Richard G Stevens

Summary

Affiliation: University of Connecticut Health Center
Country: USA

Publications

  1. ncbi request reprint Electric light causes cancer? Surely you're joking, Mr. Stevens
    Richard G Stevens
    Department of Community Medicine and Health Care, University of Connecticut Health Center, School of Medicine, 263 Farmington Avenue, Farmington, CT 06030 6325, USA
    Mutat Res 682:1-6. 2009
  2. ncbi request reprint Working against our endogenous circadian clock: Breast cancer and electric lighting in the modern world
    Richard G Stevens
    University of Connecticut Health Center, Farmington, CT 06032, United States
    Mutat Res 680:106-8. 2009
  3. doi request reprint Response to Ijaz S, et al. "Night-shift work and breast cancer - a systematic review and meta-analysis"
    Richard G Stevens
    University of Connecticut Health Center, Farmington, CT, USA
    Scand J Work Environ Health 39:631-2. 2013
  4. doi request reprint Adverse health effects of nighttime lighting: comments on American Medical Association policy statement
    Richard G Stevens
    University of Connecticut Health Center, Farmington, Connecticut 06030 6325, USA
    Am J Prev Med 45:343-6. 2013
  5. doi request reprint Invited commentary: validity of case-control studies of sleep duration and breast cancer
    Richard G Stevens
    University of Connecticut Health Center, 263 Farmington Avenue, Farmington, CT 06030 6325, USA
    Am J Epidemiol 177:328-30. 2013
  6. doi request reprint Body iron stores and breast cancer risk in female atomic bomb survivors
    Richard G Stevens
    Department of Community Medicine, UCONN Health Center, Farmington, Connecticut, USA
    Cancer Sci 102:2236-40. 2011
  7. doi request reprint Does electric light stimulate cancer development in children?
    Richard G Stevens
    Department of Community Medicine, University of Connecticut Health Center, Farmington, Connecticut 06030, USA
    Cancer Epidemiol Biomarkers Prev 21:701-4. 2012
  8. pmc Light-at-night, circadian disruption and breast cancer: assessment of existing evidence
    Richard G Stevens
    Department of Community Medicine, University of Connecticut Health Center, 263 Farmington Avenue, Farmington, CT 06030 6325, USA
    Int J Epidemiol 38:963-70. 2009
  9. doi request reprint Considerations of circadian impact for defining 'shift work' in cancer studies: IARC Working Group Report
    Richard G Stevens
    University of Connecticut Health Center, Farmington, CT 06030, USA
    Occup Environ Med 68:154-62. 2011
  10. pmc Meeting report: the role of environmental lighting and circadian disruption in cancer and other diseases
    Richard G Stevens
    Department of Community Medicine, University of Connecticut Health Center, Farmington, Connecticut 06030 6325, USA
    Environ Health Perspect 115:1357-62. 2007

Detail Information

Publications28

  1. ncbi request reprint Electric light causes cancer? Surely you're joking, Mr. Stevens
    Richard G Stevens
    Department of Community Medicine and Health Care, University of Connecticut Health Center, School of Medicine, 263 Farmington Avenue, Farmington, CT 06030 6325, USA
    Mutat Res 682:1-6. 2009
    ..Although it may seem logical now, the journey on the path from electric light to breast cancer has been a tortuous one, at least for me...
  2. ncbi request reprint Working against our endogenous circadian clock: Breast cancer and electric lighting in the modern world
    Richard G Stevens
    University of Connecticut Health Center, Farmington, CT 06032, United States
    Mutat Res 680:106-8. 2009
    ..g., shift work) can induce deleterious epigenetic changes in these genes...
  3. doi request reprint Response to Ijaz S, et al. "Night-shift work and breast cancer - a systematic review and meta-analysis"
    Richard G Stevens
    University of Connecticut Health Center, Farmington, CT, USA
    Scand J Work Environ Health 39:631-2. 2013
    ....
  4. doi request reprint Adverse health effects of nighttime lighting: comments on American Medical Association policy statement
    Richard G Stevens
    University of Connecticut Health Center, Farmington, Connecticut 06030 6325, USA
    Am J Prev Med 45:343-6. 2013
    ..There are practical implications of the basic and epidemiologic science in the form of advancing lighting technologies that better accommodate human circadian rhythmicity. ..
  5. doi request reprint Invited commentary: validity of case-control studies of sleep duration and breast cancer
    Richard G Stevens
    University of Connecticut Health Center, 263 Farmington Avenue, Farmington, CT 06030 6325, USA
    Am J Epidemiol 177:328-30. 2013
    ..Girschik et al. (Am J Epidemiol. 2013;177(4):316-327) have tested the latter in a case-control study. Although the case-control design is useful for many questions, it is probably not useful for studies of sleep duration and health...
  6. doi request reprint Body iron stores and breast cancer risk in female atomic bomb survivors
    Richard G Stevens
    Department of Community Medicine, UCONN Health Center, Farmington, Connecticut, USA
    Cancer Sci 102:2236-40. 2011
    ..The results support the hypothesis that elevated body iron stores increase the risk of breast cancer. However, the study was inconclusive regarding the question of whether body iron alters radiation-induced breast cancer risk...
  7. doi request reprint Does electric light stimulate cancer development in children?
    Richard G Stevens
    Department of Community Medicine, University of Connecticut Health Center, Farmington, Connecticut 06030, USA
    Cancer Epidemiol Biomarkers Prev 21:701-4. 2012
    ..There are practical implications and interventions that accrue from this idea should it later be confirmed to be true...
  8. pmc Light-at-night, circadian disruption and breast cancer: assessment of existing evidence
    Richard G Stevens
    Department of Community Medicine, University of Connecticut Health Center, 263 Farmington Avenue, Farmington, CT 06030 6325, USA
    Int J Epidemiol 38:963-70. 2009
    ..The possibility that a portion of the breast cancer burden might be explained by the introduction and increasing use of electricity to light the night was suggested >20 years ago...
  9. doi request reprint Considerations of circadian impact for defining 'shift work' in cancer studies: IARC Working Group Report
    Richard G Stevens
    University of Connecticut Health Center, Farmington, CT 06030, USA
    Occup Environ Med 68:154-62. 2011
    ..The group also recognised that for further domains to be identified, more research needs to be conducted on the impact of various shift schedules and routines on physiological and circadian rhythms of workers in real-world environments...
  10. pmc Meeting report: the role of environmental lighting and circadian disruption in cancer and other diseases
    Richard G Stevens
    Department of Community Medicine, University of Connecticut Health Center, Farmington, Connecticut 06030 6325, USA
    Environ Health Perspect 115:1357-62. 2007
    ..Third are effects of light-induced physiologic disruption on disease occurrence and prognosis, and how prevention and treatment could be improved by application of this knowledge...
  11. pmc Breast cancer and circadian disruption from electric lighting in the modern world
    Richard G Stevens
    Professor, Department of Community Medicine, University of Connecticut Health Center, Farmington, CT
    CA Cancer J Clin 64:207-18. 2014
    ....
  12. ncbi request reprint HFE mutation and dietary iron content interact to increase ischemia/reperfusion injury of the heart in mice
    Tibor Turoczi
    Department of Surgery, University of Connecticut School of Medicine, Farmington, Conn 06030 1110, USA
    Circ Res 92:1240-6. 2003
    ..The results suggest that increased amount of ROS and reduced antioxidant reserve secondary to iron overloading may be instrumental for the susceptibility of the HFE gene knockout mice to cardiac injury...
  13. ncbi request reprint Dietary iron promotes azoxymethane-induced colon tumors in mice
    Jillian N M Ilsley
    Center for Molecular Medicine, University of Connecticut Health Center, Farmington, CT 06030, USA
    Nutr Cancer 49:162-9. 2004
    ..Our results suggest that, following carcinogen exposure, elevated dietary iron promotes the growth of tumors with altered cellular homeostasis through a mechanism that is independent of oxidative stress...
  14. ncbi request reprint Circadian disruption and breast cancer: from melatonin to clock genes
    Richard G Stevens
    Department of Community Medicine, University of Connecticut Health Center, Farmington, Connecticut 06030 6325, USA
    Epidemiology 16:254-8. 2005
    ..Epidemiologic studies should consider gene and environment interactions such as circadian gene variants and shift work requirements on the job...
  15. pmc Phenotypic effects of the circadian gene Cryptochrome 2 on cancer-related pathways
    Aaron E Hoffman
    Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT, USA
    BMC Cancer 10:110. 2010
    ..As such, aberrant expression of CRY2 may influence carcinogenic processes and thereby impact cancer susceptibility...
  16. ncbi request reprint Mutations in BRAF and KRAS differentially distinguish serrated versus non-serrated hyperplastic aberrant crypt foci in humans
    Daniel W Rosenberg
    Colon Cancer Prevention Program, Neag Comprehensive Cancer Center, and Center for Molecular Medicine, University of Connecticut Health Center, 263 Farmington Avenue, Farmington, CT 06030, USA
    Cancer Res 67:3551-4. 2007
    ....
  17. ncbi request reprint Shift work, light at night, and breast cancer on Long Island, New York
    Erin S O'Leary
    Department of Preventive Medicine, School of Medicine, Stony Brook University, Stony Brook, NY 11794 8036, USA
    Am J Epidemiol 164:358-66. 2006
    ..Furthermore, overall and evening shift work were not significant factors, and analyses of overnight shift workers yielded reduced risk estimates. The study thus provides mixed evidence for the light-at-night hypothesis...
  18. ncbi request reprint Artificial lighting in the industrialized world: circadian disruption and breast cancer
    Richard G Stevens
    University of Connecticut Health Center, Farmington, CT 06030 6325, USA
    Cancer Causes Control 17:501-7. 2006
    ..Exogenous melatonin may therefore contribute to circadian disruption rather than alleviate it...
  19. pmc Epidemiology of colonic aberrant crypt foci: review and analysis of existing studies
    Richard G Stevens
    Colon Cancer Prevention Program CCPP, Neag Comprehensive Cancer Center, University of Connecticut Health Center UCHC, 263 Farmington Avenue, Farmington, CT 06030 6325, United States
    Cancer Lett 252:171-83. 2007
    ..This information can then be used to improve the design of prospective studies, and of clinical intervention trials that use ACF as an intermediate endpoint...
  20. ncbi request reprint Alcohol consumption and serum hormone levels during pregnancy
    Richard G Stevens
    Department of Community Medicine, University of Connecticut Health Center, 263 Farmington Ave, Farmington, CT 06030, USA
    Alcohol 36:47-53. 2005
    ..Light alcohol intake during pregnancy is associated with lower maternal testosterone. The health implications are uncertain, but may include an increased breast density in the daughters of drinking mothers...
  21. ncbi request reprint Baseline serum C-reactive protein and death from colorectal cancer in the NHANES III cohort
    Helen Swede
    Department of Community Medicine and Health Care, University of Connecticut Health Center, Farmington, CT
    Int J Cancer 134:1862-70. 2014
    ..Future research is recommended to confirm emerging data that elevated serologic CRP might reflect underlying colonic inflammation. ..
  22. pmc Number of aberrant crypt foci associated with adiposity and IGF1 bioavailability
    Helen Swede
    Colon Cancer Prevention Program, Neag Comprehensive Cancer Center, University of Connecticut Health Center, 263 Farmington Avenue, Farmington, CT 06030 6325, USA
    Cancer Causes Control 20:653-61. 2009
    ..Evidence has been derived from studies of cancer and polyps. Supporting data about aberrant crypt foci (ACF), putative pre-polyp changes, have been generated only from animal studies to date...
  23. doi request reprint Prevalence and prognostic role of triple-negative breast cancer by race: a surveillance study
    Helen Swede
    Department of Community Medicine and Health Care, University of Connecticut School of Medicine, Farmington, CT 06030, USA
    Clin Breast Cancer 11:332-41. 2011
    ..No reports however have been generated from a statewide cancer registry...
  24. ncbi request reprint Lighting during the day and night: possible impact on risk of breast cancer
    Richard G Stevens
    UCONN Health Center, University of Connecticut, Farmington, CT, USA
    Neuro Endocrinol Lett 23:57-60. 2002
    ..Many candidate factors exist, each with a cadre of proponents. The sum of these may turn out to explain the bulk of the excess risk in modern societies. On the other hand, they may not, and worse, may fall woefully short...
  25. pmc Shiftwork and prostate-specific antigen in the National Health and Nutrition Examination Survey
    Erin E Flynn-Evans
    Division of Sleep Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02115, USA
    J Natl Cancer Inst 105:1292-7. 2013
    ..Our aim was to investigate the relationship between shiftwork and prostate-specific antigen (PSA) test obtained as part of the National Health and Nutrition Examination Survey (NHANES) study...
  26. pmc Epigenetic impact of long-term shiftwork: pilot evidence from circadian genes and whole-genome methylation analysis
    Yong Zhu
    Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT 06520, USA
    Chronobiol Int 28:852-61. 2011
    ..Considering there are millions of shiftworkers worldwide, understanding the effects of this exposure may lead to novel strategies for cancer prevention and new policies regulating shiftwork...
  27. ncbi request reprint Aberrant crypt foci in patients with a positive family history of sporadic colorectal cancer
    Richard G Stevens
    Colon Cancer Prevention Program, Neag Comprehensive Cancer Center, University of Connecticut Health Center, CT, USA
    Cancer Lett 248:262-8. 2007
    ..4; the mean was significantly higher in the patients with a positive family history of CRC (9.0, p<0.01; n=43) or a personal history of advanced adenoma (7.5, p<0.05; n=34)...
  28. ncbi request reprint Oxidative damage in colon and mammary tissue of the HFE-knockout mouse
    Richard G Stevens
    Department of Community Medicine, University of Connecticut Health Center, Farmington 06030, USA
    Free Radic Biol Med 34:1212-6. 2003
    ..226, p =.02) tissue among those mice on the standard iron diet compared to those on the low iron diet. These results suggest that dietary modification may affect the course of iron overload from HFE mutations...