M A Suckow

Summary

Affiliation: University of Notre Dame
Country: USA

Publications

  1. doi request reprint Bupivacaine-enhanced small intestinal submucosa biomaterial as a hernia repair device
    Mark A Suckow
    Freimann Life Science Center, University of Notre Dame, Notre Dame, IN 46556, USA
    J Biomater Appl 27:231-7. 2012
  2. ncbi request reprint Prevention of human PC-346C prostate cancer growth in mice by a xenogeneic tissue vaccine
    Mark A Suckow
    Freimann Life Science Center, University of Notre Dame, Notre Dame, IN 46556, USA
    Cancer Immunol Immunother 56:1275-83. 2007
  3. ncbi request reprint Repair of experimental Achilles tenotomy with porcine renal capsule material in a rat model
    M A Suckow
    University of Notre Dame, 400 Freimann Life Science Center, Notre Dame, IN 46556, USA
    J Mater Sci Mater Med 18:1105-10. 2007
  4. pmc Field trial of a Pasteurella multocida extract vaccine in rabbits
    Mark A Suckow
    Laboratory Animal Program, Purdue University, West Lafayette, IN, USA
    J Am Assoc Lab Anim Sci 47:18-21. 2008
  5. doi request reprint Tissue vaccines for cancer
    Mark A Suckow
    University of Notre Dame, Freimann Life Science Center, Notre Dame, IN, USA
    Expert Rev Vaccines 6:925-37. 2007
  6. ncbi request reprint Immunization with a tissue vaccine enhances the effect of irradiation on prostate tumors
    Mark A Suckow
    Freimann Life Science Center, University of Notre Dame, Notre Dame, IN 46556, USA
    In Vivo 22:171-7. 2008
  7. doi request reprint Inhibition of prostate cancer metastasis by administration of a tissue vaccine
    Mark A Suckow
    Freimann Life Science Center, University of Notre Dame, Notre Dame, IN 46530, USA
    Clin Exp Metastasis 25:913-8. 2008
  8. ncbi request reprint Use of an extracellular matrix material as a vaccine carrier and adjuvant
    Mark A Suckow
    Freimann Life Science Center, University of Notre Dame, Notre Dame, IN 46556, USA
    Anticancer Res 28:2529-34. 2008
  9. pmc PAIII prostate tumors express prostate specific antigen (PSA) in Lobund-Wistar rats
    Mark A Suckow
    Freimann Life Science Center, University of Notre Dame, Notre Dame, Indiana 46556, USA
    Can J Vet Res 73:39-41. 2009
  10. doi request reprint Addition of nimesulide to small intestinal submucosa biomaterial inhibits postsurgical adhesiogenesis in rats
    Mark A Suckow
    Freimann Life Science Center, University of Notre Dame, Notre Dame, IN 46556, USA
    J Biomed Mater Res B Appl Biomater 93:18-23. 2010

Collaborators

Detail Information

Publications32

  1. doi request reprint Bupivacaine-enhanced small intestinal submucosa biomaterial as a hernia repair device
    Mark A Suckow
    Freimann Life Science Center, University of Notre Dame, Notre Dame, IN 46556, USA
    J Biomater Appl 27:231-7. 2012
    ..In summary, bupivacaine is readily elaborated from SIS-B; and impregnation of SIS with bupivacaine does not substantially alter the biocompatibility of the biomaterial or its mechanical strength following implantation...
  2. ncbi request reprint Prevention of human PC-346C prostate cancer growth in mice by a xenogeneic tissue vaccine
    Mark A Suckow
    Freimann Life Science Center, University of Notre Dame, Notre Dame, IN 46556, USA
    Cancer Immunol Immunother 56:1275-83. 2007
    ..In summary, the results suggest that use of a xenogeneic tissue vaccine can stimulate protective immunity against human prostate cancer cells...
  3. ncbi request reprint Repair of experimental Achilles tenotomy with porcine renal capsule material in a rat model
    M A Suckow
    University of Notre Dame, 400 Freimann Life Science Center, Notre Dame, IN 46556, USA
    J Mater Sci Mater Med 18:1105-10. 2007
    ..The results show that RCM is equivalent to SIS as a material for repair of Achilles tendon injury and merits further study in other tendon injury models...
  4. pmc Field trial of a Pasteurella multocida extract vaccine in rabbits
    Mark A Suckow
    Laboratory Animal Program, Purdue University, West Lafayette, IN, USA
    J Am Assoc Lab Anim Sci 47:18-21. 2008
    ..In summary, PTE can be used to stimulate protective immunity to a heterologous strain of P. multocida, with stronger immunity generated by SC than IN vaccination...
  5. doi request reprint Tissue vaccines for cancer
    Mark A Suckow
    University of Notre Dame, Freimann Life Science Center, Notre Dame, IN, USA
    Expert Rev Vaccines 6:925-37. 2007
    ..For these reasons, the idea that tissue vaccines for cancer have potentially great utility has merit and should be explored further...
  6. ncbi request reprint Immunization with a tissue vaccine enhances the effect of irradiation on prostate tumors
    Mark A Suckow
    Freimann Life Science Center, University of Notre Dame, Notre Dame, IN 46556, USA
    In Vivo 22:171-7. 2008
    ..Immunization with a tissue vaccine prior to radiation treatment enhances the therapeutic effect of radiation...
  7. doi request reprint Inhibition of prostate cancer metastasis by administration of a tissue vaccine
    Mark A Suckow
    Freimann Life Science Center, University of Notre Dame, Notre Dame, IN 46530, USA
    Clin Exp Metastasis 25:913-8. 2008
    ..These results suggest that tissue vaccines may be useful for the treatment of prostate cancer...
  8. ncbi request reprint Use of an extracellular matrix material as a vaccine carrier and adjuvant
    Mark A Suckow
    Freimann Life Science Center, University of Notre Dame, Notre Dame, IN 46556, USA
    Anticancer Res 28:2529-34. 2008
    ....
  9. pmc PAIII prostate tumors express prostate specific antigen (PSA) in Lobund-Wistar rats
    Mark A Suckow
    Freimann Life Science Center, University of Notre Dame, Notre Dame, Indiana 46556, USA
    Can J Vet Res 73:39-41. 2009
    ..All 5 PAIII tumors demonstrated labeling for PSA, supporting a prostatic origin for the PAIII cell line...
  10. doi request reprint Addition of nimesulide to small intestinal submucosa biomaterial inhibits postsurgical adhesiogenesis in rats
    Mark A Suckow
    Freimann Life Science Center, University of Notre Dame, Notre Dame, IN 46556, USA
    J Biomed Mater Res B Appl Biomater 93:18-23. 2010
    ..In conclusion, addition of the nonsteroidal anti-inflammatory, COX-2 selective drug, NM, to SIS attenuates adhesion extent and tenacity when compared with surgical placement of SIS or PPM alone...
  11. ncbi request reprint Tissue distribution of fetal liver cells following in utero transplantation in mice
    Mark A Suckow
    W M Keck Center for Transgene Research, University of Notre Dame, Notre Dame, IN 46556, USA
    Exp Biol Med (Maywood) 230:860-4. 2005
    ..In summary, the possibility that cells administered in utero may inadvertently colonize nontarget tissues suggests that clinical application of this method will need to be approached with diligence...
  12. ncbi request reprint The anti-ischemia agent ranolazine promotes the development of intestinal tumors in APC(Min/+) mice
    Mark A Suckow
    Walther Cancer Center, 400 Freimann Life Science Center, University of Notre Dame, Notre Dame, IN 46556, USA
    Cancer Lett 209:165-9. 2004
    ..Tumors from drug-treated mice were also more dysplastic and invasive than those from untreated mice. These findings have implications for the use of ranolazine in patients with a history of malignant neoplasms or adenomatous polyps...
  13. ncbi request reprint Susceptibility of Lobund-Wistar x Copenhagen hybrid rats to autochthonous prostate carcinogenesis
    Mark A Suckow
    Lobund Laboratory, University of Notre Dame, Notre Dame, IN 46556, USA
    Prostate 64:203-8. 2005
    ..Transplantation of the Dunning R-3327 prostate tumor cell line is a common model of prostate cancer, though the rat strain (Copenhagen) from which the cell line was derived is resistant to spontaneous and chemically induced prostate cancer...
  14. ncbi request reprint Prevention of de novo prostate cancer by immunization with tumor-derived vaccines
    Mark A Suckow
    Lobund Institute, University of Notre Dame, 400 Freimann Life Science Center, Notre Dame, IN, 46556, USA
    Cancer Immunol Immunother 54:571-6. 2005
    ..These results demonstrate the possibility that prostate cancer can be prevented by immunization with vaccines based on whole tumor-derived vaccines...
  15. pmc Induction of protective immunity in rabbits by coadministration of inactivated Pasteurella multocida toxin and potassium thiocyanate extract
    L Z Jarvinen
    Veterinary Pathobiology, Purdue University, West Lafayette, Indiana 47907, USA
    Infect Immun 66:3788-95. 1998
    ..Rabbits in the control groups had moderate to severe liver and lung infections. This study indicates that i.n. immunization with both PMT and CN induces an effective response against homologous P. multocida challenge...
  16. ncbi request reprint Use of porcine renal capsule matrix as a full-thickness dermal wound-healing material in rats
    M A Suckow
    I Freimann Life Science Center, University of Notre Dame, Notre Dame, Indiana, USA
    J Wound Care 14:137-40. 2005
    ..To compare the utility of porcine renal capsule matrix (RCM) with porcine small intestinal mucosa (SIS) in a rat full-thickness skin wound model...
  17. ncbi request reprint Small intestinal submucosa does not promote PAIII tumor growth in Lobund-Wistar rats
    Jason P Hodde
    Cook Biotech Incorporated, 3055 Kent Avenue, West Lafayette, Indiana, USA
    J Surg Res 120:189-94. 2004
    ..The effect of SIS on the ability of neoplastic (prostate adenocarcinoma) cells to establish, grow, and metastasize was examined in Lobund-Wistar (L-W) rats...
  18. ncbi request reprint Dietary prevention of hormone refractory prostate cancer in Lobund-Wistar rats: a review of studies in a relevant animal model
    Morris Pollard
    Lobund Institute, University of Notre Dame, Notre Dame, Indiana, USA
    Comp Med 56:461-7. 2006
    ..The accumulated data indicate that soy-based diets are effective in the prevention of prostate cancer...
  19. ncbi request reprint Immunization of rabbits against a bacterial pathogen with an alginate microparticle vaccine
    Mark A Suckow
    400 Freimann Life Science Center, University of Notre Dame, Notre Dame, IN 46556, USA
    J Control Release 85:227-35. 2002
    ..multocida recovered from the lungs and nasopharynx following an intranasal challenge. These results demonstrate that PTE incorporated into alginate microparticles and administered orally is immunogenic and confers protective immunity...
  20. pmc Fas/CD95 deficiency in ApcMin/+ mice increases intestinal tumor burden
    Hector Guillen-Ahlers
    W M Keck Center for Transgene Research, University of Notre Dame, Notre Dame, Indiana, United States of America
    PLoS ONE 5:e9070. 2010
    ..Fas, a member of the tumor necrosis family, is responsible for initiating the apoptotic pathway when bound to its ligand, Fas-L. Defects in the Fas-mediated apoptotic pathway have been reported in colorectal cancer...
  21. pmc Synthesis and evaluation of 5-lipoxygenase translocation inhibitors from acylnitroso hetero-Diels-Alder cycloadducts
    Joshua K Bolger
    Department of Chemistry and Biochemistry, 251 Nieuwland Science Hall, University of Notre Dame, Notre Dame, IN 46556, USA
    Org Biomol Chem 9:2999-3010. 2011
    ..Additionally, the lead compound was tested in vivo in an established colon cancer model and showed very encouraging anti-tumorogenic properties...
  22. ncbi request reprint Hormone-refractory prostate cancer in the Lobund-Wistar rat
    Morris Pollard
    Lobund Institute, University of Notre Dame, Notre Dame, IN 46556, USA
    Exp Biol Med (Maywood) 230:520-6. 2005
    ..Both spontaneous and chemically induced autochthonous HRPC model systems serve as outstanding models for studies on the prevention and therapy of refractory cancer...
  23. ncbi request reprint Vaccination against prostate cancer using a live tissue factor deficient cell line in Lobund-Wistar rats
    Julie E Heinrich
    University of Notre Dame Biological Sciences, Notre Dame, IN, USA
    Cancer Immunol Immunother 56:725-30. 2007
    ..These results offer the intriguing possibility that the TFD PAIII vaccine is an effective system for the prevention and, possibly, the treatment of prostate cancer...
  24. ncbi request reprint Cathepsin E is a specific marker of dysplasia in APC mouse intestine
    Lizette Busquets
    Walther Cancer Center, Notre Dame, IN 46556, USA
    Tumour Biol 27:36-42. 2006
    ..These results authenticate the relationship between transcript abundance and protein levels in transformed tissue and suggest potential utility for catE as a marker for the inception and progression of intestinal cancers...
  25. pmc The characterization of mice with a targeted combined deficiency of protein c and factor XI
    J C Chan
    Department of Chemistry and Biochemistry, W M Keck Center for Transgene Research, and the Freimann Life Science Center, University of Notre Dame, Notre Dame, Indiana 46556, USA
    Am J Pathol 158:469-79. 2001
    ....
  26. pmc Optical imaging of mammary and prostate tumors in living animals using a synthetic near infrared zinc(II)-dipicolylamine probe for anionic cell surfaces
    Bryan A Smith
    Department of Chemistry and Biochemistry, 251 Nieuwland Science Hall, University of Notre Dame, Notre Dame, Indiana 46556, USA
    J Am Chem Soc 132:67-9. 2010
    ....
  27. pmc A potent gelatinase inhibitor with anti-tumor-invasive activity and its metabolic disposition
    Mijoon Lee
    Department of Chemistry and Biochemistry and Walther Cancer Research Center, University of Notre Dame, Notre Dame, IN 46556, USA
    Chem Biol Drug Des 73:189-202. 2009
    ..The metabolism of compound 2 involved hydroxylation at the alpha-methylene, which generates sulfinic acid, thiirane ring-opening, followed by methylation and oxidation, and cysteine conjugation of both the thiirane and phenyl rings...
  28. pmc Sulindac treatment alters collagen and matrilysin expression in adenomas of ApcMin/+ mice
    Hector Guillen-Ahlers
    W M Keck Center for Transgene Research, University of Notre Dame, Notre Dame, IN 46556, USA
    Carcinogenesis 29:1421-7. 2008
    ....
  29. ncbi request reprint Sebaceous adenocarcinoma of the external auditory canal in a New Zealand white rabbit
    M A Suckow
    Freimann Life Science Center, University of Notre Dame, Notre Dame, IN 46556, USA
    J Comp Pathol 127:301-3. 2002
    ..A single pulmonary mass had similar histological characteristics. This is the first such tumour reported in a rabbit...
  30. pmc ADP-ribosylation factor 6 regulates tumorigenic and invasive properties in vivo
    Vandhana Muralidharan-Chari
    Department of Biological Sciences, Freimann Life Science Center, and W M Keck Center for Transgene Research, University of Notre Dame, Notre Dame, Indiana, USA
    Cancer Res 69:2201-9. 2009
    ..These findings document an intricate role for ARF6 and the regulation of ERK activation in orchestrating mechanisms underlying melanoma growth, invasion, and metastases...
  31. doi request reprint Metabolism of (4-phenoxyphenylsulfonyl) methylthiirane, a selective gelatinase inhibitor
    Giuseppe Celenza
    Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, IN 46556, USA
    Chem Biol Drug Des 71:187-96. 2008
    ..The cysteine adducts arose through addition of glutathione to the thiirane ring. The molecule is extensively metabolized and..
  32. ncbi request reprint Use of mucosal immunization with porcine zona pellucida (PZP) in mice and rabbits
    Brent J Martin
    Division of Laboratory Animal Medicine, Medical University of Ohio, 3055 Arlington Avenue, Toledo, OH 43614, USA
    Anim Reprod Sci 93:372-8. 2006
    ..05). The study shows that porcine zona pellucida is not an effective mucosal antigen in small mammals...