William Stanley

Summary

Affiliation: University of Maryland
Country: USA

Publications

  1. ncbi Effects of glucose-6-phosphate dehydrogenase deficiency on the metabolic and cardiac responses to obesogenic or high-fructose diets
    Peter A Hecker
    Division of Cardiology, Department of Medicine, University of Maryland, Baltimore, Maryland 21201, USA
    Am J Physiol Endocrinol Metab 303:E959-72. 2012
  2. ncbi Update on lipids and mitochondrial function: impact of dietary n-3 polyunsaturated fatty acids
    William C Stanley
    Division of Cardiology, Department of Medicine, University of Maryland, Baltimore, Maryland 21201, USA
    Curr Opin Clin Nutr Metab Care 15:122-6. 2012
  3. ncbi Dietary fat and heart failure: moving from lipotoxicity to lipoprotection
    William C Stanley
    Division of Cardiology, Department of Medicine, University of Maryland, Baltimore, MD 21201, USA
    Circ Res 110:764-76. 2012
  4. ncbi ω-3 Polyunsaturated fatty acids prevent pressure overload-induced ventricular dilation and decrease in mitochondrial enzymes despite no change in adiponectin
    Karen M O'Shea
    Division of Cardiology and Department of Medicine, University of Maryland, Baltimore, MD, USA
    Lipids Health Dis 9:95. 2010
  5. ncbi Lipotoxicity and the development of heart failure: moving from mouse to man
    William C Stanley
    Division of Cardiology, Department of Medicine, University of Maryland, Baltimore, MD 21201, USA
    Cell Metab 12:555-6. 2010
  6. ncbi Effects of adiponectin deficiency on structural and metabolic remodeling in mice subjected to pressure overload
    Karen M O'Shea
    Division of Cardiology, Dept of Medicine, Univ of Maryland Baltimore, 20 Penn St, HSF2, Rm S022, Baltimore, MD 21201, USA
    Am J Physiol Heart Circ Physiol 298:H1639-45. 2010

Research Grants

  1. CARDIAC ENERGY METABOLISM IN HEART FAILURE
    William Stanley; Fiscal Year: 2005
  2. CARDIAC ENERGY METABOLISM IN HEART FAILURE
    William Stanley; Fiscal Year: 2003
  3. REGULATION OF CARDIAC SUBSTRATE METABOLISM DURING STRESS
    William Stanley; Fiscal Year: 2001

Collaborators

  • Christine Des Rosiers
  • Kenneth Walsh
  • Peter A Hecker
  • Karen M O'Shea
  • David J Chess
  • Ramzi J Khairallah
  • Charlene P Kimar
  • M Faadiel Essop
  • Rudo F Mapanga
  • James W Cox
  • Bethany H Brown
  • Rogerio F Ribeiro
  • Kadambari C Shekar
  • Girma Asemu
  • Kelly A O'Connell
  • Sharad Rastogi
  • Hani N Sabbah
  • Biao Lei

Detail Information

Publications6

  1. ncbi Effects of glucose-6-phosphate dehydrogenase deficiency on the metabolic and cardiac responses to obesogenic or high-fructose diets
    Peter A Hecker
    Division of Cardiology, Department of Medicine, University of Maryland, Baltimore, Maryland 21201, USA
    Am J Physiol Endocrinol Metab 303:E959-72. 2012
    ..On the other hand, it modestly suppressed indexes of glucose flux into nonoxidative pathways in myocardium, suggesting potential protective effects...
  2. ncbi Update on lipids and mitochondrial function: impact of dietary n-3 polyunsaturated fatty acids
    William C Stanley
    Division of Cardiology, Department of Medicine, University of Maryland, Baltimore, Maryland 21201, USA
    Curr Opin Clin Nutr Metab Care 15:122-6. 2012
    ..In the present review, we examine the novel effects of n-3 PUFA on mitochondria, with an emphasis on cardiac mitochondrial phospholipids...
  3. ncbi Dietary fat and heart failure: moving from lipotoxicity to lipoprotection
    William C Stanley
    Division of Cardiology, Department of Medicine, University of Maryland, Baltimore, MD 21201, USA
    Circ Res 110:764-76. 2012
    ..Additional clinical and animals studies are needed to determine the optimal diet in terms of saturated, monounsaturated, and n-6 polyunsaturated fatty acids intake for this vulnerable patient population...
  4. ncbi ω-3 Polyunsaturated fatty acids prevent pressure overload-induced ventricular dilation and decrease in mitochondrial enzymes despite no change in adiponectin
    Karen M O'Shea
    Division of Cardiology and Department of Medicine, University of Maryland, Baltimore, MD, USA
    Lipids Health Dis 9:95. 2010
    ..This study 1) assessed the effects of ω-3 PUFA on LV dilation and down-regulation of mitochondrial enzymes in response to pressure overload; and 2) evaluated the role of adiponectin in mediating the effects of ω-3 PUFA in heart...
  5. ncbi Lipotoxicity and the development of heart failure: moving from mouse to man
    William C Stanley
    Division of Cardiology, Department of Medicine, University of Maryland, Baltimore, MD 21201, USA
    Cell Metab 12:555-6. 2010
    ..Overexpressing PPARγ on a PPARα-/- background improved cardiac function, suggesting that specific lipid metabolites and lipid packaging determine cardiac lipotoxicity...
  6. ncbi Effects of adiponectin deficiency on structural and metabolic remodeling in mice subjected to pressure overload
    Karen M O'Shea
    Division of Cardiology, Dept of Medicine, Univ of Maryland Baltimore, 20 Penn St, HSF2, Rm S022, Baltimore, MD 21201, USA
    Am J Physiol Heart Circ Physiol 298:H1639-45. 2010
    ....

Research Grants11

  1. CARDIAC ENERGY METABOLISM IN HEART FAILURE
    William Stanley; Fiscal Year: 2005
    ..The meeting is organized by the Society for Heart and Vascular Metabolism, a not-for-profit educational corporation with an established record for organizing successful meetings related to metabolism and heart disease. ..
  2. CARDIAC ENERGY METABOLISM IN HEART FAILURE
    William Stanley; Fiscal Year: 2003
    ..3) Determine if there is improved cardiac function in the failing heart when CPT-I activity and the rate of fatty acid oxidation are inhibited either acutely or for 12 weeks. ..
  3. REGULATION OF CARDIAC SUBSTRATE METABOLISM DURING STRESS
    William Stanley; Fiscal Year: 2001
    ..3) Determine if the impaired contractile function and pyruvate oxidation is post-ischemic reperfused myocardium is corrected by acute treatment with insulin in normal and streptozotocin diabetic swine. ..