Jeffery D Steketee

Summary

Affiliation: University of Tennessee
Country: USA

Publications

  1. ncbi Repeated exposure to cocaine alters the modulation of mesocorticolimbic glutamate transmission by medial prefrontal cortex Group II metabotropic glutamate receptors
    Xiaohu Xie
    Department of Pharmacology, University of Tennessee Health Science Center, Memphis, Tennessee, USA
    J Neurochem 107:186-96. 2008
  2. ncbi Neurotransmitter systems of the medial prefrontal cortex: potential role in sensitization to psychostimulants
    Jeffery D Steketee
    Department of Pharmacology, University of Tennessee Health Sciences Center, Memphis, TN 38163, USA
    Brain Res Brain Res Rev 41:203-28. 2003
  3. ncbi Repeated exposure to cocaine alters medial prefrontal cortex dopamine D₂-like receptor modulation of glutamate and dopamine neurotransmission within the mesocorticolimbic system
    Kun Liu
    Department Pharmacology, University of Tennessee Health Science Center, Memphis, Tennessee, USA
    J Neurochem 119:332-41. 2011
  4. ncbi Time-dependent effects of repeated cocaine administration on dopamine transmission in the medial prefrontal cortex
    Jason M Williams
    Department of Pharmacology, University of Tennessee Health Science Center, 874 Union Avenue, Memphis, TN 38163, USA
    Neuropharmacology 48:51-61. 2005
  5. ncbi Effects of cocaine-induced behavioural sensitization on GABA transmission within rat medial prefrontal cortex
    Prathiba Jayaram
    Department of Pharmacology, University of Tennessee Health Sciences Center, 874 Union Avenue, Memphis, TN 38163, USA
    Eur J Neurosci 21:2035-9. 2005
  6. ncbi Effects of repeated cocaine on the release and clearance of dopamine within the rat medial prefrontal cortex
    Jason M Williams
    Department of Pharmacology, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
    Synapse 55:98-109. 2005
  7. ncbi Cocaine-induced increases in medial prefrontal cortical GABA transmission involves glutamatergic receptors
    Prathiba Jayaram
    Department of Pharmacology University of Tennessee Health Science Center 874 Union Avenue Room 115 Crowe Research Building Memphis, TN 38163, USA
    Eur J Pharmacol 531:74-9. 2006
  8. ncbi Effects of repeated exposure to cocaine on group II metabotropic glutamate receptor function in the rat medial prefrontal cortex: behavioral and neurochemical studies
    Xiaohu Xie
    Department of Pharmacology, University of Tennessee Health Science Center, 874 Union Avenue, Memphis, TN 38163, USA
    Psychopharmacology (Berl) 203:501-10. 2009
  9. ncbi Regulation of cocaine-induced reinstatement by group II metabotropic glutamate receptors in the ventral tegmental area
    Lianyi Lu
    Department of Pharmacology, University of Tennessee Health Science Center, 874 Union Avenue, Crowe 115, Memphis, TN 38163, USA
    Psychopharmacology (Berl) 220:75-85. 2012
  10. ncbi Cortical mechanisms of cocaine sensitization
    Jeffery D Steketee
    Department of Pharmacology, University of Tennessee Health Science Center, Memphis, TN 38163, USA
    Crit Rev Neurobiol 17:69-86. 2005

Collaborators

Detail Information

Publications23

  1. ncbi Repeated exposure to cocaine alters the modulation of mesocorticolimbic glutamate transmission by medial prefrontal cortex Group II metabotropic glutamate receptors
    Xiaohu Xie
    Department of Pharmacology, University of Tennessee Health Science Center, Memphis, Tennessee, USA
    J Neurochem 107:186-96. 2008
    ....
  2. ncbi Neurotransmitter systems of the medial prefrontal cortex: potential role in sensitization to psychostimulants
    Jeffery D Steketee
    Department of Pharmacology, University of Tennessee Health Sciences Center, Memphis, TN 38163, USA
    Brain Res Brain Res Rev 41:203-28. 2003
    ..Finally a model of the mPFC that may be useful in directing future research efforts on the cortical mechanisms involved in the development of sensitization will be proposed...
  3. ncbi Repeated exposure to cocaine alters medial prefrontal cortex dopamine D₂-like receptor modulation of glutamate and dopamine neurotransmission within the mesocorticolimbic system
    Kun Liu
    Department Pharmacology, University of Tennessee Health Science Center, Memphis, Tennessee, USA
    J Neurochem 119:332-41. 2011
    ..These findings indicate that the expression of sensitization to cocaine is associated with altered modulation of mesocorticolimbic glutamatergic transmission at the level of the medial prefrontal cortex...
  4. ncbi Time-dependent effects of repeated cocaine administration on dopamine transmission in the medial prefrontal cortex
    Jason M Williams
    Department of Pharmacology, University of Tennessee Health Science Center, 874 Union Avenue, Memphis, TN 38163, USA
    Neuropharmacology 48:51-61. 2005
    ..These data suggest that repeated cocaine produces temporally distinct behavioral effects associated with alterations in mPFC DA responsiveness to cocaine that may be involved in the development of behavioral sensitization...
  5. ncbi Effects of cocaine-induced behavioural sensitization on GABA transmission within rat medial prefrontal cortex
    Prathiba Jayaram
    Department of Pharmacology, University of Tennessee Health Sciences Center, 874 Union Avenue, Memphis, TN 38163, USA
    Eur J Neurosci 21:2035-9. 2005
    ..These data suggest that cocaine-induced sensitization is associated with a transient increase in mPFC GABA transmission...
  6. ncbi Effects of repeated cocaine on the release and clearance of dopamine within the rat medial prefrontal cortex
    Jason M Williams
    Department of Pharmacology, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
    Synapse 55:98-109. 2005
    ..The relevance of these findings is discussed in relation to mPFC involvement in psychostimulant sensitization...
  7. ncbi Cocaine-induced increases in medial prefrontal cortical GABA transmission involves glutamatergic receptors
    Prathiba Jayaram
    Department of Pharmacology University of Tennessee Health Science Center 874 Union Avenue Room 115 Crowe Research Building Memphis, TN 38163, USA
    Eur J Pharmacol 531:74-9. 2006
    ..These data indicate that enhanced medial prefrontal cortex GABA transmission seen in cocaine-sensitized animals involves glutamatergic stimulation of AMPA receptors...
  8. ncbi Effects of repeated exposure to cocaine on group II metabotropic glutamate receptor function in the rat medial prefrontal cortex: behavioral and neurochemical studies
    Xiaohu Xie
    Department of Pharmacology, University of Tennessee Health Science Center, 874 Union Avenue, Memphis, TN 38163, USA
    Psychopharmacology (Berl) 203:501-10. 2009
    ..Enhanced excitatory output from the medial prefrontal cortex (mPFC), which can be modulated by group II metabotropic glutamate receptors (mGluR), is thought to play a key role in the development of sensitization to cocaine...
  9. ncbi Regulation of cocaine-induced reinstatement by group II metabotropic glutamate receptors in the ventral tegmental area
    Lianyi Lu
    Department of Pharmacology, University of Tennessee Health Science Center, 874 Union Avenue, Crowe 115, Memphis, TN 38163, USA
    Psychopharmacology (Berl) 220:75-85. 2012
    ..Recent studies have shown that drugs of abuse enhance glutamate neurotransmission in dopamine neurons in the ventral tegmental area (VTA) and such enhancement may contribute to the risk of relapse...
  10. ncbi Cortical mechanisms of cocaine sensitization
    Jeffery D Steketee
    Department of Pharmacology, University of Tennessee Health Science Center, Memphis, TN 38163, USA
    Crit Rev Neurobiol 17:69-86. 2005
    ..A model will be presented that may serve to direct future studies on the involvement of the mPFC in the development of cocaine sensitization, which ultimately could lead to development of pharmacotherapies for cocaine addiction...
  11. ncbi Injections of baclofen into the ventral medial prefrontal cortex block the initiation, but not the expression, of cocaine sensitization in rats
    Jeffery D Steketee
    Department of Pharmacology, University of Tennessee Health Science Center, 874 Union Avenue Room 115 Crowe, Memphis, TN 38163, USA
    Psychopharmacology (Berl) 180:352-8. 2005
    ..Increased excitatory output from the medial prefrontal cortex (mPFC) is thought to play a key role in the development of sensitization to cocaine. Gamma-aminobutyric acid (GABA) inhibits this excitatory output...
  12. ncbi Repeated injections of sulpiride into the medial prefrontal cortex induces sensitization to cocaine in rats
    Jeffery D Steketee
    Department of Pharmacology, University of Tennessee Health Science Center, 874 Union Avenue Room 115 Crowe, Memphis, TN 38163, USA
    Psychopharmacology (Berl) 179:753-60. 2005
    ..The present study was designed to further examine the involvement of mPFC dopamine D(2) receptors in cocaine sensitization...
  13. ncbi Examination of a role for metabotropic glutamate receptor 5 in the medial prefrontal cortex in cocaine sensitization in rats
    Kristin M Timmer
    Department of Pharmacology, University of Tennessee Health Science Center, 874 Union Ave, Rm 115 Crowe, Memphis, TN 38163, USA
    Psychopharmacology (Berl) 221:91-100. 2012
    ....
  14. ncbi Cocaine increases medial prefrontal cortical glutamate overflow in cocaine-sensitized rats: a time course study
    Jason M Williams
    Department of Pharmacology, University of Tennessee Health Science Center, 874 Union Avenue, Memphis, TN 38163, USA
    Eur J Neurosci 20:1639-46. 2004
    ....
  15. ncbi Activation of D₂-like receptors in rat ventral tegmental area inhibits cocaine-reinstated drug-seeking behavior
    Yueqiang Xue
    Department of Pharmacology, University of Tennessee Health Science Center, Memphis, TN 38163, USA
    Eur J Neurosci 33:1291-8. 2011
    ..The role of potential changes in D₂-like receptors and related signaling molecules of dopamine neurons in the vulnerability to relapse was discussed...
  16. ncbi Upregulation of ionotropic glutamate receptor subunits within specific mesocorticolimbic regions during chronic nicotine self-administration
    Fan Wang
    Department of Pharmacology, University of Tennessee Health Science Center, Memphis, TN 38163, USA
    Neuropsychopharmacology 32:103-9. 2007
    ..These findings suggest that chronic nicotine SA selectively increased the levels of ionotropic glutamate receptor subunits in a brain region-specific manner...
  17. ncbi Inactivation of the central nucleus of the amygdala reduces the effect of punishment on cocaine self-administration in rats
    Yueqiang Xue
    Department of Pharmacology, University of Tennessee Health Science Center, 874 Union Avenue, Crowe 115, Memphis, TN 38163, USA
    Eur J Neurosci 35:775-83. 2012
    ..Rats with a history of extended cocaine SA appeared to be less sensitive to punishment. The decreased sensitivity could result from the neuroplastic changes induced by extended cocaine SA in the CeN...
  18. ncbi Regulation of cocaine-reinstated drug-seeking behavior by kappa-opioid receptors in the ventral tegmental area of rats
    WenLin Sun
    Department of Pharmacology, University of Tennessee Health Science Center, 874 Union Avenue, Crowe 115, Memphis, TN 38163, USA
    Psychopharmacology (Berl) 210:179-88. 2010
    ..Relapse is one of the main challenges facing the current treatment of cocaine addiction. Understanding its neurobiological mechanism is a critical step toward developing effective anti-relapse therapies...
  19. ncbi Effects of repeated inhalation of toluene on ionotropic GABA A and glutamate receptor subunit levels in rat brain
    Jason M Williams
    Department of Pharmacology, University of Tennessee Health Science Center, Memphis, TN 38163, USA
    Neurochem Int 46:1-10. 2005
    ..These studies show that toluene differentially alters the levels of specific GABAergic and glutamatergic receptor subunits in a regionally selective manner...
  20. ncbi Drug wanting: behavioral sensitization and relapse to drug-seeking behavior
    Jeffery D Steketee
    Department of Pharmacology, University of Tennessee Health Science Center, 874 Union Avenue, Memphis, TN 38163, USA
    Pharmacol Rev 63:348-65. 2011
    ....
  21. ncbi Effects of repeated cocaine on medial prefrontal cortical GABAB receptor modulation of neurotransmission in the mesocorticolimbic dopamine system
    Prathiba Jayaram
    Department of Pharmacology, University of Tennessee Health Sciences Center, Memphis, Tennessee 38163, USA
    J Neurochem 90:839-47. 2004
    ..The data suggest that alterations in GABAB receptor modulation of medial prefrontal cortical excitatory output may play an important role in the development of sensitization to cocaine...
  22. ncbi Characterization of dopamine transport in crude synaptosomes prepared from rat medial prefrontal cortex
    Jason M Williams
    Department of Pharmacology, University of Tennessee Health Science Center, 874 Union Avenue, Memphis, TN 38163, USA
    J Neurosci Methods 137:161-5. 2004
    ..The described assay conditions would be useful in examining DA uptake within specific brain regions obtained from a single animal...
  23. ncbi Cocaine sensitization: modulation by dopamine D2 receptors
    Chad E Beyer
    Department of Pharmacology and Therapeutics and School of Graduate Studies, Louisiana State University Health Sciences Center, Shreveport, LA 71130-3932, USA
    Cereb Cortex 12:526-35. 2002
    ..Collectively, the results show that activation of D(2)-like receptors in the mPFC may alter the enduring changes responsible for the development of cocaine sensitization...