B L Strom

Summary

Affiliation: University of Pennsylvania
Country: USA

Publications

  1. ncbi Risk factors for clinically important adverse events after protamine administration following cardiopulmonary bypass
    S E Kimmel
    Center for Clinical Epidemiology and Biostatistics and Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia 19104 6021, USA
    J Am Coll Cardiol 32:1916-22. 1998
  2. ncbi When data conflict with practice: rethinking the use of prophylactic antibiotics before dental treatment
    B L Strom
    Leonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia, USA
    LDI Issue Brief 6:1-4. 2001
  3. ncbi Risk factors for infective endocarditis: oral hygiene and nondental exposures
    B L Strom
    Department of Biostatistics and Epidemiology and Center for Clinical Epidemiology and Biostatistics, Division of General Internal Medicine, University of Pennsylvania, Philadelpha 19104 6021, USA
    Circulation 102:2842-8. 2000
  4. ncbi Data validity issues in using claims data
    B L Strom
    Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104 6021, USA
    Pharmacoepidemiol Drug Saf 10:389-92. 2001
  5. ncbi Exposure to soy-based formula in infancy and endocrinological and reproductive outcomes in young adulthood
    B L Strom
    University of Pennsylvania, Center for Clinical Epidemiology and Biostatistics, 824 Blockley Hall, 423 Guardian Dr, Philadelphia, PA 19104 6021, USA
    JAMA 286:807-14. 2001
  6. ncbi Participants and refusers in a telephone interview about hormone replacement therapy were equally likely to be taking it
    Brian L Strom
    Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, 824 Blockley Hall, 423 Guardian Drive, Philadelphia, PA 19104 6021, USA
    J Clin Epidemiol 57:624-6. 2004
  7. ncbi Absence of cross-reactivity between sulfonamide antibiotics and sulfonamide nonantibiotics
    Brian L Strom
    Department of Biostatistics and Epidemiology, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 6021, USA
    N Engl J Med 349:1628-35. 2003
  8. ncbi Case-control study of postmenopausal hormone replacement therapy and endometrial cancer
    Brian L Strom
    Department of Medicine, School of Medicine, University of Pennsylvania, Philadelphia, 19104 6021, USA
    Am J Epidemiol 164:775-86. 2006
  9. ncbi Methodologic challenges to studying patient safety and comparative effectiveness
    Brian L Strom
    Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    Med Care 45:S13-5. 2007
  10. ncbi Absence of an effect of injectable and implantable progestin-only contraceptives on subsequent risk of breast cancer
    Brian L Strom
    Center for Clinical Epidemiology and Biostatistics and Department of Biostatistics and Epidemiology, 824 Blockley Hall, 423 Guardian Drive, University of Pennsylvania, Philadelphia, PA 19104 6021, USA
    Contraception 69:353-60. 2004

Research Grants

  1. Infectious Diseases Epidemiology Training Grant
    BRIAN STROM; Fiscal Year: 2007
  2. CLINICAL RESEARCH CURRICULUM
    BRIAN STROM; Fiscal Year: 2004
  3. CANCER CLINICAL EPIDEMIOLOGY TRAINING GRANT
    BRIAN STROM; Fiscal Year: 2007
  4. GERIATRIC CLINICAL EPIDEMIOLOGY TRAINING GRANT
    STEVEN HALBERT; Fiscal Year: 2007
  5. Clinical Pharmacoepidemiology Training Grant
    BRIAN STROM; Fiscal Year: 2007
  6. REPRODUCTIVE EPIDEMIOLOGY TRAINING GRANT
    BRIAN STROM; Fiscal Year: 2007
  7. Cardiology and Pulmonary Research Training Grant
    BRIAN STROM; Fiscal Year: 2007

Collaborators

Detail Information

Publications113 found, 100 shown here

  1. ncbi Risk factors for clinically important adverse events after protamine administration following cardiopulmonary bypass
    S E Kimmel
    Center for Clinical Epidemiology and Biostatistics and Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia 19104 6021, USA
    J Am Coll Cardiol 32:1916-22. 1998
    ..The purpose of this study was to determine risk factors for adverse events following protamine administration after cardiopulmonary bypass...
  2. ncbi When data conflict with practice: rethinking the use of prophylactic antibiotics before dental treatment
    B L Strom
    Leonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia, USA
    LDI Issue Brief 6:1-4. 2001
    ....
  3. ncbi Risk factors for infective endocarditis: oral hygiene and nondental exposures
    B L Strom
    Department of Biostatistics and Epidemiology and Center for Clinical Epidemiology and Biostatistics, Division of General Internal Medicine, University of Pennsylvania, Philadelpha 19104 6021, USA
    Circulation 102:2842-8. 2000
    ..The risks of infective endocarditis (IE) associated with various conditions and procedures are poorly defined...
  4. ncbi Data validity issues in using claims data
    B L Strom
    Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104 6021, USA
    Pharmacoepidemiol Drug Saf 10:389-92. 2001
    ..about which information cannot be obtained without accessing the patient...
  5. ncbi Exposure to soy-based formula in infancy and endocrinological and reproductive outcomes in young adulthood
    B L Strom
    University of Pennsylvania, Center for Clinical Epidemiology and Biostatistics, 824 Blockley Hall, 423 Guardian Dr, Philadelphia, PA 19104 6021, USA
    JAMA 286:807-14. 2001
    ..However, a paucity of data exists on the long-term effects of infant soy formulas...
  6. ncbi Participants and refusers in a telephone interview about hormone replacement therapy were equally likely to be taking it
    Brian L Strom
    Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, 824 Blockley Hall, 423 Guardian Drive, Philadelphia, PA 19104 6021, USA
    J Clin Epidemiol 57:624-6. 2004
    ..To address a major concern in pharmacoepidemiology studies related to whether the characteristics of responders are different from those who refuse to participate...
  7. ncbi Absence of cross-reactivity between sulfonamide antibiotics and sulfonamide nonantibiotics
    Brian L Strom
    Department of Biostatistics and Epidemiology, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 6021, USA
    N Engl J Med 349:1628-35. 2003
    ..The safety of sulfonamide nonantibiotics is unclear in patients with prior allergic reactions to sulfonamide antibiotics...
  8. ncbi Case-control study of postmenopausal hormone replacement therapy and endometrial cancer
    Brian L Strom
    Department of Medicine, School of Medicine, University of Pennsylvania, Philadelphia, 19104 6021, USA
    Am J Epidemiol 164:775-86. 2006
    ..Thus, if HRT is to be used in women with an intact uterus, this study confirms the benefit of adding progestins to the regimen...
  9. ncbi Methodologic challenges to studying patient safety and comparative effectiveness
    Brian L Strom
    Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    Med Care 45:S13-5. 2007
    ..This article provides a conceptual overview of these methodologic issues...
  10. ncbi Absence of an effect of injectable and implantable progestin-only contraceptives on subsequent risk of breast cancer
    Brian L Strom
    Center for Clinical Epidemiology and Biostatistics and Department of Biostatistics and Epidemiology, 824 Blockley Hall, 423 Guardian Drive, University of Pennsylvania, Philadelphia, PA 19104 6021, USA
    Contraception 69:353-60. 2004
    ..This study does not support an increased risk of breast cancer associated with the use of injectable or implantable progestin-only contraceptives in women aged 35 to 64...
  11. ncbi Potential for conflict of interest in the evaluation of suspected adverse drug reactions: a counterpoint
    Brian L Strom
    Department of Biostatistics and Epidemiology, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia 19104-6021, USA
    JAMA 292:2643-6. 2004
  12. ncbi An interview strategy was critical for obtaining valid information on the use of hormone replacement therapy
    Brian L Strom
    Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 6021, USA
    J Clin Epidemiol 57:1210-3. 2004
    ..We compared telephone reports of hormone replacement therapy (HRT) use to claims for drugs dispensed...
  13. ncbi How the US drug safety system should be changed
    Brian L Strom
    Department of Biostatistics and Epidemiology, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia 19104-6021, USA
    JAMA 295:2072-5. 2006
  14. ncbi Dental and cardiac risk factors for infective endocarditis. A population-based, case-control study
    B L Strom
    University of Pennsylvania School of Medicine, Veterans Affairs Medical Center, Philadelphia 19104 6021, USA
    Ann Intern Med 129:761-9. 1998
    ..Although antibiotic prophylaxis against infective endocarditis is recommended, the true risk factors for infective endocarditis are unclear...
  15. ncbi Pharmacogenetic modulation of combined hormone replacement therapy by progesterone-metabolism genotypes in postmenopausal breast cancer risk
    T R Rebbeck
    Center for Clinical Epidemiology and Biostatistics and Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA, USA
    Am J Epidemiol 166:1392-9. 2007
    ..Breast cancer risk in women who have used CHRT may be influenced by genetic factors involved in progestin metabolism...
  16. ncbi Flexible sigmoidoscopy training and its impact on colorectal cancer screening by primary care physicians
    J D Lewis
    Division of Gastroenterology, University of Pennsylvania, Philadelphia 19104, USA
    Arch Fam Med 9:420-5. 2000
    ..Colorectal cancer is an ideal disease for prevention with screening programs. Efforts to increase compliance with screening recommendations have included training primary care physicians to perform flexible sigmoidoscopy...
  17. ncbi Cigarette yield and the risk of myocardial infarction in smokers
    William H Sauer
    Department of Medicine, Cardiovascular Division, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Arch Intern Med 162:300-6. 2002
    ..001 for the trend). CONCLUSIONS: Smoking higher-yield cigarettes is associated with an increased risk of MI, and there is a dose-response relationship between total tar consumption per day and MI...
  18. ncbi Risk factors for delayed healing of neuropathic diabetic foot ulcers: a pooled analysis
    D J Margolis
    Department of Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 6021, USA
    Arch Dermatol 136:1531-5. 2000
    ..To estimate the effect of various risk factors on the probability that neuropathic diabetic foot ulcers will heal within 20 weeks of care...
  19. ncbi Effects of coronary stents on cardiovascular outcomes in broad-based clinical practice
    S E Kimmel
    University of Pennsylvania School of Medicine, Center for Clinical Epidemiology and Biostatistics, 717 Blockley Hall, 423 Guardian Dr, Philadelphia, PA 19104 6021, USA
    Arch Intern Med 160:2593-9. 2000
    ....
  20. ncbi An efficient design for verifying disease outcome status in large cohorts with rare exposures and low disease rates
    W B Bilker
    University of Pennsylvania, Department of Biostatistics and Epidemiology and Center for Clinical Epidemiology and Biostatistics, Blockley Hall, 423 Guardian Drive, Philadelphia, PA 19104 6021, USA
    Stat Med 18:3021-36. 1999
    ..We show that good efficiency can usually be achieved with a small subsample of unexposed cases. Published in 1999 by John Wiley & Sons, Ltd...
  21. ncbi Patients exposed to rofecoxib and celecoxib have different odds of nonfatal myocardial infarction
    Stephen E Kimmel
    University of Pennsylvania School of Medicine, Philadelphia 19104-6021, USA
    Ann Intern Med 142:157-64. 2005
    ..Cardiovascular effects among the COX-2 inhibitors seem different, but further studies, preferably randomized trials, are needed to fully understand the spectrum of effects of COX-2 inhibitors and potential differences among them...
  22. ncbi Immunosuppressant medications and mortality in inflammatory bowel disease
    James D Lewis
    Division of Gastroenterology, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    Am J Gastroenterol 103:1428-35; quiz 1436. 2008
    ..This study examined whether treatment of Crohn's disease (CD) and ulcerative colitis (UC) with immunosuppressant medications was associated with an increased risk of death in the era prior to antitumor necrosis factor (TNF) therapies...
  23. ncbi Preevent vaccination against smallpox: a survey of pediatric emergency health care providers
    Worth W Everett
    Department of Emergency Medicine, Hospital of the University of Pennsylvania, Centers for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, PA, USA
    Pediatr Infect Dis J 23:332-7. 2004
    ..A greater understanding of the knowledge, attitudes and beliefs of pediatric health care workers toward preevent smallpox vaccination will assist in the development of future bioterrorism preparedness programs...
  24. ncbi Statins and over-the-counter availability
    Brian L Strom
    University of Pennsylvania School of Medicine, Philadelphia, USA
    N Engl J Med 352:1403-5. 2005
  25. ncbi Effectiveness of platelet releasate for the treatment of diabetic neuropathic foot ulcers
    D J Margolis
    Department of Dermatology, University of Pennsylvania School of Medicine, Philadelphia 19104, USA
    Diabetes Care 24:483-8. 2001
    ....
  26. ncbi Practical aspects of sharing controls between case-control studies
    Greta R Bunin
    Center for Clinical Epidemiology and Biostatistics and Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Pharmacoepidemiol Drug Saf 14:523-30. 2005
    ..We discuss the practical advantages and challenges of sharing controls among two or more concurrently conducted case-control studies...
  27. ncbi Risk factors for nonadherence to warfarin: results from the IN-RANGE study
    Alec B Platt
    Department of Medicine, University of Pennsylvania School of Medicine, PA, USA
    Pharmacoepidemiol Drug Saf 17:853-60. 2008
    ..Warfarin is widely used to prevent stroke and venous thromboembolism despite its narrow therapeutic window. Warfarin nonadherence is a substantial problem, but risk factors have not been well elucidated...
  28. ncbi Reacting to antibiotic allergies
    Andrea J Apter
    Center for Clinical Epidemiology and Biostatistics, Center for Education and Research on Therapeutics, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    LDI Issue Brief 11:1-4. 2006
    ....
  29. ncbi Inflammatory bowel disease is not associated with an increased risk of lymphoma
    J D Lewis
    Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104 6021, USA
    Gastroenterology 121:1080-7. 2001
    ..Previous studies of the risk of lymphoma in inflammatory bowel disease patients have provided conflicting results. This study examines the risk of Hodgkin's and non-Hodgkin's lymphoma among patients with inflammatory bowel disease...
  30. ncbi Risk of venous thromboembolism from oral contraceptives containing gestodene and desogestrel versus levonorgestrel: a meta-analysis and formal sensitivity analysis
    S Hennessy
    Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    Contraception 64:125-33. 2001
    ..In the absence of a definitive answer, this apparent increased risk, together with its uncertainty and small magnitude and its important consequences, should be considered when selecting an OC for a given woman...
  31. ncbi Effect of adherence to newly initiated antiretroviral therapy on plasma viral load
    R Gross
    Division of Infectious Diseases, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104 6021, USA
    AIDS 15:2109-17. 2001
    ..To determine whether differences in adherence to newly initiated antiretroviral therapy exist between subjects who do and do not achieve undetectable plasma viral loads...
  32. ncbi Risk of acute first myocardial infarction and use of nicotine patches in a general population
    S E Kimmel
    Center for Clinical Epidmiology and Biostatistics and Department of Biostatistics and Epidmiology, University Pennsylvania School of Medicine, Philadelphia 19104 6021, USA
    J Am Coll Cardiol 37:1297-302. 2001
    ..To determine if nicotine patches, both as prescribed and used over-the-counter, increase the risk of first myocardial infarction (MI)...
  33. ncbi Prescriber adherence to pharmacokinetic monitoring service recommendations for aminoglycoside dosing and the risk of acute kidney injury
    S Hennessy
    Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Int J Clin Pharmacol Ther 49:536-44. 2011
    ..We aimed to examine the association between AKI and discordance in aminoglycoside dosing between physician orders and recommendations by a pharmacokinetic monitoring service...
  34. ncbi The risk of malignancy associated with psoriasis
    D Margolis
    Department of Dermatology, Biostatistics and Epidemiology, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, 423 Guardian Dr, Room 815, Blockley Hall, Philadelphia, PA 19104, USA
    Arch Dermatol 137:778-83. 2001
    ..To measure the incidence of cancer in patients with psoriasis, stratified by the severity of their disease...
  35. ncbi The epidemiology of the acute flank pain syndrome from suprofen
    B L Strom
    Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia 19104 6095
    Clin Pharmacol Ther 46:693-9. 1989
    ..These findings are consistent with the postulated mechanism for this unusual syndrome: acute diffuse crystallization of uric acid in renal tubules...
  36. ncbi Risk factors associated with the failure of a venous leg ulcer to heal
    D J Margolis
    Department of Dermatology, Center for Clinical Epidemiology, and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia 19104, USA
    Arch Dermatol 135:920-6. 1999
    ..Venous leg ulcers afflict a significant portion of the population. The most popular form of therapy for venous leg ulcers is a compression bandage (eg, Unna boot), a therapy that is frequently unsuccessful...
  37. ncbi Validation studies of the health improvement network (THIN) database for pharmacoepidemiology research
    James D Lewis
    Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 6021, USA
    Pharmacoepidemiol Drug Saf 16:393-401. 2007
    ..We sought to replicate in THIN well-established associations from the medical literature and to compare results from the GPRD practices to the non-GPRD practices within THIN...
  38. ncbi Hormone therapy and fatal breast cancer
    Sandra A Norman
    Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA 19104 6021, USA
    Pharmacoepidemiol Drug Saf 19:440-7. 2010
    ..Using a population-based case-control design, we estimated incidence rate ratios of fatal breast cancer in postmenopausal hormone therapy (HT) users compared to non-users by type, duration, and recency of HT use...
  39. ncbi Prevalence, risk factors, and outcomes for occult hepatitis B virus infection among HIV-infected patients
    Vincent Lo Re
    Division of Infectious Diseases, Department of Medicine, University of Pennsylvania School of Medicine, 423 Guardian Drive, Philadelphia, PA 19104, USA
    J Acquir Immune Defic Syndr 44:315-20. 2007
    ..The prevalence of occult HBV in HIV-infected patients remains controversial, and the risk factors and clinical significance are unknown...
  40. ncbi Can we predict daily adherence to warfarin?: Results from the International Normalized Ratio Adherence and Genetics (IN-RANGE) Study
    Alec B Platt
    MSCE, University of Pennsylvania School of Medicine, 707 Blockley Hall, 423 Guardian Dr, Philadelphia, PA 19104 6021, USA
    Chest 137:883-9. 2010
    ..Currently, no comprehensive screening tool exists to help providers assess the risk of nonadherence at the time of initiation of warfarin therapy...
  41. ncbi Estrogen sulfation genes, hormone replacement therapy, and endometrial cancer risk
    Timothy R Rebbeck
    Department of Biostatistics and Epidemiology and Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, 904 Blockley Hall, 423 Guardian Dr, Philadelphia, PA 19104 6021, USA
    J Natl Cancer Inst 98:1311-20. 2006
    ..To investigate the mechanism of this association, we evaluated whether risk of endometrial cancer was associated with the genotypes involved in steroid hormone metabolism and the duration of exogenous hormone use...
  42. ncbi Predictors of recall of over-the-counter and prescription non-steroidal anti-inflammatory drug exposure
    James D Lewis
    Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
    Pharmacoepidemiol Drug Saf 15:39-45. 2006
    ..Because of the difficulty in establishing a gold standard, data on accuracy of recall of over-the-counter (OTC) medication use are sparse...
  43. ncbi The role of academia and the research community in assisting the Food and Drug Administration to ensure U.S. drug safety
    Vincent Lo Re
    Department of Biostatistics and Epidemiology, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 6021, USA
    Pharmacoepidemiol Drug Saf 16:818-25. 2007
    ..We sought to examine ways that academia could expand its role in U.S. drug safety...
  44. ncbi Risk of bladder cancer among diabetic patients treated with pioglitazone: interim report of a longitudinal cohort study
    James D Lewis
    Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Diabetes Care 34:916-22. 2011
    ..This is an interim report of an ongoing cohort study examining the association between pioglitazone therapy and the risk of bladder cancer in patients with diabetes...
  45. ncbi Unintended effects of a computerized physician order entry nearly hard-stop alert to prevent a drug interaction: a randomized controlled trial
    Brian L Strom
    Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 6021, USA
    Arch Intern Med 170:1578-83. 2010
    ..The effectiveness of computerized physician order entry (CPOE) systems has been modest, largely because clinicians frequently override electronic alerts...
  46. ncbi Cardiovascular safety of ADHD medications: rationale for and design of an investigator-initiated observational study
    Sean Hennessy
    Center for Clinical Epidemiology and Biostatistics, and Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Pharmacoepidemiol Drug Saf 19:934-41. 2010
    ....
  47. ncbi A comparison of change in the 0-10 numeric rating scale to a pain relief scale and global medication performance scale in a short-term clinical trial of breakthrough pain intensity
    John T Farrar
    Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    Anesthesiology 112:1464-72. 2010
    ..The correlation of data from patients with breakthrough pain with a Pain Relief Scale and a different global outcome measures will extend our understanding of these measures...
  48. ncbi Diagnostic accuracy of CD4 cell count increase for virologic response after initiating highly active antiretroviral therapy
    Gregory P Bisson
    Department of Medicine, Division of Infectious Diseases, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania19104 6021, USA
    AIDS 20:1613-9. 2006
    ..To derive and internally validate a clinical prediction rule for virologic response based on CD4 cell count increase after initiation of HAART in a resource-limited setting...
  49. ncbi A retrospective case-control study of the use of hormone-related supplements and association with breast cancer
    Timothy R Rebbeck
    Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 6021, USA
    Int J Cancer 120:1523-8. 2007
    ..Additional confirmatory studies are required to determine whether black cohosh could be used to prevent breast cancer...
  50. ncbi Use of nonsteroidal antiinflammatory drugs and risk of breast cancer: the Case-Control Surveillance Study revisited
    Yuqing Zhang
    Clinical Epidemiology Research and Training Unit, School of Medicine, Boston University, Boston, MA 02118, USA
    Am J Epidemiol 162:165-70. 2005
    ..In conclusion, long-term regular use of NSAIDs was associated with decreased risk of breast cancer. The type of NSAID used or the hormone receptor status of the tumor did not modify the effect...
  51. ncbi Self-reported hepatitis B and C virus infections had low sensitivity among HIV-infected patients
    Vincent Lo Re
    Division of Infectious Diseases, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 6021, USA
    J Clin Epidemiol 60:294-9. 2007
    ..To determine the validity of self-reported hepatitis B virus (HBV) and hepatitis C virus (HCV) in HIV-infected injection drug users (IDUs) vs. nonIDUs...
  52. ncbi Antidiabetic action of bezafibrate in a large observational database
    James H Flory
    1Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    Diabetes Care 32:547-51. 2009
    ..The purpose of this study was to test the hypothesis that bezafibrate, an approved fibrate, can prevent or delay type 2 diabetes...
  53. ncbi Hormone-dependent effects of FGFR2 and MAP3K1 in breast cancer susceptibility in a population-based sample of post-menopausal African-American and European-American women
    Timothy R Rebbeck
    Abramson Cancer Center, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Carcinogenesis 30:269-74. 2009
    ..We further report that these genes confer their effects in HER2- tumors, interact with one another to confer breast cancer susceptibility in AA women and interact with hormone exposures in AA and EA women...
  54. ncbi Impact of raloxifene or tamoxifen use on endometrial cancer risk: a population-based case-control study
    Angela DeMichele
    Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA, USA
    J Clin Oncol 26:4151-9. 2008
    ....
  55. ncbi Patient reported receipt of medication instructions for warfarin is associated with reduced risk of serious bleeding events
    Joshua P Metlay
    Center for Clinical Epidemiology and Biostatistics, Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    J Gen Intern Med 23:1589-94. 2008
    ..Adverse drug events are an important cause of preventable hospitalizations...
  56. ncbi Association between serious ischemic cardiac outcomes and medications used to treat diabetes
    David J Margolis
    Department of Dermatology, University of Pennsylvania School of Medicine, PA 19104, USA
    Pharmacoepidemiol Drug Saf 17:753-9. 2008
    ..Data on cardiovascular outcomes among treated diabetics have been inconsistent. Our goal was to compare cardiovascular outcomes associated with different treatments for diabetes...
  57. ncbi Incidence of transaminitis among HIV-infected patients with occult hepatitis B
    Vincent Lo Re
    Division of Infectious Diseases, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 6021, USA
    J Clin Virol 43:32-6. 2008
    ..This information is needed to determine the importance of detecting and treating occult HBV in this population...
  58. ncbi Validity and comparison of two measures of days supply in Medicaid claims data
    Robert Gross
    Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 6021, USA
    Pharmacoepidemiol Drug Saf 17:1029-32. 2008
    ..The two measures should yield the same duration, but if not, the preferred method is unknown...
  59. ncbi Identifying and quantifying medication errors: evaluation of rapidly discontinued medication orders submitted to a computerized physician order entry system
    Ross Koppel
    Department of Sociology, University of Pennsylvania, Philadelphia, PA, USA
    J Am Med Inform Assoc 15:461-5. 2008
    ..This measure offers a rapid, constant, inexpensive, and objective method to identify medication orders with a high probability of error. It may also serve as a screening and teaching mechanism for physicians-in-training...
  60. ncbi The Ziprasidone Observational Study of Cardiac Outcomes (ZODIAC): design and baseline subject characteristics
    Brian L Strom
    Department of Biostatistics and Epidemiology, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 6021, USA
    J Clin Psychiatry 69:114-21. 2008
    ..Ziprasidone has been used to treat schizophrenia since 2000. It is unknown whether its modest QTc-prolonging effect increases cardiovascular event risk...
  61. ncbi Moderate and high affinity serotonin reuptake inhibitors increase the risk of upper gastrointestinal toxicity
    James D Lewis
    Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Pharmacoepidemiol Drug Saf 17:328-35. 2008
    ..This study examined the effect of medications that inhibit serotonin uptake on upper gastrointestinal toxicity...
  62. ncbi Cancer incidence in The Health Improvement Network
    Kevin Haynes
    Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 6021, USA
    Pharmacoepidemiol Drug Saf 18:730-6. 2009
    ..This study assessed whether the recorded incidence of cancer among patients in The Health Improvement Network (THIN) database is comparable to that expected in the UK based on national cancer registry data...
  63. ncbi Lack of effect modification between estrogen metabolism genotypes and combined hormone replacement therapy in postmenopausal breast cancer risk
    Timothy R Rebbeck
    Department of Biostatistics and Epidemiology, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104-6021, USA
    Cancer Epidemiol Biomarkers Prev 16:1318-20. 2007
  64. ncbi The risk of mortality in patients with psoriasis: results from a population-based study
    Joel M Gelfand
    MSCE, Department of Dermatology, University of Pennsylvania School of Medicine, 2 Maloney Bldg, 3600 Spruce St, Philadelphia, PA 19104, USA
    Arch Dermatol 143:1493-9. 2007
    ..To determine the risk of mortality in patients with psoriasis...
  65. ncbi Pairwise combinations of estrogen metabolism genotypes in postmenopausal breast cancer etiology
    Timothy R Rebbeck
    Department of Biostatistics and Epidemiology, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, 904 Blockley Hall, 423 Guardian Drive, Philadelphia, PA 19104 6021, USA
    Cancer Epidemiol Biomarkers Prev 16:444-50. 2007
    ....
  66. ncbi Increased risk of digoxin toxicity following hospitalization
    Kevin Haynes
    Program for the Reduction in Medication Errors, Department of Biostatistics and Epidemiology and School of Medicine, University of Pennsylvania, Philadelphia, PA 19104 6021, USA
    Pharmacoepidemiol Drug Saf 18:28-35. 2009
    ..The objective of the study was to identify health care system factors that affect the risk of digoxin toxicity for older adults on digoxin...
  67. ncbi The relationship between time since registration and measured incidence rates in the General Practice Research Database
    James D Lewis
    Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Pharmacoepidemiol Drug Saf 14:443-51. 2005
    ....
  68. ncbi Validity and completeness of the General Practice Research Database for studies of inflammatory bowel disease
    James D Lewis
    Center for Clinical Epidemiology and Biostatistics, Department of Medicine, University of Pennsylvania School of Medicine, 9th Floor Blockley Hall, 423 Guardian Drive, Philadelphia, PA 19104 6021, USA
    Pharmacoepidemiol Drug Saf 11:211-8. 2002
    ..The objective of this study was to evaluate the validity and completeness of the General Practice Research Database (GPRD) as a tool for research into inflammatory bowel disease epidemiology...
  69. ncbi Parenteral ketorolac and risk of myocardial infarction
    Stephen E Kimmel
    Center for Clinical Epidemiology and Biostatistics and Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    Pharmacoepidemiol Drug Saf 11:113-9. 2002
    ..To examine the effects of ketorolac, a non-aspirin non-steroidal anti-inflammatory drug (NANSAID) with antiplatelet properties, on the risk of in-hospital myocardial infarction (MI)...
  70. ncbi Combined effect of oral contraceptive use and hormone replacement therapy on breast cancer risk in postmenopausal women
    Sandra A Norman
    Center for Clinical Epidemiology and Biostatistics, Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA 19104 6021, USA
    Cancer Causes Control 14:933-43. 2003
    ..We examined breast cancer risk related to lifetime exposure to oral contraceptives (OCs) and hormone replacement therapy (HRT) in postmenopausal women...
  71. ncbi Longitudinal trends in fluoroquinolone resistance among Enterobacteriaceae isolates from inpatients and outpatients, 1989-2000: differences in the emergence and epidemiology of resistance across organisms
    Ebbing Lautenbach
    Division of Infectious Diseases, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 6021, USA
    Clin Infect Dis 38:655-62. 2004
    ..Efforts to elucidate the epidemiology of FQ resistance and identify targets for intervention must recognize and account for the variability of FQ resistance across organisms and clinical settings...
  72. ncbi Cardiac arrest and ventricular arrhythmia in patients taking antipsychotic drugs: cohort study using administrative data
    Sean Hennessy
    Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    BMJ 325:1070. 2002
    ..To examine the rates of cardiac arrest and ventricular arrhythmia in patients with treated schizophrenia and in non-schizophrenic controls...
  73. ncbi Smallpox vaccination: a national survey of emergency health care providers
    Worth W Everett
    Department of Emergency Medicine, Hospital of the University of Pennsylvania, Philadelphia 19104, USA
    Acad Emerg Med 10:606-11. 2003
    ..Although emergency health care providers are among the first targeted for vaccination, little is known about how these providers view the risks and benefits of SP vaccination...
  74. ncbi The effects of nonselective non-aspirin non-steroidal anti-inflammatory medications on the risk of nonfatal myocardial infarction and their interaction with aspirin
    Stephen E Kimmel
    Center for Clinical Epidemiology and Biostatistics, Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, 717 Blockley Hall, 423 Guardian Drive, Philadelphia, PA 19104 6021, USA
    J Am Coll Cardiol 43:985-90. 2004
    ....
  75. ncbi Comparative cardiac safety of low-dose thioridazine and low-dose haloperidol
    Sean Hennessy
    Center for Clinical Epidemiology and Biostatistics, Department of Biostatistics and Epidemiology, and Center for Education and Research in Therapeutics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Br J Clin Pharmacol 58:81-7. 2004
    ..To compare the rate of ventricular arrhythmia, sudden death and unexplained or unattended death among users of thioridazine and haloperidol...
  76. ncbi Hospitalization and mortality rates from peptic ulcer disease and GI bleeding in the 1990s: relationship to sales of nonsteroidal anti-inflammatory drugs and acid suppression medications
    James D Lewis
    Center for Clinical Epidemiology and Biostatistics, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia 19104-6021, USA
    Am J Gastroenterol 97:2540-9. 2002
    ..Changing rates of peptic ulcer disease morbidity and mortality were temporally related to increasing sales of antiulcerants but not to change in sales of NSAIDs...
  77. ncbi Clinically important changes in acute pain outcome measures: a validation study
    John T Farrar
    University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    J Pain Symptom Manage 25:406-11. 2003
    ..This provides support for the usefulness of these values in future clinical trials of pain therapy...
  78. ncbi Seasonal variation in flares of inflammatory bowel disease
    James D Lewis
    Center for Clinical Epidemiology and Biostatistics and Department of Medicine, University of Pennsylvania Centers for Education and Research on Therapeutics, Philadelphia, 19104 6021, USA
    Gastroenterology 126:665-73. 2004
    ..The purpose of this study was to determine whether relapse of inflammatory bowel disease follows a seasonal pattern either across a cohort of patients or within individual patients...
  79. ncbi Role of computerized physician order entry systems in facilitating medication errors
    Ross Koppel
    Department of Sociology, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia 19104 USA
    JAMA 293:1197-203. 2005
    ..Published studies report that CPOE reduces medication errors up to 81%. Few researchers, however, have focused on the existence or types of medication errors facilitated by CPOE...
  80. ncbi Descriptive analyses of the integrity of a US Medicaid claims database
    Sean Hennessy
    Center for Clinical Epidemiology, Department of Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Pharmacoepidemiol Drug Saf 12:103-11. 2003
    ..To examine the integrity of six Medicaid databases for use in pharmacoepidemiology research...
  81. ncbi Weight gain in the first week of life and overweight in adulthood: a cohort study of European American subjects fed infant formula
    Nicolas Stettler
    Division of Gastroenterology and Nutrition, The Children s Hospital of Philadelphia, 36th St and Civic Center Blvd, Philadelphia, PA 19104 4399, USA
    Circulation 111:1897-903. 2005
    ..Rapid infancy weight gain is associated with childhood obesity, whereas low infancy weight is associated with coronary heart disease. Our aim was to identify during which periods in infancy weight gain is associated with adult obesity...
  82. ncbi The incidence and prevalence of pressure ulcers among elderly patients in general medical practice
    David J Margolis
    Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Ann Epidemiol 12:321-5. 2002
    ..They are most likely to occur in those over 85 years of age. Preventative strategies within the general practice setting should concentrate on the oldest of the elderly...
  83. ncbi Comparative mortality associated with ziprasidone and olanzapine in real-world use among 18,154 patients with schizophrenia: The Ziprasidone Observational Study of Cardiac Outcomes (ZODIAC)
    Brian L Strom
    Department of Biostatistics and Epidemiology, the Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, 19104 6021, USA
    Am J Psychiatry 168:193-201. 2011
    ..The authors compared 1-year mortality rates associated with ziprasidone and olanzapine in real-world use...
  84. ncbi Agreement between patient self-report and a Veterans Affairs national pharmacy database for identifying recent exposures to antibiotics
    Joshua P Metlay
    Philadelphia Veterans Affairs Medical Center, Division of General Internal Medicine, Department of Medicine, Center for Clinical Epidemiology and Biostatistics, Univ of Pennsylvania, Philadelphia, PA, USA
    Pharmacoepidemiol Drug Saf 12:9-15. 2003
    ..The authors compared self-report with pharmacy dispensing data to determine the accuracy of self-reported antibiotic exposure...
  85. ncbi Epidemiological investigation of fluoroquinolone resistance in infections due to extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae
    E Lautenbach
    Division of Infectious Diseases, Department of Medicine, University of Pennsylvania Medical Center, Philadelphia, PA 19104 6021, USA
    Clin Infect Dis 33:1288-94. 2001
    ..83). The genotypes of fluoroquinolone-resistant ESBL-EK isolates were closely related. Efforts should be directed at modification of these risk factors to preserve the utility of fluoroquinolones in the treatment of ESBL-EK infections...
  86. ncbi Perioperative blood transfusion and postoperative mortality
    J L Carson
    Department of Medicine, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, New Brunswick 08903, USA
    JAMA 279:199-205. 1998
    ..The risks of blood transfusion have been studied extensively but the benefits and the hemoglobin concentration at which patients should receive a transfusion have not...
  87. ncbi Patient misunderstanding of dosing instructions
    N A Hanchak
    Hospital of the University of Pennsylvania, Philadelphia, USA
    J Gen Intern Med 11:325-8. 1996
    ..To promote optimal patient compliance, the outpatient prescription label should state the number of times a day a medication is to be taken...
  88. ncbi Predicting cutaneous hypersensitivity reactions to cotrimoxazole in HIV-infected individuals receiving primary Pneumocystis carinii pneumonia prophylaxis
    S Hennessy
    Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia 19104-6095, USA
    J Gen Intern Med 10:380-6. 1995
    ....
  89. ncbi What is the cost of nephrotoxicity associated with aminoglycosides?
    J M Eisenberg
    Department of Medicine, University of Pennsylvania, Philadelphia
    Ann Intern Med 107:900-9. 1987
    ..01). Additional consultations were $78 per patient. Therefore, the mean total additional cost of aminoglycoside-associated nephrotoxicity was $2501. The average additional cost per patient receiving aminoglycosides was $183...
  90. ncbi Detailed examination of fenfluramine-phentermine users with valve abnormalities identified in Fargo, North Dakota
    S E Kimmel
    Department of Medicine, Hospital of the University of Pennsylvania, and Center for Clinical Epidemiology, and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia 19104, USA
    Am J Cardiol 84:304-8. 1999
    ..Further study is needed to test these hypotheses...
  91. ncbi Primary care physicians' decisions to perform flexible sigmoidoscopy
    J D Lewis
    Division of Gastroenterology, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia 19104, USA
    J Gen Intern Med 14:297-302. 1999
    ..Self-perceived inefficiency in performing office-based flexible sigmoidoscopy deterred many of these physicians from providing this service for their patients...
  92. ncbi Prevalence and determinants of erectile dysfunction in hemodialysis patients
    S E Rosas
    Renal-Electrolyte and Hypertension Division, Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104-6021, USA
    Kidney Int 59:2259-66. 2001
    ..CONCLUSIONS: ED is extremely prevalent among HD patients. Increasing age, diabetes, and nonuse of ACEIs were associated with higher prevalence of ED. The high prevalence of ED was seen even among patients with good functional status...
  93. ncbi Treatment of osteoporosis: are physicians missing an opportunity?
    K B Freedman
    Department of Orthopaedic Surgery, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia 19104, USA
    J Bone Joint Surg Am 82:1063-70. 2000
    ..The purpose of this study was to evaluate the adequacy of diagnosis and treatment of osteoporosis in postmenopausal women following an acute fracture of the distal part of the radius...
  94. ncbi Effect of transdermal testosterone treatment on serum lipid and apolipoprotein levels in men more than 65 years of age
    P J Snyder
    Department of Medicine, University of Pennsylvania School of Medicine, 415 Curie Boulevard, Philadelphia, PA 19104, USA
    Am J Med 111:255-60. 2001
    ..The effect of testosterone treatment on cardiovascular events was unclear, because the number of events was small...
  95. ncbi The FDA and drug safety: a proposal for sweeping changes
    Curt D Furberg
    Department of Public Health Sciences, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    Arch Intern Med 166:1938-42. 2006
    ....
  96. ncbi Reproductive factors and risk of breast carcinoma in a study of white and African-American women
    Giske Ursin
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA
    Cancer 101:353-62. 2004
    ....
  97. ncbi Vitamin D receptor polymorphisms and breast cancer risk in a large population-based case-control study of Caucasian and African-American women
    Britton Trabert
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Fairview Ave N, Seattle, Washington 98109 1024, USA
    Breast Cancer Res 9:R84. 2007
    ..The involvement of vitamin D receptor (VDR), which is a key mediator in the vitamin D pathway, in breast cancer etiology has long been of interest...
  98. ncbi Relationship between established breast cancer risk factors and risk of seven different histologic types of invasive breast cancer
    Christopher I Li
    Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, M4 C308, P O Box 19024, Seattle, WA 98109 1024, USA
    Cancer Epidemiol Biomarkers Prev 15:946-54. 2006
    ....
  99. ncbi Lifetime recreational exercise activity and breast cancer risk among black women and white women
    Leslie Bernstein
    Department of Preventive Medicine, Keck School of Medicine, USC Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA 90033, USA
    J Natl Cancer Inst 97:1671-9. 2005
    ....
  100. ncbi Breast cancer risk estimates for relatives of white and African American women with breast cancer in the Women's Contraceptive and Reproductive Experiences Study
    Michael S Simon
    Division of Hematology and Oncology, Karmanos Cancer Institute at Wayne State University, Detroit, MI 48201, USA
    J Clin Oncol 24:2498-504. 2006
    ..The purpose of this report is to update breast cancer risk estimates associated with a family history of breast cancer for white and AA women...
  101. ncbi Lung cancer and regular use of aspirin and nonaspirin nonsteroidal anti-inflammatory drugs
    Judith P Kelly
    Slone Epidemiology Center of Boston University, Boston, MA 02215, USA
    Pharmacoepidemiol Drug Saf 17:322-7. 2008
    ..Our objective was to examine the association of regular use of ASA and NANSAIDs with lung cancer...

Research Grants8

  1. Infectious Diseases Epidemiology Training Grant
    BRIAN STROM; Fiscal Year: 2007
    ..All training faculty have primary appointments at the University of Pennsylvania. The primary areas of research include: clinical epidemiology, biostatistics, HIV, herpes simplex virus, economics, obstetrics, gynecology, and pediatrics. ..
  2. CLINICAL RESEARCH CURRICULUM
    BRIAN STROM; Fiscal Year: 2004
    ..I. and co-PI s in the three distinct aspects of Clinical Research targeted by this program represent particular features of this proposal. ..
  3. CANCER CLINICAL EPIDEMIOLOGY TRAINING GRANT
    BRIAN STROM; Fiscal Year: 2007
    ..g., clinical trials, case-control, cohort research, etc.), and the faculty members' commitment to collaborative research and training, combine to provide an ideal environment for the continuation of this training program. ..
  4. GERIATRIC CLINICAL EPIDEMIOLOGY TRAINING GRANT
    STEVEN HALBERT; Fiscal Year: 2007
    ..g., clinical trials, case control, cohort research, etc.), and the faculties' commitment to collaborative research. ..
  5. Clinical Pharmacoepidemiology Training Grant
    BRIAN STROM; Fiscal Year: 2007
    ....
  6. REPRODUCTIVE EPIDEMIOLOGY TRAINING GRANT
    BRIAN STROM; Fiscal Year: 2007
    ..g., clinical trials, case-control, cohort research, etc.), and the faculties' commitment to collaborative research and training, combine to provide an ideal environment for this proposed training program. ..
  7. Cardiology and Pulmonary Research Training Grant
    BRIAN STROM; Fiscal Year: 2007
    ..g., clinical trials, case-control, cohort research, etc.), and the faculties' commitment to collaborative research. ..