Nicholas James Strausfeld

Summary

Affiliation: University of Arizona
Country: USA

Publications

  1. ncbi request reprint Organization of olfactory and multimodal afferent neurons supplying the calyx and pedunculus of the cockroach mushroom bodies
    N J Strausfeld
    Arizona Research Laboratories, Division of Neurobiology, The University of Arizona, Tucson 85721, USA
    J Comp Neurol 409:603-25. 1999
  2. pmc A precocious adult visual center in the larva defines the unique optic lobe of the split-eyed whirligig beetle Dineutus sublineatus
    Chan Lin
    Graduate Interdisciplinary Program in Entomology and Insect Science, University of Arizona, Tucson, AZ, 85721, USA
    Front Zool 10:7. 2013
  3. doi request reprint Deep homology of arthropod central complex and vertebrate basal ganglia
    Nicholas J Strausfeld
    Department of Neuroscience, School of Mind, Brain and Behavior, University of Arizona, Tucson, AZ 85721, USA
    Science 340:157-61. 2013
  4. pmc Dynamics of glutamatergic signaling in the mushroom body of young adult Drosophila
    Irina Sinakevitch
    Laboratoire de Neurobiologie, CNRS UMR 7637, ESPCI ParisTech, 10 rue Vauquelin, 75231 Paris Cedex 5, France
    Neural Dev 5:10. 2010
  5. pmc Arthropod phylogeny: onychophoran brain organization suggests an archaic relationship with a chelicerate stem lineage
    Nicholas J Strausfeld
    Division of Neurobiology and The Center for Insect Science, University of Arizona, Tucson, AZ 85721, USA
    Proc Biol Sci 273:1857-66. 2006
  6. ncbi request reprint Visual system of calliphorid flies: organization of optic glomeruli and their lobula complex efferents
    Nicholas J Strausfeld
    Arizona Research Laboratories Division of Neurobiology, University of Arizona, Tucson, Arizona 85721, USA
    J Comp Neurol 500:166-88. 2007
  7. ncbi request reprint Organization of local interneurons in optic glomeruli of the dipterous visual system and comparisons with the antennal lobes
    Nicholas J Strausfeld
    Division of Neurobiology, Arizona Research Laboratories, University of Arizona, Tucson, Arizona 85721, USA
    Dev Neurobiol 67:1267-88. 2007
  8. doi request reprint Johann Flögel (1834-1918) and the birth of comparative insect neuroanatomy and brain nomenclature
    Nicholas J Strausfeld
    Arizona Research Laboratories, Division of Neurobiology, 611 Gould Simpson, University of Arizona, Tucson, AZ 85721, USA
    Arthropod Struct Dev 37:434-41. 2008
  9. doi request reprint Ground plan of the insect mushroom body: functional and evolutionary implications
    Nicholas J Strausfeld
    Arizona Research Laboratories, Division of Neurobiology, University of Arizona, Tucson, Arizona 85721, USA
    J Comp Neurol 513:265-91. 2009
  10. pmc Brain organization and the origin of insects: an assessment
    Nicholas James Strausfeld
    Division of Neurobiology and The Center for Insect Science, University of Arizona, Tucson, AZ 85721, USA
    Proc Biol Sci 276:1929-37. 2009

Research Grants

  1. Neurobiology of a Simple Oculomotor System: Circuitry
    NICHOLAS STRAUSFELD; Fiscal Year: 2006
  2. Neurobiology of a Simple Oculomotor System: Circuitry
    NICHOLAS STRAUSFELD; Fiscal Year: 2007
  3. Conf Proposal:Gordon Research Conf on Neuroethology 2005
    NICHOLAS STRAUSFELD; Fiscal Year: 2005
  4. NEUROBIOLOGY OF SIMPLE OCULOMOTOR SYSTEM
    NICHOLAS STRAUSFELD; Fiscal Year: 2001
  5. NEUROBIOLOGY OF SIMPLE OCULOMOTOR SYSTEM
    NICHOLAS STRAUSFELD; Fiscal Year: 1993

Detail Information

Publications40

  1. ncbi request reprint Organization of olfactory and multimodal afferent neurons supplying the calyx and pedunculus of the cockroach mushroom bodies
    N J Strausfeld
    Arizona Research Laboratories, Division of Neurobiology, The University of Arizona, Tucson 85721, USA
    J Comp Neurol 409:603-25. 1999
    ..The relevance of multimodal supply to the calyx in odorant discrimination is discussed as are comparisons between mushroom body organization in this phylogenetically basal neopteran and other taxa...
  2. pmc A precocious adult visual center in the larva defines the unique optic lobe of the split-eyed whirligig beetle Dineutus sublineatus
    Chan Lin
    Graduate Interdisciplinary Program in Entomology and Insect Science, University of Arizona, Tucson, AZ, 85721, USA
    Front Zool 10:7. 2013
    ..We show here, for the first time, the peculiar optic lobe organization of the larval and adult whirligig beetle Dineutus sublineatus...
  3. doi request reprint Deep homology of arthropod central complex and vertebrate basal ganglia
    Nicholas J Strausfeld
    Department of Neuroscience, School of Mind, Brain and Behavior, University of Arizona, Tucson, AZ 85721, USA
    Science 340:157-61. 2013
    ..The observed multitude of similarities suggests deep homology of arthropod central complex and vertebrate basal ganglia circuitries underlying the selection and maintenance of behavioral actions...
  4. pmc Dynamics of glutamatergic signaling in the mushroom body of young adult Drosophila
    Irina Sinakevitch
    Laboratoire de Neurobiologie, CNRS UMR 7637, ESPCI ParisTech, 10 rue Vauquelin, 75231 Paris Cedex 5, France
    Neural Dev 5:10. 2010
    ..In a Drosophila model of fragile X syndrome, the main cause of inherited mental retardation, treatment with metabotropic Glu receptor (mGluR) antagonists can rescue memory deficits and MB structural defects...
  5. pmc Arthropod phylogeny: onychophoran brain organization suggests an archaic relationship with a chelicerate stem lineage
    Nicholas J Strausfeld
    Division of Neurobiology and The Center for Insect Science, University of Arizona, Tucson, AZ 85721, USA
    Proc Biol Sci 273:1857-66. 2006
    ..Neuroanatomical evidence suggests that the organization of the onychophoran brain is similar to that of the brains of chelicerates...
  6. ncbi request reprint Visual system of calliphorid flies: organization of optic glomeruli and their lobula complex efferents
    Nicholas J Strausfeld
    Arizona Research Laboratories Division of Neurobiology, University of Arizona, Tucson, Arizona 85721, USA
    J Comp Neurol 500:166-88. 2007
    ....
  7. ncbi request reprint Organization of local interneurons in optic glomeruli of the dipterous visual system and comparisons with the antennal lobes
    Nicholas J Strausfeld
    Division of Neurobiology, Arizona Research Laboratories, University of Arizona, Tucson, Arizona 85721, USA
    Dev Neurobiol 67:1267-88. 2007
    ..The present results demonstrate that future studies must consider the roles of other senses in visual processing...
  8. doi request reprint Johann Flögel (1834-1918) and the birth of comparative insect neuroanatomy and brain nomenclature
    Nicholas J Strausfeld
    Arizona Research Laboratories, Division of Neurobiology, 611 Gould Simpson, University of Arizona, Tucson, AZ 85721, USA
    Arthropod Struct Dev 37:434-41. 2008
    ..Here we give a biographical sketch of his life and summarize his remarkable achievements...
  9. doi request reprint Ground plan of the insect mushroom body: functional and evolutionary implications
    Nicholas J Strausfeld
    Arizona Research Laboratories, Division of Neurobiology, University of Arizona, Tucson, Arizona 85721, USA
    J Comp Neurol 513:265-91. 2009
    ..Archaeognathan brains are like those of higher malacostracans, which lack mushroom bodies but have elaborate olfactory centers laterally in the brain...
  10. pmc Brain organization and the origin of insects: an assessment
    Nicholas James Strausfeld
    Division of Neurobiology and The Center for Insect Science, University of Arizona, Tucson, AZ 85721, USA
    Proc Biol Sci 276:1929-37. 2009
    ..Neural organization in brain centres, comprising olfactory pathways, optic lobes and a central neuropil that is thought to play a cardinal role in multi-joint movement, support affinities between insects and malacostracan crustaceans...
  11. pmc Dimorphic olfactory lobes in the arthropoda
    NICHOLAS STRAUSFELD
    ARL Division of Neurobiology and Center for Insect Science, University of Arizona, Tucson, Arizona 85721, USA
    Ann N Y Acad Sci 1170:487-96. 2009
    ..Other than a single description, there is no evidence for similar structures occurring in the Crustacea, suggesting that the evolution of dimorphic olfactory systems may typify terrestrial arthropods...
  12. doi request reprint A new view of insect-crustacean relationships II. Inferences from expressed sequence tags and comparisons with neural cladistics
    David R Andrew
    Department of Neuroscience, University of Arizona, 1040 E 4th St, Gould Simpson Bldg 611, Tucson, AZ 85721, USA
    Arthropod Struct Dev 40:289-302. 2011
    ..Whereas the phenomenon of evolved simplification may be widespread, it is largely invisible to molecular techniques unless these are performed in conjunction with morphology-based strategies...
  13. doi request reprint A new view of insect-crustacean relationships I. Inferences from neural cladistics and comparative neuroanatomy
    Nicholas J Strausfeld
    Department of Neuroscience, University of Arizona, 1040 E 4th St, Gould Simpson Bldg 611, Tucson, AZ 85721, USA
    Arthropod Struct Dev 40:276-88. 2011
    ..The present study resolves branchiopod crustaceans as descendents of an ancestor with a complex brain, which means that they have evolved secondary simplification and the loss or reduction of numerous neural systems...
  14. ncbi request reprint Representation of the calyces in the medial and vertical lobes of cockroach mushroom bodies
    N J Strausfeld
    Arizona Research Laboratories, Division of Neurobiology, The University of Arizona, Tucson 85721, USA
    J Comp Neurol 409:626-46. 1999
    ..There are profound similarities between the mushroom bodies of Periplaneta, an evolutionarily basal taxon, and those of Drosophila melanogaster and the honey bee...
  15. ncbi request reprint Olfactory systems: common design, uncommon origins?
    N J Strausfeld
    Arizona Research Laboratories ARL Division of Neurobiology University of Arizona PO Box 210077, Tucson, Arizona, 85721 0077, USA
    Curr Opin Neurobiol 9:634-9. 1999
    ..Whereas there is a case to be made for homology among members of the two great protostome clades (the ecdysozoans and lophotrochozoans), the position of the craniates remains ambiguous...
  16. ncbi request reprint Parallel organization in honey bee mushroom bodies by peptidergic Kenyon cells
    N J Strausfeld
    Division of Neurobiology, Arizona Research Laboratories, The University of Arizona, Tucson, Arizona 85721, USA
    J Comp Neurol 424:179-95. 2000
    ..The functional and evolutionary significance of the results is discussed...
  17. ncbi request reprint Multimodal efferent and recurrent neurons in the medial lobes of cockroach mushroom bodies
    Y Li
    Arizona Research Laboratories, Division of Neurobiology, The University of Arizona, Tucson 85721, USA
    J Comp Neurol 409:647-63. 1999
    ....
  18. ncbi request reprint Exploitation of an ancient escape circuit by an avian predator: prey sensitivity to model predator display in the field
    P G Jabloński
    ARL Division of Neurobiology, University of Arizona, Tucson, Ariz, USA
    Brain Behav Evol 56:94-106. 2000
    ..We propose that the tuning properties of these neural pathways might have contributed to the evolution of foraging displays in flush-pursuing birds...
  19. ncbi request reprint Chemical neuroanatomy of the fly's movement detection pathway
    Irina Sinakevitch
    Arizona Research Laboratories, Division of Neurobiology, University of Arizona, Tucson, Arizona 85721, USA
    J Comp Neurol 468:6-23. 2004
    ....
  20. ncbi request reprint Visual system of calliphorid flies: motion- and orientation-sensitive visual interneurons supplying dorsal optic glomeruli
    Jun Ya Okamura
    Arizona Research Laboratories, Division of Neurobiology, University of Arizona, Tucson, Arizona, 85721, USA
    J Comp Neurol 500:189-208. 2007
    ..The present results are discussed with respect to the behavioral significance of oriented motion discrimination by flies and other insects, and with respect to neuroanatomical data demonstrating the organization of deep visual neuropils...
  21. ncbi request reprint A simple mushroom body in an African scarabid beetle
    Mattias C Larsson
    ARL Division of Neurobiology, University of Arizona, Tucson, Arizona 85721, USA
    J Comp Neurol 478:219-32. 2004
    ..In either case, cellular organization in Pachnoda's mushroom body is simple compared with that of other taxa...
  22. ncbi request reprint Octopamine-like immunoreactivity in the honey bee and cockroach: comparable organization in the brain and subesophageal ganglion
    Irina Sinakevitch
    Arizona Research Laboratories, Division of Neurobiology, University of Arizona, Tucson, Arizona 85721, USA
    J Comp Neurol 488:233-54. 2005
    ..The present observations are discussed with respect to possible roles of octopamine in sensory integration and association...
  23. ncbi request reprint Retinotopic pathways providing motion-selective information to the lobula from peripheral elementary motion-detecting circuits
    John K Douglass
    Division of Neurobiology, Arizona Research Laboratories, University of Arizona, Tucson, Arizona 85721, USA
    J Comp Neurol 457:326-44. 2003
    ..The results are discussed in the context of other intracellular recordings from retinotopic neurons and with analogous findings from mammalian visual systems...
  24. ncbi request reprint A unique mushroom body substructure common to basal cockroaches and to termites
    Sarah M Farris
    Division of Neurobiology, Arizona Research Laboratories, University of Arizona, Tucson, Arizona 85721, USA
    J Comp Neurol 456:305-20. 2003
    ..It thus appears that the evolution of the Dictyoptera has been accompanied by increasing complexity of the mushroom bodies, achieved in part through the further specialization and elaboration of a subset of Kenyon cells...
  25. ncbi request reprint Anatomical organization of retinotopic motion-sensitive pathways in the optic lobes of flies
    John K Douglass
    Arizona Research Laboratories, Division of Neurobiology, University of Arizona, Tucson, Arizona 85721, USA
    Microsc Res Tech 62:132-50. 2003
    ..Microsc. Res. Tech. 62:132-150, 2003...
  26. ncbi request reprint Learning with half a brain
    David D Lent
    Arizona Research Laboratories Division of Neurobiology, The University of Arizona, Tucson, Arizona, USA
    Dev Neurobiol 67:740-51. 2007
    ....
  27. ncbi request reprint Diverse speed response properties of motion sensitive neurons in the fly's optic lobe
    John K Douglass
    Arizona Research Laboratories, Division of Neurobiology, 611 Gould Simpson Bldg, University of Arizona, Tucson, AZ 85721, USA
    J Comp Physiol A Neuroethol Sens Neural Behav Physiol 193:233-47. 2007
    ..Two additional recordings are suggestive of acceleration-selectivity, a potentially useful visual capability that is of uncertain functional significance for arthropods...
  28. ncbi request reprint Development-dependent and -independent ubiquitin expression in divisions of the cockroach mushroom body
    Sheena M Brown
    Arizona Research Laboratories, Division of Neurobiology, The University of Arizona, Tucson, 85721, USA
    J Comp Neurol 496:556-71. 2006
    ..This pattern of ubiquitin expression suggests that the gamma lobe circuitry undergoes continuous modification independent of development...
  29. ncbi request reprint Sign-conserving amacrine neurons in the fly's external plexiform layer
    John K Douglass
    Arizona Research Laboratories, Division of Neurobiology, University of Arizona, Tucson, 85721, USA
    Vis Neurosci 22:345-58. 2005
    ..Thus, the localized spatial responses and receptor-like temporal response properties of amacrines are consistent with possible roles in lateral inhibition, motion processing, or orientation processing...
  30. pmc Memory consolidation and gene expression in Periplaneta americana
    Marianna Pintér
    Arizona Research Laboratories, Division of Neurobiology, The University of Arizona, Tucson, Arizona 85721, USA
    Learn Mem 12:30-8. 2005
    ..These transcripts will be used as one of several tools in the identification of neuronal circuits, such as in the mushroom bodies, that are implicated in memory consolidation...
  31. ncbi request reprint The computational basis of an identified neuronal circuit for elementary motion detection in dipterous insects
    Charles M Higgins
    Arizona Research Laboratories, Division of Neurobiology, University of Arizona, Tucson, AZ 85721, USA
    Vis Neurosci 21:567-86. 2004
    ..In addition, this model suggests that the retinotopic motion information provided to wide-field motion-sensitive cells in the lobula is derived from a less refined stage of processing than motion inputs to the lobula plate...
  32. ncbi request reprint Organization of the honey bee mushroom body: representation of the calyx within the vertical and gamma lobes
    Nicholas J Strausfeld
    Division of Neurobiology, Arizona Research Laboratories, The University of Arizona, Tucson, Arizona 85721, USA
    J Comp Neurol 450:4-33. 2002
    ..The present findings suggest the need for critical reinterpretation of studies that have been predicated on early descriptions of the mushroom body's lobes...
  33. ncbi request reprint Comparison of octopamine-like immunoreactivity in the brains of the fruit fly and blow fly
    Irina Sinakevitch
    Arizona Research Laboratories Division of Neurobiology, University of Arizona, Tucson, Arizona 85719, USA
    J Comp Neurol 494:460-75. 2006
    ..The results are also discussed with respect to recent studies on octopamine-immunoreactive organization in honey bees and cockroaches and the suggested roles of octopamine in sensory processing, learning, and memory...
  34. ncbi request reprint The mushroom bodies of Drosophila melanogaster: an immunocytological and golgi study of Kenyon cell organization in the calyces and lobes
    Nicholas J Strausfeld
    Arizona Research Laboratories, Division of Neurobiology, The University of Arizona, Tucson, Arizona 85721, USA
    Microsc Res Tech 62:151-69. 2003
    ..As in honey bees, GABAergic processes densely invade Drosophila's calyces, which also contain a sparse but uniform distribution of octopaminergic elements. Microsc. Res. Tech. 62:151-169, 2003...
  35. ncbi request reprint Dissection of the peripheral motion channel in the visual system of Drosophila melanogaster
    Jens Rister
    Lehrstuhl für Genetik und Neurobiologie, Universitat Wurzburg, Am Hubland, 97074, Wurzburg, Germany
    Neuron 56:155-70. 2007
    ..At low contrast, L1 and L2 depend upon each other for motion processing. Of the two minor pathways, amc/T1 specifically enhances the L1 pathway at intermediate contrast. L3 appears not to contribute to motion but to orientation behavior...
  36. pmc Organization of optic lobes that support motion detection in a semiterrestrial crab
    Julieta Sztarker
    Laboratorio de Neurobiologia de la Memoria, Depto Fisiologia, Biologia Molecular y Celular, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Argentina
    J Comp Neurol 493:396-411. 2005
    ..We discuss the significance of commonalties across taxa with respect to the organization of the lamina and medulla and contrasts these with possible taxon-specific arrangements of deeper neuropils that support systems of matched filters...
  37. ncbi request reprint Spatial learning in the restrained American cockroach Periplaneta americana
    Hyung Wook Kwon
    Dept of Biological Sciences, 6270 Medical Research Building III, Vanderbilt University, 465 21st Avenue South, Nashville, TN 37235, USA
    J Exp Biol 207:377-83. 2004
    ..Possible mechanisms, such as retinotopic matching versus angular matching, are discussed...
  38. ncbi request reprint Organization of Kenyon cells in subdivisions of the mushroom bodies of a lepidopteran insect
    Marcus Sjöholm
    Department of Crop Science, Swedish University of Agricultural Sciences, SE 230 53 Alnarp, Sweden
    J Comp Neurol 491:290-304. 2005
    ....
  39. doi request reprint Global and local modulatory supply to the mushroom bodies of the moth Spodoptera littoralis
    Irina Sinakevitch
    IBDML UMR 6216, Case 907 Parc Scientifique de Luminy, 13288 Marseille, Cedex 9, France
    Arthropod Struct Dev 37:260-72. 2008
    ..The results suggest that in addition to longitudinal divisions of the lobes, circuits in the calyces and lobes are likely to be independently modulated...
  40. ncbi request reprint Development and morphology of class II Kenyon cells in the mushroom bodies of the honey bee, Apis mellifera
    Sarah M Farris
    Department of Biology, West Virginia University, Morgantown, West Virginia 26506, USA
    J Comp Neurol 474:325-39. 2004
    ..The observed variations in morphology indicate that subpopulations of Class II Kenyon cells in the honey bee can likely be further defined by significant differences in their specific connections and functions within the mushroom bodies...

Research Grants19

  1. Neurobiology of a Simple Oculomotor System: Circuitry
    NICHOLAS STRAUSFELD; Fiscal Year: 2006
    ..It will also lead to the implementation of silicon-based circuits that enable motion detection and shape discrimination and potentially provide the basis for a visual prosthetic device. ..
  2. Neurobiology of a Simple Oculomotor System: Circuitry
    NICHOLAS STRAUSFELD; Fiscal Year: 2007
    ..It will also lead to the implementation of silicon-based circuits that enable motion detection and shape discrimination and potentially provide the basis for a visual prosthetic device. ..
  3. Conf Proposal:Gordon Research Conf on Neuroethology 2005
    NICHOLAS STRAUSFELD; Fiscal Year: 2005
    ..The conference is intended for the broad neuroethological community at all professional levels including advanced graduate and postdoctoral trainees. ..
  4. NEUROBIOLOGY OF SIMPLE OCULOMOTOR SYSTEM
    NICHOLAS STRAUSFELD; Fiscal Year: 2001
    ....
  5. NEUROBIOLOGY OF SIMPLE OCULOMOTOR SYSTEM
    NICHOLAS STRAUSFELD; Fiscal Year: 1993
    ..A complete description of motor control in this model will contribute a major step towards understanding circuitry for complex oculomotor behaviour and the role of uniquely identified neurons in visual pursuit and interception...