Jeffrey R Strawn

Summary

Affiliation: University of Cincinnati
Country: USA

Publications

  1. doi request reprint Neurostructural abnormalities in pediatric anxiety disorders
    Jeffrey R Strawn
    Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati, College of Medicine, Cincinnati, OH, United States Cincinnati Children s Hospital Medical Center, Department of Pediatrics, Division of Child and Adolescent Psychiatry, Cincinnati, OH, United States Electronic address
    J Anxiety Disord 32:81-8. 2015
  2. doi request reprint A randomized, placebo-controlled study of duloxetine for the treatment of children and adolescents with generalized anxiety disorder
    Jeffrey R Strawn
    University of Cincinnati, College of Medicine, and Cincinnati Children s Hospital Medical Center, Division of Child and Adolescent Psychiatry, Cincinnati Electronic address
    J Am Acad Child Adolesc Psychiatry 54:283-93. 2015
  3. doi request reprint Cortical surface anatomy in pediatric patients with generalized anxiety disorder
    Jeffrey R Strawn
    Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati, College of Medicine, United States Department of Pediatrics, Division of Child and Adolescent Psychiatry, Cincinnati Children s Hospital Medical Center, Cincinnati, OH, United States Electronic address
    J Anxiety Disord 28:717-23. 2014
  4. pmc The treatment of generalized anxiety disorder with pregabalin, an atypical anxiolytic
    Jeffrey R Strawn
    Department of Psychiatry, University of Cincinnati, College of Medicine, Cincinnati, OH, USA
    Neuropsychiatr Dis Treat 3:237-43. 2007
  5. doi request reprint Neuroanatomic abnormalities in adolescents with generalized anxiety disorder: a voxel-based morphometry study
    Jeffrey R Strawn
    Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati, College of Medicine, Cincinnati, OH 45267, USA
    Depress Anxiety 30:842-8. 2013
  6. doi request reprint A pilot study of anterior cingulate cortex neurochemistry in adolescents with generalized anxiety disorder
    Jeffrey R Strawn
    Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati, College of Medicine, Cincinnati, Ohio, USA
    Neuropsychobiology 67:224-9. 2013
  7. doi request reprint Neurocircuitry of generalized anxiety disorder in adolescents: a pilot functional neuroimaging and functional connectivity study
    Jeffrey R Strawn
    Department of Psychiatry and Behavioral Neuroscience College of Medicine, University of Cincinnati, Cincinnati, Ohio 45267 0559, USA
    Depress Anxiety 29:939-47. 2012
  8. doi request reprint Psychopharmacologic treatment of children and adolescents with anxiety disorders
    Jeffrey R Strawn
    Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati, College of Medicine, Cincinnati, OH 45219, USA
    Child Adolesc Psychiatr Clin N Am 21:527-39. 2012
  9. doi request reprint Establishing the neurobiologic basis of treatment in children and adolescents with generalized anxiety disorder
    Jeffrey R Strawn
    Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati, College of Medicine, Cincinnati, Ohio 45267 0559, USA
    Depress Anxiety 29:328-39. 2012
  10. doi request reprint Low cerebrospinal fluid and plasma orexin-A (hypocretin-1) concentrations in combat-related posttraumatic stress disorder
    Jeffrey R Strawn
    Department of Psychiatry, University of Cincinnati, College of Medicine, Cincinnati, OH 45267 0559, USA
    Psychoneuroendocrinology 35:1001-7. 2010

Detail Information

Publications45

  1. doi request reprint Neurostructural abnormalities in pediatric anxiety disorders
    Jeffrey R Strawn
    Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati, College of Medicine, Cincinnati, OH, United States Cincinnati Children s Hospital Medical Center, Department of Pediatrics, Division of Child and Adolescent Psychiatry, Cincinnati, OH, United States Electronic address
    J Anxiety Disord 32:81-8. 2015
    ..These data suggest the presence of structural differences in regions previously implicated in the processing and regulation of fear in pediatric patients with anxiety disorders. ..
  2. doi request reprint A randomized, placebo-controlled study of duloxetine for the treatment of children and adolescents with generalized anxiety disorder
    Jeffrey R Strawn
    University of Cincinnati, College of Medicine, and Cincinnati Children s Hospital Medical Center, Division of Child and Adolescent Psychiatry, Cincinnati Electronic address
    J Am Acad Child Adolesc Psychiatry 54:283-93. 2015
    ..To evaluate the efficacy, safety, and tolerability of the selective serotonin norepinephrine inhibitor duloxetine in children and adolescents with generalized anxiety disorder (GAD)...
  3. doi request reprint Cortical surface anatomy in pediatric patients with generalized anxiety disorder
    Jeffrey R Strawn
    Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati, College of Medicine, United States Department of Pediatrics, Division of Child and Adolescent Psychiatry, Cincinnati Children s Hospital Medical Center, Cincinnati, OH, United States Electronic address
    J Anxiety Disord 28:717-23. 2014
    ....
  4. pmc The treatment of generalized anxiety disorder with pregabalin, an atypical anxiolytic
    Jeffrey R Strawn
    Department of Psychiatry, University of Cincinnati, College of Medicine, Cincinnati, OH, USA
    Neuropsychiatr Dis Treat 3:237-43. 2007
    ....
  5. doi request reprint Neuroanatomic abnormalities in adolescents with generalized anxiety disorder: a voxel-based morphometry study
    Jeffrey R Strawn
    Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati, College of Medicine, Cincinnati, OH 45267, USA
    Depress Anxiety 30:842-8. 2013
    ..Despite recent data implicating functional abnormalities in the neurocircuitry underlying emotional processing in pediatric anxiety disorders, little is known regarding neurostructural abnormalities within these systems...
  6. doi request reprint A pilot study of anterior cingulate cortex neurochemistry in adolescents with generalized anxiety disorder
    Jeffrey R Strawn
    Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati, College of Medicine, Cincinnati, Ohio, USA
    Neuropsychobiology 67:224-9. 2013
    ..This study used proton magnetic resonance spectroscopy (¹H MRS) to evaluate the neurochemistry of the anterior cingulate cortex (ACC) in adolescents with generalized anxiety disorder (GAD)...
  7. doi request reprint Neurocircuitry of generalized anxiety disorder in adolescents: a pilot functional neuroimaging and functional connectivity study
    Jeffrey R Strawn
    Department of Psychiatry and Behavioral Neuroscience College of Medicine, University of Cincinnati, Cincinnati, Ohio 45267 0559, USA
    Depress Anxiety 29:939-47. 2012
    ..We used standard fMRI and functional connectivity analyses to examine the functional neurocircuitry of GAD in adolescents...
  8. doi request reprint Psychopharmacologic treatment of children and adolescents with anxiety disorders
    Jeffrey R Strawn
    Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati, College of Medicine, Cincinnati, OH 45219, USA
    Child Adolesc Psychiatr Clin N Am 21:527-39. 2012
    ..In addition, some TCAs and SNRIs are effective. However, randomized controlled trials do not suggest efficacy for benzodiazepines or the atypical anxiolytic, buspirone, for children and adolescents with anxiety disorders...
  9. doi request reprint Establishing the neurobiologic basis of treatment in children and adolescents with generalized anxiety disorder
    Jeffrey R Strawn
    Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati, College of Medicine, Cincinnati, Ohio 45267 0559, USA
    Depress Anxiety 29:328-39. 2012
    ..These findings also raise the possibility that functional activity within the amygdala and VLPFC may be altered following successful treatment...
  10. doi request reprint Low cerebrospinal fluid and plasma orexin-A (hypocretin-1) concentrations in combat-related posttraumatic stress disorder
    Jeffrey R Strawn
    Department of Psychiatry, University of Cincinnati, College of Medicine, Cincinnati, OH 45267 0559, USA
    Psychoneuroendocrinology 35:1001-7. 2010
    ....
  11. doi request reprint Psychopharmacologic treatment of posttraumatic stress disorder in children and adolescents: a review
    Jeffrey R Strawn
    University of Cincinnati, Dept of Psychiatry, Cincinnati, OH 45267 0559, USA
    J Clin Psychiatry 71:932-41. 2010
    ..With these considerations in mind, we sought to summarize the current evidence for psychopharmacologic interventions in youth with PTSD...
  12. ncbi request reprint Olanzapine for the treatment of bipolar disorder in children and adolescents
    Jeffrey R Strawn
    Department of Psychiatry, University of Cincinnati, Box 670559, Cincinnati, OH 45267 0559, USA
    Expert Opin Pharmacother 9:467-74. 2008
    ....
  13. doi request reprint Post-traumatic stress symptoms and trauma exposure in youth with first episode bipolar disorder
    Jeffrey R Strawn
    Department of Psychiatry, University of Cincinnati, College of Medicine, Cincinnati, OH 45267 0559, USA
    Early Interv Psychiatry 4:169-73. 2010
    ..To examine the prevalence of trauma exposure as well as the rates and effects of post-traumatic stress disorder (PTSD) in adolescents with bipolar disorder following a first manic episode...
  14. ncbi request reprint Blood pressure and cerebrospinal fluid norepinephrine in combat-related posttraumatic stress disorder
    Jeffrey R Strawn
    Department of Psychiatry, College of Medicine, University of Cincinnati, Cincinnati, Ohio, USA
    Psychosom Med 66:757-9. 2004
    ..Central nervous system norepinephrine (NE) is normally involved in blood pressure regulation, but it is pathophysiologically elevated in posttraumatic stress disorder (PTSD)...
  15. ncbi request reprint Noradrenergic dysfunction and the psychopharmacology of posttraumatic stress disorder
    J R Strawn
    Department of Psychiatry, University of Cincinnati, College of Medicine, Cincinnati, Ohio 45267 0559, USA
    Depress Anxiety 25:260-71. 2008
    ..The utility of these anti-adrenergics in the clinical treatment of PTSD remains to be determined, though it is possible that they may prove to have primary roles in a disorder that is only modestly responsive to antidepressant treatment...
  16. ncbi request reprint Neuroleptic malignant syndrome
    Jeffrey R Strawn
    University of Cincinnati, Department of Psychiatry, College of Medicine, Box 670559, Cincinnati, OH 45267 0559, USA
    Am J Psychiatry 164:870-6. 2007
  17. ncbi request reprint Failure of glucagon-like peptide-1 to induce panic attacks or anxiety in patients with panic disorder
    J R Strawn
    Cincinnati Veterans Affairs Medical Center, Research Service, Cincinnati, OH 45220, USA
    J Psychiatr Res 42:787-9. 2008
    ..These data suggest that in humans, intraveneously administered GLP-1 does not appear to have anxiogenic or panicogenic properties, even in patients at highest risk for such reactions...
  18. doi request reprint Effects of trauma-related audiovisual stimulation on cerebrospinal fluid norepinephrine and corticotropin-releasing hormone concentrations in post-traumatic stress disorder
    Thomas D Geracioti
    Veterans Affairs Medical Center, Research Service, Cincinnati, OH, USA
    Psychoneuroendocrinology 33:416-24. 2008
    ....
  19. doi request reprint Effect of traumatic imagery on cerebrospinal fluid dopamine and serotonin metabolites in posttraumatic stress disorder
    Thomas D Geracioti
    Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
    J Psychiatr Res 47:995-8. 2013
    ....
  20. pmc Glutamatergic effects of divalproex in adolescents with mania: a proton magnetic resonance spectroscopy study
    Jeffrey R Strawn
    University of Cincinnati, College of Medicine, Cincinnati, OH 45267, USA
    J Am Acad Child Adolesc Psychiatry 51:642-51. 2012
    ....
  21. doi request reprint The association between salivary hormone levels and children's inpatient aggression: a pilot study
    Drew H Barzman
    Division of Child and Adolescent Psychiatry, Cincinnati Children s Hospital Medical Center, Cincinnati, OH, USA
    Psychiatr Q 84:475-84. 2013
    ....
  22. ncbi request reprint Elevated cerebrospinal fluid substance p concentrations in posttraumatic stress disorder and major depression
    Thomas D Geracioti
    Research Service, VA Medical Center, 3200 Vine St, Box 151, Cincinnati, OH 45220, USA
    Am J Psychiatry 163:637-43. 2006
    ..The authors also sought to determine if CNS substance P concentrations change on provocation of symptoms in PTSD patients...
  23. doi request reprint First-episode bipolar disorder is associated with erythrocyte membrane docosahexaenoic acid deficits: Dissociation from clinical response to lithium or quetiapine
    Robert K McNamara
    Department of Psychiatry and Behavioral Neuroscience, Division of Bipolar Disorders Research, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA Electronic address
    Psychiatry Res 230:447-53. 2015
    ..These data indicate that selective erythrocyte DHA deficits coincide with the initial onset of manic symptoms, and reductions in mood symptoms following treatment are not mediated by changes in fatty acid status. ..
  24. pmc Bipolar I disorder and major depressive disorder show similar brain activation during depression
    Michael A Cerullo
    Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH, USA
    Bipolar Disord 16:703-12. 2014
    ..These shared brain regions might be expected to exhibit similar activation in individuals with MDD and BP-I during functional magnetic resonance imaging (fMRI)...
  25. doi request reprint Neurostructural impact of co-occurring anxiety in pediatric patients with major depressive disorder: a voxel-based morphometry study
    Anna M Wehry
    Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati, College of Medicine, 260 Stetson Street, Suite 3200, ML 0559, Cincinnati, OH 45267 0559, USA Electronic address
    J Affect Disord 171:54-9. 2015
    ..Despite this, little is known regarding the neurostructural differences between anxiety disorders and major depressive disorder (MDD). Moreover, the neurophysiologic impact of the presence of anxiety in adolescents with MDD is unknown...
  26. pmc Antipsychotic polypharmacy in children and adolescents at discharge from psychiatric hospitalization
    Shannon N Saldana
    Department of Pharmacy, Intermountain Primary Children s Hospital, Salt Lake City, Utah Division of Pharmacy, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio
    Pharmacotherapy 34:836-44. 2014
    ..Thus, we sought to examine the demographic and clinical characteristics of psychiatrically hospitalized children and adolescents who were prescribed antipsychotic polypharmacy and to identify predictors of this prescribing pattern...
  27. ncbi request reprint Pharmacologic treatment considerations in co-occurring bipolar and anxiety disorders
    Paul E Keck
    Psychopharmacology Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, OH 45267 0559, USA
    J Clin Psychiatry 67:8-15. 2006
    ..Anxiety disorders are among the most commonly co-occurring psychiatric syndromes with bipolar disorder. The presence of co-occurring anxiety disorders has important prognostic and treatment implications...
  28. doi request reprint Low cerebrospinal fluid neuropeptide Y concentrations in posttraumatic stress disorder
    Renu Sah
    Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio 45237, USA
    Biol Psychiatry 66:705-7. 2009
    ..Posttraumatic stress disorder (PTSD) is a stress-related anxiety disorder. We hypothesized that central nervous system NPY is dysregulated in PTSD and sought to redress the absence of central NPY data in the disorder...
  29. doi request reprint Atypical neuroleptic malignant syndrome: diagnostic controversies and considerations
    Lara S Picard
    Division of Pharmacy Practice and Administrative Sciences, College of Pharmacy, University of Cincinnati, Cincinnati, OH, USA
    Pharmacotherapy 28:530-5. 2008
    ..In patients receiving any antipsychotic, clinicians should carefully evaluate any features of NMS and should not prematurely exclude a diagnosis of NMS in cases where severe rigidity or hyperthermia is not initially apparent...
  30. doi request reprint Sexual abuse is associated with obese children and adolescents admitted for psychiatric hospitalization
    Brooks R Keeshin
    Mayerson Center for Safe and Healthy Children, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45219, USA
    J Pediatr 163:154-9.e1. 2013
    ..To determine the relationship between a history of child abuse and obesity among children admitted for psychiatric hospitalization...
  31. pmc Interventions for youth at high risk for bipolar disorder and schizophrenia
    Robert K McNamara
    Division of Bipolar Disorders Research, Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA
    Child Adolesc Psychiatr Clin N Am 21:739-51. 2012
    ..A clinical vignette describing antidepressant-induced manic symptoms in an adolescent with a family history of bipolar disorder is provided...
  32. pmc The co-occurrence of cigarette smoking and bipolar disorder: phenomenology and treatment considerations
    Jaimee L Heffner
    Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine Cincinnati Veterans Affairs Medical Center, Cincinnati, OH 45237, USA
    Bipolar Disord 13:439-53. 2011
    ..The goal of this review is to synthesize the literature on the epidemiology, consequences, and treatment of smoking and nicotine dependence among individuals with BD and to delineate a future research agenda...
  33. ncbi request reprint Pituitary-thyroid state correlates with central dopaminergic and serotonergic activity in healthy humans
    J R Strawn
    Department of Psychiatry, University of Cincinnati, College of Medicine, Cincinnati, Ohio, USA
    Neuropsychobiology 49:84-7. 2004
    ..These results indicate that CNS monoamine-thyroid interactions are of physiological significance in the normal, euthyroid human...
  34. ncbi request reprint Intra- and inter-individual relationships between central and peripheral serotonergic activity in humans: a serial cerebrospinal fluid sampling study
    J R Strawn
    Department of Psychiatry, Cincinnati VAMC and University of Cincinnati College of Medicine, Cincinnati, OH, USA
    Life Sci 71:1219-25. 2002
    ..However, plasma 5-HIAA concentrations provide no significant information about absolute levels of the serotonin metabolite in the CSF...
  35. pmc Efficacy and tolerability of antidepressants in pediatric anxiety disorders: a systematic review and meta-analysis
    Jeffrey R Strawn
    Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati, College of Medicine, Cincinnati, Ohio Department of Psychiatry, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio
    Depress Anxiety 32:149-57. 2015
    ..However, there are no recent, systematic analyses of the efficacy, safety, or tolerability of these medications in pediatric anxiety disorders...
  36. doi request reprint Cortisol awakening response in adolescents with acute sexual abuse related posttraumatic stress disorder
    Brooks R Keeshin
    Mayerson Center for Safe and Healthy Children, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio Division of Child and Adolescent Psychiatry, Department of Pediatrics, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio
    Depress Anxiety 31:107-14. 2014
    ..Therefore, in this pilot study, we utilized non-stressed home saliva collection three times a day for three days to assess the levels, diurnal variation and awakening response of cortisol in recently sexually abused adolescent girls...
  37. doi request reprint Assessment and treatment of anxiety disorders in children and adolescents
    Anna M Wehry
    College of Medicine, Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati, Cincinnati, OH, 45219, USA
    Curr Psychiatry Rep 17:52. 2015
    ....
  38. doi request reprint Psychological and pharmacologic treatment of youth with posttraumatic stress disorder: an evidence-based review
    Brooks R Keeshin
    Department of Pediatrics, Mayerson Center for Safe and Healthy Children, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA Division of Child and Adolescent Psychiatry, Department of Pediatrics, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45219, USA Electronic address
    Child Adolesc Psychiatr Clin N Am 23:399-411, x. 2014
    ..The extant treatment studies in pediatric patients with PTSD and consensus recommendations suggest that treatment should be based on the individual child's most distressing and functionally impairing symptoms. ..
  39. doi request reprint Physiologic changes associated with violence and abuse exposure: an examination of related medical conditions
    Brooks R Keeshin
    Mayerson Center for Safe and Healthy Children, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229, USA
    Trauma Violence Abuse 13:41-56. 2012
    ..Importantly, additional work is needed to advance our emerging understanding of the biological mechanisms connecting exposure to violence and abuse and negative health outcomes...
  40. ncbi request reprint In-use stability of monoamine metabolites in human cerebrospinal fluid
    J R Strawn
    Cincinnati Veterans Affairs Medical Center, Department of Psychiatry, OH 45220 2213, USA
    J Chromatogr B Biomed Sci Appl 760:301-6. 2001
    ..These results demonstrate the in-use stability of 5-HIAA and HVA in human CSF under commonly-encountered laboratory conditions...
  41. doi request reprint Hyperthermia and rhabdomyolysis in an adolescent treated with topiramate and olanzapine
    Jeffrey R Strawn
    J Child Adolesc Psychopharmacol 18:116-8. 2008
  42. ncbi request reprint Early bicarbonate loading and dantroline for ziprasidone/haloperidol-induced neuroleptic malignant syndrome
    Jeffrey R Strawn
    J Clin Psychiatry 67:677. 2006
  43. ncbi request reprint Comment: Prazosin treatment of nightmares related to posttraumatic stress disorder
    Jeffrey R Strawn
    Ann Pharmacother 41:1917-8. 2007
  44. ncbi request reprint Aripiprazole and the neuroleptic malignant syndrome
    Jeffrey R Strawn
    Schizophr Res 85:298-9. 2006
  45. ncbi request reprint Successful treatment of catatonia with aripiprazole in an adolescent with psychosis
    Jeffrey R Strawn
    J Child Adolesc Psychopharmacol 17:733-5. 2007