Venkateswaran Subramanian

Summary

Affiliation: University of Kentucky
Country: USA

Publications

  1. pmc Calpain inhibition attenuates angiotensin II-induced abdominal aortic aneurysms and atherosclerosis in low-density lipoprotein receptor-deficient mice
    Venkateswaran Subramanian
    Saha Cardiovascular Research Center, University of Kentucky, Lexington, KY 40536 0509, USA
    J Cardiovasc Pharmacol 59:66-76. 2012
  2. pmc Regulation of peroxisome proliferator-activated receptor-γ by angiotensin II via transforming growth factor-β1-activated p38 mitogen-activated protein kinase in aortic smooth muscle cells
    Venkateswaran Subramanian
    Saha Cardiovascular Research Center, BBSRB, Rm B249, University of Kentucky, Lexington, KY 40536 0509, USA
    Arterioscler Thromb Vasc Biol 32:397-405. 2012
  3. pmc Endothelial cell-specific deficiency of Ang II type 1a receptors attenuates Ang II-induced ascending aortic aneurysms in LDL receptor-/- mice
    Debra L Rateri
    Saha Cardiovascular Research Center, BBSRB, Room 243, University of Kentucky, Lexington, KY 40536 0509, USA
    Circ Res 108:574-81. 2011
  4. pmc Urokinase-type plasminogen activator deficiency in bone marrow-derived cells augments rupture of angiotensin II-induced abdominal aortic aneurysms
    Haruhito A Uchida
    Saha Cardiovascular Research Center, University of Kentucky, Lexington, KY 40536 0509, USA
    Arterioscler Thromb Vasc Biol 31:2845-52. 2011
  5. pmc Pioglitazone-induced reductions in atherosclerosis occur via smooth muscle cell-specific interaction with PPAR{gamma}
    Venkateswaran Subramanian
    Saha Cardiovascular Research Center, BBSRB, Room B243, University of Kentucky, Lexington, KY 40536 0509, USA
    Circ Res 107:953-8. 2010
  6. pmc Angiotensin II induces a region-specific hyperplasia of the ascending aorta through regulation of inhibitor of differentiation 3
    A Phillip Owens
    Saha Cardiovascular Research Center, University of Kentucky, Lexington, KY 40536 0509, USA
    Circ Res 106:611-9. 2010
  7. pmc Deficiency of receptor-associated protein attenuates angiotensin II-induced atherosclerosis in hypercholesterolemic mice without influencing abdominal aortic aneurysms
    Shaoping Wang
    28th Division, Beijing An Zhen Hospital, Capital Medical University, Beijing 100029, China
    Atherosclerosis 220:375-80. 2012
  8. pmc Calpain-2 Compensation Promotes Angiotensin II-Induced Ascending and Abdominal Aortic Aneurysms in Calpain-1 Deficient Mice
    Venkateswaran Subramanian
    Saha Cardiovascular Research Center, University of Kentucky, Lexington, Kentucky, United States of America
    PLoS ONE 8:e72214. 2013

Collaborators

Detail Information

Publications8

  1. pmc Calpain inhibition attenuates angiotensin II-induced abdominal aortic aneurysms and atherosclerosis in low-density lipoprotein receptor-deficient mice
    Venkateswaran Subramanian
    Saha Cardiovascular Research Center, University of Kentucky, Lexington, KY 40536 0509, USA
    J Cardiovasc Pharmacol 59:66-76. 2012
    ..We conclude that calpain inhibition using BDA-410 attenuated AngII-induced AAA formation and atherosclerosis development in low-density lipoprotein receptor-/- mice...
  2. pmc Regulation of peroxisome proliferator-activated receptor-γ by angiotensin II via transforming growth factor-β1-activated p38 mitogen-activated protein kinase in aortic smooth muscle cells
    Venkateswaran Subramanian
    Saha Cardiovascular Research Center, BBSRB, Rm B249, University of Kentucky, Lexington, KY 40536 0509, USA
    Arterioscler Thromb Vasc Biol 32:397-405. 2012
    ..Therefore, the purpose of this study was to determine the mechanism of Ang II-mediated intracellular regulation of PPARγ in VSMCs...
  3. pmc Endothelial cell-specific deficiency of Ang II type 1a receptors attenuates Ang II-induced ascending aortic aneurysms in LDL receptor-/- mice
    Debra L Rateri
    Saha Cardiovascular Research Center, BBSRB, Room 243, University of Kentucky, Lexington, KY 40536 0509, USA
    Circ Res 108:574-81. 2011
    ..In agreement with this associative evidence, we have published recently that Ang II infusion induces aneurysmal pathology in the ascending aorta...
  4. pmc Urokinase-type plasminogen activator deficiency in bone marrow-derived cells augments rupture of angiotensin II-induced abdominal aortic aneurysms
    Haruhito A Uchida
    Saha Cardiovascular Research Center, University of Kentucky, Lexington, KY 40536 0509, USA
    Arterioscler Thromb Vasc Biol 31:2845-52. 2011
    ..Therefore, it is important to identify specific protease systems involved in extracellular matrix degradation during AAA formation. The present study determined the contribution of the urokinase system to AAA formation and rupture...
  5. pmc Pioglitazone-induced reductions in atherosclerosis occur via smooth muscle cell-specific interaction with PPAR{gamma}
    Venkateswaran Subramanian
    Saha Cardiovascular Research Center, BBSRB, Room B243, University of Kentucky, Lexington, KY 40536 0509, USA
    Circ Res 107:953-8. 2010
    ..Peroxisome proliferator-activated receptor (PPAR)γ agonists attenuate atherosclerosis and abdominal aortic aneurysms (AAAs). PPARγ, a nuclear receptor, is expressed on many cell types including smooth muscle cells (SMCs)...
  6. pmc Angiotensin II induces a region-specific hyperplasia of the ascending aorta through regulation of inhibitor of differentiation 3
    A Phillip Owens
    Saha Cardiovascular Research Center, University of Kentucky, Lexington, KY 40536 0509, USA
    Circ Res 106:611-9. 2010
    ..Angiotensin II (Ang II) has diverse effects on smooth muscle cells (SMCs). The diversity of effects may relate to the regional location of this cell type...
  7. pmc Deficiency of receptor-associated protein attenuates angiotensin II-induced atherosclerosis in hypercholesterolemic mice without influencing abdominal aortic aneurysms
    Shaoping Wang
    28th Division, Beijing An Zhen Hospital, Capital Medical University, Beijing 100029, China
    Atherosclerosis 220:375-80. 2012
    ....
  8. pmc Calpain-2 Compensation Promotes Angiotensin II-Induced Ascending and Abdominal Aortic Aneurysms in Calpain-1 Deficient Mice
    Venkateswaran Subramanian
    Saha Cardiovascular Research Center, University of Kentucky, Lexington, Kentucky, United States of America
    PLoS ONE 8:e72214. 2013
    ..Using BDA-410, an inhibitor of calpains, and calpain-1 genetic deficient mice, we examined the relative contribution of calpain isoforms in AngII-induced ascending and abdominal AA development...