Zuzana Strakova

Summary

Affiliation: University of Illinois at Chicago
Country: USA

Publications

  1. pmc Human transcriptional coactivator with PDZ-binding motif (TAZ) is downregulated during decidualization
    Zuzana Strakova
    Department of Obstetrics and Gynecology, University of Illinois at Chicago, IL 60612, USA
    Biol Reprod 82:1112-8. 2010
  2. ncbi request reprint In vivo infusion of interleukin-1beta and chorionic gonadotropin induces endometrial changes that mimic early pregnancy events in the baboon
    Zuzana Strakova
    Department of Obstetrics and Gynecology, University of Illinois, 820 South Wood Street M C 808, Chicago, Illinois 60612 7313, USA
    Endocrinology 146:4097-104. 2005
  3. pmc Multipotent properties of myofibroblast cells derived from human placenta
    Zuzana Strakova
    Department of Obstetrics and Gynecology, University of Illinois at Chicago, Chicago, IL 60612 7313, USA
    Cell Tissue Res 332:479-88. 2008
  4. ncbi request reprint Inhibition of matrix metalloproteinases prevents the synthesis of insulin-like growth factor binding protein-1 during decidualization in the baboon
    Zuzana Strakova
    Department of Obstetrics and Gynecology, University of Illinois at Chicago, Chicago, Illinois 60612 7313, USA
    Endocrinology 144:5339-46. 2003
  5. ncbi request reprint IL-1beta during in vitro decidualization in primate
    Z Strakova
    Department of Obstetrics and Gynecology, The University of Illinois at Chicago, 820 South Wood Street M C 808, Chicago, IL 60612 7313, USA
    J Reprod Immunol 55:35-47. 2002
  6. ncbi request reprint Human chorionic gonadotropin and decidualization in vitro inhibits cytochalasin-D-induced apoptosis in cultured endometrial stromal fibroblasts
    Anna Jasinska
    Department of Obstetrics and Gynecology, University of Illinois, 820 South Wood Street, M C 808, Chicago, Illinois 60612 7313, USA
    Endocrinology 147:4112-21. 2006
  7. ncbi request reprint Increased phosphorylation of myosin light chain prevents in vitro decidualization
    Ivanna Ihnatovych
    Department of Obstetrics and Gynecology, The University of Illinois at Chicago, 820 South Wood Street M C 808, Chicago, Illinois 60612 7313, USA
    Endocrinology 148:3176-84. 2007
  8. ncbi request reprint Decidualization regulates the expression of the endometrial chorionic gonadotropin receptor in the primate
    Paula Cameo
    Department of Obstetrics and Gynecology, University of Illinois at Chicago, Chicago, Illinois 60212 7313, USA
    Biol Reprod 75:681-9. 2006
  9. pmc Manipulating actin dynamics affects human in vitro decidualization
    Ivanna Ihnatovych
    Department of Obstetrics and Gynecology, University of Illinois at Chicago, Chicago, Illinois 60612 7313, USA
    Biol Reprod 81:222-30. 2009
  10. ncbi request reprint Endometrial function: cell specific changes in the uterine environment
    Asgerally T Fazleabas
    Department of Obstetrics and Gynecology, The University of Illinois at Chicago, 820 South Wood Street M C 808, Chicago, IL 60612 7313, USA
    Mol Cell Endocrinol 186:143-7. 2002

Research Grants

  1. REGULATION OF CELL DIFFERENTATION DURING DECIDUALIZATION
    Zuzana Strakova; Fiscal Year: 2002
  2. Cell differentiation during decidualization
    Zuzana Strakova; Fiscal Year: 2005
  3. Cell differentiation during decidualization
    Zuzana Strakova; Fiscal Year: 2006
  4. Cell differentiation during decidualization
    Zuzana Strakova; Fiscal Year: 2007
  5. Cell Differentation During Decidualization
    Zuzana Strakova; Fiscal Year: 2009
  6. Cell Differentation During Decidualization
    Zuzana Strakova; Fiscal Year: 2010

Collaborators

Detail Information

Publications18

  1. pmc Human transcriptional coactivator with PDZ-binding motif (TAZ) is downregulated during decidualization
    Zuzana Strakova
    Department of Obstetrics and Gynecology, University of Illinois at Chicago, IL 60612, USA
    Biol Reprod 82:1112-8. 2010
    ....
  2. ncbi request reprint In vivo infusion of interleukin-1beta and chorionic gonadotropin induces endometrial changes that mimic early pregnancy events in the baboon
    Zuzana Strakova
    Department of Obstetrics and Gynecology, University of Illinois, 820 South Wood Street M C 808, Chicago, Illinois 60612 7313, USA
    Endocrinology 146:4097-104. 2005
    ..These changes suggest that infusion of IL-1beta at the time of implantation into the nonpregnant baboon treated with hCG synergizes with hCG and mimics the early endometrial events associated with the presence of an embryo...
  3. pmc Multipotent properties of myofibroblast cells derived from human placenta
    Zuzana Strakova
    Department of Obstetrics and Gynecology, University of Illinois at Chicago, Chicago, IL 60612 7313, USA
    Cell Tissue Res 332:479-88. 2008
    ....
  4. ncbi request reprint Inhibition of matrix metalloproteinases prevents the synthesis of insulin-like growth factor binding protein-1 during decidualization in the baboon
    Zuzana Strakova
    Department of Obstetrics and Gynecology, University of Illinois at Chicago, Chicago, Illinois 60612 7313, USA
    Endocrinology 144:5339-46. 2003
    ..Disruption of actin filaments enhances IGFBP-1 induction. Thus, our data imply that IL-1beta-induced MMPs and particularly MMP-3 may up-regulate IGFBP-1 by disrupting the actin cytoskeleton as a result of ECM degradation...
  5. ncbi request reprint IL-1beta during in vitro decidualization in primate
    Z Strakova
    Department of Obstetrics and Gynecology, The University of Illinois at Chicago, 820 South Wood Street M C 808, Chicago, IL 60612 7313, USA
    J Reprod Immunol 55:35-47. 2002
    ..Inhibition of IL-1beta induced pathways leads to reduction of IGFBP-1 expression, suggesting that IL-1beta may be involved in the events leading to decidualization in baboons...
  6. ncbi request reprint Human chorionic gonadotropin and decidualization in vitro inhibits cytochalasin-D-induced apoptosis in cultured endometrial stromal fibroblasts
    Anna Jasinska
    Department of Obstetrics and Gynecology, University of Illinois, 820 South Wood Street, M C 808, Chicago, Illinois 60612 7313, USA
    Endocrinology 147:4112-21. 2006
    ..Furthermore, this inhibition of apoptosis may be mediated in part by IGFBP-1 and prolactin and the alteration in the expression of Bcl-2 and Bax...
  7. ncbi request reprint Increased phosphorylation of myosin light chain prevents in vitro decidualization
    Ivanna Ihnatovych
    Department of Obstetrics and Gynecology, The University of Illinois at Chicago, 820 South Wood Street M C 808, Chicago, Illinois 60612 7313, USA
    Endocrinology 148:3176-84. 2007
    ..These data provide evidence that the regulation of cytoskeletal dynamics by MLC20 phosphorylation is critical for decidualization...
  8. ncbi request reprint Decidualization regulates the expression of the endometrial chorionic gonadotropin receptor in the primate
    Paula Cameo
    Department of Obstetrics and Gynecology, University of Illinois at Chicago, Chicago, Illinois 60212 7313, USA
    Biol Reprod 75:681-9. 2006
    ..This inhibition of LHCGR expression also coincides with the decrease of measurable CG in peripheral circulation...
  9. pmc Manipulating actin dynamics affects human in vitro decidualization
    Ivanna Ihnatovych
    Department of Obstetrics and Gynecology, University of Illinois at Chicago, Chicago, Illinois 60612 7313, USA
    Biol Reprod 81:222-30. 2009
    ....
  10. ncbi request reprint Endometrial function: cell specific changes in the uterine environment
    Asgerally T Fazleabas
    Department of Obstetrics and Gynecology, The University of Illinois at Chicago, 820 South Wood Street M C 808, Chicago, IL 60612 7313, USA
    Mol Cell Endocrinol 186:143-7. 2002
    ..We suggest that these changes are critical to ensure prolonged maintenance of endometrial function during gestation and facilitate trophoblast invasion...
  11. pmc Chorionic gonadotropin and uterine dialogue in the primate
    Paula Cameo
    Department of Obstetrics and Gynecology, University of Illinois at Chicago, Chicago, IL, USA
    Reprod Biol Endocrinol 2:50. 2004
    ....
  12. pmc Cofilin and slingshot localization in the epithelium of uterine endometrium changes during the menstrual cycle and in endometriosis
    Kirsten Morris
    Department of Obstetrics and Gynecology, University of Illinois at Chicago, Chicago, IL 60612, USA
    Reprod Sci 18:1014-24. 2011
    ..We suggest that cofilin-mediated actin reorganization in uterine epithelial cells might be important in preparation for blastocyst implantation; dysregulation of this reorganization may lead to decreased fertility in endometriosis...
  13. ncbi request reprint Signal transduction pathways activated by chorionic gonadotropin in the primate endometrial epithelial cells
    Santha Srisuparp
    Department of Obstetrics and Gynecology, University of Illinois at Chicago, Chicago, Illinois 60212 7313, USA
    Biol Reprod 68:457-64. 2003
    ....
  14. pmc Chorionic gonadotropin regulates prostaglandin E synthase via a phosphatidylinositol 3-kinase-extracellular regulatory kinase pathway in a human endometrial epithelial cell line: implications for endometrial responses for embryo implantation
    Prajna Banerjee
    Department of Physiology and Biophysics, University of Illinois, Chicago, Illinois 60612, USA
    Endocrinology 150:4326-37. 2009
    ..We suggest that this alternative PI3K-ERK-Elk pathway activated by CG regulates prostaglandin production by the endometrial epithelium and serves as an early trigger to prepare the endometrium for implantation...
  15. ncbi request reprint Implantation: embryonic signals and the modulation of the uterine environment--a review
    A T Fazleabas
    Department of Obstetrics and Gynecology, University of Illinois at Chicago, 820 South Wood Street, Chicago, IL 60612 7313, USA
    Placenta 25:S26-31. 2004
    ....
  16. pmc Soluble amyloid precursor protein: a novel proliferation factor of adult progenitor cells of ectodermal and mesodermal origin
    Michael P Demars
    Department of Anatomy and Cell Biology, The University of Illinois at Chicago, 808 S Wood St, RM, 572 Chicago, IL 60612, USA
    Stem Cell Res Ther 2:36. 2011
    ..While a previous study implicates sAPPĪ± in the regulation of neural progenitor cell proliferation in the subventricular zone of adult mice, the ubiquitous expression of APP suggests that its role as a growth factor might be broader...
  17. ncbi request reprint Implantation in the baboon
    A T Fazleabas
    Department of Obstetrics and Gynecology, University of Illinois at Chicago, Chicago, IL, USA
    Gynecol Obstet Invest 57:30-1. 2004
  18. ncbi request reprint The role of chorionic gonadotropin (CG) in blastocyst implantation
    S Srisuparp
    Department of Obstetrics and Gynecology, University of Illinois at Chicago, Chicago, IL 60612-7313, USA
    Arch Med Res 32:627-34. 2001
    ..Thus, our results suggest that CG plays an important role in implantation in addition to its luteotrophic role...

Research Grants7

  1. REGULATION OF CELL DIFFERENTATION DURING DECIDUALIZATION
    Zuzana Strakova; Fiscal Year: 2002
    ..We anticipate that our ongoing studies will contribute to find therapies to treat endometrial dysfunctions associated with infertility, habitual abortions and/or insufficient placental development. ..
  2. Cell differentiation during decidualization
    Zuzana Strakova; Fiscal Year: 2005
    ..These may include endometrial dysfunction associated with infertility, pregnancy failures in patients with luteal phase defects, habitual abortions and/or insufficient placental development. ..
  3. Cell differentiation during decidualization
    Zuzana Strakova; Fiscal Year: 2006
    ..These may include endometrial dysfunction associated with infertility, pregnancy failures in patients with luteal phase defects, habitual abortions and/or insufficient placental development. ..
  4. Cell differentiation during decidualization
    Zuzana Strakova; Fiscal Year: 2007
    ..These may include endometrial dysfunction associated with infertility, pregnancy failures in patients with luteal phase defects, habitual abortions and/or insufficient placental development. ..
  5. Cell Differentation During Decidualization
    Zuzana Strakova; Fiscal Year: 2009
    ..Thus, in the long term our studies might provide new targets of intervention leading to improvements in diagnosis and treatment. ..
  6. Cell Differentation During Decidualization
    Zuzana Strakova; Fiscal Year: 2010
    ..Thus, in the long term our studies might provide new targets of intervention leading to improvements in diagnosis and treatment. ..