R G Strauss

Summary

Affiliation: University of Iowa
Country: USA

Publications

  1. pmc Anaemia of prematurity: pathophysiology and treatment
    Ronald G Strauss
    University of Iowa College of Medicine, 200 Hawkins Drive, C250 GH, Iowa City, IA 52242 1009, United States
    Blood Rev 24:221-5. 2010
  2. doi request reprint Role of granulocyte/neutrophil transfusions for haematology/oncology patients in the modern era
    Ronald G Strauss
    Department of Pathology and Pediatrics, University of Iowa College of Medicine, Iowa City, USA
    Br J Haematol 158:299-306. 2012
  3. ncbi request reprint Alloimmunization in preterm infants after repeated transfusions of WBC-reduced RBCs from the same donor
    R G Strauss
    Department of Pathology, University of Iowa College of Medicine, Iowa City 52242 1182, USA
    Transfusion 40:1463-8. 2000
  4. pmc How I transfuse red blood cells and platelets to infants with the anemia and thrombocytopenia of prematurity
    Ronald G Strauss
    Department of Pathology, University of Iowa College of Medicine, Iowa City, IA 52242, USA
    Transfusion 48:209-17. 2008
  5. ncbi request reprint Rationale for medical director acceptance or rejection of allogeneic plateletpheresis donors with underlying medical disorders
    Ronald G Strauss
    University of Iowa DeGowin Blood Center, University of Iowa Hospitals, University of Iowa College of Medicine, Iowa City, IA 52242 1182, USA
    J Clin Apher 17:111-7. 2002
  6. pmc Commentary: is it safe to limit allogeneic red blood cell transfusions to neonates?
    Ronald G Strauss
    Department of Pathology, University of Iowa College of Medicine, Iowa City, Iowa, USA
    Neonatology 93:217-22. 2008
  7. ncbi request reprint Circulating RBC volume, measured with biotinylated RBCs, is superior to the Hct to document the hematologic effects of delayed versus immediate umbilical cord clamping in preterm neonates
    Ronald G Strauss
    Department of Pathology, University of Iowa Roy J and Lucille A Carver College of Medicine, University of Iowa Hospitals and Clinics, Iowa City, Iowa 52242, USA
    Transfusion 43:1168-72. 2003
  8. ncbi request reprint Safety of donating multiple products in a single apheresis collection: are we expecting too much?
    Ronald G Strauss
    Department of Pathology, University of Iowa College of Medicine, Iowa City, Iowa, USA
    J Clin Apher 18:135-40. 2003
  9. ncbi request reprint Elmer L. DeGowin, MD: blood transfusions in war and peace
    Ronald G Strauss
    DeGowin Blood Center, University of Iowa Hospital, College of Medicine, University of Iowa, Iowa City, IA 52242 1009, USA
    Transfus Med Rev 20:165-8. 2006
  10. ncbi request reprint Controversies in the management of the anemia of prematurity using single-donor red blood cell transfusions and/or recombinant human erythropoietin
    Ronald G Strauss
    Department of Pathology, DeGowin Blood Center, University of Iowa College of Medicine, Iowa City, 52242, USA
    Transfus Med Rev 20:34-44. 2006

Research Grants

Collaborators

Detail Information

Publications45

  1. pmc Anaemia of prematurity: pathophysiology and treatment
    Ronald G Strauss
    University of Iowa College of Medicine, 200 Hawkins Drive, C250 GH, Iowa City, IA 52242 1009, United States
    Blood Rev 24:221-5. 2010
    ..RBC transfusions are the mainstay of therapy with recombinant human erythropoietin largely unused because it fails to substantially diminish RBC transfusion needs--despite exerting substantial erythropoietic effects on neonatal marrow...
  2. doi request reprint Role of granulocyte/neutrophil transfusions for haematology/oncology patients in the modern era
    Ronald G Strauss
    Department of Pathology and Pediatrics, University of Iowa College of Medicine, Iowa City, USA
    Br J Haematol 158:299-306. 2012
    ..Accordingly, they cannot be recommended for standard therapy at this time...
  3. ncbi request reprint Alloimmunization in preterm infants after repeated transfusions of WBC-reduced RBCs from the same donor
    R G Strauss
    Department of Pathology, University of Iowa College of Medicine, Iowa City 52242 1182, USA
    Transfusion 40:1463-8. 2000
    ....
  4. pmc How I transfuse red blood cells and platelets to infants with the anemia and thrombocytopenia of prematurity
    Ronald G Strauss
    Department of Pathology, University of Iowa College of Medicine, Iowa City, IA 52242, USA
    Transfusion 48:209-17. 2008
  5. ncbi request reprint Rationale for medical director acceptance or rejection of allogeneic plateletpheresis donors with underlying medical disorders
    Ronald G Strauss
    University of Iowa DeGowin Blood Center, University of Iowa Hospitals, University of Iowa College of Medicine, Iowa City, IA 52242 1182, USA
    J Clin Apher 17:111-7. 2002
    ....
  6. pmc Commentary: is it safe to limit allogeneic red blood cell transfusions to neonates?
    Ronald G Strauss
    Department of Pathology, University of Iowa College of Medicine, Iowa City, Iowa, USA
    Neonatology 93:217-22. 2008
    ..Until definitive data are reported by additional studies, it seems prudent not to severely restrict/limit allogeneic RBC transfusions to neonates - except in approved investigational settings...
  7. ncbi request reprint Circulating RBC volume, measured with biotinylated RBCs, is superior to the Hct to document the hematologic effects of delayed versus immediate umbilical cord clamping in preterm neonates
    Ronald G Strauss
    Department of Pathology, University of Iowa Roy J and Lucille A Carver College of Medicine, University of Iowa Hospitals and Clinics, Iowa City, Iowa 52242, USA
    Transfusion 43:1168-72. 2003
    ..e., a fall in plasma volume concentrates RBCs to increase Hct; a rise in plasma volume dilutes RBCs to decrease Hct)...
  8. ncbi request reprint Safety of donating multiple products in a single apheresis collection: are we expecting too much?
    Ronald G Strauss
    Department of Pathology, University of Iowa College of Medicine, Iowa City, Iowa, USA
    J Clin Apher 18:135-40. 2003
    ....
  9. ncbi request reprint Elmer L. DeGowin, MD: blood transfusions in war and peace
    Ronald G Strauss
    DeGowin Blood Center, University of Iowa Hospital, College of Medicine, University of Iowa, Iowa City, IA 52242 1009, USA
    Transfus Med Rev 20:165-8. 2006
    ..The legacy of Dr. DeGowin to provide exemplary service, teaching, and research has been sustained by the physicians and staff of the Elmer L. DeGowin Memorial Blood Center (University of Iowa Hospitals and Clinics, Iowa City, Ia)...
  10. ncbi request reprint Controversies in the management of the anemia of prematurity using single-donor red blood cell transfusions and/or recombinant human erythropoietin
    Ronald G Strauss
    Department of Pathology, DeGowin Blood Center, University of Iowa College of Medicine, Iowa City, 52242, USA
    Transfus Med Rev 20:34-44. 2006
    ..Clearly, rHuEPO has efficacy in stimulating erythropoiesis in preterm infants, but success in the elimination or marked reduction in the need for RBC transfusions has not been definitively demonstrated...
  11. pmc A randomized clinical trial comparing immediate versus delayed clamping of the umbilical cord in preterm infants: short-term clinical and laboratory endpoints
    Ronald G Strauss
    Department of Pathology and Pediatrics, University of Iowa College of Medicine, Iowa City, Iowa 52242, USA
    Transfusion 48:658-65. 2008
    ..This study compared hematologic and clinical effects of delayed versus immediate cord clamping...
  12. ncbi request reprint A randomized, blinded trial comparing the hemostatic effects of pentastarch versus hetastarch
    Ronald G Strauss
    University of Iowa DeGowin Blood Center and the Department of Pathology, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA
    Transfusion 42:27-36. 2002
    ..Solutions of HES are widely accepted internationally but are used only modestly in the United States, largely because of concerns over hemostasis...
  13. doi request reprint One pathway to academic success: autobiography of Dr Ronald G. Strauss
    Ronald G Strauss
    University of Iowa College of Medicine, Associate Medical Director, LifeSource Institute for Transfusion Medicine, Chicago, IL, USA
    Transfus Med Rev 26:85-9. 2012
    ..Without such an opportunity, success in research will be elusive...
  14. ncbi request reprint Leukocyte-reduction to prevent transfusion-transmitted cytomegalovirus infections
    R G Strauss
    UI DeGowin Blood Center, University of Iowa, College of Medicine, Iowa City 52242 1182, USA
    Pediatr Transplant 3:19-22. 1999
    ....
  15. ncbi request reprint Blood banking issues pertaining to neonatal red blood cell transfusions
    R G Strauss
    University of Iowa College of Medicine, Iowa City 52242 1182, USA
    Transfus Sci 21:7-19. 1999
    ....
  16. pmc 2008 Emily Cooley Memorial Lecture: lessons learned from pediatric transfusion medicine clinical trials . . . a little child shall lead them
    Ronald G Strauss
    Department of Pathology, University of Iowa Hospitals and Clinics, Iowa City, Iowa 52242 1009, USA
    Transfusion 49:1996-2004. 2009
    ....
  17. pmc Is there a role for autologous/placental red blood cell transfusions in the anemia of prematurity?
    Ronald G Strauss
    Department of Pathology, University of Iowa College of Medicine, Iowa City, IA 52242, USA
    Transfus Med Rev 24:125-9. 2010
    ....
  18. ncbi request reprint Pretransfusion trigger platelet counts and dose for prophylactic platelet transfusions
    Ronald G Strauss
    Department of Pathology, University of Iowa Hospitals and Clinics, Iowa City, Iowa 52242 1009, USA
    Curr Opin Hematol 12:499-502. 2005
    ..e. trigger) in various clinical settings in patients with thrombocytopenia caused by marrow failure and the dose of platelets infused (i.e. number per each transfusion) for optimal hemostasis, feasibility, and safety...
  19. ncbi request reprint Donor T-lymphocyte infusion for unrelated allogeneic bone marrow transplantation with CD3+ T-cell-depleted graft
    C K Lee
    Department of Internal Medicine, College of Medicine, The University of Iowa, IA, USA
    Bone Marrow Transplant 31:121-8. 2003
    ..Although the incidence of relapse was low, the study suggests that the current scheme of DLI in unrelated TCD-BMT would not improve survival unless TRM decreases significantly...
  20. ncbi request reprint A dose escalation study for salvage chemotherapy in patients with refractory lymphoma prior to high-dose myeloablative therapy with stem cell transplantation
    C K Lee
    Department of Internal Medicine, Division of Hematology, Oncology, Blood and Marrow Transplantation, University of Iowa, College of Medicine, Iowa City, IA, USA
    Bone Marrow Transplant 29:647-52. 2002
    ..Currently, six are alive without evidence of disease, with a 3-year survival of 40%. Although preliminary, the regimen suggests acceptable toxicity and significant activity that warrants further study...
  21. ncbi request reprint Randomized trial assessing the feasibility and safety of biologic parents as RBC donors for their preterm infants
    R G Strauss
    Department of Pediatrics, Preventive Medicine and Environmental Health, and Pathology, The University of Iowa College of Medicine, Iowa City, IA 52242 1182, USA
    Transfusion 40:450-6. 2000
    ..Although biologic parents are likely candidates as donors of blood for their neonates, it has been suggested that their blood may be serologically incompatible with that of their infants...
  22. ncbi request reprint Cataracts in neutrophil donors stimulated with adrenal corticosteroids
    Z Ghodsi
    Department of Ophthalmology, DeGowin Blood Center, University of Iowa College of Medicine, Iowa City, Iowa 52242-1009, USA
    Transfusion 41:1464-8. 2001
    ..Other centers are urged to perform ophthalmologic examinations on repeat PMN donors to clarify this issue...
  23. ncbi request reprint Development of alloanti-Jka in a patient with hemolytic anemia due to autoanti-Jkb
    J E Grishaber
    Department of Pathology, University of Iowa College of Medicine, Iowa City 52242
    Am J Clin Pathol 98:542-4. 1992
    ..This case emphasizes the importance of additional serologic testing to detect alloantibodies in patients with broadly reactive warm autoantibodies...
  24. ncbi request reprint Cost-effectiveness of a limited-donor blood program for neonatal red cell transfusions
    P Hilsenrath
    Department of Preventive Medicine, College of Medicine, University of Iowa, Iowa City 52242, USA
    Transfusion 39:938-43. 1999
    ..Recently, to limit donor exposures, large volumes of RBCs are reserved for the long-term transfusion support of individual infants...
  25. ncbi request reprint Managing the anemia of prematurity: red blood cell transfusions versus recombinant erythropoietin
    R G Strauss
    University of Iowa College of Medicine, Iowa City, Iowa 52242-1182, USA
    Transfus Med Rev 15:213-23. 2001
    ..Recombinant erythropoietin therapy has not been widely adopted because it does not consistently reduce the need for red blood cell transfusions in very low-birth weight preterm infants...
  26. ncbi request reprint A red blood cell autoantibody with mimicking anti-E specificity
    Denis M Dwyre
    DeGowin Blood Center, University of Iowa, Iowa City, Iowa, USA
    Transfusion 44:1287-92. 2004
    ..e., they mimic antigenic specificity). Understanding both the pitfalls and the proper pathways to establish the diagnosis and to interpret the clinical significance of these mimicking antibodies is important for patient management...
  27. pmc Randomized trial of liberal versus restrictive guidelines for red blood cell transfusion in preterm infants
    Edward F Bell
    Department of Pediatrics, University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA
    Pediatrics 115:1685-91. 2005
    ..The objective of this study was to determine if restrictive guidelines for red blood cell (RBC) transfusions for preterm infants can reduce the number of transfusions without adverse consequences...
  28. pmc Posttransfusion 24-hour recovery and subsequent survival of allogeneic red blood cells in the bloodstream of newborn infants
    Ronald G Strauss
    Department of Pathology and Pediatrics, University of Iowa Roy J and Lucille A Carver College of Medicine, University of Iowa Hospitals and Clinics, Iowa City, Iowa 52242 1009, USA
    Transfusion 44:871-6. 2004
    ..We measured the posttransfusion recovery and intravascular survival of allogeneic RBCs stored up to 42 days to further elucidate their efficacy...
  29. pmc Long-term outcome of brain structure in premature infants: effects of liberal vs restricted red blood cell transfusions
    Peg C Nopoulos
    University of Iowa, 200 Hawkins Drive, Iowa City, IA 52242, USA
    Arch Pediatr Adolesc Med 165:443-50. 2011
    ..To assess the long-term outcome of brain structure in preterm infants, at an average age of 12 years, who received a red blood cell transfusion for anemia of prematurity...
  30. ncbi request reprint Etiology of differences in hematocrit between males and females: sequence-based polymorphisms in erythropoietin and its receptor
    S M Zeng
    Department of Obstetrics and Gynecology, University of Iowa College of Medicine, 200 Hawkins Dr, Iowa City, IA 52242-1080, USA
    J Gend Specif Med 4:35-40. 2001
    ..These findings offer new clues to understanding Hct variation in the general population and to elucidating mechanisms of controlling Hct levels...
  31. ncbi request reprint A randomized comparison of plateletpheresis with the same donors using four blood separators at a single blood center
    Grace C Tenorio
    Department of Pathology, University of Iowa Hospitals and Clinics, Iowa City, IA 52242, USA
    J Clin Apher 17:170-6. 2002
    ..Importantly, all four separators gave acceptable and comparable PLT yields (P < 0.05) with Spectra trending higher. The short process time and high RE together indicate highly efficient collections particularly by Amicus and Spectra...
  32. ncbi request reprint Prophylactic T cell infusion after T cell-depleted bone marrow transplantation in patients with refractory lymphoma
    C K Lee
    Department of Internal Medicine, Division of Hematology, Oncology, Blood and Marrow Transplantation, University of Iowa, College of Medicine, Iowa City, IA, USA
    Bone Marrow Transplant 29:615-20. 2002
    ..001. The study shows that patients with chronic GVHD have superior survivals, most probably related to a graft-versus-lymphoma effect, which could be modulated by prophylactic T cell infusion...
  33. ncbi request reprint Sequence-based polymorphisms in members of the apoptosis Bcl-2 gene family and their association with hematocrit level
    She Min Zeng
    Department of Obstetrics and Gynecology, University of Iowa, Iowa City, IA, USA
    J Gend Specif Med 6:36-42. 2003
    ..The Bcl-2 family mediates erythropoietin-dependent survival of erythroid progenitor cells and regulates erythropoiesis. We assessed for any association between Bcl-2 family nucleotide variation and hematocrit (HCT) in healthy blood donors...
  34. ncbi request reprint Comparative sensitivity of solid phase versus PEG enhancement assays for detection and identification of RBC antibodies
    Denis M Dwyre
    Department of Pathology, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA
    Transfus Apher Sci 35:19-23. 2006
    ..Because of ease and automation, Capture-R is popular as a screening test, but a more specific method may be helpful in order to identify truly significant alloantibodies...
  35. ncbi request reprint Association of single nucleotide polymorphisms in the thrombopoietin-receptor gene, but not the thrombopoietin gene, with differences in platelet count
    She Min Zeng
    Department of Obstetrics and Gynecology, University of Iowa, Iowa City, Iowa 52242 1080, USA
    Am J Hematol 77:12-21. 2004
    ..These new SNPs found for the human TPO and TPOR genes help explain variations in blood PLT counts and may be useful in patient studies related to the roles of TPO and/or TPOR in disease...
  36. ncbi request reprint Clinical safety of platelets photochemically treated with amotosalen HCl and ultraviolet A light for pathogen inactivation: the SPRINT trial
    Edward Snyder
    Yale University Medical School, Yale New Haven Hospital, New Haven, Connecticut, USA
    Transfusion 45:1864-75. 2005
    ..Hemostatic equivalency was demonstrated. The proportion of patients with Grade 2 bleeding was not inferior for PCT PLTs...
  37. ncbi request reprint Therapeutic efficacy and safety of platelets treated with a photochemical process for pathogen inactivation: the SPRINT Trial
    Jeffrey McCullough
    University of Minnesota, MMC 609, 420 Delaware Street SE, Minneapolis, MN 55455, USA
    Blood 104:1534-41. 2004
    ..02). The incidence of grade 2 bleeding was equivalent for PCT and conventional platelets, although posttransfusion platelet count increments and days to next transfusion were decreased for PCT compared with conventional platelets...
  38. ncbi request reprint Pathogen inactivation of platelets with a photochemical treatment with amotosalen HCl and ultraviolet light: process used in the SPRINT trial
    Alvaro Pineda
    Mayo Clinic, Rochester, Minnesota, USA
    Transfusion 46:562-71. 2006
    ..The system comprises PLT additive solution (PAS III), amotosalen HCl, a compound adsorption device (CAD), a microprocessor-controlled ultraviolet A light source, and a commercially assembled system of interconnected plastic containers...
  39. doi request reprint Risks of clinically significant thrombocytopenia and/or lymphocytopenia in donors after multiple plateletpheresis collections
    Ronald G Strauss
    Transfusion 48:1274-8. 2008
  40. ncbi request reprint Sickle cell patients deserve controlled recommendations
    Ronald G Strauss
    Transfusion 42:658-9; author reply 659-60. 2002
  41. ncbi request reprint Platelet dose consistency and its effect on the number of platelet transfusions for support of thrombocytopenia: an analysis of the SPRINT trial of platelets photochemically treated with amotosalen HCl and ultraviolet A light
    Scott Murphy
    American Red Cross Blood Services, Philadelphia, Pennsylvania, USA
    Transfusion 46:24-33. 2006
    ..PLT dose was analyzed to determine the impact of the number of PLTs transfused on transfusion requirements...
  42. ncbi request reprint RBCs labeled at two biotin densities permit simultaneous and repeated measurements of circulating RBC volume
    Donald M Mock
    Department of Biochemistry and Molecular Biology 516, University of Arkansas for Medical Sciences, 4301 W Markham Street, Little Rock, AR 72205, USA
    Transfusion 44:431-7. 2004
    ....
  43. ncbi request reprint Glucocorticoid stimulation of neutrophil donors: a medical, scientific, and ethical dilemma
    Ronald G Strauss
    Transfusion 45:1697-9. 2005
  44. ncbi request reprint Low-dose prophylactic platelet transfusions: time for further study, but too early for routine clinical practice
    Ronald G Strauss
    Transfusion 44:1680-2. 2004
  45. ncbi request reprint All formulations of hydroxyethyl starch are not the same
    Ronald G Strauss
    Transfusion 47:1329-30; author reply 1330-1. 2007

Research Grants1

  1. Transfusion Medicine/Hemostasis Clinical Research Network
    Ronald Strauss; Fiscal Year: 2007
    ..Many millions more have problems with thrombocytopenia, neutropenia and anemia. This network has established a building block for future research to help treat and combat these problems. UNIVERSITY OF IOWA CRITIQUES ..