outpatients with Alzheimer's disease...
  10. ncbi request reprint Frontal lobe hypometabolism and impaired insight in Alzheimer disease
    Dylan G Harwood
    Neuropsychiatric Institute and Hospital, Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine, Univ of California, Los Angeles, CA, USA
    Am J Geriatr Psychiatry 13:934-41. 2005
    ..The authors examined the relationship between impaired insight regarding cognitive and functional deficits and frontal cortex hypometabolism in 41 patients with Alzheimer disease (AD)...
  11. pmc The neural correlates of naming and fluency deficits in Alzheimer's disease: an FDG-PET study
    Rebecca J Melrose
    Clinical Neurosciences Research Lab, VA Greater Los Angeles Healthcare System, Los Angeles, CA, USA
    Int J Geriatr Psychiatry 24:885-93. 2009
    ..To examine the neural processes associated with language deficits in Alzheimer's disease (AD), and in particular to elucidate the correlates of confrontation naming and word retrieval impairments...
  12. doi request reprint Neuropsychological and neuroimaging markers in early versus late-onset Alzheimer's disease
    Natalie C Kaiser
    VA Greater Los Angeles Healthcare System, Los Angeles, CA 90073, USA
    Am J Alzheimers Dis Other Demen 27:520-9. 2012
    ..Yet, the literature indicates EOAD may have less hippocampal-memory presentations and more focal neocortical localization early in the disease...
  13. doi request reprint Cerebral metabolism, cognition, and functional abilities in Alzheimer disease
    Rebecca J Melrose
    Brain, Behavior, and Aging Research Center, VA Greater Los Angeles Healthcare System, CA, USA
    J Geriatr Psychiatry Neurol 24:127-34. 2011
    ..Findings suggest that hypometabolism of right sided brain regions involved in executive functioning, visuospatial processing, attention, and working memory underlie functional impairments in patients with AD...
  14. doi request reprint Content-specific delusions from right caudate lacunar stroke: association with prefrontal hypometabolism
    Aaron M McMurtray
    Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, CA, USA
    J Neuropsychiatry Clin Neurosci 20:62-7. 2008
    ..These patients suggest an etiological relationship between alterations in inferior prefrontal functions and the development of content-specific delusions...
  15. ncbi request reprint Positron emission tomography metabolic correlates of apathy in Alzheimer disease
    Gad A Marshall
    Department of Neurology, University of California, Los Angeles, CA, USA
    Arch Neurol 64:1015-20. 2007
    ....
  16. pmc Association between cerebral metabolism and Rey-Osterrieth Complex Figure Test performance in Alzheimer's disease
    Rebecca J Melrose
    Brain, Behavior and Aging Research Center, VA Greater Los Angeles Healthcare System, Los Angeles, CA, USA
    J Clin Exp Neuropsychol 35:246-58. 2013
    ..The copy approach correlated with right lateral temporal cortex. The ROCF appears reflective of posterior temporal-parietal cortex functioning, highlighting the role of visuospatial processing in constructional abilities in AD...
  17. ncbi request reprint Memory impairment among primary care veterans
    Joshua Chodosh
    VA Greater Los Angeles Geriatric Research Education and Clinical Center, Sepulveda, CA, USA
    Aging Ment Health 11:444-50. 2007
    ..Memory impairment is common among older primary care patients without diagnosed dementia. Knowing patients' concerns about memory impairment and their desire to discuss these concerns may facilitate cognitive screening in this setting...
  18. doi request reprint The relationship between cognitive impairment and diabetes self-management in a population-based community sample of older adults with Type 2 diabetes
    Denise G Feil
    Department of Psychiatry and Biobehavioral Sciences, Greater Los Angeles VA Healthcare System, West L A Veterans Health Care Center, UCLA, 11301 Wilshire Blvd, Bldg 401 116 AE, Los Angeles, CA 90073, USA
    J Behav Med 35:190-9. 2012
    ..01). Cognitive impairment is associated with worse self-care and may pose challenges to diabetic older persons, notably in diet and exercise. Cognitive screening may be indicated in this high risk group...
  19. ncbi request reprint Valproate-induced hyperammonemia as a cause of altered mental status
    Denise Feil
    Division of Geriatric Psychiatry, VA Greater Los Angeles Healthcare System, CA 90073, USA
    Am J Geriatr Psychiatry 10:476-8. 2002
    ..They discuss this underrecognized complication of valproate use and the implications for treating elderly patients, in whom valproate use is increasing...
  20. ncbi request reprint "Life is not worth living": hopelessness in Alzheimer's disease
    Dylan G Harwood
    Mental Health Services, VA Greater Los Angeles Healthcare System, California 90073, USA
    J Geriatr Psychiatry Neurol 15:38-43. 2002
    ..These thoughts appear to be related to the subjective expressions of depression and anxiety rather than the neurovegetative or affective signs and are more prominent among patients with greater deficit awareness...
  21. ncbi request reprint Anxiety and regional cortical glucose metabolism in patients with Alzheimer's disease
    Hiroshi Hashimoto
    Department of Neuropsychiatry, Osaka City University Medical School, 1 4 3 Asahi machi, Abeno Ku, Osaka City, Osaka 545 8585, Japan
    J Neuropsychiatry Clin Neurosci 18:521-8. 2006
    ..Functional activity changes in distinct regions of the cortex contribute to the expression of anxiety in Alzheimer's disease...
  22. ncbi request reprint Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE): Alzheimer's disease trial
    Lon S Schneider
    Department of Psychiatry and the Behavioral Sciences, Keck School of Medicine, University of Southern California, Los Angeles 90033, USA
    Schizophr Bull 29:57-72. 2003
    ....