Genomes and Genes


Dhivya R Sudhan


Affiliation: University of Florida
Country: USA


  1. Sudhan D, Siemann D. Cathepsin L inhibition by the small molecule KGP94 suppresses tumor microenvironment enhanced metastasis associated cell functions of prostate and breast cancer cells. Clin Exp Metastasis. 2013;30:891-902 pubmed publisher
    ..Importantly, KGP94 treatment led to marked attenuation of tumor cell invasion and migration under both normal and aberrant microenvironmental conditions suggesting that it may have significant utility as an anti-metastatic agent. ..
  2. Sudhan D, Rabaglino M, Wood C, Siemann D. Cathepsin L in tumor angiogenesis and its therapeutic intervention by the small molecule inhibitor KGP94. Clin Exp Metastasis. 2016;33:461-73 pubmed publisher
    ..Collectively, these data indicate that CTSL is an important contributor to tumor angiogenesis and that the CTSL inhibition may have therapeutic utility in the treatment of breast cancer patients. ..