Research Topics
| Stephen StrakowskiSummaryAffiliation: University of Cincinnati Country: USA Publications
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Publications
The functional neuroanatomy of bipolar disorder: a consensus modelStephen M Strakowski
Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
Bipolar Disord 14:313-25. 2012....
Outcome following a first manic episode: cross-national US and Taiwan comparisonStephen M Strakowski
Division of Bipolar Disorders Research, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
Bipolar Disord 9:820-7. 2007..Therefore, the aim of this study was to identify differential and shared outcome predictors in first-episode manic bipolar patients in Cincinnati, OH, USA and Taipei, Taiwan...
Magnetic resonance imaging brain activation in first-episode bipolar mania during a response inhibition taskStephen M Strakowski
Division of Bipolar Disorders Research, Department of Psychiatry, and the Centefor Imaging Research, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA
Early Interv Psychiatry 2:225-33. 2008..Impulsivity is common in bipolar disorder, especially during mania. Understanding the functional neuroanatomy of response inhibition, one component of impulsivity, might clarify the neural substrate of bipolar disorder...- A preliminary FMRI study of sustained attention in euthymic, unmedicated bipolar disorderStephen M Strakowski
Bipolar and Psychotic Disorders Research Program, University of Cincinnati College of Medicine, OH 45267 0583, USA
Neuropsychopharmacology 29:1734-40. 2004..Since the differences occurred in euthymia, they may represent trait, rather than state, abnormalities of brain function in bipolar disorder... - Characterizing impulsivity in maniaStephen M Strakowski
Division of Bipolar Disorders Research, Universtiy of Cincinnati College of Medicine, Cincinnati, OH, USA
Bipolar Disord 11:41-51. 2009.... - Impulsivity across the course of bipolar disorderStephen M Strakowski
Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, 231 Albert Sabin Way ML0583, Cincinnati, OH 45267 0583, USA
Bipolar Disord 12:285-97. 2010..To determine whether abnormalities of impulse control persist across the course of bipolar disorder, thereby representing potential state markers and endophenotypes... - Functional magnetic resonance imaging brain activation in bipolar mania: evidence for disruption of the ventrolateral prefrontal-amygdala emotional pathwayStephen M Strakowski
Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0559 USA
Biol Psychiatry 69:381-8. 2011..We used functional magnetic resonance imaging (fMRI) to study manic bipolar subjects as they performed a cognitive task designed to examine the ventrolateral prefrontal emotional arousal network... - Effects of co-occurring alcohol abuse on the course of bipolar disorder following a first hospitalization for maniaStephen M Strakowski
Division of Bipolar Disorders Research, University of Cincinnati College of Medicine, 231 Albert Sabin Way ML0559, PO Box 670559, Cincinnati, OH 45267 0559, USA
Arch Gen Psychiatry 62:851-8. 2005..Alcohol-use disorders are common co-occurring conditions affecting bipolar patients, and this co-occurrence is negatively associated with outcome... - Abnormal FMRI brain activation in euthymic bipolar disorder patients during a counting Stroop interference taskStephen M Strakowski
Center for Imaging Research, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0583, USA
Am J Psychiatry 162:1697-705. 2005..Cognitive probes, coupled with neuroimaging, provide an approach toward clarifying the neurophysiology of bipolar disorder... - Effects of co-occurring cannabis use disorders on the course of bipolar disorder after a first hospitalization for maniaStephen M Strakowski
Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, 2341 Albert Sabin Way, Cincinnati, OH 45267, USA
Arch Gen Psychiatry 64:57-64. 2007..Cannabis use disorders commonly co-occur in bipolar disorder; however, the effects of cannabis abuse on outcome have been minimally studied... - Quality of life during treatment with haloperidol or olanzapine in the year following a first psychotic episodeStephen M Strakowski
Center for Imaging Research and Division of Bipolar Disorders Research, University of Cincinnati College of Medicine, 231 Albert Sabin Way ML0583, Cincinnati, OH 45267 0583, USA
Schizophr Res 78:161-9. 2005..This improvement is particularly relevant early in the course of schizophrenia... - Neuroanatomical characterization of child offspring of bipolar parentsManpreet K Singh
Department of Psychiatry, Division of Bipolar Disorders Research, University of Cincinnati, OH 45267 0559, USA
J Am Acad Child Adolesc Psychiatry 47:526-31. 2008..We hypothesized that at-risk (AR) children would exhibit abnormalities in brain regions that are involved in mood regulation... - Proton magnetic resonance spectroscopy of the frontal lobe and cerebellar vermis in children with a mood disorder and a familial risk for bipolar disordersKim M Cecil
Imaging Research Center, Department of Radiology, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
J Child Adolesc Psychopharmacol 13:545-55. 2003.... - Ethnicity and diagnosis in patients with affective disordersStephen M Strakowski
Bipolar and Psychotic Disorders Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA
J Clin Psychiatry 64:747-54. 2003..However, it may be due to a perception that psychotic symptoms are more chronic or persistent than affective symptoms in these patients... - The efficacy and tolerability of quetiapine versus divalproex for the treatment of impulsivity and reactive aggression in adolescents with co-occurring bipolar disorder and disruptive behavior disorder(s)Drew H Barzman
Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati, Cincinnati, Ohio, USA
J Child Adolesc Psychopharmacol 16:665-70. 2006..The aim of this study was to compare the efficacy and tolerability of quetiapine and divalproex for the treatment of impulsivity and reactive aggression in adolescents with co-occurring bipolar disorder and disruptive behavior disorders... - Psychopathology in children of bipolar parentsManpreet K Singh
Division of Bipolar Disorders Research, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA
J Affect Disord 102:131-6. 2007..Few studies have examined the psychopathological profiles of child offspring of bipolar parents. Such investigations are useful as a first step to identifying potential prodromal manifestations of bipolar disorder... - Severity of bipolarity in hospitalized manic adolescents with history of stimulant or antidepressant treatmentCesar A Soutullo
University of Cincinnati, Department of Psychiatry, Biological Psychiatry and Psychotic and Bipolar Disorders Research Programs, PO Box 670559, 231 Bethesda Avenue, Cincinnati, OH 45267 0559, USA
J Affect Disord 70:323-7. 2002..Childhood bipolarity (BP) and ADHD frequently co-occur, these children often receive stimulants... - The effect of multiple doses of cimetidine on the steady-state pharmacokinetics of quetiapine in men with selected psychotic disordersStephen M Strakowski
Bipolar and Psychotic Disorders Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Ohio 45267-0559, USA
J Clin Psychopharmacol 22:201-5. 2002..No serious adverse events were observed during quetiapine treatment. No clinically relevant alterations in quetiapine pharmacokinetics were observed after cimetidine coadministration in patients with psychotic disorders... - Inhibition and attention in adolescents with nonmanic mood disorders and a high risk for developing maniaManpreet K Singh
Department of Psychiatry, Division of Bipolar Disorders Research, University of Cincinnati, Cincinnati, OH, USA
J Clin Exp Neuropsychol 31:1-7. 2009..75), and color naming speed (d = 0.88). The results indicate that MD participants exhibit psychomotor disinhibition, marginal cognitive slowing and cautious response biases, but no formal deficits in sustained or selective attention... - Rates, types, and psychosocial correlates of legal charges in adolescents with newly diagnosed bipolar disorderDrew H Barzman
Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati, OH 45229 3039, USA
Bipolar Disord 9:339-44. 2007..To examine the rates, types, and psychosocial correlates of legal charges in adolescents with newly diagnosed bipolar disorder (BD)... - Health-related quality of life in adolescents with bipolar I disorderJennifer Rademacher
Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267, USA
J Child Adolesc Psychopharmacol 17:97-103. 2007..To examine abnormalities in health-related quality of life (HRQOL) and to determine whether pharmacological intervention with divalproex or quetiapine alters HRQOL abnormalities in bipolar adolescents... - A retrospective chart review of intramuscular ziprasidone for agitation in children and adolescents on psychiatric units: prospective studies are neededDrew H Barzman
Children s Hospital Medical Center, Division of Child and Adolescent Psychiatry, Cincinnati, Ohio 45229 3039, USA
J Child Adolesc Psychopharmacol 17:503-9. 2007..Our secondary objective was to examine demographic and clinical factors associated with treatment response... - Frontal lobe differences in bipolar disorder as determined by proton MR spectroscopyKim M Cecil
Imaging Research Center, Department of Radiology, Children s Hospital Medical Center, Cincinnati, OH 45229, USA
Bipolar Disord 4:357-65. 2002..Patients with bipolar disorder having a manic or mixed episode were hypothesized to demonstrate metabolic abnormalities within the frontal lobe... - Meta-analysis of amygdala volumes in children and adolescents with bipolar disorderJonathan C Pfeifer
Department of Psychiatry, Cincinnati Children s Hospital Medical Center, Cincinnati, OH, USA
J Am Acad Child Adolesc Psychiatry 47:1289-98. 2008..Therefore, we conducted a meta-analysis summarizing the literature examining amygdala size obtained from magnetic resonance imaging in bipolar youths and adults... - Cerebellar ataxia in youths at risk for bipolar disorderLisa L Giles
Division of Bipolar Disorders Research, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
Bipolar Disord 10:733-7. 2008..The present study examined cerebellar function in youths who were at familial risk for BD by comparing ataxia battery scores of youths with a bipolar parent to those of healthy youths... - Adjunctive topiramate in hospitalized children and adolescents with bipolar disordersDrew H Barzman
Cincinnati Children s Hospital Medical Center, Division of Child and Adolescent Psychiatry, and Department of Psychiatry, University of Cincinnati College of Medicine, Ohio 45267, USA
J Child Adolesc Psychopharmacol 15:931-7. 2005..The aim of this study was to assess topiramate as adjunctive treatment in children and adolescents hospitalized with bipolar disorders... - Establishing the neurobiologic basis of treatment in children and adolescents with generalized anxiety disorderJeffrey R Strawn
Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati, College of Medicine, Cincinnati, Ohio 45267 0559, USA
Depress Anxiety 29:328-39. 2012..These findings also raise the possibility that functional activity within the amygdala and VLPFC may be altered following successful treatment... - Neuroanatomic comparison of bipolar adolescents with and without cannabis use disordersKelly Jarvis
University of Cincinnati, Division of Bipolar Disorders Research, Department of Psychiatry, Cincinnati, OH 45267 0559, USA
J Child Adolesc Psychopharmacol 18:557-63. 2008..In this pilot study, we compared brain morphometry between bipolar adolescents with co-occurring cannabis use disorders (CUD) and bipolar adolescents without any substance use disorder... - Lithium treatment effects on Myo-inositol in adolescents with bipolar depressionNick C Patel
Division of Bipolar Disorders Research, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0004, USA
Biol Psychiatry 60:998-1004. 2006..This study used proton magnetic resonance spectroscopy (1H MRS) to identify the in vivo effects of lithium on myo-inositol (mI) concentrations in adolescent bipolar depression... - Dopamine and serotonin receptor binding and antipsychotic efficacyNeil M Richtand
Psychiatry Service, Cincinnati Veterans Affairs Medical Center, Cincinnati, OH, USA
Neuropsychopharmacology 32:1715-26. 2007..2) Increasing 5-HT(2C) and 5-HT(2A) receptor-binding affinities also facilitate antipsychotic efficacy. (3) Increasing 5-HT(1A) receptor-binding affinity, in contrast, reduces antipsychotic efficacy... - Voxel-based study of structural changes in first-episode patients with bipolar disorderCaleb M Adler
Division of Bipolar Disorders Research, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267, USA
Biol Psychiatry 61:776-81. 2007..In this study, we used VBM to explore structural brain changes in first-episode bipolar patients... - Twelve-month outcome of adolescents with bipolar disorder following first hospitalization for a manic or mixed episodeMelissa P DelBello
Division of Bipolar Disorders Research, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
Am J Psychiatry 164:582-90. 2007..The aim of this study was to examine the 12-month outcome of bipolar adolescents following an initial hospitalization for a manic or mixed episode... - Response and remission in adolescent mania: signal detection analyses of the young mania rating scaleNick C Patel
Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0004, USA
J Am Acad Child Adolesc Psychiatry 46:628-35. 2007..The purpose of this study was to determine optimal criteria for defining response and remission in adolescents with acute mania... - A 12-week single-blind trial of quetiapine for the treatment of mood symptoms in adolescents at high risk for developing bipolar I disorderMelissa P DelBello
Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0559, USA
J Clin Psychiatry 68:789-95. 2007..To investigate the effectiveness and tolerability of quetiapine for the treatment of adolescents at high risk for developing bipolar I disorder... - Temperament in child offspring of parents with bipolar disorderManpreet K Singh
Department of Psychiatry, Division of Bipolar Disorders Research, University of Cincinnati, Cincinnati, Ohio 45267 0559, USA
J Child Adolesc Psychopharmacol 18:589-93. 2008..The aim of this study was to examine the relationship between temperament and psychopathology in child offspring of parents with bipolar disorder... - Cigarette smoking in the early course of bipolar disorder: association with ages-at-onset of alcohol and marijuana useJaimee L Heffner
Tri State Tobacco and Alcohol Research Center, University of Cincinnati Genome Research Institute, Cincinnati, OH 45237, USA
Bipolar Disord 10:838-45. 2008..e., three or more times per week for a month or more)... - Body mass indexes and lipid profiles in hospitalized children and adolescents exposed to atypical antipsychoticsNick C Patel
Division of Bipolar Disorders Research, University of Cincinnati College of Medicine, and Department of Psychiatry, Cincinnati Children s Hospital Medical Center, Ohio 45267 0004, USA
J Child Adolesc Psychopharmacol 17:303-11. 2007..The purpose of this study was to examine body mass indexes (BMI) and lipid profiles of children and adolescents hospitalized for a psychiatric illness and exposed to an atypical antipsychotic... - Docosahexaenoic acid supplementation increases prefrontal cortex activation during sustained attention in healthy boys: a placebo-controlled, dose-ranging, functional magnetic resonance imaging studyRobert K McNamara
Department of Psychiatry, Center for Imaging Research, Division of Bipolar Disorders Research, University of Cincinnati College of Medicine, Cincinnati, OH 45219 0516, USA
Am J Clin Nutr 91:1060-7. 2010..However, the effects of DHA supplementation on functional cortical activity in human subjects are unknown... - Wisconsin Card Sorting Test performance in bipolar disorder: effects of mood state and early courseDavid E Fleck
Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0559, USA
Bipolar Disord 10:539-45. 2008..However, it is unclear to what extent executive dysfunction exists (i) during syndromal remission, when mood symptoms are attenuated, and (ii) during the early course of bipolar disorder... - Parental reports of executive dysfunction in adolescents with bipolar disorderPaula K Shear
Department of Psychology, University of Cincinnati, OH 45221, USA
Child Neuropsychol 8:285-95. 2002..The findings suggest that adolescents with BPD have functional deficits on tasks requiring executive functioning skills that are not explicable solely on the basis of comorbid ADHD... - Concurrent tracking of alcohol use and bipolar disorder symptomsDavid E Fleck
Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
Bipolar Disord 8:338-44. 2006..The primary aim of this analysis was to examine concurrent symptom tracking and how the relative onsets of AUD and BD influence the concurrent tracking of symptoms... - Obstetrical complications in children at high risk for bipolar disorderManpreet K Singh
Center for Bipolar Disorders Research, University of Cincinnati College of Medicine, and Cincinnati Children s Hospital Medical Center, Division of Child and Adolescent Psychiatry, Cincinnati, OH 45267 0559, United States
J Psychiatr Res 41:680-5. 2007..Additionally, within this "at-risk" (AR) sample, we hypothesized that obstetrical complications would be associated with the development of psychiatric disorders... - Neuroanatomic characterization of schizoaffective disorder using MRI: a pilot studyGlen E Getz
Bipolar and Psychotic Disorders Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
Schizophr Res 55:55-9. 2002..Patients diagnosed with SCA exhibited regional abnormalities on the striatum that resemble those seen in BPD. This study suggests that SCA has some neuroanatomical characteristics similar to BPD... - Abnormal frontal white matter tracts in bipolar disorder: a diffusion tensor imaging studyCaleb M Adler
Bipolar and Psychotic Disorders Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, OH 45267 0559, USA
Bipolar Disord 6:197-203. 2004..In this study we utilized diffusion tensor imaging (DTI) to examine prefrontal white matter in patients with bipolar disorder... - Sex, ethnicity, and antipsychotic medication use in patients with psychosisLesley M Arnold
Bipolar and Psychotic Disorders Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, 231 Albert Sabin Way, Cincinnati, OH 45267 0559, USA
Schizophr Res 66:169-75. 2004..There were no ethnic or sex differences in the dosing of antipsychotics for the treatment of schizophrenia spectrum disorders. There were also no ethnic or sex differences in the use of second-generation antipsychotics... - Magnetic resonance imaging analysis of amygdala and other subcortical brain regions in adolescents with bipolar disorderMelissa P DelBello
Bipolar and Psychotic Disorders Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA
Bipolar Disord 6:43-52. 2004..We hypothesized that adolescents with bipolar disorder would exhibit abnormalities in brain regions that are involved in the regulation of mood including the amygdala, globus pallidus, caudate, putamen, and thalamus... - Verbal memory in mania: effects of clinical state and task requirementsDavid E Fleck
Bipolar and Psychotic Disorders Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
Bipolar Disord 5:375-80. 2003..Manic patients exhibit impaired verbal learning and memory, particularly following longstanding illness. However, it is unclear whether recognition and recall performance are differentially influenced by a manic mood state... - Rates and predictors of developing a manic or hypomanic episode 1 to 2 years following a first hospitalization for major depression with psychotic featuresMelissa P DelBello
The Bipolar and Psychotic Disorders Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0559, USA
J Child Adolesc Psychopharmacol 13:173-85. 2003.... - Atypical antipsychotics in the treatment of bipolar disorderStephen M Strakowski
Department of Psychiatry, University of Cincinnati College of Medicine, PO Box 670559, Cincinnati, OH 45267 0559, USA
Expert Opin Pharmacother 4:751-60. 2003..Atypical antipsychotics offer different side effect profiles than older antipsychotics, which may be of benefit for some patients. Consequently, atypical antipsychotics provide an important treatment option for bipolar patients... - Adjunctive topiramate treatment for pediatric bipolar disorder: a retrospective chart reviewMelissa P DelBello
Bipolar and Psychiatric Disorders Research Program, Department of Psychiatry, University of Cincinnati, College of Medicine, Cincinnati, Ohio 45267, USA
J Child Adolesc Psychopharmacol 12:323-30. 2002..The objective of this study was to evaluate the effectiveness, safety, and tolerability of the anticonvulsant agent, topiramate, as adjunctive treatment for children and adolescents with bipolar disorders... - Ventricular and periventricular structural volumes in first- versus multiple-episode bipolar disorderStephen M Strakowski
Bipolar and Psychotic Disorders Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
Am J Psychiatry 159:1841-7. 2002..In addition, it is unknown whether ventriculomegaly in bipolar disorder reflects acquired volume loss or underdevelopment of periventricular structures... - A double-blind, randomized, placebo-controlled study of quetiapine as adjunctive treatment for adolescent maniaMelissa P DelBello
Bipolar and Psychotic Disorders Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
J Am Acad Child Adolesc Psychiatry 41:1216-23. 2002..It was hypothesized that DVP in combination with quetiapine would be more effective than DVP alone for treating mania associated with adolescent bipolar disorder. Furthermore, it was hypothesized that quetiapine would be well tolerated... - Volumetric MRI studies of mood disorders: do they distinguish unipolar and bipolar disorder?Stephen M Strakowski
Department of Psychiatry, University of Cincinnati College of Medicine, OH 45267 0559, USA
Bipolar Disord 4:80-8. 2002..This hypothesis remains speculative as much more research is needed to specifically examine how morphometric brain abnormalities translate into the neurophysiologic deficits that produce mood disorders... - Changes in neuronal activation in patients with bipolar disorder during performance of a working memory taskCaleb M Adler
Bipolar and Psychotic Disorders Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
Bipolar Disord 6:540-9. 2004..We hypothesized that patients with bipolar disorder would demonstrate changes in neuronal activation in specific regions forming part of the working memory network... - Processing efficiency and sustained attention in bipolar disorderDavid E Fleck
Center for Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
J Int Neuropsychol Soc 11:49-57. 2005..Problems with processing efficiency are viewed as trait characteristics of bipolar disorder that may be overlooked by traditional error-based assessments... - Comorbid ADHD is associated with altered patterns of neuronal activation in adolescents with bipolar disorder performing a simple attention taskCaleb M Adler
Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA
Bipolar Disord 7:577-88. 2005..In this study we utilized functional magnetic resonance imaging (fMRI) to compare activation patterns during performance of a simple attention task between bipolar adolescents with and without ADHD... - Phenomenology associated with age at onset in patients with bipolar disorder at their first psychiatric hospitalizationNick C Patel
College of Pharmacy, University of Cincinnati, Cincinnati, OH 45267 0004, USA
Bipolar Disord 8:91-4. 2006..To compare the clinical presentation of patients with early-onset (age <18 years) and typical-onset (age 20-30 years) bipolar disorder at the time of first hospitalization... - Ethnic differences in maintenance antipsychotic prescription among adolescents with bipolar disorderNick C Patel
Department of Psychiatry, University of Cincinnati, and the General Clinical Research Center and Mental Health Service Line, Cincinnati Veterans Affairs Medical Center, Ohio 45267 0004, USA
J Child Adolesc Psychopharmacol 15:938-46. 2005..The aim of this study was to compare the longitudinal use of psychotropic medications in African-American and Caucasian adolescents with a diagnosis of bipolar disorder following their first psychiatric hospitalization... - Ethnic differences in symptom presentation of youths with bipolar disorderNick C Patel
The College of Pharmacy, University of Cincinnati, OH 45267 0004, USA
Bipolar Disord 8:95-9. 2006..To compare symptom profiles of African-American and white adolescents with a diagnosis of bipolar disorder... - Processing efficiency and directed forgetting in bipolar disorderDavid E Fleck
Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0559, USA
J Int Neuropsychol Soc 11:871-80. 2005..Problems with processing efficiency are viewed as trait characteristics of bipolar disorder that may be overlooked by traditional error-based assessments... - Open-label lithium for the treatment of adolescents with bipolar depressionNick C Patel
College of Pharmacy and Department of Psychiatry, University of Cincinnati, OH 45267 0004, USA
J Am Acad Child Adolesc Psychiatry 45:289-97. 2006..We hypothesized that patients receiving open-label treatment with lithium during a 6-week period would experience a statistically and clinically significant decrease in depressive symptoms and tolerate lithium treatment fairly well... - The neurophysiology of childhood and adolescent bipolar disorderMelissa P DelBello
Division of Bipolar Disorder Research, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
CNS Spectr 11:298-311. 2006.... - MRI analysis of cerebellar vermal abnormalities in bipolar disorderNeil P Mills
Center for Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
Am J Psychiatry 162:1530-2. 2005..The authors sought to expand previous findings of vermal abnormalities in bipolar disorder patients... - Working memory and inhibitory control among manic and euthymic patients with bipolar disorderEric R Larson
Center for Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati School of Medicine, Cincinnati, Ohio, USA
J Int Neuropsychol Soc 11:163-72. 2005..These results indicated that patients in the present sample had relatively normal working memory abilities, but had a deficit in behavioral self-regulation, which was evident across mood states... - Brain network dysfunction in bipolar disorderCaleb M Adler
Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
CNS Spectr 11:312-20; quiz 323-4. 2006..As neuroimaging techniques continue to improve, the underlying neural basis of bipolar disorder will be clarified... - Neurochemical alteration in the caudate: implications for the pathophysiology of bipolar disorderNasrin Shahana
Division of Bipolar Disorders Research, Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, OH 45267, United States
Psychiatry Res 193:107-12. 2011..While speculative, these results suggest that AAP do not cause oxidative injury to neuronal membranes... - Parametric neurocognitive task design: a pilot study of sustained attention in adolescents with bipolar disorderMelissa P DelBello
Department of Psychiatry, University of Cincinnati College of Medicine, 231 Bethesda Ave, P O Box 670559, Cincinnati, OH 45267 0559, USA
J Affect Disord 82:S79-88. 2004..Additionally, we hypothesized that the groups would exhibit a similar decline in task performance as level of task difficulty increased and that within each level of task difficulty there would be similar performance among groups... - The McLean-Harvard First-Episode Mania Study: prediction of recovery and first recurrenceMauricio Tohen
Lilly Research Laboratories, Brougher Building, 525 South Meridian, Indianapolis, IN 46225, USA
Am J Psychiatry 160:2099-107. 2003..Since improved prediction of illness course early in bipolar disorder is required to guide treatment planning, the authors evaluated recovery, first recurrence, and new illness onset following first hospitalization for mania... - Ethnicity and first-rank symptoms in patients with psychosisLesley M Arnold
Bipolar and Psychotic Disorders Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
Schizophr Res 67:207-12. 2004..These findings indicate that psychotic symptom presentation should be evaluated in the context of other symptoms (e.g., affective symptoms) in diagnostic assessments in order to prevent misdiagnoses of schizophrenia... - Selective attention in schizoaffective disorder: pilot dataDavid E Fleck
Schizophr Res 68:109-10. 2004 - First episode schizophrenia-related psychosis and substance use disorders: acute response to olanzapine and haloperidolAlan I Green
Commonwealth Research Center and the Massachusetts Mental Health Center, Harvard Medical School, 74 Fenwood Road, Boston, MA 02115, USA
Schizophr Res 66:125-35. 2004..We report on rates of co-occurring substance use disorders in patients within their first episode of schizophrenia-related psychosis from a multicenter, international treatment trial of olanzapine vs. haloperidol... - Course and predictors of weight gain in people with first-episode psychosis treated with olanzapine or haloperidolRobert B Zipursky
Schizophrenia Programme, Centre for Addiction and Mental Health, 250 College Street, Toronto, Ontario, Canada M5T 1R8
Br J Psychiatry 187:537-43. 2005..Substantial weight gain is common with many atypical antipsychotics... - Temporal change in N-acetyl-aspartate concentrations in adolescents with bipolar depression treated with lithiumNick C Patel
College of Pharmacy, University of Georgia, Medical College of Georgia, Augusta, Georgia 30912 2450, USA
J Child Adolesc Psychopharmacol 18:132-9. 2008..This proton magnetic resonance spectroscopy (1H MRS) study identified the in vivo effects of lithium on N-acetyl-aspartate (NAA) concentrations in adolescent bipolar depression... - Hyperthermia and rhabdomyolysis in an adolescent treated with topiramate and olanzapineJeffrey R Strawn
J Child Adolesc Psychopharmacol 18:116-8. 2008 - Memantine normalizes brain activity in the inferior frontal gyrus: a controlled pilot fMRI studyMichael A Cerullo
Schizophr Res 97:294-6. 2007 - Anterior cingulate subregion volumes and executive function in bipolar disorderMolly E Zimmerman
Department of Psychiatry and Human Behavior, Brown Medical School, Providence, RI 02912, USA
Bipolar Disord 8:281-8. 2006....
Research Grants
- Impulsivity as a Core Trait of Bipolar DisorderStephen Strakowski; Fiscal Year: 2007....
- Ethnicity and the Diagnosis of Affective IllnessStephen Strakowski; Fiscal Year: 2007..The final objective is to determine whether Latinos are at risk for similar problems in diagnostic assessments and treatment assignment. ..
- U of Cincinnati Bipolar Disorder Imaging & Treatment Research Center (BITREC)Stephen Strakowski; Fiscal Year: 2007....
- Anterior limbic network dysfunction in bipolar disorderStephen Strakowski; Fiscal Year: 2007..Finally, this work will provide a neurophysiologic substrate to inform additional investigations aimed at identify mechanisms underlying anterior limbic dysfunction both in human and animal models. ..
- SUBSTANCE ABUSE IN FIRST EPISODE MANIAStephen Strakowski; Fiscal Year: 2003..The results of this study could have immediate impact on how treatment of this patient population is developed. ..