Affiliation: University of Oregon
Armstrong B, Henner A, Stewart S, Stankunas K. Shh promotes direct interactions between epidermal cells and osteoblast progenitors to shape regenerated zebrafish bone. Development. 2017;144:1165-1176 pubmed publisher
..Progressively separated pObs pools then continue regenerating independently to collectively re-form a now branched skeletal structure. ..
Akerberg B, Sarangam M, Stankunas K. Endocardial Brg1 disruption illustrates the developmental origins of semilunar valve disease. Dev Biol. 2015;407:158-72 pubmed publisher
..Mechanistic studies of SLV disease genes should distinguish between disease origins and progression; the latter may reflect secondary responses to a disrupted developmental system. ..
Bosada F, Devasthali V, Jones K, Stankunas K. Wnt/Î²-catenin signaling enables developmental transitions during valvulogenesis. Development. 2016;143:1041-54 pubmed publisher
..Disruption of these Wnt/Î²-catenin signaling roles that enable developmental transitions during valvulogenesis could account for common congenital valve defects. ..
Akerberg A, Henner A, Stewart S, Stankunas K. Histone demethylases Kdm6ba and Kdm6bb redundantly promote cardiomyocyte proliferation during zebrafish heart ventricle maturation. Dev Biol. 2017;426:84-96 pubmed publisher
..Our results indicate a restricted and likely locus-specific role for Kdm6b demethylases during heart ventricle maturation rather than initial cardiogenesis. ..
Stewart S, Gomez A, Armstrong B, Henner A, Stankunas K. Sequential and opposing activities of Wnt and BMP coordinate zebrafish bone regeneration. Cell Rep. 2014;6:482-98 pubmed publisher
..This hierarchical signaling network model provides a conceptual framework for understanding innate bone repair and regeneration mechanisms and rationally designing regenerative therapeutics. ..
Tallafuss A, Kelly M, Gay L, Gibson D, Batzel P, Karfilis K, et al
. Transcriptomes of post-mitotic neurons identify the usage of alternative pathways during adult and embryonic neuronal differentiation. BMC Genomics. 2015;16:1100 pubmed publisher
..This important insight and the lists of enriched genes we have identified will now help pave the way to a better understanding of the mechanisms of embryonic and adult neuronal differentiation and how to manipulate these processes. ..