Tim Starr

Summary

Affiliation: University of Minnesota
Country: USA

Publications

  1. ncbi request reprint Positive and negative selection of T cells
    Timothy K Starr
    Center for Immunology and the Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis 55455, USA
    Annu Rev Immunol 21:139-76. 2003
  2. pmc A transposon-based genetic screen in mice identifies genes altered in colorectal cancer
    Timothy K Starr
    Department of Genetics, Cell Biology and Development, Center for Genome Engineering, Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA
    Science 323:1747-50. 2009
  3. pmc A Sleeping Beauty transposon-mediated screen identifies murine susceptibility genes for adenomatous polyposis coli (Apc)-dependent intestinal tumorigenesis
    Timothy K Starr
    Department of Genetics, Cell Biology and Development, Center for Genome Engineering, Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA
    Proc Natl Acad Sci U S A 108:5765-70. 2011
  4. pmc Large-scale integrative network-based analysis identifies common pathways disrupted by copy number alterations across cancers
    Tae Hyun Hwang
    Masonic Cancer Center, University of Minnesota Twin Cities, Minneapolis, MN, USA
    BMC Genomics 14:440. 2013
  5. pmc TAPDANCE: an automated tool to identify and annotate transposon insertion CISs and associations between CISs from next generation sequence data
    Aaron L Sarver
    Biostatistics and Bioinformatics Masonic Cancer Center, University of Minnesota, Minneapolis, USA
    BMC Bioinformatics 13:154. 2012

Collaborators

Detail Information

Publications5

  1. ncbi request reprint Positive and negative selection of T cells
    Timothy K Starr
    Center for Immunology and the Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis 55455, USA
    Annu Rev Immunol 21:139-76. 2003
    ..We also discuss emerging data on the selection of regulatory T cells. Such cells require a high-affinity interaction with self-antigens, yet differentiate into regulatory cells instead of being eliminated...
  2. pmc A transposon-based genetic screen in mice identifies genes altered in colorectal cancer
    Timothy K Starr
    Department of Genetics, Cell Biology and Development, Center for Genome Engineering, Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA
    Science 323:1747-50. 2009
    ..These genes include APC, PTEN, and SMAD4. The screen also identified 17 candidate genes that had not previously been implicated in CRC, including POLI, PTPRK, and RSPO2...
  3. pmc A Sleeping Beauty transposon-mediated screen identifies murine susceptibility genes for adenomatous polyposis coli (Apc)-dependent intestinal tumorigenesis
    Timothy K Starr
    Department of Genetics, Cell Biology and Development, Center for Genome Engineering, Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA
    Proc Natl Acad Sci U S A 108:5765-70. 2011
    ..These findings demonstrate the utility of using transposon mutagenesis to identify low-frequency and cooperating cancer genes; this approach will aid in the development of combinatorial therapies targeting this deadly disease...
  4. pmc Large-scale integrative network-based analysis identifies common pathways disrupted by copy number alterations across cancers
    Tae Hyun Hwang
    Masonic Cancer Center, University of Minnesota Twin Cities, Minneapolis, MN, USA
    BMC Genomics 14:440. 2013
    ....
  5. pmc TAPDANCE: an automated tool to identify and annotate transposon insertion CISs and associations between CISs from next generation sequence data
    Aaron L Sarver
    Biostatistics and Bioinformatics Masonic Cancer Center, University of Minnesota, Minneapolis, USA
    BMC Bioinformatics 13:154. 2012
    ..Previous approaches applied to this problem also required significant manual annotation...