J A Stanley

Summary

Affiliation: University of Pittsburgh
Country: USA

Publications

  1. ncbi request reprint Postprocessing method to segregate and quantify the broad components underlying the phosphodiester spectral region of in vivo (31)P brain spectra
    J A Stanley
    Neurophysics Laboratory, Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    Magn Reson Med 45:390-6. 2001
  2. ncbi request reprint In vivo magnetic resonance spectroscopy and its application to neuropsychiatric disorders
    Jeffrey A Stanley
    Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
    Can J Psychiatry 47:315-26. 2002
  3. ncbi request reprint Metabolic alterations in postmortem Alzheimer's disease brain are exaggerated by Apo-E4
    W E Klunk
    Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, PA 15261, USA
    Neurobiol Aging 19:511-5. 1998
  4. ncbi request reprint Prefrontal membrane phospholipid metabolism of child and adolescent offspring at risk for schizophrenia or schizoaffective disorder: an in vivo 31P MRS study
    M S Keshavan
    Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, PA 15213, USA
    Mol Psychiatry 8:316-23, 251. 2003
  5. ncbi request reprint Molecular insights into neurodevelopmental and neurodegenerative diseases
    J W Pettegrew
    Department of Psychiatry, School of Medicine, Neurophysics Laboratory, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Brain Res Bull 53:455-69. 2000
  6. ncbi request reprint Reduced NAA levels in the dorsolateral prefrontal cortex of young bipolar patients
    Roberto B Sassi
    Division of Mood and Anxiety Disorders, Associate Professor of Psychiatry and Radiology, Krus Endowed Chair in Psychiatry, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229 3900, USA
    Am J Psychiatry 162:2109-15. 2005
  7. ncbi request reprint Abnormal cellular energy and phospholipid metabolism in the left dorsolateral prefrontal cortex of medication-free individuals with bipolar disorder: an in vivo 1H MRS study
    Benicio N Frey
    MOOD CNS Program, Division of Mood and Anxiety Disorders, Department of Psychiatry, The University of Texas Health Science Center at San Antonio, TX 78229, USA
    Bipolar Disord 9:119-27. 2007
  8. ncbi request reprint Low levels of N-acetyl aspartate in the left dorsolateral prefrontal cortex of pediatric bipolar patients
    Rene L Olvera
    Division of Child and Adolescent Psychiatry, Department of Psychiatry, The University of Texas Health Science Center at San Antonio, San Antonio, Texas
    J Child Adolesc Psychopharmacol 17:461-73. 2007
  9. ncbi request reprint Brain-derived neurotrophic factor val66met polymorphism affects prefrontal energy metabolism in bipolar disorder
    Benicio N Frey
    Department of Psychiatry, Psychiatric Genetics Research Center, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA
    Neuroreport 18:1567-70. 2007
  10. ncbi request reprint Proton spectroscopy study of the left dorsolateral prefrontal cortex in pediatric depressed patients
    Sheila C Caetano
    Division of Mood and Anxiety Disorders, Department of Psychiatry, The University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229, USA
    Neurosci Lett 384:321-6. 2005

Detail Information

Publications19

  1. ncbi request reprint Postprocessing method to segregate and quantify the broad components underlying the phosphodiester spectral region of in vivo (31)P brain spectra
    J A Stanley
    Neurophysics Laboratory, Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    Magn Reson Med 45:390-6. 2001
    ..The ability to segregate and quantify these various PME and PDE contributions provides additional spectral information and improves the accuracy of the interpretation of (31)P spectroscopy results. Magn Reson Med 45:390-396, 2001...
  2. ncbi request reprint In vivo magnetic resonance spectroscopy and its application to neuropsychiatric disorders
    Jeffrey A Stanley
    Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
    Can J Psychiatry 47:315-26. 2002
    ..These findings are consistent with developmental alterations in the temporal lobe and in the cerebellum of persons with autism. This paper discusses recent findings of new functions of N-acetylaspartate...
  3. ncbi request reprint Metabolic alterations in postmortem Alzheimer's disease brain are exaggerated by Apo-E4
    W E Klunk
    Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, PA 15261, USA
    Neurobiol Aging 19:511-5. 1998
    ..The decrease in N-acetyl-L-aspartate (NAA) was also exaggerated. These results suggest membrane phospholipid metabolite alterations observed in AD are more severe in the presence of the Apo-E4 allele...
  4. ncbi request reprint Prefrontal membrane phospholipid metabolism of child and adolescent offspring at risk for schizophrenia or schizoaffective disorder: an in vivo 31P MRS study
    M S Keshavan
    Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, PA 15213, USA
    Mol Psychiatry 8:316-23, 251. 2003
    ..Follow-up studies are needed to examine the predictive value of these measures for future emergence of schizophrenia in at-risk individuals...
  5. ncbi request reprint Molecular insights into neurodevelopmental and neurodegenerative diseases
    J W Pettegrew
    Department of Psychiatry, School of Medicine, Neurophysics Laboratory, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Brain Res Bull 53:455-69. 2000
    ....
  6. ncbi request reprint Reduced NAA levels in the dorsolateral prefrontal cortex of young bipolar patients
    Roberto B Sassi
    Division of Mood and Anxiety Disorders, Associate Professor of Psychiatry and Radiology, Krus Endowed Chair in Psychiatry, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229 3900, USA
    Am J Psychiatry 162:2109-15. 2005
    ..In order to examine whether such abnormalities would also be found in younger patients, a 1H spectroscopy study was conducted that focused on the dorsolateral prefrontal cortex of children and adolescents with bipolar disorder...
  7. ncbi request reprint Abnormal cellular energy and phospholipid metabolism in the left dorsolateral prefrontal cortex of medication-free individuals with bipolar disorder: an in vivo 1H MRS study
    Benicio N Frey
    MOOD CNS Program, Division of Mood and Anxiety Disorders, Department of Psychiatry, The University of Texas Health Science Center at San Antonio, TX 78229, USA
    Bipolar Disord 9:119-27. 2007
    ..We hypothesized that BD subjects would present abnormal cellular metabolism within the DLPFC, as reflected by lower N-acetyl-aspartate (NAA) and creatine + phosphocreatine (Cr + PCr)...
  8. ncbi request reprint Low levels of N-acetyl aspartate in the left dorsolateral prefrontal cortex of pediatric bipolar patients
    Rene L Olvera
    Division of Child and Adolescent Psychiatry, Department of Psychiatry, The University of Texas Health Science Center at San Antonio, San Antonio, Texas
    J Child Adolesc Psychopharmacol 17:461-73. 2007
    ....
  9. ncbi request reprint Brain-derived neurotrophic factor val66met polymorphism affects prefrontal energy metabolism in bipolar disorder
    Benicio N Frey
    Department of Psychiatry, Psychiatric Genetics Research Center, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA
    Neuroreport 18:1567-70. 2007
    ..These results indicate that bipolar disorder met-carriers have abnormal energy metabolism in the left dorsolateral prefrontal cortex...
  10. ncbi request reprint Proton spectroscopy study of the left dorsolateral prefrontal cortex in pediatric depressed patients
    Sheila C Caetano
    Division of Mood and Anxiety Disorders, Department of Psychiatry, The University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229, USA
    Neurosci Lett 384:321-6. 2005
    ..Increased myo-inositol levels in MDD may represent a disturbed secondary messenger system. GPC + PC and myo-inositol abnormalities further demonstrate the involvement of DLPFC in pediatric MDD...
  11. ncbi request reprint 1H magnetic resonance spectroscopy investigation of the dorsolateral prefrontal cortex in bipolar disorder patients
    Paolo Brambilla
    Division of Mood and Anxiety Disorders, Department of Psychiatry, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA
    J Affect Disord 86:61-7. 2005
    ..Furthermore, recent MRS reports suggested possible lithium-induced increase in NAA levels in bipolar patients. We examined with in vivo (1)H MRS NAA levels in the DLPFC of adult bipolar patients...
  12. ncbi request reprint 1H Magnetic resonance spectroscopy study of dorsolateral prefrontal cortex in unipolar mood disorder patients
    Paolo Brambilla
    Department of Psychiatry, Division of Mood and Anxiety Disorders, University of Texas Health Sciences Center at San Antonio, San Antonio, TX, USA
    Psychiatry Res 138:131-9. 2005
    ..Future 1H MRS investigations should longitudinally examine the role of illness chronicity on DLPFC abnormalities and their relationship with the symptoms of unipolar disorder...
  13. ncbi request reprint A proton magnetic resonance spectroscopy investigation of the dorsolateral prefrontal cortex in acute mania
    Benicio N Frey
    Laboratorio de Psiquiatría Experimental, Hospital de Clinicas de Porto Alegre, Porto Alegre, Brasil
    Hum Psychopharmacol 20:133-9. 2005
    ..N-acetyl-L-aspartate (NAA), choline-containing molecules (Cho), creatine plus phosphocreatine (Cr) and myoinositol (Ino) were measured...
  14. ncbi request reprint Correlations between peripheral polyunsaturated fatty acid content and in vivo membrane phospholipid metabolites
    Jeffrey K Yao
    Neurochemistry and Psychopharmacology Laboratory, VA Pittsburgh Healthcare System, Building 13, 7180 Highland Drive, Pittsburgh, PA 15206, USA
    Biol Psychiatry 52:823-30. 2002
    ..To address this question we examined the relations between red blood cell polyunsaturated fatty acids and brain phospholipid metabolites from different regions of interest in schizophrenia and healthy subjects...
  15. ncbi request reprint 31P-MRS study of acetyl-L-carnitine treatment in geriatric depression: preliminary results
    Jay W Pettegrew
    Neurophysics Laboratory, Department of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Bipolar Disord 4:61-6. 2002
    ....
  16. pmc An MRI and proton spectroscopy study of the thalamus in children with autism
    Antonio Y Hardan
    Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA
    Psychiatry Res 163:97-105. 2008
    ..Further investigations of this structure are warranted, since it plays an important role in information processing as part of the cortico-thalamo-cortical pathways...
  17. ncbi request reprint Regionally specific alterations in membrane phospholipids in children with ADHD: An in vivo 31P spectroscopy study
    Jeffrey A Stanley
    Department of Psychiatry and Behavioral Neurosciences, Wayne State University School of Medicine, University Health Center 9B 28, 4201 St Antoine Street, Detroit, MI 48201, USA
    Psychiatry Res 148:217-21. 2006
    ..No differences were noted in the ST. These deficits in membrane phospholipid (MPL) precursor levels suggest reduced mass of cellular MPLs due to a possible underdevelopment of neuronal processes and synapses in ADHD...
  18. pmc Reduced N-acetyl-aspartate levels in schizophrenia patients with a younger onset age: a single-voxel 1H spectroscopy study
    Jeffrey A Stanley
    Psychiatry and Behavioral Neurosciences, Wayne State University School of Medicine, Detroit, MI, 48201, United States
    Schizophr Res 93:23-32. 2007
    ....
  19. ncbi request reprint 1H MRS study of dorsolateral prefrontal cortex in healthy individuals before and after lithium administration
    Paolo Brambilla
    Division of Mood and Anxiety Disorders, Department of Psychiatry, The University of Texas Health Science Center at San Antonio, San Antonio, TX, USA
    Neuropsychopharmacology 29:1918-24. 2004
    ....