Matthew C Stewart

Summary

Affiliation: University of Illinois
Country: USA

Publications

  1. ncbi Effect of fibroblast growth factor-2 on equine mesenchymal stem cell monolayer expansion and chondrogenesis
    Allison A Stewart
    Department of Clinical Science, College of Veterinary Medicine, University of Illinois, Urbana, IL 61802, USA
    Am J Vet Res 68:941-5. 2007
  2. ncbi Expression and activity of the CDK inhibitor p57Kip2 in chondrocytes undergoing hypertrophic differentiation
    Matthew C Stewart
    Department of Veterinary Clinical Medicine, University of Illinois at Urbana Champaign, Urbana, Illinois 61802, USA
    J Bone Miner Res 19:123-32. 2004
  3. ncbi Effect of hydroxyapatite/tricalcium-phosphate coating on osseointegration of plasma-sprayed titanium alloy implants
    Matthew Stewart
    Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois at Urbana Champaign, 1008W Hazelwood Drive, Urbana, Illinois 61802, USA
    J Biomed Mater Res A 69:1-10. 2004
  4. ncbi Responses of equine tendon- and bone marrow-derived cells to monolayer expansion with fibroblast growth factor-2 and sequential culture with pulverized tendon and insulin-like growth factor-I
    Sushmitha S Durgam
    Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois, Urbana, IL 61802, USA
    Am J Vet Res 73:162-70. 2012
  5. ncbi Comparison of equine tendon- and bone marrow-derived cells cultured on tendon matrix with or without insulin-like growth factor-I supplementation
    Sushmitha S Durgam
    Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois, Urbana, IL 61802, USA
    Am J Vet Res 73:153-61. 2012
  6. ncbi Effect of dexamethasone supplementation on chondrogenesis of equine mesenchymal stem cells
    Allison A Stewart
    Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois, Urbana, IL 61802, USA
    Am J Vet Res 69:1013-21. 2008
  7. ncbi Effects of sodium hyaluronate and triamcinolone acetonide on glucosaminoglycan metabolism in equine articular chondrocytes treated with interleukin-1
    Elysia C Schaefer
    Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois, Urbana, IL 61802, USA
    Am J Vet Res 70:1494-501. 2009
  8. ncbi Mesenchymal stem cells: characteristics, sources, and mechanisms of action
    Matthew C Stewart
    Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois, 1008 West Hazelwood Drive, Urbana, IL 61802, USA
    Vet Clin North Am Equine Pract 27:243-61. 2011
  9. ncbi Comparison of equine tendon-, muscle-, and bone marrow-derived cells cultured on tendon matrix
    Allison A Stewart
    Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois, Urbana, IL 61802, USA
    Am J Vet Res 70:750-7. 2009
  10. ncbi Effects of clinically relevant concentrations of glucosamine on equine chondrocytes and synoviocytes in vitro
    Christopher R Byron
    Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois, Urbana Champaign, IL 61801, USA
    Am J Vet Res 69:1129-34. 2008

Research Grants

  1. CELL CYCLE REGULATION IN ARTICULAR CHONDROCYTES
    Matthew Stewart; Fiscal Year: 2002

Collaborators

Detail Information

Publications16

  1. ncbi Effect of fibroblast growth factor-2 on equine mesenchymal stem cell monolayer expansion and chondrogenesis
    Allison A Stewart
    Department of Clinical Science, College of Veterinary Medicine, University of Illinois, Urbana, IL 61802, USA
    Am J Vet Res 68:941-5. 2007
    ..To determine whether fibroblast growth factor-2 (FGF-2) treatment of equine mesenchymal stem cells (MSCs) during monolayer expansion enhances subsequent chondrogenesis in a 3-dimensional culture system...
  2. ncbi Expression and activity of the CDK inhibitor p57Kip2 in chondrocytes undergoing hypertrophic differentiation
    Matthew C Stewart
    Department of Veterinary Clinical Medicine, University of Illinois at Urbana Champaign, Urbana, Illinois 61802, USA
    J Bone Miner Res 19:123-32. 2004
    ..The phenotypic consequences of p57 expression were assessed in an in vitro model of hypertrophic differentiation. Adenoviral p57 expression was not sufficient for CollX expression but did augment induction of CollX by BMP-2...
  3. ncbi Effect of hydroxyapatite/tricalcium-phosphate coating on osseointegration of plasma-sprayed titanium alloy implants
    Matthew Stewart
    Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois at Urbana Champaign, 1008W Hazelwood Drive, Urbana, Illinois 61802, USA
    J Biomed Mater Res A 69:1-10. 2004
    ....
  4. ncbi Responses of equine tendon- and bone marrow-derived cells to monolayer expansion with fibroblast growth factor-2 and sequential culture with pulverized tendon and insulin-like growth factor-I
    Sushmitha S Durgam
    Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois, Urbana, IL 61802, USA
    Am J Vet Res 73:162-70. 2012
    ..To compare in vitro expansion of equine tendon- and bone marrow-derived cells with fibroblast growth factor-2 (FGF-2) supplementation and sequential matrix synthesis with pulverized tendon and insulin-like growth factor-I (IGF-I)...
  5. ncbi Comparison of equine tendon- and bone marrow-derived cells cultured on tendon matrix with or without insulin-like growth factor-I supplementation
    Sushmitha S Durgam
    Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois, Urbana, IL 61802, USA
    Am J Vet Res 73:153-61. 2012
    ..To compare in vitro expansion, explant colonization, and matrix synthesis of equine tendon- and bone marrow-derived cells in response to insulin-like growth factor-I (IGF-I) supplementation...
  6. ncbi Effect of dexamethasone supplementation on chondrogenesis of equine mesenchymal stem cells
    Allison A Stewart
    Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois, Urbana, IL 61802, USA
    Am J Vet Res 69:1013-21. 2008
    ....
  7. ncbi Effects of sodium hyaluronate and triamcinolone acetonide on glucosaminoglycan metabolism in equine articular chondrocytes treated with interleukin-1
    Elysia C Schaefer
    Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois, Urbana, IL 61802, USA
    Am J Vet Res 70:1494-501. 2009
    ..CONCLUSIONS AND CLINICAL RELEVANCE-Results indicated that high concentrations of hyaluronic acid or triamcinolone acetonide alone or in combination mitigated effects of IL-1 administration on GAG catabolism of equine chondrocytes...
  8. ncbi Mesenchymal stem cells: characteristics, sources, and mechanisms of action
    Matthew C Stewart
    Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois, 1008 West Hazelwood Drive, Urbana, IL 61802, USA
    Vet Clin North Am Equine Pract 27:243-61. 2011
    ..Finally, the current understanding of the mechanisms by which MSCs influence repair and regeneration are discussed, with an emphasis on the clinical importance of MSC trophic activities...
  9. ncbi Comparison of equine tendon-, muscle-, and bone marrow-derived cells cultured on tendon matrix
    Allison A Stewart
    Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois, Urbana, IL 61802, USA
    Am J Vet Res 70:750-7. 2009
    ..To compare viability and biosynthetic capacities of cells isolated from equine tendon, muscle, and bone marrow grown on autogenous tendon matrix...
  10. ncbi Effects of clinically relevant concentrations of glucosamine on equine chondrocytes and synoviocytes in vitro
    Christopher R Byron
    Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois, Urbana Champaign, IL 61801, USA
    Am J Vet Res 69:1129-34. 2008
    ..To evaluate the effects of glucosamine on equine articular chondrocytes and synoviocytes at concentrations clinically relevant to serum and synovial fluid concentrations...
  11. ncbi Evaluation of experimentally induced injury to the superficial digital flexor tendon in horses by use of low-field magnetic resonance imaging and ultrasonography
    William M Karlin
    Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois, Urbana, IL 61802, USA
    Am J Vet Res 72:791-8. 2011
    ..To evaluate tendon injuries in horses over a 16-week period by use of ultrasonography and low-field magnetic resonance imaging (MRI)...
  12. ncbi Microtopographically patterned surfaces promote the alignment of tenocytes and extracellular collagen
    Ashish Kapoor
    Department of Chemical and Biomolecular Engineering, University of Illinois at Urbana Champaign, Urbana, IL 61801, USA
    Acta Biomater 6:2580-9. 2010
    ..These outcomes provide insights into the biology of tendon regeneration, thus providing guidance in the design of clinical procedures for tendon repair...
  13. ncbi Cell-based therapies: current issues and future directions
    Matthew C Stewart
    Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois, 1008 West Hazelwood Drive, Urbana, IL 61802, USA
    Vet Clin North Am Equine Pract 27:393-9. 2011
    ....
  14. ncbi Effects of radial shock waves on membrane permeability and viability of chondrocytes and structure of articular cartilage in equine cartilage explants
    Christopher R Byron
    Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois, Urbana, IL 61802 USA
    Am J Vet Res 66:1757-63. 2005
    ..Caution should be exercised when extremely high periarticular pulse doses are used until additional studies can determine the long-term outcome of these effects and appropriate periarticular treatment regimens can be validated...
  15. ncbi High-efficiency nonviral transfection of primary chondrocytes
    Jean F Welter
    Department of Orthopedics, Case Western Reserve University and University Hospitals of Cleveland, Cleveland, OH, USA
    Methods Mol Med 100:129-46. 2004
    ..In addition to the primary protocol, we present two additional reliable, albeit less efficient backup protocols, the first using exponential decay electroporation and the second FuGENE 6 transfection...
  16. ncbi The balance between endotoxin accumulation and clearance during particle-induced osteolysis in murine calvaria
    Joscelyn M Tatro
    Department of Orthopadics, Case Western Reserve University and University Hospitals of Cleveland, 11100 Euclid Avenue, Cleveland, Ohio 44106 5000, USA
    J Orthop Res 25:361-9. 2007
    ..This balance may regulate the rate of osteolysis in the murine calvaria model as well as in patients with aseptic loosening...

Research Grants1

  1. CELL CYCLE REGULATION IN ARTICULAR CHONDROCYTES
    Matthew Stewart; Fiscal Year: 2002
    ..The long-term goal of this project is to identify critical regulatory factors that can be targeted to therapeutically modulate the intrinsic proliferative activity of articular chondrocyte in vivo. ..