Arlin Stoltzfus

Summary

Affiliation: University of Maryland
Country: USA

Publications

  1. doi request reprint Climbing mount probable: mutation as a cause of nonrandomness in evolution
    Arlin Stoltzfus
    Center for Advanced Research in Biotechnology, Rockville, MD 20850, USA
    J Hered 100:637-47. 2009
  2. ncbi request reprint Mutationism and the dual causation of evolutionary change
    Arlin Stoltzfus
    Center for Advanced Research in Biotechnology, Rockville, MD 20850, USA
    Evol Dev 8:304-17. 2006
  3. ncbi request reprint A sequence-based model accounts largely for the relationship of intron positions to protein structural features
    Danny W De Kee
    Center for Advanced Research in Biotechnology, Rockville, MD, USA
    Mol Biol Evol 24:2158-68. 2007
  4. doi request reprint Evidence for a predominant role of oxidative damage in germline mutation in mammals
    Arlin Stoltzfus
    Center for Advanced Research in Biotechnology, 9600 Gudelsky Drive, Rockville, MD 20850, United States
    Mutat Res 644:71-3. 2008
  5. ncbi request reprint Mutation-biased adaptation in a protein NK model
    Arlin Stoltzfus
    Center for Advanced Research in Biotechnology, University of Maryland Biotechnology Institute, Gaithersburg, Maryland, USA
    Mol Biol Evol 23:1852-62. 2006
  6. pmc Bio::NEXUS: a Perl API for the NEXUS format for comparative biological data
    Thomas Hladish
    Center for Advanced Research in Biotechnology, Rockville, MD 20850, USA
    BMC Bioinformatics 8:191. 2007
  7. ncbi request reprint Amino acid exchangeability and the adaptive code hypothesis
    Arlin Stoltzfus
    Center for Advanced Research in Biotechnology, 9600 Gudelsky Drive, Rockville, MD 20850, USA
    J Mol Evol 65:456-62. 2007
  8. pmc Constructive neutral evolution: exploring evolutionary theory's curious disconnect
    Arlin Stoltzfus
    Institute for Bioscience and Biotechnology Research, 9600 Gudelsky Drive, Rockville, MD 20850, USA
    Biol Direct 7:35. 2012
  9. ncbi request reprint Molecular evolution: introns fall into place
    Arlin Stoltzfus
    Center for Advanced Research in Biotechnology CARB, 9600 Gudelsky Drive, Rockville, Maryland 20850, USA
    Curr Biol 14:R351-2. 2004
  10. doi request reprint Gene identification in black cohosh (Actaea racemosa L.): expressed sequence tag profiling and genetic screening yields candidate genes for production of bioactive secondary metabolites
    Martin J Spiering
    Fischell Department of Bioengineering, Institute for Bioscience and Biotechnology Research, University of Maryland, Rockville, MD 20850, USA
    Plant Cell Rep 30:613-29. 2011

Research Grants

Collaborators

Detail Information

Publications12

  1. doi request reprint Climbing mount probable: mutation as a cause of nonrandomness in evolution
    Arlin Stoltzfus
    Center for Advanced Research in Biotechnology, Rockville, MD 20850, USA
    J Hered 100:637-47. 2009
    ..To meet this challenge requires developing knowledge of mutation as a biological process, understanding how mutation imposes propensities on evolution, and applying methods of analysis that incorporate mutational effects...
  2. ncbi request reprint Mutationism and the dual causation of evolutionary change
    Arlin Stoltzfus
    Center for Advanced Research in Biotechnology, Rockville, MD 20850, USA
    Evol Dev 8:304-17. 2006
    ....
  3. ncbi request reprint A sequence-based model accounts largely for the relationship of intron positions to protein structural features
    Danny W De Kee
    Center for Advanced Research in Biotechnology, Rockville, MD, USA
    Mol Biol Evol 24:2158-68. 2007
    ..Phase-dependent correlations with secondary structure and side-chain surface accessibility are particularly strong. However, these phase-dependent correlations are explained largely by the sequence-based disruptive model...
  4. doi request reprint Evidence for a predominant role of oxidative damage in germline mutation in mammals
    Arlin Stoltzfus
    Center for Advanced Research in Biotechnology, 9600 Gudelsky Drive, Rockville, MD 20850, United States
    Mutat Res 644:71-3. 2008
    ..Analysis of damage susceptibility holds promise for improving models of mutational specificity...
  5. ncbi request reprint Mutation-biased adaptation in a protein NK model
    Arlin Stoltzfus
    Center for Advanced Research in Biotechnology, University of Maryland Biotechnology Institute, Gaithersburg, Maryland, USA
    Mol Biol Evol 23:1852-62. 2006
    ..Thus, mutational explanations for evolved patterns need not presuppose neutral evolution...
  6. pmc Bio::NEXUS: a Perl API for the NEXUS format for comparative biological data
    Thomas Hladish
    Center for Advanced Research in Biotechnology, Rockville, MD 20850, USA
    BMC Bioinformatics 8:191. 2007
    ..However, due to its complexity, NEXUS is not well supported by software and is not easily accessible to bioinformatics users and developers...
  7. ncbi request reprint Amino acid exchangeability and the adaptive code hypothesis
    Arlin Stoltzfus
    Center for Advanced Research in Biotechnology, 9600 Gudelsky Drive, Rockville, MD 20850, USA
    J Mol Evol 65:456-62. 2007
    ..The results reported here indicate that most of the nonrandomness in the amino acids to codon assignments can be explained by incremental code evolution, with a small residue of orderliness that may reflect code adaptation...
  8. pmc Constructive neutral evolution: exploring evolutionary theory's curious disconnect
    Arlin Stoltzfus
    Institute for Bioscience and Biotechnology Research, 9600 Gudelsky Drive, Rockville, MD 20850, USA
    Biol Direct 7:35. 2012
    ..This view, which now lays claim to important theoretical, experimental, and practical results, demands our attention. CNE provides a way to explore its most significant implications about the role of variation in evolution...
  9. ncbi request reprint Molecular evolution: introns fall into place
    Arlin Stoltzfus
    Center for Advanced Research in Biotechnology CARB, 9600 Gudelsky Drive, Rockville, Maryland 20850, USA
    Curr Biol 14:R351-2. 2004
    ..The evolutionary origin of spliceosomal introns remains elusive. The startling success of a new way of predicting intron sites suggests that the splicing machinery determines where introns are added to genes...
  10. doi request reprint Gene identification in black cohosh (Actaea racemosa L.): expressed sequence tag profiling and genetic screening yields candidate genes for production of bioactive secondary metabolites
    Martin J Spiering
    Fischell Department of Bioengineering, Institute for Bioscience and Biotechnology Research, University of Maryland, Rockville, MD 20850, USA
    Plant Cell Rep 30:613-29. 2011
    ....
  11. ncbi request reprint The evolutionary gain of spliceosomal introns: sequence and phase preferences
    Wei Gang Qiu
    Center for Advanced Research in Biotechnology, University of Maryland Biotechnology Institute, Rockville, Maryland, USA
    Mol Biol Evol 21:1252-63. 2004
    ..Thus, intron gain accounts for the vast majority of extant introns and for the bias toward phase 0 introns that previously was interpreted as evidence for ancient formative introns...
  12. pmc The exchangeability of amino acids in proteins
    Lev Y Yampolsky
    Department of Biological Sciences, East Tennessee State University, Johnson City, Tennessee 37614 1710, USA
    Genetics 170:1459-72. 2005
    ..EX not only captures useful information on exchangeability while remaining free of other effects, but also outperforms all measures tested except for the best-performing alignment scoring matrix, which is comparable in performance...

Research Grants4

  1. Intron evolution: automated phylogentic analysis system
    Arlin Stoltzfus; Fiscal Year: 2004
    ..abstract_text> ..