P L Strissel
Affiliation: University of Chicago
- DNA structural properties of AF9 are similar to MLL and could act as recombination hot spots resulting in MLL/AF9 translocations and leukemogenesisP L Strissel
University of Chicago Department of Medicine, Section of Hematology Oncology, Chicago, IL 60637 1470, USA
Hum Mol Genet 9:1671-9. 2000..We describe a DNA breakage and repair model for non-homologous recombination between MLL and its partner genes, particularly AF9...
- Cation-chromatin binding as shown by ion microscopy is essential for the structural integrity of chromosomesR Strick
Division of Biological Sciences, Department of Medicine, University of Chicago, IL 60637 1470, USA
J Cell Biol 155:899-910. 2001..Our study directly implicates Ca2+, Mg2+, Na+, and K+ in higher order chromosome structure through electrostatic neutralization and a functional interaction with nonhistone proteins...
- Scaffold attachment regions in centromere-associated DNAP L Strissel
Department of Hematology/Oncology, University of Chicago, Chicago, IL 60637, USA
Chromosoma 105:122-33. 1996..This clustering of SARs may be responsible in part for the tight chromatin packing associated with the primary constriction of the centromeric region...