Steven P Stratton

Summary

Affiliation: University of Arizona
Country: USA

Publications

  1. ncbi request reprint Treatment and prevention of intraepithelial neoplasia: an important target for accelerated new agent development
    Joyce A O'Shaughnessy
    Baylor Sammons Cancer Center, US Oncology, Collins 5, 3535 Worth Street, Dallas, TX 75246, USA
    Clin Cancer Res 8:314-46. 2002
  2. doi request reprint Phase 1 study of topical perillyl alcohol cream for chemoprevention of skin cancer
    Steven P Stratton
    Arizona Cancer Center and Department of Medicine, College of Medicine, University of Arizona, Tucson, Arizona 85724, USA
    Nutr Cancer 60:325-30. 2008
  3. pmc A phase 2a study of topical perillyl alcohol cream for chemoprevention of skin cancer
    Steven P Stratton
    Department of Medicine, University of Arizona, Tucson, 85724, USA
    Cancer Prev Res (Phila) 3:160-9. 2010
  4. doi request reprint Oral selenium supplementation has no effect on prostate-specific antigen velocity in men undergoing active surveillance for localized prostate cancer
    M Suzanne Stratton
    Arizona Cancer Center, University of Arizona, Tucson, 85724, USA
    Cancer Prev Res (Phila) 3:1035-43. 2010
  5. doi request reprint Association of obesity and smoking with PSA and PSA velocity in men with prostate cancer
    Amit M Algotar
    Arizona Cancer Center, University of Arizona, Tucson, USA
    Am J Mens Health 5:272-8. 2011
  6. pmc Phase 3 clinical trial investigating the effect of selenium supplementation in men at high-risk for prostate cancer
    Amit M Algotar
    The University of Arizona Cancer Center, University of Arizona, Tucson, Arizona 85724, USA
    Prostate 73:328-35. 2013
  7. pmc Functional protein pathway activation mapping of the progression of normal skin to squamous cell carcinoma
    Janine G Einspahr
    University of Arizona Cancer Center, 1515 North Campbell Avenue, Tucson, AZ 85724, USA
    Cancer Prev Res (Phila) 5:403-13. 2012
  8. pmc No effect of selenium supplementation on serum glucose levels in men with prostate cancer
    Amit M Algotar
    Arizona Cancer Center, University of Arizona, Tucson, AZ 85724, USA
    Am J Med 123:765-8. 2010
  9. doi request reprint Cross-validation of murine UV signal transduction pathways in human skin
    Janine G Einspahr
    Department of Medicine, University of Arizona, Tucson, AZ, USA
    Photochem Photobiol 84:463-76. 2008
  10. ncbi request reprint Development of an HPLC method for the analysis of Apomine in a topical cream formulation
    Philip J Kuehl
    College of Pharmacy, University of Arizona, 1703 E Mabel St, Tucson, AZ 85721, USA
    J Pharm Biomed Anal 40:975-80. 2006

Collaborators

Detail Information

Publications17

  1. ncbi request reprint Treatment and prevention of intraepithelial neoplasia: an important target for accelerated new agent development
    Joyce A O'Shaughnessy
    Baylor Sammons Cancer Center, US Oncology, Collins 5, 3535 Worth Street, Dallas, TX 75246, USA
    Clin Cancer Res 8:314-46. 2002
    ..The IEN Task Force proposes several clinical trial designs that provide practical and feasible approaches to the rapid development of new agents to treat and prevent precancer...
  2. doi request reprint Phase 1 study of topical perillyl alcohol cream for chemoprevention of skin cancer
    Steven P Stratton
    Arizona Cancer Center and Department of Medicine, College of Medicine, University of Arizona, Tucson, Arizona 85724, USA
    Nutr Cancer 60:325-30. 2008
    ..However, there was no significant difference between lesions appearing on the POH treated forearm vs. the placebo-treated forearm...
  3. pmc A phase 2a study of topical perillyl alcohol cream for chemoprevention of skin cancer
    Steven P Stratton
    Department of Medicine, University of Arizona, Tucson, 85724, USA
    Cancer Prev Res (Phila) 3:160-9. 2010
    ..These results suggest that whereas our karyometric analyses can detect a modest effect of POH in sun-damaged skin, improved delivery into the epidermis may be necessary...
  4. doi request reprint Oral selenium supplementation has no effect on prostate-specific antigen velocity in men undergoing active surveillance for localized prostate cancer
    M Suzanne Stratton
    Arizona Cancer Center, University of Arizona, Tucson, 85724, USA
    Cancer Prev Res (Phila) 3:1035-43. 2010
    ..On the contrary, supplementation with high-dose selenium was observed to be a risk factor for increased PSA velocity in men with high baseline plasma selenium concentrations...
  5. doi request reprint Association of obesity and smoking with PSA and PSA velocity in men with prostate cancer
    Amit M Algotar
    Arizona Cancer Center, University of Arizona, Tucson, USA
    Am J Mens Health 5:272-8. 2011
    ..57 ng/mL/year (p = .04). Further studies with larger sample sizes and study designs specific to above exposures are needed before recommendations can be made to reduce weight or reduce/quit smoking...
  6. pmc Phase 3 clinical trial investigating the effect of selenium supplementation in men at high-risk for prostate cancer
    Amit M Algotar
    The University of Arizona Cancer Center, University of Arizona, Tucson, Arizona 85724, USA
    Prostate 73:328-35. 2013
    ..This study was conducted to investigate the effect of Se supplementation on prostate cancer incidence in men at high risk for prostate cancer...
  7. pmc Functional protein pathway activation mapping of the progression of normal skin to squamous cell carcinoma
    Janine G Einspahr
    University of Arizona Cancer Center, 1515 North Campbell Avenue, Tucson, AZ 85724, USA
    Cancer Prev Res (Phila) 5:403-13. 2012
    ..Pathway activation mapping of SCC compared with AK revealed several interconnected networks that could be targeted with drug therapy for potential chemoprevention and therapeutic applications...
  8. pmc No effect of selenium supplementation on serum glucose levels in men with prostate cancer
    Amit M Algotar
    Arizona Cancer Center, University of Arizona, Tucson, AZ 85724, USA
    Am J Med 123:765-8. 2010
    ....
  9. doi request reprint Cross-validation of murine UV signal transduction pathways in human skin
    Janine G Einspahr
    Department of Medicine, University of Arizona, Tucson, AZ, USA
    Photochem Photobiol 84:463-76. 2008
    ..Validation of murine models in human skin will aid in development of effective skin cancer chemoprevention and prevention strategies...
  10. ncbi request reprint Development of an HPLC method for the analysis of Apomine in a topical cream formulation
    Philip J Kuehl
    College of Pharmacy, University of Arizona, 1703 E Mabel St, Tucson, AZ 85721, USA
    J Pharm Biomed Anal 40:975-80. 2006
    ..This report demonstrates that this method is effective for quantification of Apomine in a cream formulation...
  11. ncbi request reprint Chemoprevention of human skin cancer
    Janine G Einspahr
    Arizona Cancer Center, University of Arizona, 1515, North Campbell Avenue, Tucson 85724, USA
    Crit Rev Oncol Hematol 41:269-85. 2002
    ....
  12. ncbi request reprint Increased skin carcinogenesis in a keratinocyte directed thioredoxin-1 transgenic mouse
    Debbie Mustacich
    Arizona Cancer Center and Department of Pathology, University of Arizona, Tucson, AZ 85724, USA
    Carcinogenesis 25:1983-9. 2004
    ..Thus, increased thioredoxin-1 in keratinocytes acts as an enhancer of carcinogenesis in the DMBA/TPA two-stage model of skin carcinogenesis in mice...
  13. ncbi request reprint A Phase I pharmacokinetic and pharmacodynamic study of PX-12, a novel inhibitor of thioredoxin-1, in patients with advanced solid tumors
    Ramesh K Ramanathan
    Division of Hematology Oncology, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    Clin Cancer Res 13:2109-14. 2007
    ..Objectives of this study were to determine safety, tolerability, pharmacodynamics, and pharmacokinetics of PX-12, a small-molecule inhibitor of Trx-1...
  14. ncbi request reprint Cytotoxic activity of Apomine is due to a novel membrane-mediated cytolytic mechanism independent of apoptosis in the A375 human melanoma cell line
    Alan Pourpak
    Arizona Cancer Center, The University of Arizona, 1515 N, Campbell Avenue, Tucson, AZ 85724, USA
    Invest New Drugs 25:107-14. 2007
    ..These data suggest that Apomine induces cell death through a novel plasma membrane-mediated cytolytic pathway, independent of caspase-3 activation and N-Ras farnesylation...
  15. doi request reprint Effect of aspirin, other NSAIDs, and statins on PSA and PSA velocity
    Amit M Algotar
    Arizona Cancer Center, University of Arizona, Tucson, Arizona, USA
    Prostate 70:883-8. 2010
    ..Aspirin, other non-steroidal anti-inflammatory drugs (NSAIDs), and statins have been associated with lower risk of prostate cancer and its progression, though results have been inconsistent...
  16. ncbi request reprint An HPLC method for quantitation of perillyl alcohol in a topical pharmaceutical cream formulation
    Abhishek Gupta
    Cardinal Health, Inhalation Formulation, P O Box 13341, Research Triangle Park, NC 27709, USA
    J Pharm Biomed Anal 37:447-52. 2005
    ..The high sensitivity assay utilizes a small (5 microL) injection volume for the accurate and precise analysis of perillyl alcohol from a complex cream formulation...