D H Sterman

Summary

Affiliation: University of Pennsylvania
Country: USA

Publications

  1. ncbi request reprint Advances in the treatment of malignant pleural mesothelioma
    D H Sterman
    Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pennsylvania Medical Center, Philadelphia 19104, USA
    Chest 116:504-20. 1999
  2. ncbi request reprint A phase I clinical trial of single-dose intrapleural IFN-beta gene transfer for malignant pleural mesothelioma and metastatic pleural effusions: high rate of antitumor immune responses
    Daniel H Sterman
    Thoracic Oncology Gene Therapy Program and Abramson Family Cancer Research Institute, University of Pennsylvania Medical Center, Philadelphia, PA 19104 4283, USA
    Clin Cancer Res 13:4456-66. 2007
  3. ncbi request reprint Gene therapy for malignant pleural mesothelioma
    Daniel H Sterman
    Thoracic Oncology Research Laboratory, Pulmonary, Allergy, and Critical Care Division, Department of Medicine, University of Pennsylvania Medical Center, Philadelphia, PA 19104 4283, USA
    Hematol Oncol Clin North Am 19:1147-73, viii. 2005
  4. ncbi request reprint Long-term follow-up of patients with malignant pleural mesothelioma receiving high-dose adenovirus herpes simplex thymidine kinase/ganciclovir suicide gene therapy
    Daniel H Sterman
    Thoracic Oncology Research Laboratory, University of Pennsylvania Medical Center, Philadelphia, PA 19104 4283, USA
    Clin Cancer Res 11:7444-53. 2005
  5. ncbi request reprint Advances in the diagnosis, evaluation, and management of malignant pleural mesothelioma
    Daniel H Sterman
    Thoracic Oncology Research Laboratory, Interventional Pulmonology Program, Pulmonary, Allergy and Critical Care Division, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania 19104 4283, USA
    Respirology 10:266-83. 2005
  6. ncbi request reprint Diagnosis and staging of "other bronchial tumors"
    Daniel H Sterman
    Pulmonary, Allergy, and Critical Care Division, University of Pennsylvania Medical Center, Philadelphia, 833 West Gates Building, 3400 Spruce Street, Philadelphia, PA 19104, USA
    Chest Surg Clin N Am 13:79-94. 2003
  7. ncbi request reprint A pilot study of systemic corticosteroid administration in conjunction with intrapleural adenoviral vector administration in patients with malignant pleural mesothelioma
    D H Sterman
    Division of Pulmonary and Critical Care Medicine, University of Pennsylvania Medical Center, Philadelphia 19104, USA
    Cancer Gene Ther 7:1511-8. 2000
  8. ncbi request reprint Eradication of intraperitoneal and distant tumor by adenovirus-mediated interferon-beta gene therapy is attributable to induction of systemic immunity
    M Odaka
    Thoracic Oncology Research Laboratory, Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania 19104, USA
    Cancer Res 61:6201-12. 2001
  9. ncbi request reprint Immuno-gene therapy with interferon-beta before surgical debulking delays recurrence and improves survival in a murine model of malignant mesothelioma
    Robert J Kruklitis
    Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, USA
    J Thorac Cardiovasc Surg 127:123-30. 2004
  10. ncbi request reprint Intrapulmonary IFN-beta gene therapy using an adenoviral vector is highly effective in a murine orthotopic model of bronchogenic adenocarcinoma of the lung
    Michael J Wilderman
    Thoracic Oncology Research Laboratory, University of Pennsylvania Medical School, Philadelphia, Pennsylvania 19014 6160, USA
    Cancer Res 65:8379-87. 2005

Detail Information

Publications35

  1. ncbi request reprint Advances in the treatment of malignant pleural mesothelioma
    D H Sterman
    Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pennsylvania Medical Center, Philadelphia 19104, USA
    Chest 116:504-20. 1999
    ..These promising new avenues may modify the therapeutic nihilism that is rampant among clinicians dealing with mesothelioma...
  2. ncbi request reprint A phase I clinical trial of single-dose intrapleural IFN-beta gene transfer for malignant pleural mesothelioma and metastatic pleural effusions: high rate of antitumor immune responses
    Daniel H Sterman
    Thoracic Oncology Gene Therapy Program and Abramson Family Cancer Research Institute, University of Pennsylvania Medical Center, Philadelphia, PA 19104 4283, USA
    Clin Cancer Res 13:4456-66. 2007
    ..IFN-beta) in patients with malignant pleural mesothelioma (MPM) and metastatic pleural effusions (MPE)...
  3. ncbi request reprint Gene therapy for malignant pleural mesothelioma
    Daniel H Sterman
    Thoracic Oncology Research Laboratory, Pulmonary, Allergy, and Critical Care Division, Department of Medicine, University of Pennsylvania Medical Center, Philadelphia, PA 19104 4283, USA
    Hematol Oncol Clin North Am 19:1147-73, viii. 2005
    ..These trials serve multiple purposes: to establish safety, determine proper dosing, evaluate for efficacy, and, in an iterative fashion, guide future avenues of laboratory investigation...
  4. ncbi request reprint Long-term follow-up of patients with malignant pleural mesothelioma receiving high-dose adenovirus herpes simplex thymidine kinase/ganciclovir suicide gene therapy
    Daniel H Sterman
    Thoracic Oncology Research Laboratory, University of Pennsylvania Medical Center, Philadelphia, PA 19104 4283, USA
    Clin Cancer Res 11:7444-53. 2005
    ..HSVtk) in combination with systemic ganciclovir...
  5. ncbi request reprint Advances in the diagnosis, evaluation, and management of malignant pleural mesothelioma
    Daniel H Sterman
    Thoracic Oncology Research Laboratory, Interventional Pulmonology Program, Pulmonary, Allergy and Critical Care Division, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania 19104 4283, USA
    Respirology 10:266-83. 2005
    ..Over the past decade, significant advances have been made on several fronts that have improved the ability to diagnose a stage, define prognosis, and treat malignant pleural mesothelioma...
  6. ncbi request reprint Diagnosis and staging of "other bronchial tumors"
    Daniel H Sterman
    Pulmonary, Allergy, and Critical Care Division, University of Pennsylvania Medical Center, Philadelphia, 833 West Gates Building, 3400 Spruce Street, Philadelphia, PA 19104, USA
    Chest Surg Clin N Am 13:79-94. 2003
    ..Staging of these lesions is assessed after proper resection; however, mediastinoscopy should be performed if preoperative mediastinal adenopathy is appreciated...
  7. ncbi request reprint A pilot study of systemic corticosteroid administration in conjunction with intrapleural adenoviral vector administration in patients with malignant pleural mesothelioma
    D H Sterman
    Division of Pulmonary and Critical Care Medicine, University of Pennsylvania Medical Center, Philadelphia 19104, USA
    Cancer Gene Ther 7:1511-8. 2000
    ....
  8. ncbi request reprint Eradication of intraperitoneal and distant tumor by adenovirus-mediated interferon-beta gene therapy is attributable to induction of systemic immunity
    M Odaka
    Thoracic Oncology Research Laboratory, Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania 19104, USA
    Cancer Res 61:6201-12. 2001
    ....
  9. ncbi request reprint Immuno-gene therapy with interferon-beta before surgical debulking delays recurrence and improves survival in a murine model of malignant mesothelioma
    Robert J Kruklitis
    Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, USA
    J Thorac Cardiovasc Surg 127:123-30. 2004
    ....
  10. ncbi request reprint Intrapulmonary IFN-beta gene therapy using an adenoviral vector is highly effective in a murine orthotopic model of bronchogenic adenocarcinoma of the lung
    Michael J Wilderman
    Thoracic Oncology Research Laboratory, University of Pennsylvania Medical School, Philadelphia, Pennsylvania 19014 6160, USA
    Cancer Res 65:8379-87. 2005
    ..IFNbeta. These studies, showing remarkable antitumor activity in this orthotopic lung cancer model, provide strong preclinical support for a trial of Ad.IFNbeta to treat human non-small cell lung cancer...
  11. doi request reprint A multicenter pilot study of a bronchial valve for the treatment of severe emphysema
    D H Sterman
    University of Pennsylvania Medical Center, Philadelphia, PA 19104 4283, USA
    Respiration 79:222-33. 2010
    ..Surgical treatments for severe COPD with emphysema are effective for highly selected patients. A minimally invasive method for treating emphysema could decrease morbidity and increase acceptance by patients...
  12. doi request reprint Donor transmission of malignant melanoma in a lung transplant recipient 32 years after curative resection
    Navkaranbir S Bajaj
    University of Alabama, Ryals School of Public Health, Birmingham, AL, USA
    Transpl Int 23:e26-31. 2010
    ....
  13. ncbi request reprint High-dose-rate (HDR) brachytherapy for the treatment of benign obstructive endobronchial granulation tissue
    Chika N Madu
    Department of Radiation Oncology, University of Pennsylvania Medical Center, Philadelphia, PA 19104, USA
    Int J Radiat Oncol Biol Phys 66:1450-6. 2006
    ..This study describes a series of refractory patients treated with high-dose-rate (HDR) brachytherapy for benign proliferation of granulation tissue, causing airway compromise...
  14. ncbi request reprint Interferon beta adenoviral gene therapy in a patient with ovarian cancer
    Daniel H Sterman
    Thoracic Oncology Research Laboratory, University of Pennsylvania, Philadelphia, PA, USA
    Nat Clin Pract Oncol 3:633-9. 2006
    ..Diagnosis Stage IV ovarian cancer with malignant ascites and pleural effusion. Management Tunneled pleural catheter and intrapleural adenoviral-mediated interferon beta gene therapy...
  15. ncbi request reprint Cytokine gene therapy for malignant pleural mesothelioma
    Anil Vachani
    Thoracic Oncology Research Laboratory, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania, USA
    J Thorac Oncol 2:265-7. 2007
  16. pmc Evaluation of an attenuated vesicular stomatitis virus vector expressing interferon-beta for use in malignant pleural mesothelioma: heterogeneity in interferon responsiveness defines potential efficacy
    Vassiliki Saloura
    Thoracic Oncology Research Laboratory, University of Pennsylvania Medical Center, Philadelphia, PA 19104, USA
    Hum Gene Ther 21:51-64. 2010
    ..However, it may be feasible to prescreen individual susceptibility to VSV.IFN-beta by immunostaining for the presence of p48 protein...
  17. pmc A phase I trial of repeated intrapleural adenoviral-mediated interferon-beta gene transfer for mesothelioma and metastatic pleural effusions
    Daniel H Sterman
    Section of Interventional Pulmonology and Thoracic Oncology, Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania 19104 4283, USA
    Mol Ther 18:852-60. 2010
    ..This approach was safe, induced immune responses and disease stability. However, rapid development of Nabs prevented effective gene transfer after the second dose, even with a dose interval as short as 7 days...
  18. pmc Advances in diagnostic bronchoscopy
    Andrew R Haas
    Clinical Operations, Interventional Pulmonology and Thoracic Oncology, Pulmonary, Allergy, and Critical Care Division, University of Pennsylvania Medical Center, 3600 Spruce Street, Philadelphia, PA 19104 4283, USA
    Am J Respir Crit Care Med 182:589-97. 2010
    ..In this review, we provide a contemporary review of diagnostic bronchoscopy developments over the past decade...
  19. ncbi request reprint Gene therapy for lung neoplasms
    Steven M Albelda
    Division of Pulmonary, Allergy, and Critical Care, Department of Medicine, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania, USA
    Clin Chest Med 23:265-77. 2002
    ..Given the progress so far, there is little doubt that gene therapy will become a key approach for the treatment of thoracic malignancies in the near future...
  20. ncbi request reprint Outpatient management of malignant pleural effusions with small-bore, tunneled pleural catheters
    Ali I Musani
    Interventional Pulmonology Program, Division of Pulmonary, Allergy and Critical Care Medicine, University of Pennsylvania Medical Center, Philadelphia, PA 19104 4283, USA
    Respiration 71:559-66. 2004
    ..Control of MPEs to palliate respiratory symptoms can be performed via several different approaches. Ideally, a minimally invasive procedure to control MPEs and to provide relief of respiratory symptoms would be optimal...
  21. ncbi request reprint Regulatory T cells and cytokines in malignant pleural effusions secondary to mesothelioma and carcinoma
    Peter DeLong
    Thoracic Oncology Research Laboratory, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    Cancer Biol Ther 4:342-6. 2005
    ..These results have implications for the development of immunotherapy directed to the malignant pleural space, and suggest the need to tailor immunotherapy to overcome immunosuppressive mechanisms in tumor environments...
  22. ncbi request reprint A phase I study of Foscan-mediated photodynamic therapy and surgery in patients with mesothelioma
    Joseph S Friedberg
    Department of Surgery, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania 19104 4283, USA
    Ann Thorac Surg 75:952-9. 2003
    ..The purpose of the study was to define the toxicities and to determine the maximally tolerated dose (MTD) of Foscan-mediated PDT...
  23. ncbi request reprint Suramin inhibits the growth of malignant mesothelioma in vitro, and in vivo, in murine flank and intraperitoneal models
    Judith W Cook
    Section of Thoracic Surgery, Division of Cardiothoracic Surgery, Department of Surgery, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Lung Cancer 42:263-74. 2003
    ..These studies demonstrate that suramin may have the potential to provide effective therapy for MM, and that further studies are necessary to elucidate the survival advantage of suramin mediated MM growth inhibition...
  24. ncbi request reprint Transbronchial needle injection: a systematic review of a new diagnostic and therapeutic paradigm
    Christopher W Seymour
    Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA 19104 4283, USA
    Respiration 73:78-89. 2006
    ..Transbronchial needle catheters are commonly used during flexible and rigid bronchoscopy for needle aspiration. The use of these catheters can be expanded by employing the technique of transbronchial needle injection...
  25. ncbi request reprint Blockade of TNF-alpha decreases both inflammation and efficacy of intrapulmonary Ad.IFNbeta immunotherapy in an orthotopic model of bronchogenic lung cancer
    Michael J Wilderman
    Thoracic Oncology Research Laboratory, University of Pennsylvania Medical Center, BRB II III, 421 Curie Boulevard, Philadelphia, PA 19104 6160, USA
    Mol Ther 13:910-7. 2006
    ..Therapeutic application of anti-inflammatory therapy in immuno-gene therapy strategies should thus be undertaken with caution...
  26. ncbi request reprint Bronchial anastomotic stricutre caused by ossification of an intercostal muscle flap
    M E Deeb
    Department of Surgery, University of Pennsylvania Medical Center, Philadelphia 19104, USA
    Ann Thorac Surg 71:1700-2. 2001
    ..Stent insertion failed, and the patient ultimately required completion pneumonectomy. We recommended that caution be used when wrapping intercostal muscle around any important lumen...
  27. ncbi request reprint Use of an implantable pleural catheter for trapped lung syndrome in patients with malignant pleural effusion
    G W Pien
    Pulmonary, Allergy and Critical Care Division, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, USA
    Chest 119:1641-6. 2001
    ..Our patients reported good symptomatic relief following catheter placement with few major complications...
  28. ncbi request reprint Cardiopulmonary bypass for bilateral sequential lung transplantation in patients with chronic obstructive pulmonary disease without adverse effect on lung function or clinical outcome
    Wilson Y Szeto
    Department of Surgery, Division of Cardiothoracic Surgery, Hospital of the University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA
    J Thorac Cardiovasc Surg 124:241-9. 2002
    ....
  29. ncbi request reprint Bronchial sleeve resection for posttransplant stricture
    E Carter Paulson
    Section of Thoracic Surgery, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Ann Thorac Surg 76:2075-6. 2003
    ..All attempts at conservative management failed, and the stricture was successfully treated by a parenchymal-sparing segmental sleeve resection. Although rare, this is an important technique in the management of this difficult problem...
  30. ncbi request reprint Detection of SV40 DNA sequences in malignant mesothelioma specimens from the United States, but not from Turkey
    Assunta De Rienzo
    Human Genetics Program, Fox Chase Cancer Center, 7701 Burholme Avenue, Philadelphia, PA 19111, USA
    J Cell Biochem 84:455-9. 2002
    ..We detected SV40 sequences in 4 of 11 specimens from the United States, but in none of the 9 Turkish samples examined. These findings suggest that geographical differences exist with regard to the involvement of SV40 in human tumors...
  31. ncbi request reprint Malignant pleural effusions: management options with consideration of coding, billing, and a decision approach
    Andrew R Haas
    Interventional Pulmonary Program, Jefferson Medical College of Thomas Jefferson University, Pulmonary and Critical Care Medicine, 834 Walnut St, Sixth Floor, Philadelphia, PA 19107, USA
    Chest 132:1036-41. 2007
    ..This article will provide a general review of MPE management strategies including information concerning coding, billing, documentation, and a decision approach among these various methods...
  32. ncbi request reprint Tumors of the mediastinum
    Beau V Duwe
    Department of Internal Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, USA
    Chest 128:2893-909. 2005
    ..This article will review the anatomy of the mediastinum as well as the different clinical, radiographic, and prognostic features, and therapeutic options of the most commonly encountered masses...
  33. ncbi request reprint EUS staging of primary lung carcinoma: are we ready for it?
    Daniel H Sterman
    Gastrointest Endosc 59:393-5. 2004
  34. ncbi request reprint A multicenter trial of an intrabronchial valve for treatment of severe emphysema
    Douglas E Wood
    Division of Cardiothoracic Surgery, The University of Washington, Seattle, Wash 98195 6310, USA
    J Thorac Cardiovasc Surg 133:65-73. 2007
    ..The Intrabronchial Valve is used to block bronchial airflow in the most emphysematous areas of lung...
  35. ncbi request reprint TNFerade to the rescue? Guidelines for evaluating phase I cancer gene transfer trials
    Steven M Albelda
    J Clin Oncol 22:577-9. 2004