Stephanie A Studenski

..To expand the ability to assess physical frailty by developing a Clinical Global Impression of Change in Physical Frailty (CGIC-PF) instrument...

..To assess the ability of gait speed alone and a three-item lower extremity performance battery to predict 12-month rates of hospitalization, decline in health, and decline in function in primary care settings serving older adults...

..To evaluate whether CNS medication use in older adults was associated with a higher risk of future incident mobility limitation...

..The study objective was to evaluate whether multiple- or high-dose CNS medication use in older adults was associated with a higher risk of recurrent (>or=2) falls...

..Tests of walking during challenging conditions may uncover mobility difficulty that is not identified with usual gait testing...

..To determine the prevalence of self-reported napping and its association with subjective nighttime sleep duration and quality, as measured according to sleep-onset latency and sleep efficiency...

..To evaluate whether combined use of multiple central nervous system (CNS) medications over time is associated with cognitive change...

..To examine the association between poorer performance on concurrent walking and reaction time and recurrent falls...

..Understanding slowing gait could help improve function in older age. We examine whether the association between smaller PFAv and slower gait is explained by lower performance on numerous neuropsychological tests...

..To have health care professionals in nursing homes identify organizational-level and individual-level modifiable barriers to medication error reporting...

..To examine ethnic differences in fall rates and fall circumstances in older community-dwelling Caucasian and African-American women...

..To develop a consensus list of agreed-upon laboratory, pharmacy, and Minimum Data Set signals that a computer system can use in the nursing home to detect potential adverse drug reactions (ADRs)...

..Little is known about the impact of body mass index (BMI) on self-report and performance-based balance and mobility measures in older adults...

..To estimate the relationship between 1-year improvement in measures of health and physical function and 8-year survival...

..Design A cross-sectional secondary analysis of observational cohort data was conducted...

..To examine whether deficient B12 status or low serum B12 levels are associated with worse sensory and motor peripheral nerve function in older adults...

..The goal of this study was to analyze the association between the degree of SDD and the magnitude of an unexpected slip perturbation induced during gait...

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..To determine whether the cognitive function contribution to straight- and curved-path walking differs for older adults...

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..For mobility to be successfully integrated into clinical practice and health policy, an easily assessed marker that predicts subsequent health outcomes is required...

..To assess whether the Timed Up and Go (TUG) is superior to gait speed in predicting multiple geriatric outcomes...

..The aim of this study is to determine whether changes in B12 or Hcy levels are associated with longitudinal changes in peripheral nerve function and clinical neurological signs and symptoms...

..A task-oriented, motor sequence learning exercise intervention has been shown to reduce the energy cost of walking and improve gait speed, but whether the intervention also improves activity and participation has not been demonstrated...

..Extended walking tests have been examined as outcome predictors in medically ill populations but not in community-dwelling older adults...

..Gait speed is a strong predictor of incident walking disability. The objective was to determine if gait variability adds to the prediction of incident mobility disability independent of gait speed...

..Because walking may also be energy inefficient in people with decreased mobility, another approach is to reduce energy cost by improving timing and coordination (TC) of movement...

..To determine the association between fatigue and survival over 10 years in a population of older community-dwelling primary care patients...

..To describe the management of and satisfaction with laboratory testing, and desirability of laboratory health information technology in the nursing home setting...

..Although fatigue is a common and distressing symptom, a well-specified definition of fatigue is lacking. One of the least well-defined aspects of fatigue is its quality, which might reflect the underlying pathophysiology...

..This meeting and subsequent article were not meant to be a comprehensive review of frailty research; instead, they were and are meant to provide a more-targeted research agenda-setting process...

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..Fatigue is a common complaint among older adults, but the association of fatigue with subsequent function is not well known...

..The objective of this study was to conduct a systematic review of pharmacy and laboratory signals used by clinical event monitors to detect ADEs in hospitalized adults...

..To estimate the magnitude of small meaningful and substantial individual change in physical performance measures and evaluate their responsiveness...

..To examine the prevalence and correlates of non-opioid and opioid analgesic use and descriptively evaluate potential undertreatment in a sample of community-dwelling elders with symptomatic knee and/or hip osteoarthritis (OA)...

..The purpose of this study was to examine if the amelioration of stroke-related neuromuscular impairments, improved cardiovascular fitness, or better balance contributed to gains in distance walking...

..Before better reporting systems can be developed to reduce clinically significant medication errors, it is necessary to understand how current medication error reporting systems function...

..Striatal dopaminergic activity decreases with normal aging...

..It was found that even this brief exposure to geriatrics could have meaningful effects on student knowledge of and comfort with geriatrics...

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..Studies exploring the feasibility and benefits of a shared care model in the management of older patients with cancer are needed...

..We examined treatment effects on these outcomes in a randomized controlled trial (RCT) of exercise in subacute stroke survivors...

..Physical performance measures, such as gait speed, might help account for variability, allowing clinicians to make more individualized estimates...

..Specific patterns of gait variability may imply different underlying causes. Types of gait variability should be specified. Interventions may be targeted at specific types of gait variability...

..This study estimated clinically meaningful change in measures of gait variability using both distribution- and anchor-based approaches...

..It is not known whether these associations are also significant for longer-term adherence to moderate-intensity activities...

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..Our objective was to identify the spatial distribution of focal atrophy within mobility-related brain regions in relationship with quantitative gait characteristics...

..This study examined the association between gray matter volumes of regions related to motor control, gait, and balance and whether this association is independent of burden of white matter hyperintensities...

..National strategic initiatives are required to overcome barriers and to achieve clinical, research, and policy advances that will improve quality of life for older persons...

..The brain anatomical correlates of gait variability have not been studied in high-functioning community-dwelling older adults...

..The concept of the enriched environment currently employed in animal studies to promote physical activity, socialization, and problem solving should be explored in human studies...

..To investigate whether anemia predicts worsening white matter hyperintensities (WMHs) in older community-dwellers...

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..To examine the test-retest reliability and concurrent validity of variability of gait characteristics...

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..Next steps recommended include continuing clarification of terms and conceptual approaches, consideration of developing and improving measures, as well as developing new research directions...

..Assessment of selective olfactory deficits may be used as a simplified olfactory screening test in the evaluation of subjects with possible PD...

..We explored perceived advantages and disadvantages of video dance as a personal exercise option in postmenopausal women...

..Individuals with motor, sensory, and visual impairments are less mobile and less likely to fall than those individuals with motor deficits only or motor and sensory deficits...

..The purpose of this study was to compare disability and quality of life as measured by the Stroke Impact Scale (SIS) of stroke patients deemed recovered (Barthel Index > or =95) with 2 stroke-free populations of community-dwelling elderly...

..To examine the effect of exercise on depressive symptoms and the effect of baseline depressive symptoms on the benefits from exercise in stroke survivors who have completed acute rehabilitation...

..CD56(+) T cells are unique effectors capable of mediating TCR-independent immune cascades that could be harnessed to enhance protective immunity in the elderly...

..To evaluate the reliability and validity of the Spirituality Index of Well-Being (SIWB) Scale in a patient population...

..These stroke survivors have severely limited functional exercise capacity. Research and clinical practice in stroke rehabilitation should incorporate more comprehensive evaluation and treatment of endurance limitations...

..We investigated the association of depression with disability, apathy and resilience across the age range of late-life...

..A better understanding of immunological functioning in late life may help unlock novel ways to promote successful aging...

..062). Findings suggest that walking requires significant cognitive resources among older adults and slower-walking adults and weaker adults may require higher cognitive loading while walking...

..The purpose of this study was to develop, implement, and evaluate a handheld charge capture program for use by providers in the long-term care setting...

..Neuromuscular impairments poststroke contribute to diminished performance in the 6-minute walk test. Pulse and blood pressure pre- and posttesting can indicate cardiovascular stress...

..It is not clear whether greater fMRI activation indicates a strategy to compensate for underlying brain structural abnormalities while maintaining higher performance...

..Transient declines in gait speed and self-reported health are as common as persistent declines and affect mortality risk...

..Determine whether a rehabilitation program targeting functional motor recovery of persons with poststroke hemiparesis improved motor coordination...

..The purpose of this study was to examine the interaction of religion and spirituality with self-reported health status in a community-dwelling geriatric population...

..A prospective design was used to examine predictors of adherence to a physical activity intervention in older adults with compromised function...

..To describe several recruitment parameters derived from the Lifestyle Interventions and Independence for Elders pilot (LIFE-P) study for use in a full-scale trial of mobility disability prevention...