Research Topics
| Martin SteinhoffSummaryAffiliation: University of California Country: USA Publications
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Detail Information
Publications
IL-33: a novel danger signal system in atopic dermatitisFerda Cevikbas
Department of Dermatology and Surgery, University of California, San Francisco, San Francisco, California 94143, USA
J Invest Dermatol 132:1326-9. 2012..On the other hand, several studies have reported on the inhibitory effects of sST2 in inflammatory and fibrotic diseases, suggesting that IL-33/ST2 is a unique cytokine with potential pro- and anti-inflammatory effects...
Pruritus: management algorithms and experimental therapiesMartin Steinhoff
Department of Surgery, University of California San Francisco, San Francisco, CA 94143, USA
Semin Cutan Med Surg 30:127-37. 2011..Finally, we summarize current exciting developments of experimental strategies in itch research and in clinical development for itch therapy...
Role of spinal neurotransmitter receptors in itch: new insights into therapies and drug developmentFerda Cevikbas
Department of Dermatology, University of California, San Francisco, CA 94143 0660, USA
CNS Neurosci Ther 17:742-9. 2011..Thus, the identification of itch-specific receptors and understanding itch-related circuits in the spinal cord may be innovative strategies for the development of novel antipruritic drugs...
"Outside-to-inside" (and now back to "outside") pathogenic mechanisms in atopic dermatitisPeter M Elias
Dermatology Service, Veterans Affairs Medical Center, and Department of Dermatology, University of California, San Francisco, California 94121, USA
J Invest Dermatol 128:1067-70. 2008..This cycle comprises an "outside-inside-outside" model of AD pathogenesis (Elias et al., in press)...
Mouse model of touch-evoked itch (alloknesis)Tasuku Akiyama
Department of Neurobiology, Physiology, and Behavior, University of California, Davis, Davis, California, USA
J Invest Dermatol 132:1886-91. 2012..In mice with experimental dry skin, there was a time-dependent increase in spontaneous and touch-evoked scratching. This animal model appears to be useful to investigate neural mechanisms of itch and alloknesis...
Management of itch in atopic dermatitisJudith Hong
Department of Dermatology, University of California San Francisco, San Francisco, CA 94143, USA
Semin Cutan Med Surg 30:71-86. 2011..This review highlights various topical, systemic, and complementary and alternative therapies, as well as provide a therapeutic ladder for optimized long-term control of itch in atopic dermatitis...
Pruritus and renal failureTimothy G Berger
Department of Dermatology, University of California San Francisco, San Francisco, CA 94143, USA
Semin Cutan Med Surg 30:99-100. 2011..Gabapentin has been recently discovered as an effective agent for the patient with ESRD pruritus. Kappa opiate agonists are promising new therapeutic options...
Anatomy and neurophysiology of pruritusAkihiko Ikoma
Department of Dermatology and Surgery, University of California, San Francisco, San Francisco, CA, USA
Semin Cutan Med Surg 30:64-70. 2011..Itch sensitization must also be considered in discussions of itch. This review highlights anatomical and functional properties of itch pathways and their relation to understanding itch perception and pruritic diseases...
Proteinase-activated receptors 1 and 2 regulate invasive behavior of human melanoma cells via activation of protein kinase D1Cordula Kempkes
Department of Dermatology and IZKF Münster, University of Munster, Munster, Germany
J Invest Dermatol 132:375-84. 2012..Inactivation of the PKD1 pathway may be beneficial for the inhibition of PAR-induced melanoma proliferation and for maintenance of the inflammatory tumor environment...
Clinical, cellular, and molecular aspects in the pathophysiology of rosaceaMartin Steinhoff
Departments of Dermatology and Surgery, University of California, San Francisco, San Francisco, California, USA
J Investig Dermatol Symp Proc 15:2-11. 2011..This review highlights recent molecular (gene array) and cellular findings and aims to integrate the different body defense mechanisms into a modern concept of rosacea pathophysiology...
Innovative management of pruritusJamison D Feramisco
Department of Dermatology, University of California at San Francisco, 1701 Divisadero Street, 3rd Floor, San Francisco, CA 94115, USA
Dermatol Clin 28:467-78. 2010..They also addresses mechanisms and management modalities of itch in common systemic diseases, including cholestasis, uremia, and neuropathic dysfunction...
Pruritus in elderly patients--eruptions of senescenceTimothy G Berger
Department of Dermatology, University of California San Francisco, San Francisco, CA 94143, USA
Semin Cutan Med Surg 30:113-7. 2011....
Psychoneuroimmunology of psychological stress and atopic dermatitis: pathophysiologic and therapeutic updatesAndrea L Suarez
Department of Dermatology, University of Colorado Denver, School of Medicine, Aurora, USA
Acta Derm Venereol 92:7-15. 2012....
