Research Topics
Genomes and Genes
Species | Mariana C SternSummaryAffiliation: University of Southern California Country: USA Publications
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Detail Information
Publications
Sequence variant on 3q28 and urinary bladder cancer risk: findings from the Los Angeles-Shanghai bladder case-control studyMariana C Stern
Department of Preventive Medicine, Keck School of Medicine, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California 90089, USA
Cancer Epidemiol Biomarkers Prev 18:3057-61. 2009..045). Our results suggest that a TP63 gene variant may increase susceptibility for the development of urinary bladder tumors with low risk of progression...- Polymorphisms in DNA repair genes, smoking, and bladder cancer risk: findings from the international consortium of bladder cancerMariana C Stern
Department of Preventive Medicine, Keck School of Medicine, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA 90089, USA
Cancer Res 69:6857-64. 2009..002) and was strongest for the highest levels of smoking dose and smoking duration. Overall, our study provides the strongest evidence to date for a role of common variants in DNA repair genes in bladder carcinogenesis... 
DNA repair single-nucleotide polymorphisms in colorectal cancer and their role as modifiers of the effect of cigarette smoking and alcohol in the Singapore Chinese Health StudyMariana C Stern
Department of Preventive Medicine, Keck School of Medicine, Norris Comprehensive Cancer Center, University of Southern California, 1441 Eastlake Avenue, Room 5421A, Los Angeles, CA 90089, USA
Cancer Epidemiol Biomarkers Prev 16:2363-72. 2007..8; 95% CI, 1.0-8.1). Our results support a role for reactive oxygen species as relevant genotoxins that may account for the effects of both smoking and alcohol on colorectal cancer risk...- XRCC1, XRCC3, and XPD polymorphisms as modifiers of the effect of smoking and alcohol on colorectal adenoma riskMariana C Stern
University of Southern California Norris Comprehensive Cancer Center, Keck School of Medicine, 1441 Eastlake Avenue, Room 5421A, Los Angeles, CA 90089, USA
Cancer Epidemiol Biomarkers Prev 15:2384-90. 2006..04). Our data suggest that the effects of smoking and alcohol may vary depending on the genetic background of proteins that participate in the base excision repair and nucleotide excision repair pathways... - Polyunsaturated fatty acids, DNA repair single nucleotide polymorphisms and colorectal cancer in the Singapore Chinese Health StudyMariana C Stern
Department of Preventive Medicine, Keck School of Medicine, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA 90089, USA
J Nutrigenet Nutrigenomics 2:273-9. 2009..003). Our results suggest a positive association between high intake of marine n-3 PUFA and rectal cancer risk among carriers of at least one PARP codon 762 Ala allele (odds ratio=1.7, 95% confidence interval=1.1-2.7)... - Polymorphisms in base excision repair genes as colorectal cancer risk factors and modifiers of the effect of diets high in red meatAsgeir Brevik
Department of Preventive Medicine, Keck School of Medicine, Norris Comprehensive Cancer Center, University of Southern California, California 90089, USA
Cancer Epidemiol Biomarkers Prev 19:3167-73. 2010..Carcinogens generated during meat cooking have been implicated as causal agents and can induce oxidative DNA damage, which elicits repair by the base excision repair (BER) pathway... - Red meat and poultry, cooking practices, genetic susceptibility and risk of prostate cancer: results from a multiethnic case-control studyAmit D Joshi
Department of Preventive Medicine, University of Southern California Keck School of Medicine, Norris Comprehensive Cancer Center Los Angeles, CA 90033, USA
Carcinogenesis 33:2108-18. 2012..008). Our results support a role for carcinogens that accumulate in meats cooked at high temperatures as potential PCA risk factors, and may support a role for heterocyclic amines (HCAs) in PCA etiology... 
Carcinogen metabolism genes, red meat and poultry intake, and colorectal cancer riskJun Wang
Department of Preventive Medicine, Keck School of Medicine, Norris Comprehensive Cancer Center, University of Southern California, CA, USA
Int J Cancer 130:1898-907. 2012..Our findings also suggest a possible role for diets high in poultry cooked at high temperatures in CRC risk...- Hypertension, diuretics and antihypertensives in relation to bladder cancerXuejuan Jiang
Department of Preventive Medicine, Keck School of Medicine, Norris Comprehensive Cancer Center, University of Southern California, 1441 Eastlake Avenue, Los Angeles, CA 90089, USA
Carcinogenesis 31:1964-71. 2010..7 pg/g Hb) compared with individuals without hypertension (79.8 pg/g Hb) (P = 0.009). In conclusion, untreated hypertension was associated with a reduced risk of bladder cancer... - Polymorphisms in carcinogen metabolism enzymes, fish intake, and risk of prostate cancerChelsea Catsburg
Department of Preventive Medicine, University of Southern California Keck School of Medicine, Norris Comprehensive Cancer Center, Los Angeles, CA 90033, USA
Carcinogenesis 33:1352-9. 2012..However, the gene-diet interactions should be interpreted with caution given the limited sample size. Thus, our findings require further validation with additional studies... - Risk of urinary bladder cancer is associated with 8q24 variant rs9642880[T] in multiple racial/ethnic groups: results from the Los Angeles-Shanghai case-control studyVictoria K Cortessis
Department of Preventive Medicine, Keck School of Medicine, Norris Comprehensive Cancer Center, University of Southern California, 1441 Eastlake Ave, MC 9175, Los Angeles, CA 90089, USA
Cancer Epidemiol Biomarkers Prev 19:3150-6. 2010..Recent genome-wide association studies of urinary bladder cancer report risk to be associated with the T allele of rs9642880 on 8q24 among individuals of European descent... - Genetic variations on chromosomes 5p15 and 15q25 and bladder cancer risk: findings from the Los Angeles-Shanghai bladder case-control studyManuela Gago-Dominguez
Department of Preventive Medicine, Keck School of Medicine, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA 90089 9175, USA
Carcinogenesis 32:197-202. 2011..26; 95% CI, 1.04-1.54; P = 0.017). Our results support 5p15 and 15q25 as susceptibility regions for bladder cancer risk... - Cigarette smoking and subtypes of bladder cancerXuejuan Jiang
Department of Preventive Medicine, Keck School of Medicine, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA, USA
Int J Cancer 130:896-901. 2012..Our results indicate that cigarette smoking was more strongly associated with increased risk of invasive bladder cancer than with low-grade superficial bladder cancer... - Genetic variation in insulin pathway genes and distal colorectal adenoma riskA Joan Levine
Department of Preventive Medicine, Genetic Epidemiology, University of Southern California Keck School of Medicine, NRT 1450 Biggy Street Room 1509A, Los Angeles, CA 90033, USA
Int J Colorectal Dis 27:1587-95. 2012.... - DNA repair gene polymorphisms and probability of p53 mutation in bladder cancerMariana C Stern
Department of Preventive Medicine, University of Southern California, Keck School of Medicine, Norris Comprehensive Cancer Center, Los Angeles, USA
Mol Carcinog 45:715-9. 2006..7; 95% CI = 1.1-13). Our data provide some limited support for the hypothesis that mutations in the p53 gene in bladder cancer may differ according to the presence or absence of certain DNA repair gene variants... - XRCC1 and XRCC3 polymorphisms and their role as effect modifiers of unsaturated fatty acids and antioxidant intake on colorectal adenomas riskMariana C Stern
Department of Preventive Medicine, Keck School of Medicine, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA 90089, USA
Cancer Epidemiol Biomarkers Prev 14:609-15. 2005.... - Red meat and poultry intake, polymorphisms in the nucleotide excision repair and mismatch repair pathways and colorectal cancer riskAmit D Joshi
Department of Preventive Medicine, Keck School of Medicine, Norris Comprehensive Cancer Center, University of Southern California, CA 90089, USA
Carcinogenesis 30:472-9. 2009..These findings highlight the possible contribution of diets high in red meat to the formation of lesions that elicit the NER pathway, such as carcinogen-induced bulky adducts... - Fish intake, cooking practices, and risk of prostate cancer: results from a multi-ethnic case-control studyAmit D Joshi
Department of Preventive Medicine, University of Southern California Keck School of Medicine, Norris Comprehensive Cancer Center, Los Angeles, CA 90089, USA
Cancer Causes Control 23:405-20. 2012..In this study, we investigated the association between fish intake and localized and advanced PCA taking into account fish types (lean vs. fatty) and cooking practices... - Variation in folate pathway genes and distal colorectal adenoma risk: a sigmoidoscopy-based case-control studyA Joan Levine
Department of Preventive Medicine, Genetic Epidemiology, University of Southern California Keck School of Medicine, Los Angeles, CA 90033, USA
Cancer Causes Control 22:541-52. 2011..Folate-associated one-carbon metabolism (FOCM) is an important pathway in colorectal neoplasia risk but data on genetic variation in this pathway are largely limited to studies of single SNPs in selected genes... - Lower risk in parous women suggests that hormonal factors are important in bladder cancer etiologyCarol A Davis-Dao
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
Cancer Epidemiol Biomarkers Prev 20:1156-70. 2011..Our objective was to determine whether hormonal and reproductive factors are involved in female bladder cancer... - Genetic admixture and risk of hypertensive disorders of pregnancy among Latinas in Los Angeles CountyAhva Shahabi
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089, USA
Epidemiology 24:285-94. 2013..This study examines the role of genetic ancestry and environmental risk factors in the risk of hypertensive disorder of pregnancy among Latinas in Los Angeles County... - A review of cancer in U.S. Hispanic populationsRobert W Haile
Department of Preventive Medicine, University of Southern California, Los Angeles, CA 90033, USA
Cancer Prev Res (Phila) 5:150-63. 2012..We review the literature and discuss study design options and features that should be considered in future studies... - Differences in base excision repair capacity may modulate the effect of dietary antioxidant intake on prostate cancer risk: an example of polymorphisms in the XRCC1 geneCarla H van Gils
Molecular and Genetic Epidemiology Section, Laboratory of Molecular Carcinogenesis National Institute of Environmental Health Sciences, NIH, Research Triangle Park, North Carolina 27709, USA
Cancer Epidemiol Biomarkers Prev 11:1279-84. 2002..The data give some support for our hypothesis but should be regarded as preliminary, because it is limited by small sample size. We discuss what kind of data and what kind of studies are needed for future evaluation of this hypothesis... - XPD codon 751 polymorphism, metabolism genes, smoking, and bladder cancer riskMariana C Stern
Molecular and Genetic Epidemiology Section, Laboratory of Molecular Carcinogenesis and the National Institute of Environmental Health Sciences, NIH, Research Triangle Park, North Carolina, 27709, USA
Cancer Epidemiol Biomarkers Prev 11:1004-11. 2002..52). We found little evidence for a gene-gene-exposure, three-way interaction among the XPD codon 751 genotype, smoking, and the NAT1/NAT2 genotype... - DNA repair gene XRCC3 codon 241 polymorphism, its interaction with smoking and XRCC1 polymorphisms, and bladder cancer riskMariana C Stern
Molecular and Genetic Epidemiology Section, Laboratory of Molecular Carcinogenesis, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, North Carolina 27709, USA
Cancer Epidemiol Biomarkers Prev 11:939-43. 2002..In this study, we found some evidence for a gene-gene interaction between the XRCC1 codon 194 and XRCC3 codon 241 polymorphisms (P = 0.09) and some support for a possible gene-gene-smoking three-way interaction (P = 0.08)...