J H Su

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint Neuronal DNA damage precedes tangle formation and is associated with up-regulation of nitrotyrosine in Alzheimer's disease brain
    J H Su
    Institute for Brain Aging and Dementia, University of California, Irvine, 92697 4540, USA
    Brain Res 774:193-9. 1997
  2. ncbi request reprint Plaque biogenesis in brain aging and Alzheimer's disease. II. Progressive transformation and developmental sequence of dystrophic neurites
    J H Su
    Institute for Brain Aging and Dementia, University of California Irvine, 92717 4550, USA
    Acta Neuropathol 96:463-71. 1998
  3. ncbi request reprint Activated caspase-3 expression in Alzheimer's and aged control brain: correlation with Alzheimer pathology
    J H Su
    Institute for Brain Aging and Dementia, University of California, Irvine, CA 92697 4540, USA
    Brain Res 898:350-7. 2001
  4. pmc Correlation between caspase activation and neurofibrillary tangle formation in Alzheimer's disease
    T T Rohn
    Institute for Brain Aging and Dementia, University of California at Irvine, 92697-4540, USA
    Am J Pathol 158:189-98. 2001
  5. ncbi request reprint Astrocytes degenerate in frontotemporal dementia: possible relation to hypoperfusion
    J A Martin
    Alzheimer s Disease Research Center, University of California at Irvine, Irvine, CA 92697 4540, USA
    Neurobiol Aging 22:195-207. 2001
  6. ncbi request reprint Parallel compensatory and pathological events associated with tau pathology in middle aged individuals with Down syndrome
    E Head
    Institute for Brain Aging and Dementia, University of California, Irvine, Irvine, California 92697 4540, USA
    J Neuropathol Exp Neurol 62:917-26. 2003
  7. ncbi request reprint Arsenite-induced nitric oxide generation is cell cycle-dependent and aberrant in NBS cells
    S S Yuan
    Department of Obstetrics and Gynecology, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan 807, Republic of China
    Toxicol In Vitro 17:139-43. 2003
  8. ncbi request reprint Altered p-JAK1 expression is associated with estrogen receptor status in breast infiltrating ductal carcinoma
    Y T Yeh
    Department of Medical Research and Department of Obstetrics and Gynecology, E Da Hospital, Kaohsiung, Taiwan, ROC
    Oncol Rep 17:35-9. 2007

Collaborators

Detail Information

Publications8

  1. ncbi request reprint Neuronal DNA damage precedes tangle formation and is associated with up-regulation of nitrotyrosine in Alzheimer's disease brain
    J H Su
    Institute for Brain Aging and Dementia, University of California, Irvine, 92697 4540, USA
    Brain Res 774:193-9. 1997
    ..These data suggest the hypothesis that the neurons with DNA damage in the absence of tangle formation may degenerate by tangle-independent mechanisms and that oxidative damage may contribute to such mechanisms in AD...
  2. ncbi request reprint Plaque biogenesis in brain aging and Alzheimer's disease. II. Progressive transformation and developmental sequence of dystrophic neurites
    J H Su
    Institute for Brain Aging and Dementia, University of California Irvine, 92717 4550, USA
    Acta Neuropathol 96:463-71. 1998
    ..These data suggest that dystrophic neurites can develop retrogradely from focal plaque damage to induce somatic and dendritic degeneration and potentially contribute to neurofibrillary tangle formation...
  3. ncbi request reprint Activated caspase-3 expression in Alzheimer's and aged control brain: correlation with Alzheimer pathology
    J H Su
    Institute for Brain Aging and Dementia, University of California, Irvine, CA 92697 4540, USA
    Brain Res 898:350-7. 2001
    ..These data suggest that activated caspase-3 may be a factor in functional decline and may have an important role in neuronal cell death and plaque formation in AD brain...
  4. pmc Correlation between caspase activation and neurofibrillary tangle formation in Alzheimer's disease
    T T Rohn
    Institute for Brain Aging and Dementia, University of California at Irvine, 92697-4540, USA
    Am J Pathol 158:189-98. 2001
    ..84). Taken together, these results provide evidence for the activation of apoptotic mechanisms in neurons in the AD brain and suggest that there is an association between NFT formation and the activation of apoptotic pathways in AD...
  5. ncbi request reprint Astrocytes degenerate in frontotemporal dementia: possible relation to hypoperfusion
    J A Martin
    Alzheimer s Disease Research Center, University of California at Irvine, Irvine, CA 92697 4540, USA
    Neurobiol Aging 22:195-207. 2001
    ..55, p < 0.05). Furthermore, areas of significant astrogliosis corresponded to areas of SPECT hypoperfusion, suggesting that astrocytes may be affected by or perhaps have a causal role in the disturbances of cerebral perfusion in FTD...
  6. ncbi request reprint Parallel compensatory and pathological events associated with tau pathology in middle aged individuals with Down syndrome
    E Head
    Institute for Brain Aging and Dementia, University of California, Irvine, Irvine, California 92697 4540, USA
    J Neuropathol Exp Neurol 62:917-26. 2003
    ..Thus, compensatory growth responses may occur in DS prior to extensive AD pathology and may be one mechanism underlying observations in PET studies of hypermetabolism in the entorhinal cortex of individuals with DS...
  7. ncbi request reprint Arsenite-induced nitric oxide generation is cell cycle-dependent and aberrant in NBS cells
    S S Yuan
    Department of Obstetrics and Gynecology, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan 807, Republic of China
    Toxicol In Vitro 17:139-43. 2003
    ..In summary, our study showed, for the first time, that arsenite-induced NO generation is cell-cycle- and NBS1-dependent...
  8. ncbi request reprint Altered p-JAK1 expression is associated with estrogen receptor status in breast infiltrating ductal carcinoma
    Y T Yeh
    Department of Medical Research and Department of Obstetrics and Gynecology, E Da Hospital, Kaohsiung, Taiwan, ROC
    Oncol Rep 17:35-9. 2007
    ..In summary, our results indicated that an altered p-JAK1 expression might be involved in the development of breast infiltrating ductal carcinoma in an ERalpha-related manner...