J S Stringer

Summary

Affiliation: University of Alabama at Birmingham
Country: USA

Publications

  1. pmc Use of task-shifting to rapidly scale-up HIV treatment services: experiences from Lusaka, Zambia
    Mary B Morris
    Centre for Infectious Disease Research in Zambia Lusaka, Zambia
    BMC Health Serv Res 9:5. 2009
  2. pmc Universal nevirapine upon presentation in labor to prevent mother-to-child HIV transmission in high prevalence settings
    Jeffrey S A Stringer
    Schools of Medicine and Public Health, University of Alabama at Birmingham, Birmingham, Alabama, USA
    AIDS 18:939-43. 2004
  3. ncbi request reprint Nevirapine to prevent mother-to-child transmission of HIV-1 among women of unknown serostatus
    Jeffrey S A Stringer
    Schools of Medicine and Public Health, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Lancet 362:1850-3. 2003
  4. pmc Timing of the maternal drug dose and risk of perinatal HIV transmission in the setting of intrapartum and neonatal single-dose nevirapine
    Jeffrey S A Stringer
    Schools of Medicine and Public Health, University of Alabama at Birmingham, Birmingham, Alabama, USA
    AIDS 17:1659-65. 2003
  5. pmc Comparison of two strategies for administering nevirapine to prevent perinatal HIV transmission in high-prevalence, resource-poor settings
    Jeffrey S A Stringer
    Department of Obstetrics and Gynecology, Schools of Medicine and Public Health, University of Alabama at Birmingham, Alabama, USA
    J Acquir Immune Defic Syndr 32:506-13. 2003
  6. pmc Effect of nevirapine toxicity on choice of perinatal HIV prevention strategies
    Jeffrey S A Stringer
    Center for Research in Women s Health, University of Alabama at Birmingham, Birmingham, AL, USA
    Am J Public Health 92:365-6. 2002
  7. ncbi request reprint Rapid scale-up of antiretroviral therapy at primary care sites in Zambia: feasibility and early outcomes
    Jeffrey S A Stringer
    Schools of Medicine and Public Health, University of Alabama at Birmingham, Birmingham, USA
    JAMA 296:782-93. 2006
  8. ncbi request reprint Cost-effective use of nevirapine to prevent vertical HIV transmission in sub-Saharan Africa
    J S Stringer
    Department of Obstetrics and Gynecology, School of Medicine, University of Alabama at Birmingham, Birmingham, USA
    J Acquir Immune Defic Syndr 24:369-77. 2000
  9. ncbi request reprint Prevention of mother-to-child transmission of HIV in Thailand: physicians' attitudes on zidovudine use, pregnancy termination, and willingness to provide care
    J S Stringer
    Department of Obstetrics and Gynecology, University of Alabama at Birmingham, 35294 2170, USA
    J Acquir Immune Defic Syndr 21:217-22. 1999
  10. ncbi request reprint Rapid testing and zidovudine treatment to prevent vertical transmission of human immunodeficiency virus in unregistered parturients: a cost-effectiveness analysis
    J S Stringer
    Center for Research on Women s Health, Department of Obstetrics and Gynecology, University of Alabama at Birmingham, 35294, USA
    Obstet Gynecol 94:34-40. 1999

Research Grants

Collaborators

Detail Information

Publications53

  1. pmc Use of task-shifting to rapidly scale-up HIV treatment services: experiences from Lusaka, Zambia
    Mary B Morris
    Centre for Infectious Disease Research in Zambia Lusaka, Zambia
    BMC Health Serv Res 9:5. 2009
    ..While this approach has been successful, long-term solutions to the human resource crisis are also urgently needed to expand the number of providers and to slow staff migration out of the region...
  2. pmc Universal nevirapine upon presentation in labor to prevent mother-to-child HIV transmission in high prevalence settings
    Jeffrey S A Stringer
    Schools of Medicine and Public Health, University of Alabama at Birmingham, Birmingham, Alabama, USA
    AIDS 18:939-43. 2004
    ..To assess the uptake of and adherence to nevirapine to prevent mother-to-child HIV transmission among women of unknown HIV serostatus presenting in labor. We also assessed preliminary efficacy of the approach...
  3. ncbi request reprint Nevirapine to prevent mother-to-child transmission of HIV-1 among women of unknown serostatus
    Jeffrey S A Stringer
    Schools of Medicine and Public Health, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Lancet 362:1850-3. 2003
  4. pmc Timing of the maternal drug dose and risk of perinatal HIV transmission in the setting of intrapartum and neonatal single-dose nevirapine
    Jeffrey S A Stringer
    Schools of Medicine and Public Health, University of Alabama at Birmingham, Birmingham, Alabama, USA
    AIDS 17:1659-65. 2003
    ..Single-dose intrapartum and neonatal nevirapine (NVP) reduces perinatal HIV transmission and is in increasingly common use throughout the developing world...
  5. pmc Comparison of two strategies for administering nevirapine to prevent perinatal HIV transmission in high-prevalence, resource-poor settings
    Jeffrey S A Stringer
    Department of Obstetrics and Gynecology, Schools of Medicine and Public Health, University of Alabama at Birmingham, Alabama, USA
    J Acquir Immune Defic Syndr 32:506-13. 2003
    ....
  6. pmc Effect of nevirapine toxicity on choice of perinatal HIV prevention strategies
    Jeffrey S A Stringer
    Center for Research in Women s Health, University of Alabama at Birmingham, Birmingham, AL, USA
    Am J Public Health 92:365-6. 2002
    ..This study evaluated the validity of concerns about the toxicity of nevirapine (NVP) that have delayed its implementation as a perinatal HIV prevention strategy...
  7. ncbi request reprint Rapid scale-up of antiretroviral therapy at primary care sites in Zambia: feasibility and early outcomes
    Jeffrey S A Stringer
    Schools of Medicine and Public Health, University of Alabama at Birmingham, Birmingham, USA
    JAMA 296:782-93. 2006
    ..The Zambian Ministry of Health has scaled-up human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) care and treatment services at primary care clinics in Lusaka, using predominately nonphysician clinicians...
  8. ncbi request reprint Cost-effective use of nevirapine to prevent vertical HIV transmission in sub-Saharan Africa
    J S Stringer
    Department of Obstetrics and Gynecology, School of Medicine, University of Alabama at Birmingham, Birmingham, USA
    J Acquir Immune Defic Syndr 24:369-77. 2000
    ..To assess the cost-effectiveness of alternative strategies of nevirapine (NVP) administration to prevent vertical HIV transmission in sub-Saharan Africa...
  9. ncbi request reprint Prevention of mother-to-child transmission of HIV in Thailand: physicians' attitudes on zidovudine use, pregnancy termination, and willingness to provide care
    J S Stringer
    Department of Obstetrics and Gynecology, University of Alabama at Birmingham, 35294 2170, USA
    J Acquir Immune Defic Syndr 21:217-22. 1999
    ..Physician education concerning the value of HIV screening and antiretroviral therapy in HIV-infected pregnant women is needed urgently in Thailand...
  10. ncbi request reprint Rapid testing and zidovudine treatment to prevent vertical transmission of human immunodeficiency virus in unregistered parturients: a cost-effectiveness analysis
    J S Stringer
    Center for Research on Women s Health, Department of Obstetrics and Gynecology, University of Alabama at Birmingham, 35294, USA
    Obstet Gynecol 94:34-40. 1999
    ..To assess the potential effectiveness and costs of a program to prevent vertical transmission of human immunodeficiency virus (HIV) in parturients without prenatal care...
  11. ncbi request reprint Perceptions toward HIV, HIV screening, and the use of antiretroviral medications: a survey of maternity-based health care providers in Zambia
    Benjamin H Chi
    Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, Texas, USA
    Int J STD AIDS 15:685-90. 2004
    ..Among those never prescribing ART, most cited a lack of availability (83%). Our results highlight the need for further provider education, critical appraisal of the current system for HIV testing, and widespread distribution of ART...
  12. ncbi request reprint Evaluation of a new testing policy for human immunodeficiency virus to improve screening rates
    E M Stringer
    Department of Obstetrics and Gynecology, University of Alabama at Birmingham, Birmingham, Alabama 35249-7333, USA
    Obstet Gynecol 98:1104-8. 2001
    ..CONCLUSION: After implementation of a policy of routine HIV testing with active patient refusal, HIV testing rates increased among pregnant women in our large, urban obstetric clinic population...
  13. pmc Intrapartum tenofovir and emtricitabine reduces low-concentration drug resistance selected by single-dose nevirapine for perinatal HIV prevention
    Benjamin H Chi
    Centre for Infectious Disease Research in Zambia, Lusaka, Zambia
    AIDS Res Hum Retroviruses 25:1099-106. 2009
    ..The ability of single-dose TDF/FTC to protect against peripartum NVP-induced NNRTI resistance extends to minority populations. This efficacy is achieved without significant selection of TDF- or FTC-resistant viruses...
  14. ncbi request reprint Two decades of the safe motherhood initiative: time for another wooden spoon award?
    Alan T N Tita
    Center for Women s Reproductive Health and Maternal Fetal Medicine Division, Department of Obstetrics and Gynecology, University of Alabama at Birmingham, Birmingham, Alabama 35233, USA
    Obstet Gynecol 110:972-6. 2007
    ....
  15. pmc Do targeted HIV programs improve overall care for pregnant women?: Antenatal syphilis management in Zambia before and after implementation of prevention of mother-to-child HIV transmission programs
    Dara Potter
    Schools of Public Health and Medicine, University of Alabama at Birmingham, Birmingham, AL, USA
    J Acquir Immune Defic Syndr 47:79-85. 2008
    ..The implementation of disease-specific research or service programs may have an ancillary beneficial or harmful impact on routine clinical services...
  16. ncbi request reprint Single-dose tenofovir and emtricitabine for reduction of viral resistance to non-nucleoside reverse transcriptase inhibitor drugs in women given intrapartum nevirapine for perinatal HIV prevention: an open-label randomised trial
    Benjamin H Chi
    Centre for Infectious Disease Research in Zambia, Lusaka, Zambia
    Lancet 370:1698-705. 2007
    ..We aimed to investigate whether this complication would be reduced with a single peripartum intervention of tenofovir and emtricitabine...
  17. pmc Monitoring effectiveness of programmes to prevent mother-to-child HIV transmission in lower-income countries
    Elizabeth M Stringer
    Centre for Infectious Disease Research in Zambia, Lusaka, Zambia
    Bull World Health Organ 86:57-62. 2008
    ..Finally, we propose a novel community survey-based approach that could be implemented widely throughout the developing world with minor modifications to ongoing Demographic and Health Surveys...
  18. doi request reprint Addition of single-dose tenofovir and emtricitabine to intrapartum nevirapine to reduce perinatal HIV transmission
    Benjamin H Chi
    Centre for Infectious Disease Research in Zambia, Lusaka, Zambia
    J Acquir Immune Defic Syndr 48:220-3. 2008
    ..To determine the impact of adjuvant single-dose peripartum tenofovir/emtricitabine (TDF/FTC) on intrapartum/early postpartum HIV transmission...
  19. pmc Are treatments for cervical precancerous lesions in less-developed countries safe enough to promote scaling-up of cervical screening programs? A systematic review
    Eric Chamot
    Department of Epidemiology, School of Public Health, University of Alabama at Birmingham, Birmingham, AL, USA
    BMC Womens Health 10:11. 2010
    ....
  20. pmc A pilot study of food supplementation to improve adherence to antiretroviral therapy among food-insecure adults in Lusaka, Zambia
    Ronald A Cantrell
    Centre for Infectious Disease Research in Zambia, Plot 1275 Lubutu Road, Lusaka, Zambia
    J Acquir Immune Defic Syndr 49:190-5. 2008
    ..The provision of food supplementation to food-insecure patients initiating antiretroviral therapy (ART) may improve adherence to medications...
  21. ncbi request reprint Acute and chronic chorioamnionitis and the risk of perinatal human immunodeficiency virus-1 transmission
    Benjamin H Chi
    School of Medicine, University of Alabama, Birmingham, AL 35294 0024, USA
    Am J Obstet Gynecol 194:174-81. 2006
    ..This study was undertaken to examine the prevalence of acute and chronic chorioamnionitis among women infected with human immunodeficiency virus-1 (HIV-1) and to determine the relative contribution of each to perinatal HIV-1 transmission...
  22. pmc Declining HIV prevalence among young pregnant women in Lusaka, Zambia
    Elizabeth M Stringer
    Department of Obstetrics and Gynecology, University of Alabama, Birmingham, AL, United States of America
    Bull World Health Organ 86:697-702. 2008
    ..Recent reports suggest a possible decline in HIV sero-incidence in Zambia and some neighbouring countries. This study aimed to examine trends in HIV seroprevalence among pregnant and parturient women between 2002 and 2006...
  23. ncbi request reprint Cost and enrollment implications of targeting different source population for an HIV treatment program
    Benjamin H Chi
    Centre for Infectious Disease Research in Zambia, Lusaka, Zambia
    J Acquir Immune Defic Syndr 40:350-5. 2005
    ..Rapid scale-up of antiretroviral therapy (ART) is a worldwide priority, and ambitious targets for numbers on ART have been set. Antenatal clinics (ANCs) and tuberculosis (TB) clinics have been targeted as entry points into HIV care...
  24. pmc Adherence to first-line antiretroviral therapy affects non-virologic outcomes among patients on treatment for more than 12 months in Lusaka, Zambia
    Benjamin H Chi
    Centre for Infectious Disease Research in Zambia, Lusaka, Zambia
    Int J Epidemiol 38:746-56. 2009
    ..In resource-constrained settings, however, there are few validated measures. We examined the correlation between clinical outcomes and the medication possession ratio (MPR), a pharmacy-based measure of adherence...
  25. doi request reprint HIV disease progression by hormonal contraceptive method: secondary analysis of a randomized trial
    Elizabeth M Stringer
    Centre for Infectious Disease Research, Lusaka, Zambia
    AIDS 23:1377-82. 2009
    ..We hypothesized that women using depomedroxyprogesterone acetate (DMPA) contraception would have faster HIV disease progression than women using oral contraceptive pills (OCPs) and nonhormonal methods...
  26. pmc Early clinical and programmatic outcomes with tenofovir-based antiretroviral therapy in Zambia
    Benjamin H Chi
    Centre for Infectious Disease Research in Zambia, Lusaka, Zambia
    J Acquir Immune Defic Syndr 54:63-70. 2010
    ..In July 2007, amid some controversy over cost, Zambia was the first African country to introduce tenofovir (TDF) as a component of first-line antiretroviral therapy (ART) on a wide scale...
  27. pmc CD4+ response and subsequent risk of death among patients on antiretroviral therapy in Lusaka, Zambia
    Benjamin H Chi
    Centre for Infectious Disease Research in Zambia, Lusaka, Zambia
    J Acquir Immune Defic Syndr 52:125-31. 2009
    ..However, few have studied CD4+ response and its relationship to subsequent clinical outcomes in a programmatic setting...
  28. pmc Personal risk perception, HIV knowledge and risk avoidance behavior, and their relationships to actual HIV serostatus in an urban African obstetric population
    Elizabeth M Stringer
    Schools of Medicine and Public Health, University of Alabama at Birmingham, Birmingham, AL, USA
    J Acquir Immune Defic Syndr 35:60-6. 2004
    ..Before significant inroads can be made in decreasing the incidence of HIV infection among pregnant women, population-based strategies that involve men must be implemented...
  29. doi request reprint Predictors of rapid HIV testing acceptance and successful nevirapine administration in Zambian labor wards
    Karen M Megazzini
    School of Public Health, Department of Epidemiology, University of Alabama, Birmingham, AL, USA
    J Acquir Immune Defic Syndr 52:273-9. 2009
    ..Provision of HIV testing in labor provides an opportunity to reach susceptible women and infants...
  30. pmc A randomized trial of the intrauterine contraceptive device vs hormonal contraception in women who are infected with the human immunodeficiency virus
    Elizabeth M Stringer
    Centre for Infectious Disease Research in Zambia, Lusaka, Zambia
    Am J Obstet Gynecol 197:144.e1-8. 2007
    ..The purpose of this study was to determine whether the intrauterine contraceptive device (IUD) is effective and safe among women who are infected with the human immunodeficiency virus (HIV)...
  31. ncbi request reprint Detection of nevirapine in plasma using thin-layer chromatography
    Jeffrey G Dubuisson
    Division of Clinical Pharmacology, Department of Obstetrics and Gynecology, University of Alabama at Birmingham School of Medicine, USA
    J Acquir Immune Defic Syndr 35:155-7. 2004
    ..This report describes a fast, inexpensive thin-layer chromatography (TLC) method to detect the presence of NVP in human plasma...
  32. ncbi request reprint Effects of concentration and temperature on the stability of nevirapine in whole blood and serum
    Chantelle J Bennetto
    The University of Alabama at Birmingham, School of Medicine, Division of Clinical Pharmacology, 1530 3rd Ave South, VH 116, Birmingham, AL 35294 0019, USA
    Clin Chem 50:209-11. 2004
  33. ncbi request reprint Complete blood cell count as a surrogate CD4 cell marker for HIV monitoring in resource-limited settings
    Ray Y Chen
    Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA
    J Acquir Immune Defic Syndr 44:525-30. 2007
    ..We developed a more effective method based on a decision tree algorithm to classify subjects...
  34. ncbi request reprint Employment of off-duty staff: a strategy to meet the human resource needs for a large PMTCT program in Zambia
    Benjamin H Chi
    J Acquir Immune Defic Syndr 40:381-2. 2005
  35. ncbi request reprint Potential cost-effectiveness of maternal and infant antiretroviral interventions to prevent mother-to-child transmission during breast-feeding
    Courtney C Maclean
    Duke University School of Medicine, Durham, NC, USA
    J Acquir Immune Defic Syndr 38:570-7. 2005
    ..One-third of maternal-to-child HIV transmission occurs during breast-feeding (BF). Several trials are currently evaluating the efficacy of postpartum antiretrovirals to reduce BF transmission...
  36. ncbi request reprint Use of traditional medicine among pregnant women in Lusaka, Zambia
    Yolan Banda
    University of Zambia School of Medicine, Lusaka, Zambia
    J Altern Complement Med 13:123-7. 2007
    ..We studied the prevalence of and predictors for traditional medicine use among pregnant women seeking care in the Lusaka, Zambia public health system...
  37. pmc Influence of body mass index on pregnancy outcomes among HIV-infected and HIV-uninfected Zambian women
    Yolan Banda
    School of Medicine, University of Zambia, Lusaka, Zambia
    Trop Med Int Health 12:856-61. 2007
    ..To determine the influence of body mass index (BMI) on pregnancy outcomes of HIV-infected and HIV-uninfected Zambian women and to assess the possible role of BMI on mother-to-child transmission rate of HIV...
  38. ncbi request reprint Prevention of pediatric human immunodeficiency virus
    Catherine M Wilfert
    Elizabeth Glaser Pediatric AIDS Foundation, Duke University School of Medicine, 1917 Wildcat Creek Road, Chapel Hill, NC 27516, USA
    Semin Pediatr Infect Dis 15:190-8. 2004
  39. ncbi request reprint Rapid testing strategies for HIV-1 serodiagnosis in high-prevalence African settings
    Richard J Wright
    Tufts University School of Medicine Wright, Boston, Massachusetts, USA
    Am J Prev Med 27:42-8. 2004
    ..While recent commitment of resources from international donors is heartening, rational use of these resources for AIDS prevention and care will require a major scaling up of HIV diagnostic services in affected countries...
  40. ncbi request reprint Monitoring nevirapine-based programmes for prevention of mother-to-child transmission of HIV-1
    Jeffrey S A Stringer
    Lancet 362:667. 2003
  41. ncbi request reprint HIVCorps: using volunteers to rapidly expand HIV health services across Zambia
    Benjamin H Chi
    Centre for Infectious Disease Research in Zambia, Lusaka, Zambia
    Am J Trop Med Hyg 74:918-21. 2006
    ..Formal volunteer programs like HIVCorps should be developed alongside initiatives focused on deploying more specialized, experienced healthcare workers aboard...
  42. pmc Baseline renal insufficiency and risk of death among HIV-infected adults on antiretroviral therapy in Lusaka, Zambia
    Lloyd B Mulenga
    Centre for Infectious Disease Research, Zambia
    AIDS 22:1821-7. 2008
    ..To examine the association between baseline renal insufficiency and mortality among adults initiating antiretroviral therapy (ART) in an urban African setting...
  43. ncbi request reprint Individual-level predictors for HIV testing among antenatal attendees in Lusaka, Zambia
    Sara Thierman
    University of California School of Medicine, San Francisco, California, USA
    Am J Med Sci 332:13-7. 2006
    ..Because individual-level characteristics were only weakly predictive of HIV testing, future work should concentrate on community-level factors...
  44. ncbi request reprint Use of single-dose nevirapine for the prevention of mother-to-child transmission of HIV-1: does development of resistance matter?
    Michelle S McConnell
    Thailand US Centers for Disease Control and Prevention Collaboration, Nonthaburi, Thailand
    Am J Obstet Gynecol 197:S56-63. 2007
    ..Further research in the optimization of perinatal prevention regimens is needed...
  45. ncbi request reprint Clinical outcomes and CD4 cell response in children receiving antiretroviral therapy at primary health care facilities in Zambia
    Carolyn Bolton-Moore
    Centre for Infectious Disease Research in Zambia, Lusaka
    JAMA 298:1888-99. 2007
    ....
  46. ncbi request reprint Expanded services for the prevention of mother-to-child HIV transmission: field acceptability of a pilot program in Lusaka, Zambia
    Benjamin H Chi
    J Acquir Immune Defic Syndr 45:125-7. 2007
  47. pmc Early clinical and immune response to NNRTI-based antiretroviral therapy among women with prior exposure to single-dose nevirapine
    Benjamin H Chi
    Centre for Infectious Disease Research in Zambia, Zambia
    AIDS 21:957-64. 2007
    ....
  48. ncbi request reprint Field performance of a thin-layer chromatography assay for detection of nevirapine in umbilical cord blood
    Benjamin H Chi
    Centre for Infectious Disease Research in Zambia, Lusaka, Zambia
    HIV Clin Trials 7:263-9. 2006
    ..At present, the only validated method is high-performance liquid chromatography (HPLC), a technique poorly suited for most resource-constrained settings...
  49. doi request reprint Extended nevirapine prophylaxis to prevent HIV transmission
    Jeffrey S A Stringer
    University of Alabama at Birmingham, Centre for Infectious Disease Research in Zambia CIDRZ, Lusaka, Zambia
    Lancet 372:267-9. 2008
  50. pmc Simple adherence assessments to predict virologic failure among HIV-infected adults with discordant immunologic and clinical responses to antiretroviral therapy
    Jason D Goldman
    Centre for Infectious Disease Research in Zambia, Lusaka, Zambia
    AIDS Res Hum Retroviruses 24:1031-5. 2008
    ..Among patients with suspected treatment failure, a lower MPR was associated with higher rates of detectable viremia. However, the suboptimal sensitivity and specificity of MPR limit its utility as a sole predictor of virologic failure...
  51. pmc Management of cryotherapy-ineligible women in a "screen-and-treat" cervical cancer prevention program targeting HIV-infected women in Zambia: lessons from the field
    Krista S Pfaendler
    University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Gynecol Oncol 110:402-7. 2008
    ..We demonstrate the feasibility of implementing a referral and management system for cryotherapy-ineligible women in a "screen-and-treat" cervical cancer prevention program targeting HIV-infected women in Zambia...
  52. ncbi request reprint Cesarean delivery and risk of herpes simplex virus infection
    Dwight J Rouse
    JAMA 289:2208; author reply 2208-9. 2003
  53. pmc Integrating cervical cancer prevention in HIV/AIDS treatment and care programmes
    Mulindi H Mwanahamuntu
    Bull World Health Organ 86:D-E. 2008

Research Grants4

  1. Centre for Infectious Diseases Research in Zambia HIV/AIDS Clinical Trials Unit
    Jeffrey Stringer; Fiscal Year: 2007
    ..This CTU application is submitted in pursuit of this objective. ADMINISTRATIVE COMPONENT: ..
  2. UAB-ZAMBIA-HAITI HIV PREVENTION TRIALS UNIT
    Jeffrey Stringer; Fiscal Year: 2006
    ..Since other research and service funding supports these cohorts, the costs to maintain them prior to trials beginning are minimal. ..