Research Topics
| D StickensSummaryAffiliation: University of Texas Southwestern Medical Center Country: USA Publications
| Collaborators |
Detail Information
Publications
EXT genes are differentially expressed in bone and cartilage during mouse embryogenesisD Stickens
McDermott Center for Human Growth and Development, The University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75235 8591, USA
Dev Dyn 218:452-64. 2000..We suggest a model for exostoses formation based on the involvement of EXT1 and EXT2 in the Indian hedgehog/parathyroid hormone-related peptide (PTHrP) signaling pathway, an important regulator of the chondrocyte maturation process...
Isolation and characterization of the murine homolog of the human EXT2 multiple exostoses geneD Stickens
McDermott Center for Human Growth and Development, University of Texas Southwestern Medical Center at Dallas 75235 8591, USA
Biochem Mol Med 61:16-21. 1997..The identification of the mouse EXT2 gene will allow functional analysis through insertional inactivation and reverse genetics in mice in order to better understand the formation of exostoses during bone formation...
The EXT2 multiple exostoses gene defines a family of putative tumour suppressor genesD Stickens
McDermott Center for Human Growth and Development, University of Texas Southwestern Medical Center at Dallas 75235 8591, USA
Nat Genet 14:25-32. 1996..Both EXT1 and EXT2 show significant homology with one additional expressed sequence tag, defining a new multigene family of proteins with potential tumour suppressor activity...
