Lynn L Stoll

Summary

Affiliation: University of Iowa
Country: USA

Publications

  1. ncbi request reprint Antioxidant effects of statins
    Lynn L Stoll
    Department of Internal Medicine, Division of Cardiovascular Diseases, The University of Iowa, Iowa City, Iowa, USA
    Timely Top Med Cardiovasc Dis 9:E1. 2005
  2. ncbi request reprint Antioxidant effects of statins
    Lynn L Stoll
    Department of Internal Medicine, Division of Cardiovascular Diseases, The University of Iowa, Iowa City, IA 52242, USA
    Drugs Today (Barc) 40:975-90. 2004
  3. ncbi request reprint Potential role of endotoxin as a proinflammatory mediator of atherosclerosis
    Lynn L Stoll
    Department of Internal Medicine, Division of Cardiovascular Diseases, University of Iowa, Iowa City and The VA Medical Center, IA 52242, USA
    Arterioscler Thromb Vasc Biol 24:2227-36. 2004
  4. ncbi request reprint Regulation of endotoxin-induced proinflammatory activation in human coronary artery cells: expression of functional membrane-bound CD14 by human coronary artery smooth muscle cells
    Lynn L Stoll
    Division of Cardiovascular Diseases, Department of Internal Medicine, University of Iowa, Iowa City, IA 52242, USA
    J Immunol 173:1336-43. 2004
  5. ncbi request reprint Low-level endotoxin induces potent inflammatory activation of human blood vessels: inhibition by statins
    James B Rice
    Department of Internal Medicine, University of Iowa College of Medicine, Iowa City, IA 52242, USA
    Arterioscler Thromb Vasc Biol 23:1576-82. 2003
  6. ncbi request reprint Proenkephalin expression and enkephalin release are widely observed in non-neuronal tissues
    Gerene M Denning
    Department of Emergency Medicine, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, C 43 GH, Iowa City, IA 52242 1009, USA
    Peptides 29:83-92. 2008
  7. pmc Surfactant protein D is expressed and modulates inflammatory responses in human coronary artery smooth muscle cells
    Gary D Snyder
    Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, USA
    Am J Physiol Heart Circ Physiol 294:H2053-9. 2008
  8. ncbi request reprint Ghrelin inhibits proinflammatory responses and nuclear factor-kappaB activation in human endothelial cells
    Wei Gen Li
    Department of Internal Medicine, Cardiovascular Division, University of Iowa College of Medicine, Iowa City, IA 52242, USA
    Circulation 109:2221-6. 2004
  9. ncbi request reprint Endotoxin, TLR4 signaling and vascular inflammation: potential therapeutic targets in cardiovascular disease
    Lynn L Stoll
    Dept of Emergency Medicine, 3115 ML, The University of Iowa, Iowa City, IA 52242, USA
    Curr Pharm Des 12:4229-45. 2006
  10. ncbi request reprint Pyocyanin and its precursor phenazine-1-carboxylic acid increase IL-8 and intercellular adhesion molecule-1 expression in human airway epithelial cells by oxidant-dependent mechanisms
    Dwight C Look
    Department of Internal Medicine, University of Iowa Roy J and Lucille A Carver College of Medicine and Iowa City Veterans Affairs Medical Center, Iowa City, IA 52246, USA
    J Immunol 175:4017-23. 2005

Collaborators

Detail Information

Publications15

  1. ncbi request reprint Antioxidant effects of statins
    Lynn L Stoll
    Department of Internal Medicine, Division of Cardiovascular Diseases, The University of Iowa, Iowa City, Iowa, USA
    Timely Top Med Cardiovasc Dis 9:E1. 2005
    ..These antioxidant effects of statins likely contribute to their clinical efficacy in treating cardiovascular disease as well as other chronic conditions associated with increased oxidative stress in humans...
  2. ncbi request reprint Antioxidant effects of statins
    Lynn L Stoll
    Department of Internal Medicine, Division of Cardiovascular Diseases, The University of Iowa, Iowa City, IA 52242, USA
    Drugs Today (Barc) 40:975-90. 2004
    ..These antioxidant effects of statins likely contribute to their clinical efficacy in treating cardiovascular disease as well as other chronic conditions associated with increased oxidative stress in humans...
  3. ncbi request reprint Potential role of endotoxin as a proinflammatory mediator of atherosclerosis
    Lynn L Stoll
    Department of Internal Medicine, Division of Cardiovascular Diseases, University of Iowa, Iowa City and The VA Medical Center, IA 52242, USA
    Arterioscler Thromb Vasc Biol 24:2227-36. 2004
    ..Finally, we discuss species diversity with regard to endotoxin signaling that should be considered when extrapolating experimental data from animal models to humans...
  4. ncbi request reprint Regulation of endotoxin-induced proinflammatory activation in human coronary artery cells: expression of functional membrane-bound CD14 by human coronary artery smooth muscle cells
    Lynn L Stoll
    Division of Cardiovascular Diseases, Department of Internal Medicine, University of Iowa, Iowa City, IA 52242, USA
    J Immunol 173:1336-43. 2004
    ....
  5. ncbi request reprint Low-level endotoxin induces potent inflammatory activation of human blood vessels: inhibition by statins
    James B Rice
    Department of Internal Medicine, University of Iowa College of Medicine, Iowa City, IA 52242, USA
    Arterioscler Thromb Vasc Biol 23:1576-82. 2003
    ..Low-level endotoxemia (ie, >or=50 pg/mL) in apparently healthy subjects was recently identified as a powerful, independent risk factor for atherosclerosis...
  6. ncbi request reprint Proenkephalin expression and enkephalin release are widely observed in non-neuronal tissues
    Gerene M Denning
    Department of Emergency Medicine, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, C 43 GH, Iowa City, IA 52242 1009, USA
    Peptides 29:83-92. 2008
    ..Together our studies indicate that multiple non-neuronal tissues produce PENK and release enkephalins. These data support the hypothesis that non-neuronal tissues could play a role in both local and systemic enkephalin-mediated effects...
  7. pmc Surfactant protein D is expressed and modulates inflammatory responses in human coronary artery smooth muscle cells
    Gary D Snyder
    Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, USA
    Am J Physiol Heart Circ Physiol 294:H2053-9. 2008
    ..In conclusion, SP-D is expressed in human coronary arteries and functions as an anti-inflammatory protein in HCASMCs. SP-D may also participate in the host defense against pathogens that invade the vascular wall...
  8. ncbi request reprint Ghrelin inhibits proinflammatory responses and nuclear factor-kappaB activation in human endothelial cells
    Wei Gen Li
    Department of Internal Medicine, Cardiovascular Division, University of Iowa College of Medicine, Iowa City, IA 52242, USA
    Circulation 109:2221-6. 2004
    ....
  9. ncbi request reprint Endotoxin, TLR4 signaling and vascular inflammation: potential therapeutic targets in cardiovascular disease
    Lynn L Stoll
    Dept of Emergency Medicine, 3115 ML, The University of Iowa, Iowa City, IA 52242, USA
    Curr Pharm Des 12:4229-45. 2006
    ....
  10. ncbi request reprint Pyocyanin and its precursor phenazine-1-carboxylic acid increase IL-8 and intercellular adhesion molecule-1 expression in human airway epithelial cells by oxidant-dependent mechanisms
    Dwight C Look
    Department of Internal Medicine, University of Iowa Roy J and Lucille A Carver College of Medicine and Iowa City Veterans Affairs Medical Center, Iowa City, IA 52246, USA
    J Immunol 175:4017-23. 2005
    ..However, results indicate that the mechanisms by which PCA and pyocyanin exert their effects are not identical, and not all antioxidant interventions are equally effective in inhibiting phenazine-mediated proinflammatory effects...
  11. ncbi request reprint Human coronary endothelial cells convert 14,15-EET to a biologically active chain-shortened epoxide
    Xiang Fang
    Department of Biochemistry, University of Iowa, Iowa City 52242, USA
    Am J Physiol Heart Circ Physiol 283:H2306-14. 2002
    ..These findings implicate beta-oxidation as a major pathway of 14,15-EET metabolism in HCEC and provide the first evidence that EET-derived chain-shortened epoxy fatty acids are biologically active...
  12. pmc CD14 directs adventitial macrophage precursor recruitment: role in early abdominal aortic aneurysm formation
    Andra L Blomkalns
    Division of Cardiovascular Diseases, University of Cincinnati, College of Medicine, Cincinnati, OH 45267 0769, USA
    J Am Heart Assoc 2:e000065. 2013
    ..We hypothesized that CD14 plays a crucial role in adventitial macrophage precursor recruitment early during AAA formation...
  13. ncbi request reprint Peroxisome proliferator-activated receptors: potential therapeutic targets in lung disease?
    Gerene M Denning
    Department of Emergency Medicine, Roy J and Lucille Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA
    Pediatr Pulmonol 41:23-34. 2006
    ..Further studies to understand the contribution of these receptors to health and disease will be important for determining whether they represent a promising target for therapeutic intervention...
  14. ncbi request reprint Exercise enhances myocardial ischemic tolerance via an opioid receptor-dependent mechanism
    Eric W Dickson
    Department of Emergency Medicine, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Iowa City, IA 52242 1009, USA
    Am J Physiol Heart Circ Physiol 294:H402-8. 2008
    ..These findings demonstrate that the acute cardioprotective effects of exercise are mediated, at least in part, through opioid receptor-dependent mechanisms that may include changes in gene expression...
  15. ncbi request reprint Activation of NAD(P)H oxidase by lipid hydroperoxides: mechanism of oxidant-mediated smooth muscle cytotoxicity
    Wei Gen Li
    Department of Internal Medicine, University of Iowa College of Medicine, Iowa City, IA 52242, USA
    Free Radic Biol Med 34:937-46. 2003
    ..These findings suggest that activation of NAD(P)H oxidase, and production of O2*-, play an important role in lipid hydroperoxide-induced smooth muscle cytotoxicity...